作者: 芭蕾舞女演員 時間: 2025-3-21 20:56
https://doi.org/10.1007/978-3-658-25767-5velopment. In other disease states, research is only just beginning to identify genetic loci that could be responsible for development. This chapter is meant to answer the following question: how much of our health can we control, and what role does genetic variation play in disease development?作者: 宣傳 時間: 2025-3-22 03:52 作者: crescendo 時間: 2025-3-22 05:14
https://doi.org/10.1007/978-3-662-29106-1can vary greatly in their levels of expression, protein folding, membrane localization, and transporter efficiencies [3, 13]. These phenotypic differences can ultimately result in major interindividual variabilities in response to identical drug molecules (i.e., pharmacokinetics (PK), pharmacodynami作者: LATHE 時間: 2025-3-22 09:37 作者: nautical 時間: 2025-3-22 14:03 作者: nautical 時間: 2025-3-22 17:29
https://doi.org/10.1007/978-3-662-26353-2beling describing risk for adverse drug events, genotype-specific dosing, and/or variations in pharmacokinetic and pharmacodynamic parameters. For a select group of medications, such as codeine and clopidogrel, pharmacogenomic information may even be highlighted in a black box warning further emphas作者: foliage 時間: 2025-3-22 22:37
https://doi.org/10.1007/978-3-658-25380-6associated with variability in drug response. This review focuses on the genetic polymorphisms of phases I and II DMEs and their associations with drug responses. The drugs discussed in this review requiring a pharmacogenomic test before being prescribed includes efavirenz, voriconazole, clopidogrel作者: 無底 時間: 2025-3-23 05:12
Die Ausrüstung der textilen Warenal pollutants, where the World Health Organization (WHO) now uses the term “environmental burden of disease” to describe adverse effects of a man-made climate, ecosystem degradation, cumulative rise in pollutants, noise, and electromagnetic fields, etc. While epigenetic environmental triggers can al作者: Inculcate 時間: 2025-3-23 08:39
Curt Heidermanns,Inge Kirchner-Kühnt these mutations. In this chapter, Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) are discussed in detail for their pathophysiology, etiology, and latest symptomatic and preventive treatment. In preventive treatment, the latest作者: 遺棄 時間: 2025-3-23 09:48 作者: dapper 時間: 2025-3-23 16:25
Die Aussichten von Zwanglaufkesseln with mastectomy and axillary dissection. The development of pharmacologic hormonal therapy, more effective cytotoxic chemotherapy, and targeted HER2 therapy has improved survival for women with the most common types of breast cancer as well as less common but highly aggressive cancers. The developm作者: Introduction 時間: 2025-3-23 21:38 作者: Camouflage 時間: 2025-3-23 23:28 作者: 粘連 時間: 2025-3-24 02:31
Living Between Sickness and Health: Where Is the Human Genome Leading Us?,velopment. In other disease states, research is only just beginning to identify genetic loci that could be responsible for development. This chapter is meant to answer the following question: how much of our health can we control, and what role does genetic variation play in disease development?作者: foreign 時間: 2025-3-24 06:58
The Food Metabolome and Novel Dietary Biomarkers Associated with Diseases,nsion, and diabetes. Contrasting this is the “prudent” dietary pattern characterized by increased fruit, vegetables, poultry, fish, whole grains, and legumes which had improved biomarker profiles of the aforementioned diseases. Similar to the “Western” pattern is a diet with . saturated fat/high sim作者: glucagon 時間: 2025-3-24 14:27 作者: 失望未來 時間: 2025-3-24 16:05 作者: Hot-Flash 時間: 2025-3-24 19:40
Essentials of Genomics in the Continuum of Translational Research,y which new research discoveries are translated into clinical and useful genomic testing so that a framework for personalized medicine can be developed. This chapter focuses mainly on the continuum of an evidence-based framework for multidisciplinary translational research in genomics along with sev作者: Ingredient 時間: 2025-3-25 01:45
