標題: Titlebook: Genotoxicology of N-Nitroso Compounds; T. K. Rao,W. Lijinsky,J. L. Epler Book 1984 Plenum Press, New York 1984 Mamma.Salmonella.cancer.env [打印本頁] 作者: 滲漏 時間: 2025-3-21 19:20
書目名稱Genotoxicology of N-Nitroso Compounds影響因子(影響力)
書目名稱Genotoxicology of N-Nitroso Compounds影響因子(影響力)學(xué)科排名
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書目名稱Genotoxicology of N-Nitroso Compounds網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Genotoxicology of N-Nitroso Compounds被引頻次
書目名稱Genotoxicology of N-Nitroso Compounds被引頻次學(xué)科排名
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書目名稱Genotoxicology of N-Nitroso Compounds年度引用學(xué)科排名
書目名稱Genotoxicology of N-Nitroso Compounds讀者反饋
書目名稱Genotoxicology of N-Nitroso Compounds讀者反饋學(xué)科排名
作者: 不自然 時間: 2025-3-21 23:24 作者: 臆斷 時間: 2025-3-22 00:42 作者: 開頭 時間: 2025-3-22 06:18
Book 1984tions in genetic toxicology, and a glossary of terms in genetic toxicology. All of these books are in various stages of development and should appear within the next few years. Frederick J. de Serres Series Editor vii Preface During the past ten years there has been an explosive development in the n作者: 密切關(guān)系 時間: 2025-3-22 10:51 作者: 軌道 時間: 2025-3-22 16:56 作者: 軌道 時間: 2025-3-22 19:10
https://doi.org/10.1007/978-3-322-98830-0o difficult to detect in other mutagenicity assays. Dimethylnitrosamine (DMN), however, is negative in the standard . plate incorporation assay,. although it is positive in a variety of other types of mutagenicity tests. DMN is carcinogenic in at least 12 different animal species..作者: 杠桿 時間: 2025-3-23 00:53 作者: Inveterate 時間: 2025-3-23 03:37 作者: Autobiography 時間: 2025-3-23 06:05
Dimethylnitrosamine Demethylase and the Mutagenicity of Dimethylnitrosamine,o difficult to detect in other mutagenicity assays. Dimethylnitrosamine (DMN), however, is negative in the standard . plate incorporation assay,. although it is positive in a variety of other types of mutagenicity tests. DMN is carcinogenic in at least 12 different animal species..作者: 不溶解 時間: 2025-3-23 11:51
Structure-Activity Relations in Carcinogenesis by N-Nitroso Compounds,structures have been carried out with the aim of using the differences in activity to suggest possible mechanisms of their carcinogenic action. This approach, which is common in pharmacology, has proved very useful.作者: 慢慢沖刷 時間: 2025-3-23 16:17
Faraday als der Begründer der Feldtheoriea nitrosamine are replaced with methyl groups, both carcinogenicity. and mutagenicity. are drastically reduced. Replacement of the .-hydrogens with deuterium also results in a reduction in carcinogenic potency..作者: florid 時間: 2025-3-23 18:57 作者: 姑姑在炫耀 時間: 2025-3-24 00:47
The Relationship between Metabolism and Mutagenicity of Two Cyclic Nitrosamines,a nitrosamine are replaced with methyl groups, both carcinogenicity. and mutagenicity. are drastically reduced. Replacement of the .-hydrogens with deuterium also results in a reduction in carcinogenic potency..作者: 小卷發(fā) 時間: 2025-3-24 03:27
Comparison of Mutagenic and Carcinogenic Properties,ons of each test system have become topics of scientific investigation and discussion, especially because of the role they play in regulatory policies. The purpose of organizing this volume was an attempt to examine and compare the genotoxic properties of one extensively studied class of compounds, namely, N-nitroso compounds.作者: 到婚嫁年齡 時間: 2025-3-24 09:53 作者: Picks-Disease 時間: 2025-3-24 11:37
https://doi.org/10.1007/978-3-7091-7712-9s that damage DNA can thus be monitored by looking for the appearance of bacteriophage. Other SOS functions that have been monitored after DNA damage include mutagenesis, filamentation, and DNA repair activity..作者: Graduated 時間: 2025-3-24 16:00
