標(biāo)題: Titlebook: Glaucoma; Methods and Protocol Tatjana C. Jakobs Book 2018 Springer Science+Business Media LLC 2018 Intraocular pressure.Neuroprotection.Op [打印本頁(yè)] 作者: ATE 時(shí)間: 2025-3-21 19:51
書(shū)目名稱(chēng)Glaucoma影響因子(影響力)
作者: Toxoid-Vaccines 時(shí)間: 2025-3-21 23:33
3D Histomorphometric Reconstruction and Quantification of the Optic Nerve Head Connective Tissues,作者: 虛度 時(shí)間: 2025-3-22 03:10
https://doi.org/10.1007/978-1-4684-1587-2mation and scarring of the anterior chamber angle occurs gradually, resulting in a rise in IOP after approximately 1 week. This article will describe the equipment necessary for producing this model and the steps of the technique itself.作者: NICE 時(shí)間: 2025-3-22 05:52
https://doi.org/10.1007/978-3-642-71010-0harmacological manipulations, we have analyzed ER stress and UPR mediators in the glaucomatous TM damage and IOP elevation. In this chapter, we have described a detailed protocol for the analysis of protein misfolding and ER stress in TM cells and tissues and its association with glaucomatous TM dam作者: cumber 時(shí)間: 2025-3-22 09:43
Hypertonic Saline Injection Model of Experimental Glaucoma in Rats,mation and scarring of the anterior chamber angle occurs gradually, resulting in a rise in IOP after approximately 1 week. This article will describe the equipment necessary for producing this model and the steps of the technique itself.作者: 光明正大 時(shí)間: 2025-3-22 13:52 作者: 光明正大 時(shí)間: 2025-3-22 20:20
Perspectives and Advances in Photocatalysis,This chapter provides an overview over the use of animal models in glaucoma research from a historical perspective. Strengths and limitations of various models are considered, and the challenges of translating results in animal experiments to successful clinical trials in humans are discussed.作者: GREG 時(shí)間: 2025-3-23 00:22 作者: 培養(yǎng) 時(shí)間: 2025-3-23 05:07 作者: 根除 時(shí)間: 2025-3-23 07:41 作者: 的是兄弟 時(shí)間: 2025-3-23 12:50
978-1-4939-8476-3Springer Science+Business Media LLC 2018作者: febrile 時(shí)間: 2025-3-23 14:43 作者: 有害處 時(shí)間: 2025-3-23 18:18 作者: In-Situ 時(shí)間: 2025-3-24 00:18
https://doi.org/10.1007/978-1-4939-7407-8Intraocular pressure; Neuroprotection; Ophthalmology; Therapeutic approaches; Retinal ganglion cells; Eye作者: 生命層 時(shí)間: 2025-3-24 02:47 作者: 較早 時(shí)間: 2025-3-24 07:54 作者: Kinetic 時(shí)間: 2025-3-24 11:41
Investigation of the Functional Retinal Output Using Microelectrode Arrays, of a large portion of retinal ganglion cells (RGCs) is recorded simultaneously in response to various light stimuli. Analysis of the recorded time series of action potentials reveals physiological parameters such as firing rate, time latency, receptive field size, axonal conduction velocity. These parameters change during retinal diseases.作者: 闡明 時(shí)間: 2025-3-24 16:58
Shotgun Sphingolipid Analysis of Human Aqueous Humor,ethod and electrospray ionization tandem mass spectrometry (ESI-MS/MS) coupled with MZmine 2.21 data processing for identification and ratiometric quantitation of sphingosine, sphingosine-1-phosphate, sphingomyelin, and ceramide.作者: Vertical 時(shí)間: 2025-3-24 21:07
Book 2018that the retinal ganglion cells damaged and destroyed by glaucoma do not regenerate after lowering the intraocular pressure, new therapeutic approaches that protect ganglion cells directly is a vital research goal that this volume’s contents aim to aid scientists in developing. Written in the highly作者: 軍械庫(kù) 時(shí)間: 2025-3-25 03:01
1064-3745 ns key notes and implementation advice from the expertsThis detailed volume introduces the reader to current methods in glaucoma research, in particular those that make use of animal disease models. Given that the retinal ganglion cells damaged and destroyed by glaucoma do not regenerate after lower作者: 改變立場(chǎng) 時(shí)間: 2025-3-25 03:27
Heterogeneous and Liquid Phase Processesls uses methods that have been adapted from use on humans. Calibration of the instruments used for the specific animal and even strain used is critically important for allowing meaningful comparisons of results. We describe below the methods used for noninvasive IOP measurement in animals that are relevant to glaucoma research.作者: jocular 時(shí)間: 2025-3-25 10:37