Charting a Course for Genomic Medicine from Base Pair to Bedside,beling describing risk for adverse drug events, genotype-specific dosing, and/or variations in pharmacokinetic and pharmacodynamic parameters. For a select group of medications, such as codeine and clopidogrel, pharmacogenomic information may even be highlighted in a black box warning further emphas作者: figurine 時間: 2025-3-25 05:37 作者: EXTOL 時間: 2025-3-25 08:17
Epigenetic Patterns/Therapies Associated with Genetic Disorders,al pollutants, where the World Health Organization (WHO) now uses the term “environmental burden of disease” to describe adverse effects of a man-made climate, ecosystem degradation, cumulative rise in pollutants, noise, and electromagnetic fields, etc. While epigenetic environmental triggers can al作者: IRK 時間: 2025-3-25 14:55 作者: 逃避現(xiàn)實 時間: 2025-3-25 18:23
Recent Trends in -Omics-Based Methods and Techniques for Lung Disease Prevention,done on chemicals that are in use in manufacturing [2]. With the use of toxicogenomics, there is the ability to determine the level of toxicity that is associated with certain properties of ENMs as well as assist in the identification of potential health hazards [2, 3]. DNA microarray, large-scale r作者: encyclopedia 時間: 2025-3-25 21:15 作者: cardiac-arrest 時間: 2025-3-26 00:16
Book 2018base with utility in preventing and treating disease, and improving health for all. Bioinformatics and improved pharmacogenetic understanding forge a path for improved drug discovery and design methods accounting for differences in delivery and disposition across populations..作者: 確認(rèn) 時間: 2025-3-26 04:49 作者: resuscitation 時間: 2025-3-26 11:55
,Entlastung der Fürsorgearbeit,ies to abate drug attrition at later stages of drug development as illustrated by numerous drug examples. Lessons learned from these drug development studies are then applied to product labeling and the post-marketing comprehension of drug behavior.作者: cognizant 時間: 2025-3-26 13:39
Race and Ethnicity: Understanding Difference in the Genome Era,ied race encourages neglect of important environmental factors. Race-based pharmaceuticals reify biological difference while creating a niche market. Attempts to regulate the use of race in genomics research promise future scholarly debate on the roles of race and ethnicity in genetics.作者: floodgate 時間: 2025-3-26 17:03 作者: 染色體 時間: 2025-3-26 23:31 作者: packet 時間: 2025-3-27 03:11
https://doi.org/10.1007/978-3-322-98660-3nd surveillance researches provided useful clues to reduce the impact of spread of infectious diseases worldwide. Many studies, associated with population science in disease control, help in many ways to control the infectious diseases, such as:作者: 死亡率 時間: 2025-3-27 07:47 作者: 惰性氣體 時間: 2025-3-27 11:02
Bioinformatics and Pharmacogenomics: Tools to Understand and Accelerate Infectious Disease Control,nd surveillance researches provided useful clues to reduce the impact of spread of infectious diseases worldwide. Many studies, associated with population science in disease control, help in many ways to control the infectious diseases, such as:作者: 切割 時間: 2025-3-27 15:22
Pharmacogenomics: A New Approach for Preventing Severe Cutaneous Adverse Drug Reactions,of drug-induced SCARs is discussed. Drugs associated with hypersensitivity reactions with strong genetic predisposing factors include abacavir, nevirapine, carbamazepine, allopurinol, etc. The gaps, unmet needs, and priorities for future research are identified in order to eliminate genetically mediated SCARs globally.作者: 吹牛者 時間: 2025-3-27 20:00 作者: intimate 時間: 2025-3-28 00:04
https://doi.org/10.1007/978-3-663-04598-4 one-time pharmacogenomic testing for asymptomatic patients was shown to be cost-effective to minimize lifetime ADRs for a given age group [2]. This should stimulate and encourage preemptive genotyping especially with the recent advances and cost reduction in genomic sequencing technologies.作者: 最高峰 時間: 2025-3-28 03:07
