標題: Titlebook: Glial Amino Acid Transporters; Arturo Ortega,Arne Schousboe Book 2017 Springer International Publishing AG 2017 Amino Acid Transporters.GA [打印本頁] 作者: TIBIA 時間: 2025-3-21 19:16
書目名稱Glial Amino Acid Transporters影響因子(影響力)
書目名稱Glial Amino Acid Transporters影響因子(影響力)學科排名
書目名稱Glial Amino Acid Transporters網(wǎng)絡公開度
書目名稱Glial Amino Acid Transporters網(wǎng)絡公開度學科排名
書目名稱Glial Amino Acid Transporters被引頻次
書目名稱Glial Amino Acid Transporters被引頻次學科排名
書目名稱Glial Amino Acid Transporters年度引用
書目名稱Glial Amino Acid Transporters年度引用學科排名
書目名稱Glial Amino Acid Transporters讀者反饋
書目名稱Glial Amino Acid Transporters讀者反饋學科排名
作者: 不可救藥 時間: 2025-3-21 21:54
Molecular Characteristics, Regulation, and Function of Monocarboxylate Transporters,ressed. Recent evidence shows their participation in important brain functions that involve intercellular communication, such as hypothalamic glucose sensing. Furthermore, we describe the regulation of their expression and some animal models that have allowed clarification of their functions.作者: Projection 時間: 2025-3-22 04:22
https://doi.org/10.1007/978-3-319-55769-4Amino Acid Transporters; GABA; Gene Expression Regulation; Glia Cells; Signaling作者: critic 時間: 2025-3-22 04:39 作者: Glycogen 時間: 2025-3-22 10:03 作者: 教育學 時間: 2025-3-22 16:41
Arturo Ortega,Arne SchousboeComprehensive look at glia amino acid transporters.Includes sections on structural aspects, functional properties, and gene expression regulation.Discusses illnesses related to glia amino acid transpo作者: 教育學 時間: 2025-3-22 19:59
,Manganese Control of Glutamate Transporters’ Gene Expression,n body. However, chronic overexposure to Mn from occupational or environmental sources induces a neurological disorder, characterized by psychiatric, cognitive, and motor abnormalities, referred to as manganism. Mn-induced neurotoxicity is known to target astrocytes since these cells preferentially 作者: micronized 時間: 2025-3-23 01:15 作者: Spirometry 時間: 2025-3-23 04:07 作者: inferno 時間: 2025-3-23 09:37
Glycine Transporters and Its Coupling with NMDA Receptors,n all regions of the CNS, it also works as a co-agonist with L-glutamate at N-methyl-D-aspartate receptors (NMDARs). The glycine fluxes in the CNS are regulated by two specific transporters for glycine, GlyT1 and GlyT2, perhaps with the cooperation of diverse neutral amino acid transporters like Asc作者: KEGEL 時間: 2025-3-23 13:43
Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters,orters (SLC6A1, SLC6A11, SLC6A12, SLC6A13) and how the revised stoichiometry impacts our understanding of the contribution of GABA transporters to GABA homeostasis in synaptic and extrasynaptic regions in the brain under physiological and pathophysiological states. Recently, our laboratory probed th作者: 壕溝 時間: 2025-3-23 16:22
EAAT2 and the Molecular Signature of Amyotrophic Lateral Sclerosis,ely heterogeneous disease in both cause and symptom development, and its mechanisms of pathogenesis remain largely unknown. Excitotoxicity, a process caused by excessive glutamate signaling, is believed to play a substantial role, however. Excessive glutamate release, changes in postsynaptic glutama作者: 漸強 時間: 2025-3-23 18:30
Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke, through pharmacological intervention with extrasynaptic GABA. receptors that sense ambient GABA and mediate a persistent GABAergic conductance. An increase in tonic inhibition may, however, also be obtained indirectly by inhibiting glial GABA transporters (GATs). These are sodium-coupled membrane t作者: 矛盾心理 時間: 2025-3-23 22:36 作者: 1FAWN 時間: 2025-3-24 02:38 作者: geriatrician 時間: 2025-3-24 07:23 作者: 1分開 時間: 2025-3-24 11:10
Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain: Molecular Mechanisms and a chemical transmitter of excitation. High-affinity glutamate transporter subtypes GLAST/EAAT1, GLT1/EAAT2, EAAC1/EAAT3, and EAAT4, differentially expressed on sensory neurons, postsynaptic spinal interneurons, and neighboring glia, ensure fine modulation of glutamate neurotransmission in the spina作者: 異教徒 時間: 2025-3-24 16:13 作者: 持久 時間: 2025-3-24 21:36
Glial Excitatory Amino Acid Transporters and Glucose Incorporation,manner, astrocytes preserve the signaling functions mediated by glutamate on synapses and prevent excitotoxicity. Additionally, EAAT activation stimulates glucose utilization in astrocytes, linking neuronal activity with astrocyte metabolism. In this chapter, we briefly review the characteristics of作者: fulmination 時間: 2025-3-25 02:41 作者: 出價 時間: 2025-3-25 07:01 作者: Herbivorous 時間: 2025-3-25 08:55