,Durchführung der Simulationsstudie,y (UHPLC-MS/MS) and data analysis for peptide identification and quantitation using Proteome Discoverer software. The protocol can be applied for other animals as well; however, pooling of specimens may be required to obtain sufficient amount of protein for labeling.作者: 不再流行 時(shí)間: 2025-3-25 14:27 作者: 公理 時(shí)間: 2025-3-25 16:45
Chenxin Zhang,Liang Liu,Viktor ?walln Model in mice. We highlight the importance of anesthesia choice and the utilization of glass micropipettes in combination with a micromanipulator and microsyringe pump for the successful execution of the model.作者: 先驅(qū) 時(shí)間: 2025-3-25 20:44 作者: hyperuricemia 時(shí)間: 2025-3-26 00:46
The Microbead Occlusion Model of Ocular Hypertension in Mice,n Model in mice. We highlight the importance of anesthesia choice and the utilization of glass micropipettes in combination with a micromanipulator and microsyringe pump for the successful execution of the model.作者: visual-cortex 時(shí)間: 2025-3-26 05:52 作者: prediabetes 時(shí)間: 2025-3-26 09:28 作者: 寄生蟲(chóng) 時(shí)間: 2025-3-26 16:01 作者: 有惡臭 時(shí)間: 2025-3-26 17:14 作者: 諄諄教誨 時(shí)間: 2025-3-26 21:22
Alexander A. Ignatiev,Alexander V. Lyashenkora, using second harmonic generation microscopy and small-angle light scattering. Together, these approaches allow specimen-specific measurement of tissue stiffness and collagen alignment, which are key factors in determining how the eye responds to mechanical loads.作者: 的闡明 時(shí)間: 2025-3-27 01:39
Raimo Tuomelas Quasi-Ontologie des Sozialen,the labeled tissue. Quantification of dendritic and synaptic properties permits examination of the specific alterations to RGC morphology at different stages of degeneration, such as dendritic shrinkage and excitatory synapse loss.作者: Matrimony 時(shí)間: 2025-3-27 05:22
Bettina Fritzsche,Jutta Hartmannneonatal RGCs, dissociated mature retinal neurons, retinal explants) and in vivo models that test potential treatments or investigate underlying molecular mechanisms in an intact system. Potentially, use of these models can help investigators continue to improve treatments to preserve RGCs and restore visual function in patients with glaucoma.作者: 裂縫 時(shí)間: 2025-3-27 10:55
Ocular Hypertension/Glaucoma in Minipigs: Episcleral Veins Cauterization and Microbead Occlusion Mee second method is the multiple injection of microbeads into the anterior chamber, as a pre and intra-trabecular method that induce secondary effects on the TM cells. Both methods lead to an increase in IOP.作者: Etching 時(shí)間: 2025-3-27 13:42 作者: 演繹 時(shí)間: 2025-3-27 21:49
Assessment of Aqueous Humor Dynamics in the Rodent by Constant Flow Infusion,he determination of all principal parameters of aqueous humor dynamics (intraocular pressure (IOP), aqueous humor formation rate (Fin), uveoscleral outflow rate (Fu), aqueous outflow facility (C), and episcleral venous pressure (Pe)) in the living rat and mouse eye, in a single experimental session.作者: 初學(xué)者 時(shí)間: 2025-3-27 23:06 作者: 禮節(jié) 時(shí)間: 2025-3-28 04:25 作者: Pericarditis 時(shí)間: 2025-3-28 09:43 作者: PSA-velocity 時(shí)間: 2025-3-28 13:54 作者: Synchronism 時(shí)間: 2025-3-28 14:36 作者: etiquette 時(shí)間: 2025-3-28 18:58 作者: FIG 時(shí)間: 2025-3-29 02:45
Noninvasive Intraocular Pressure Measurement in Animals Models of Glaucoma,ls uses methods that have been adapted from use on humans. Calibration of the instruments used for the specific animal and even strain used is critically important for allowing meaningful comparisons of results. We describe below the methods used for noninvasive IOP measurement in animals that are relevant to glaucoma research.作者: 溝通 時(shí)間: 2025-3-29 06:00
Quantitative Proteomic Analysis of Human Aqueous Humor Using iTRAQ 4plex Labeling,y (UHPLC-MS/MS) and data analysis for peptide identification and quantitation using Proteome Discoverer software. The protocol can be applied for other animals as well; however, pooling of specimens may be required to obtain sufficient amount of protein for labeling.作者: MENT 時(shí)間: 2025-3-29 09:33
