標(biāo)題: Titlebook: Glycoprotein Methods and Protocols; The Mucins Anthony P. Corfield Book 2000 Humana Press 2000 [打印本頁] 作者: 變成小松鼠 時(shí)間: 2025-3-21 18:02
書目名稱Glycoprotein Methods and Protocols影響因子(影響力)
書目名稱Glycoprotein Methods and Protocols影響因子(影響力)學(xué)科排名
書目名稱Glycoprotein Methods and Protocols網(wǎng)絡(luò)公開度
書目名稱Glycoprotein Methods and Protocols網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Glycoprotein Methods and Protocols被引頻次
書目名稱Glycoprotein Methods and Protocols被引頻次學(xué)科排名
書目名稱Glycoprotein Methods and Protocols年度引用
書目名稱Glycoprotein Methods and Protocols年度引用學(xué)科排名
書目名稱Glycoprotein Methods and Protocols讀者反饋
書目名稱Glycoprotein Methods and Protocols讀者反饋學(xué)科排名
作者: Occupation 時(shí)間: 2025-3-21 22:41
Separation and Identification of Mucins and Their Glycoformsse mucins share common features in that they are oligomeric in nature and consist of a variable number of monomers (subunits) linked in an end-to-end fashion via the agency of disulfide bonds. In addition, their polypeptides comprise regions of dense glycosylation interspersed with “naked” cysteine-rich domains (.–.).作者: Champion 時(shí)間: 2025-3-22 01:10 作者: 翻動(dòng) 時(shí)間: 2025-3-22 06:02
Identification of Glycosylation Sites in Mucin Peptides by Edman Degradationicroheterogeneity). Typically, the characterization of macro- and microheterogeneity has been dependent on the isolation of small peptides with only one glycosylation site. However, this is not possible with high molecular weight, heavily glycosylated domains such as those found in mucins.作者: 過份艷麗 時(shí)間: 2025-3-22 11:01
Mucin Domains to Explore Disulfide-Dependent Dimer Formationregion of tandem repeat sequences, flanked by cysteine-rich regions at each end, which are presumed to mediate polymerization. Secretory mucins contain approx 60–80% carbohydrate, with extensive .-glycosylation in the central tandem repeat regions, and N-linked oligosaccharides in the peripheral regions (.).作者: 水土 時(shí)間: 2025-3-22 14:36 作者: 水土 時(shí)間: 2025-3-22 20:43 作者: 龍卷風(fēng) 時(shí)間: 2025-3-22 22:45
Detection and Quantitation of Mucins Using Chemical, Lectin, and Antibody Methods starting point for development of a technique. Refer to Chapter 3 for detection of mucins in histological preparations (.); note, however, that many of the principles for selection of detection tools discussed herein are applicable to histological detection.作者: 錢財(cái) 時(shí)間: 2025-3-23 02:58 作者: blister 時(shí)間: 2025-3-23 08:38 作者: Oafishness 時(shí)間: 2025-3-23 09:48 作者: 懦夫 時(shí)間: 2025-3-23 14:23
https://doi.org/10.1007/978-3-662-37854-0no acid peptide bonds within the protein; chemical derivatization of hydrolysate (amino acids) of the protein; and high-performance liquid chromatography (HPLC) separation, detection, and analysis of those derivatized amino acids.作者: catagen 時(shí)間: 2025-3-23 20:08 作者: Lice692 時(shí)間: 2025-3-23 22:31
Allgemeinerkrankungen des Skeletsregion of tandem repeat sequences, flanked by cysteine-rich regions at each end, which are presumed to mediate polymerization. Secretory mucins contain approx 60–80% carbohydrate, with extensive .-glycosylation in the central tandem repeat regions, and N-linked oligosaccharides in the peripheral regions (.).作者: Immobilize 時(shí)間: 2025-3-24 04:36 作者: Rotator-Cuff 時(shí)間: 2025-3-24 10:13
https://doi.org/10.1007/978-3-662-29955-5. It is possible that heterogeneity may be an important biological property of gel-forming mucins and a key comparative characteristic when studying the change of mucous properties through the course of disease.作者: micronized 時(shí)間: 2025-3-24 13:11
Quantitation of Biosynthesis and Secretion of Mucin Using Metabolic Labelingn effective, yet temporary, means of epithelial protection (.,.). Both types of secretion require synthesis of mucin: constitutive secretion demands a continuous low level of biosynthesis, whereas stimulated secretion requires massive synthesis to replenish the diminished resources.作者: 他很靈活 時(shí)間: 2025-3-24 17:21
Heterogeneity and Size Distribution of Gel-Forming Mucins. It is possible that heterogeneity may be an important biological property of gel-forming mucins and a key comparative characteristic when studying the change of mucous properties through the course of disease.作者: airborne 時(shí)間: 2025-3-24 19:09
https://doi.org/10.1007/978-3-642-47356-2 principal issues need to be considered in order to maximize the potential value of morphologically based methodologies: (1) nature and limitations of the individual techniques, and (2) interpretation and reporting of mucin staining.作者: Increment 時(shí)間: 2025-3-25 02:51 作者: 合并 時(shí)間: 2025-3-25 04:24
https://doi.org/10.1007/978-3-642-69232-1the cancer patient. These changes in expression of mucin observed in neoplasia have led to the exploitation of some members of the mucin family as circulating tumor markers (.,.) or targets for diagnostic imaging (.–.) and therapy of cancer.作者: Nonthreatening 時(shí)間: 2025-3-25 10:42