Development of Non-GAT1-Selective Inhibitors: Challenges and Achievements,. Four different transporters have been identified: GAT1, GAT2, GAT3, and the betaine/GABA transporter 1 (BGT1). The GAT1 subtype is the most explored transporter due to its high abundance in the brain and the existence of selective and potent GAT1 inhibitors. Consequently, less is known about the r作者: ascetic 時間: 2025-3-25 14:43
,Auswahl der Transformatoren?le bei der AEG,n body. However, chronic overexposure to Mn from occupational or environmental sources induces a neurological disorder, characterized by psychiatric, cognitive, and motor abnormalities, referred to as manganism. Mn-induced neurotoxicity is known to target astrocytes since these cells preferentially 作者: bromide 時間: 2025-3-25 15:55
,Hohe Wechselspannungen und -str?me, also a positive neuromodulator at excitatory glutamate-mediated synapses. Glial cells provide metabolic support to neurons and modulate synaptic activity. Six transporters belonging to three solute carrier families (SLC6, SLC38, and SLC7) are capable of transporting glycine across the glial plasma 作者: 兵團 時間: 2025-3-25 22:19
Grundlagen der Teilentladungsmesstechnik,ly critical in the brain. Taurine participates in osmotic adjustments required to maintain the organization and size of intracellular compartments. It counteracts volume fluctuations in unbalanced transmembrane fluxes of ions and neurotransmitters, preserving the functional synaptic contacts. Taurin作者: CRUC 時間: 2025-3-26 00:11 作者: 合群 時間: 2025-3-26 04:27 作者: –scent 時間: 2025-3-26 08:56
,?l im Zusammenbau mit festen Baustoffen,ely heterogeneous disease in both cause and symptom development, and its mechanisms of pathogenesis remain largely unknown. Excitotoxicity, a process caused by excessive glutamate signaling, is believed to play a substantial role, however. Excessive glutamate release, changes in postsynaptic glutama作者: callous 時間: 2025-3-26 13:44 作者: Metamorphosis 時間: 2025-3-26 18:48
,Der Lichtbogen in Luft und unter ?l,mbrane proteins is the cerebellum. The most abundant glutamatergic synapse in the central nervous system is present in the molecular layer of the cerebellar cortex, and it is entirely wrapped by Bergmann glial cells. The recycling of glutamate involves glutamate and glutamine transporters enriched i作者: 提名的名單 時間: 2025-3-26 22:55
,überspannungen und Wanderwellen, system by maintaining the neurotransmitter’s baseline levels after its release. The major excitatory neurotransmitter in the central nervous system is glutamate; its extracellular levels are tightly regulated through high-affinity plasma membrane transporters. Most of the brain glutamate uptake act作者: 蒸發(fā) 時間: 2025-3-27 02:08 作者: 懸掛 時間: 2025-3-27 07:57 作者: 殺菌劑 時間: 2025-3-27 10:46 作者: Blanch 時間: 2025-3-27 14:49 作者: Dictation 時間: 2025-3-27 21:21
Technische Physik in Einzeldarstellungenytes. Early studies of the pharmacological properties of neuronal and glial GABA transporters suggested that different types of transporters might be expressed in the two cell types, and such a scenario was confirmed by the cloning of four distinctly different GABA transporters from a number of diff作者: Amorous 時間: 2025-3-28 00:47 作者: animated 時間: 2025-3-28 04:37 作者: 動作謎 時間: 2025-3-28 10:17
,?l im Zusammenbau mit festen Baustoffen,compounds that increase the functional excitatory amino acid transporter EAAT2 (GLT1), which is responsible for the vast majority of glutamate clearance. One such compound, ceftriaxone, was recently tested in clinical trials but unfortunately did not modify disease course, though its effect on EAAT2 expression in patients was not measured.作者: 好開玩笑 時間: 2025-3-28 14:27
,Der Lichtbogen in Luft und unter ?l,al glutamate and glutamine transporters follows, and a working model of the molecular mechanisms by which these glutamate and glutamine binding proteins interact, and by these means might modulate cerebellar glutamatergic transactions, is presented.作者: FLIRT 時間: 2025-3-28 16:17
https://doi.org/10.1007/978-3-658-07458-6y which the activity of GLUTs could be modulated after EAAT activation (e.g., kinases altering GLUTs traffic to cell membrane). Finally, we analyzed the current knowledge on EAAT function during energy deficiency as a possible inducer of GLUT expression to prevent neuronal damage.作者: 無動于衷 時間: 2025-3-28 22:42 作者: 消毒 時間: 2025-3-29 01:39 作者: artifice 時間: 2025-3-29 05:16
Glutamine/Glutamate Transporters in Glial Cells: Much More Than Participants of a Metabolic Shuttleal glutamate and glutamine transporters follows, and a working model of the molecular mechanisms by which these glutamate and glutamine binding proteins interact, and by these means might modulate cerebellar glutamatergic transactions, is presented.作者: verdict 時間: 2025-3-29 07:45