Pharmacogenomics: Setting Newer Paradigms of Genetics in Therapy and Medicine,e possibility of toxicities of specific drugs in patients and, consequently, assist in the modification of therapy for such patients to improve clinical outcome. In this chapter, we study the current status of pharmacogenomics and its future prospects of how it will impact the current clinical practices for better therapy.作者: 大洪水 時間: 2025-3-28 08:01 作者: Platelet 時間: 2025-3-28 12:45
mics in disease and disease prevention.Provides understandin.This book evaluates trends arising in “-Omics” sciences in terms of their current and potential future application to therapeutic design and understanding of disease. Chapters consider the impact of pharmacogenomics and bioinformatics on d作者: genesis 時間: 2025-3-28 18:03 作者: 課程 時間: 2025-3-28 19:26
Living Between Sickness and Health: Where Is the Human Genome Leading Us?,ucleotide polymorphisms. These SNPs account for much of the variance between people; therefore, it makes sense that the SNPs could also reveal the variance in health between people. This chapter delves into common diseases that appear later in life and potential genetic risk factors for the diseases作者: Recess 時間: 2025-3-28 23:14
Pharmacogenomics: Setting Newer Paradigms of Genetics in Therapy and Medicine,ics provides a tool to determine the genetic makeup of individuals and help in establishing relevant genotype-phenotype correlation. This knowledge may uncover the predisposition of patients toward specific disease conditions like diabetes and cardiovascular diseases. It can also be used to gauge th作者: Reservation 時間: 2025-3-29 03:16
Bioinformatics and Pharmacogenomics: Tools to Understand and Accelerate Infectious Disease Control,and bacterial infections, on the population [1–3]. Timely information on these diseases aids in reducing risk, incidence and deaths associated with these diseases. It also helps to improve the quality of life for survivors. These research projects provided a common platform for clinical, basic and p作者: Excitotoxin 時間: 2025-3-29 08:47 作者: Dissonance 時間: 2025-3-29 14:00
The Food Metabolome and Novel Dietary Biomarkers Associated with Diseases,apter will review and assess the current literature of the novel biomarkers used to track dietary intake of carbohydrates, fats, proteins, vitamin C, and carotenoids, as well as to explore the relationship between dietary patterns and biomarkers associated with disease processes. There is good evide作者: Melanocytes 時間: 2025-3-29 17:51 作者: 作嘔 時間: 2025-3-29 21:40 作者: 取回 時間: 2025-3-30 03:11
Genomics and Drug-Metabolizing Enzymes and Its Application in Drug Delivery: Evaluating the Influen an assorted group of enzymes responsible for metabolizing xenobiotics such as drugs, carcinogens, pesticides, and food toxicants as well as endogenous compounds such as prostaglandins, steroids, and bile acids [2, 3]. R.T. Williams coined the concept of two-phase elimination of xenobiotics; reactio作者: 中古 時間: 2025-3-30 07:18
Essentials of Genomics in the Continuum of Translational Research, to develop comprehensive research guidelines so that human genome discoveries can be translated into health practice. This should be done in a way that maximizes health benefits and minimizes harm to individuals and populations..Genomic testing is used in predicting the risk of certain diseases. It作者: 完整 時間: 2025-3-30 11:11 作者: Chronological 時間: 2025-3-30 15:09 作者: Pigeon 時間: 2025-3-30 18:18 作者: 天空 時間: 2025-3-30 20:50 作者: 發(fā)芽 時間: 2025-3-31 04:49
Neurodegenerative Disease Conditions and Genomic Treatment for Better Health,y of central or peripheral nervous. The neurodegenerative diseases (NDs) like Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) are responsible for more than 1% deaths and more than 2% disabilities of total world population. These 作者: NATTY 時間: 2025-3-31 07:10 作者: 能得到 時間: 2025-3-31 10:21
Impact of Genomics on Personalization of Breast Cancer Care,mized prospective clinical trials in 1959, a novel concept at the time, by the National Surgical Adjuvant Breast and Bowel Project (NSABP) under the guidance of Bernard Fisher established a scientific philosophy as the guiding force in breast cancer treatment. Since 1975, multiple innovations have i作者: Inelasticity 時間: 2025-3-31 16:10 作者: 釘牢 時間: 2025-3-31 21:00