Histologically Based Methods for Detection of Mucin principal issues need to be considered in order to maximize the potential value of morphologically based methodologies: (1) nature and limitations of the individual techniques, and (2) interpretation and reporting of mucin staining.作者: COM 時(shí)間: 2025-3-25 13:38 作者: 秘傳 時(shí)間: 2025-3-25 16:29 作者: 噱頭 時(shí)間: 2025-3-25 22:13
Anthony P. CorfieldIncludes supplementary material: 作者: 案發(fā)地點(diǎn) 時(shí)間: 2025-3-26 00:46
https://doi.org/10.1007/978-3-7091-7858-4genes (., and .) have been identified (for reviews ... and ., with each gene showing expression in several tissues. Only the ., and . mucins have been sequenced completely (.–.) although large stretches of . (.–.) as well as the C-terminal sequences of . (.) and . (.) are now known.作者: Foment 時(shí)間: 2025-3-26 07:55 作者: 松軟 時(shí)間: 2025-3-26 12:15 作者: 討好美人 時(shí)間: 2025-3-26 16:13
https://doi.org/10.1007/978-3-7091-7858-4genes (., and .) have been identified (for reviews ... and ., with each gene showing expression in several tissues. Only the ., and . mucins have been sequenced completely (.–.) although large stretches of . (.–.) as well as the C-terminal sequences of . (.) and . (.) are now known.作者: enlist 時(shí)間: 2025-3-26 19:33 作者: DEVIL 時(shí)間: 2025-3-26 22:19 作者: 和平主義者 時(shí)間: 2025-3-27 02:32
Kurvendarstellung im rechtwinkligen Netz novel mucins present during purification from mucus, to quantitation of specific mucin core proteins or carbohydrate moieties present in clinical samples. This chapter discusses procedures and limitations of several different strategies available to detect and quantify these glycoproteins from biol作者: 小說 時(shí)間: 2025-3-27 06:54 作者: Invertebrate 時(shí)間: 2025-3-27 10:40
https://doi.org/10.1007/978-3-662-29957-9complex glycoproteins (.,.). These secretory mucins form mucous layers on the apical side of the cells, protecting the vulnerable epithelium, while allowing selective interactions with the apical environments, which is typically the lumen of an organ that is continuous with the outer world. Secretio作者: 使人煩燥 時(shí)間: 2025-3-27 15:20 作者: 相一致 時(shí)間: 2025-3-27 21:40
https://doi.org/10.1007/978-3-662-29955-5orming mucins. These molecules share the ability to assemble into long oligomeric structures via the agency of disulfide bonds. There is evidence that at least four mucins—MUC2, MUC5AC, MUC5B, and MUC6 (.–.)—are gel-forming mucins, and it is possible that there are others. In isolating a mixture of 作者: HAIRY 時(shí)間: 2025-3-27 23:18
,Die Erkrankungen des ?u?eren Ohres,urfaces from damaging effects and agents (..,.). Mucous gels are not pure mucin but contain other components secreted into the gel, e.g., IgA and protein, lipid, and nucleic acid from shed epithelial cells, and particularly, in the lower GI tract from bacteria. When measuring the rheological propert作者: AGONY 時(shí)間: 2025-3-28 05:12 作者: 卵石 時(shí)間: 2025-3-28 08:19
Aliphatische Schwefelverbindungen,tion), it is challenging to assign the sites of glycosylation (macroheterogeneity) and the carbohydrate heterogeneity at a given glycosylation site (microheterogeneity). Typically, the characterization of macro- and microheterogeneity has been dependent on the isolation of small peptides with only o作者: Phonophobia 時(shí)間: 2025-3-28 14:09
https://doi.org/10.1007/978-3-642-69232-1ancer research. Mucins, which are constituents of mucus, have a lubricating and protective function in normal epithelial tissue (.). However, expression of mucin by the cancer cell is often highly disorganized and upregulated, sometimes to the extent that mucin can be detected in the circulation of 作者: 橢圓 時(shí)間: 2025-3-28 17:27 作者: 全面 時(shí)間: 2025-3-28 19:47
Isolation of Large Gel-Forming Mucinsgenes (., and .) have been identified (for reviews ... and ., with each gene showing expression in several tissues. Only the ., and . mucins have been sequenced completely (.–.) although large stretches of . (.–.) as well as the C-terminal sequences of . (.) and . (.) are now known.作者: libertine 時(shí)間: 2025-3-29 02:20 作者: iodides 時(shí)間: 2025-3-29 06:04 作者: AMPLE 時(shí)間: 2025-3-29 09:40 作者: FRET 時(shí)間: 2025-3-29 13:39
The Gastrointestinal Adherent Mucous Gel Barriered, intracellular mucin; the gel phase adherent to the epithelial surfaces; and the viscous, mobile mucin, which is largely in soluble form and mixes with the luminal contents. The layer of adherent mucous gel that lines the epithelial surfaces throughout the gut from the stomach to the colon marks 作者: HILAR 時(shí)間: 2025-3-29 19:31
Quantitation of Biosynthesis and Secretion of Mucin Using Metabolic Labelingcomplex glycoproteins (.,.). These secretory mucins form mucous layers on the apical side of the cells, protecting the vulnerable epithelium, while allowing selective interactions with the apical environments, which is typically the lumen of an organ that is continuous with the outer world. Secretio作者: PURG 時(shí)間: 2025-3-29 21:57 作者: braggadocio 時(shí)間: 2025-3-30 00:39