Effects of pH and Structure on the Mutagenic Activity of N-Nitroso Compounds,itions..The contribution to human cancer caused by continued exposure to low levels of N-nitroso compounds is uncertain, but exposure of pregnant mice to levels of 10 ppb of DMN resulted in significant lung tumor formation in the male progeny.. A generalized scheme for the metabolism and decomposition of N-nitroso compounds is given in Figure 1..作者: 可忽略 時間: 2025-3-24 23:02 作者: 桶去微染 時間: 2025-3-25 02:18
https://doi.org/10.1007/978-3-642-92445-3e adverse biological effects until 1937, when a case of poisoning by N-nitrosodimethylamine was reported but largely ignored.. A detailed investigation of the toxicity of nitrosodimethylamine began in England in the 1950s as a result of another accidental poisoning, the first results being reported 作者: landmark 時間: 2025-3-25 05:12 作者: Lipoma 時間: 2025-3-25 10:12 作者: 不要不誠實 時間: 2025-3-25 14:50
https://doi.org/10.1007/978-3-642-60828-5 practical interest to researchers for a number of reasons, such as their organo-tropic tumor induction, the large variability in the potencies and target organs of various N-nitroso compounds, the relatively simple metabolism and breakdown of the lower molecular weight compounds, and the fact that 作者: Flustered 時間: 2025-3-25 17:05
https://doi.org/10.1007/978-3-7091-7712-9ppears to be mediated by the . protein,. resulting in the cleavage of the lambda repressors. and ensuing expression of phage genes. The repressor-cleavage activity of the . protein is dependent on the presence of single-stranded DNA,. presumably generated as a result of DNA damage. DNA damage, then,作者: MELON 時間: 2025-3-25 20:33
https://doi.org/10.1007/978-3-7985-1938-1han 80% of human cancers are caused by exposure to chemical agents.. One class of chemicals that could pose a significant human health hazard is the N-nitroso compounds. These compounds are widespread in our environment,. occurring in food preservatives,. milk,. tobacco smoke,. meat-curing mixtures,作者: Detonate 時間: 2025-3-26 02:31
https://doi.org/10.1007/978-3-322-98830-0that many carcinogens are not detected in this test. Some of these “false negative” compounds, such as highly chlorinated organic carcinogens, are also difficult to detect in other mutagenicity assays. Dimethylnitrosamine (DMN), however, is negative in the standard . plate incorporation assay,. alth作者: EPT 時間: 2025-3-26 05:51 作者: Anthropoid 時間: 2025-3-26 10:17
J. Wenzel (Oberregierungs- und -gewerberat)wing interest in the biological activity of this group of compounds. Extensive studies of the carcinogenic activity of N-nitroso compounds of various structures have been carried out with the aim of using the differences in activity to suggest possible mechanisms of their carcinogenic action. This a作者: LATER 時間: 2025-3-26 14:22
https://doi.org/10.1007/978-3-662-34626-6d as prescreens for detecting carcinogens. These assays measure a wide spectrum of genetic damage such as gene mutations, DNA repair synthesis, chromatid or chromosomal abberations, and certain physiological or structural changes. The philosophy of using short-term assays and the merits and limitati作者: 退潮 時間: 2025-3-26 18:53 作者: sorbitol 時間: 2025-3-26 23:44
https://doi.org/10.1007/978-3-658-00293-0oon after the Ames test began to gain worldwide acceptance showed that nitrosamines, as a chemical class, did not demonstrate a consistent correlation between mutagenicity and carcinogenicity.. However, the more this testing was used, the more information was uncovered that showed the flexibility and adaptability of the assay.作者: 飛行員 時間: 2025-3-27 03:50