Glial Excitatory Amino Acid Transporters and Glucose Incorporation,y which the activity of GLUTs could be modulated after EAAT activation (e.g., kinases altering GLUTs traffic to cell membrane). Finally, we analyzed the current knowledge on EAAT function during energy deficiency as a possible inducer of GLUT expression to prevent neuronal damage.作者: 肉身 時間: 2025-3-29 14:42
Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs,of the validity of this drug development approach, one GABA-transport inhibitor, tiagabine, has been developed as a clinically active antiepileptic drug. This review provides a detailed account of efforts to design new subtype-selective GABA-transport inhibitors aiming at identifying novel antiepileptic drug candidates.作者: Cabg318 時間: 2025-3-29 18:11 作者: 轉(zhuǎn)向 時間: 2025-3-29 21:21
Book 2017ir involvement in signaling and gene expression regulation, this volume presents the most recent research on the roles of glial amino acid transporters as key molecules of brain metabolism and signaling.?作者: FLORA 時間: 2025-3-30 03:26
,Hochspannungsanlagen für Wechselstrom,to provide an overview of glial GATs in regulating tonic inhibition, especially in epilepsy and stroke. This entails a comprehensive summary of changes known to occur in GAT expression levels and signalling following epileptic and ischemic insults. Further, we discuss the accumulating pharmacological evidence for targeting GATs in these diseases.作者: LIMN 時間: 2025-3-30 05:29
Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke,to provide an overview of glial GATs in regulating tonic inhibition, especially in epilepsy and stroke. This entails a comprehensive summary of changes known to occur in GAT expression levels and signalling following epileptic and ischemic insults. Further, we discuss the accumulating pharmacological evidence for targeting GATs in these diseases.作者: arbovirus 時間: 2025-3-30 10:41
Book 2017hich far outnumber neurons but are much less understood. Covering multiple aspects of this family of transporters-- from structural properties, to their involvement in signaling and gene expression regulation, this volume presents the most recent research on the roles of glial amino acid transporter作者: 破譯 時間: 2025-3-30 16:16
2190-5215 family of transporters-- from structural properties, to their involvement in signaling and gene expression regulation, this volume presents the most recent research on the roles of glial amino acid transporters as key molecules of brain metabolism and signaling.?978-3-319-85741-1978-3-319-55769-4Series ISSN 2190-5215 Series E-ISSN 2190-5223 作者: 1FAWN 時間: 2025-3-30 19:16 作者: Cardioversion 時間: 2025-3-30 21:13
,Hohe Wechselspannungen und -str?me,ted fold originally characterized in the leucine transporter LeuT. The availability of protein crystals solved at high resolution for prokaryotic and, more recently, eukaryotic homologues of this superfamily has advanced significantly our understanding of the mechanism of glycine transport.作者: 單調(diào)性 時間: 2025-3-31 02:14
Grundlagen der Teilentladungsmesstechnik,r. The brain taurine pool results from the equilibrium between (.) dietary intake and active transport into the cell, (.) synthesis in the brain itself or import of that synthesized elsewhere, and (.) leak and posterior excretion. The interplay between these elements preserves brain taurine homeosta作者: Vo2-Max 時間: 2025-3-31 05:36 作者: 整體 時間: 2025-3-31 12:55
Wolfgang Hauschild,Eberhard Lemken of Na., Cl., and GABA were 84 ± 4, 30 ± 1, and 29 ± 1 mV, respectively. Charge flux to substrate flux ratios were 0.7 ± 0.1 charges/Na., 2.0 ± 0.2 charges/Cl., and 2.1 ± 0.1 charges/GABA. We then compared these experimental results with the predictions of 150 different transporter stoichiometry mo作者: 蓋他為秘密 時間: 2025-3-31 15:05
,überspannungen und Wanderwellen,able amount of evidences suggesting an important intervention of these transporter proteins in glutamate signaling, mainly in glial cells, has been accumulated. Herein we provide a summary or the most important findings in this novel function of glial glutamate transporters as signal transduction en作者: STIT 時間: 2025-3-31 17:32 作者: COKE 時間: 2025-4-1 00:27
,?l im Zusammenbau mit festen Baustoffen,t, upregulation of GluTs by positive pharmacological modulators or by viral gene transfer to the spinal cord can reverse the development of such pathological hypersensitivity. Furthermore, some multi-target drugs displaying analgesic properties (e.g., tricyclic antidepressant amitriptyline, riluzole