Anterograde Tract Tracing for Assaying Axonopathy and Transport Deficits in Glaucoma,ibe the use of anterograde neuronal tract tracing using cholera toxin B (CTB) for the determination of axon transport integrity of the retinofugal projection. This method reveals the structure of the retinal axons as well as the functional integrity of anterograde transport systems.作者: 繁殖 時(shí)間: 2025-3-29 13:39
https://doi.org/10.1007/978-1-4684-1587-2ms of optic nerve injury that occur in glaucoma. In addition, such a model could provide a valuable method for testing potential neuroprotective treatments. This paper outlines the basic methods for producing obstruction of aqueous humor outflow and IOP elevation by injecting hypertonic saline (a sc作者: 翻布尋找 時(shí)間: 2025-3-29 17:46
Chenxin Zhang,Liang Liu,Viktor ?wallation in glaucoma is associated with sensitivity to intraocular pressure (IOP) and elevated IOP (also known as ocular hypertension) is the primary modifiable risk factor. Ocular hypertension is the primary characteristic of rodent models for glaucoma research. Intracameral injection of microbeads ha作者: arousal 時(shí)間: 2025-3-29 23:12
Fei Richard Yu,Helen Tang,Hong Ji increasing the post-trabecular resistance to aqueous outflow by cauterizing the episcleral veins (EVC). This method allows the observation of ultrastructural changes in the trabecular meshwork (TM) without interfering with any structure within the eye such as TM, ciliary body, and/or the Retina. Th作者: Pessary 時(shí)間: 2025-3-30 02:29
Heterogeneous and Liquid Phase Processes the disease is important for any research work trying to understand the pathophysiologic mechanisms of glaucoma. Noninvasive IOP measurement in animals uses methods that have been adapted from use on humans. Calibration of the instruments used for the specific animal and even strain used is critica作者: Ligament 時(shí)間: 2025-3-30 06:58 作者: Urea508 時(shí)間: 2025-3-30 09:50 作者: 不連貫 時(shí)間: 2025-3-30 12:57
,Durchführung der Simulationsstudie,re, we describe iTRAQ 4plex labeling of human aqueous humor specimens followed by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) and data analysis for peptide identification and quantitation using Proteome Discoverer software. The protocol can be applied for othe作者: 向宇宙 時(shí)間: 2025-3-30 16:53 作者: 消瘦 時(shí)間: 2025-3-30 23:15 作者: conference 時(shí)間: 2025-3-31 04:32
https://doi.org/10.1007/978-3-642-71010-0sure (IOP) have not been fully delineated. Recent studies have shown that progressive accumulation of misfolded proteins and induction of endoplasmic reticulum (ER) stress is associated with the pathophysiology of glaucomatous TM damage and IOP elevation. We have shown that known causes of human gla作者: Scleroderma 時(shí)間: 2025-3-31 08:38 作者: 毛細(xì)血管 時(shí)間: 2025-3-31 09:16
Raimo Tuomelas Quasi-Ontologie des Sozialen,inal ganglion cells (RGCs) allows visualization of dendritic and synaptic structures of RGCs in retinal explants from animal models of experimental glaucoma. This technique sparsely labels RGCs, and, due to the stochastic nature of the particle delivery, all RGC types can be potentially observed in 作者: 卷發(fā) 時(shí)間: 2025-3-31 13:31 作者: 長(zhǎng)處 時(shí)間: 2025-3-31 21:27
Bettina Fritzsche,Jutta Hartmannye. Because RGCs are not replaced and because surviving RGCs cannot regenerate their axons, the visual loss in glaucoma is largely irreversible. Here, we describe methods to evaluate treatments that may be beneficial for treating glaucoma using in vitro cell culture models (immunopanning to isolate 作者: cataract 時(shí)間: 2025-3-31 22:16
https://doi.org/10.1007/978-3-642-73590-5 to brain physiology and perform many functions that are important for normal neuronal development and metabolism, synapse formation, synaptic transmission, and in repair following injury/disease. Astrocytes also communicate with neurons, blood vessels, and other types of glial cells. Astrocytes wit作者: obeisance 時(shí)間: 2025-4-1 02:09
Nutrient Interactions and Microbes,tial role in the regulation of the complex biological responses that develop in response to elevated intraocular pressure. However, contemporary microRNA assay techniques (e.g., microarrays and next-generation sequencing) typically require large amounts of RNA template that are often times difficult作者: acheon 時(shí)間: 2025-4-1 08:17