https://doi.org/10.1007/978-3-662-26342-6, tobacco products, and also at the work place in industry. The first report by Magee and Barnes. nearly 25 years ago that nitrosodimethylamine (NDMA) caused tumors in experimental animals initiated an unbounded interest among researchers throughout the world to assess the biological hazard caused by these compounds.作者: 辭職 時間: 2025-3-27 07:00
Formation of N-Nitroso Compounds and Their Significance,e adverse biological effects until 1937, when a case of poisoning by N-nitrosodimethylamine was reported but largely ignored.. A detailed investigation of the toxicity of nitrosodimethylamine began in England in the 1950s as a result of another accidental poisoning, the first results being reported by Barnes and Magee in 1954..作者: Sciatica 時間: 2025-3-27 11:22
N-Nitrosamine Mutagenicity Using the ,/Mammalian-Microsome Mutagenicity Assay,oon after the Ames test began to gain worldwide acceptance showed that nitrosamines, as a chemical class, did not demonstrate a consistent correlation between mutagenicity and carcinogenicity.. However, the more this testing was used, the more information was uncovered that showed the flexibility and adaptability of the assay.作者: 熱烈的歡迎 時間: 2025-3-27 14:21 作者: nominal 時間: 2025-3-27 18:58 作者: 低三下四之人 時間: 2025-3-28 01:13
https://doi.org/10.1007/978-1-4684-4595-4Mamma; Salmonella; cancer; environment; mutagenesis; pesticide; toxicology; xenobiotic作者: antidote 時間: 2025-3-28 05:08 作者: 同義聯(lián)想法 時間: 2025-3-28 08:50 作者: 終點 時間: 2025-3-28 10:44
Structural Basis for Mutagenic Activity of N-Nitrosamines in the , Histidine Reversion Assay,, tobacco products, and also at the work place in industry. The first report by Magee and Barnes. nearly 25 years ago that nitrosodimethylamine (NDMA) caused tumors in experimental animals initiated an unbounded interest among researchers throughout the world to assess the biological hazard caused b作者: HUMP 時間: 2025-3-28 15:56
Effects of pH and Structure on the Mutagenic Activity of N-Nitroso Compounds, practical interest to researchers for a number of reasons, such as their organo-tropic tumor induction, the large variability in the potencies and target organs of various N-nitroso compounds, the relatively simple metabolism and breakdown of the lower molecular weight compounds, and the fact that 作者: Needlework 時間: 2025-3-28 19:02 作者: voluble 時間: 2025-3-28 23:42 作者: 火光在搖曳 時間: 2025-3-29 06:43
Dimethylnitrosamine Demethylase and the Mutagenicity of Dimethylnitrosamine,that many carcinogens are not detected in this test. Some of these “false negative” compounds, such as highly chlorinated organic carcinogens, are also difficult to detect in other mutagenicity assays. Dimethylnitrosamine (DMN), however, is negative in the standard . plate incorporation assay,. alth作者: extrovert 時間: 2025-3-29 09:19 作者: nonplus 時間: 2025-3-29 11:23 作者: 合適 時間: 2025-3-29 18:00 作者: FIG 時間: 2025-3-29 23:15
trophes be avoided? How can we insure the progress and security of coming generations? TRIZ teaches us how to make inventions! TRIZ teaches us how to construct the future! TRIZ changes your thinking, i.e., all of civilization, too! Rational decisions about the problems above cannot be made today wit作者: 思考才皺眉 時間: 2025-3-30 01:08
Energiemethoden der Elastostatik,ate residues are found primarily on the outer surface of the plasma membrane or in the extracellular space. Their expression is cell or tissue specific and developmentally regulated. Due to their structural diversity, they play important roles in a variety of biological processes such as membrane transport and cell–cell interactions.
