標題: Titlebook: Genomic Mosaicism in Neurons and Other Cell Types; José María Frade,Fred H. Gage Book 2017 Springer Science+Business Media LLC 2017 FISH.n [打印本頁] 作者: 壓榨機 時間: 2025-3-21 16:32
書目名稱Genomic Mosaicism in Neurons and Other Cell Types影響因子(影響力)
書目名稱Genomic Mosaicism in Neurons and Other Cell Types影響因子(影響力)學(xué)科排名
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書目名稱Genomic Mosaicism in Neurons and Other Cell Types網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Genomic Mosaicism in Neurons and Other Cell Types被引頻次
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書目名稱Genomic Mosaicism in Neurons and Other Cell Types讀者反饋
書目名稱Genomic Mosaicism in Neurons and Other Cell Types讀者反饋學(xué)科排名
作者: Debility 時間: 2025-3-21 21:56 作者: Cleave 時間: 2025-3-22 02:01 作者: placebo 時間: 2025-3-22 06:05
Giant Cell Reparative Granulomation, some populations of vertebrate neurons can also show double the normal amount of DNA, a condition referred to as somatic tetraploidy. These neurons are generated during early stages of development, as they migrate to their adult locations in the adult nervous system, and constitute subpopulati作者: 品牌 時間: 2025-3-22 09:14
Poor-Prognosis Germ Cell Tumoursution of neurons with DNA content variation (DCV) in the context of preserved tissue architecture. The method had been optimized for DNA quantification of identified neurons but could easily be adapted to other tissues. It had been validated against chromogenic in situ hybridization (CISH) with chro作者: Simulate 時間: 2025-3-22 14:28
Steven P. Rowe,Yafu Yin,Michael A. Gorins to isolate neuronal nuclei from human brain and identify megabase-scale copy number variants (CNVs) in single nuclei. The approach detailed herein includes use of CellRaft technology for single-nucleus isolation, the PicoPLEX approach to whole-genome amplification and library preparation, and a po作者: Simulate 時間: 2025-3-22 19:23
R. Curtis Ellison,Peter F. Cohned to examine the genome at single-cell resolution. Here we describe the recent progress in the development of single-cell whole-genome amplification methods and the state of art for analyzing one of the major forms of genomic variations—copy number of variations (CNVs). Robust detection of CNVs in 作者: exclamation 時間: 2025-3-22 22:51
G. Schley,W. Hengstebeck,K. D. Bockwn to cause particular neurodegenerative diseases. We developed a dNTP-limited, competitive PCR technique to identify relative copy number differences between a reference and one or more target genes. Suitable fragments with single melting domains, well-separated melting temperatures, and no common 作者: BILK 時間: 2025-3-23 02:48 作者: Arrhythmia 時間: 2025-3-23 06:28 作者: 終點 時間: 2025-3-23 09:56 作者: Insulin 時間: 2025-3-23 15:35 作者: Spirometry 時間: 2025-3-23 21:27
Sexual Dysfunction in Neurological Disease,us mechanisms including errors in DNA replication acquired throughout development and by the activity of endogenous retrotransposons. The study of retrotransposition in neuronal mosaicism may prove crucial to understanding the true complexity of normal and aberrant brain function. Specifically, nume作者: Offensive 時間: 2025-3-23 22:28
https://doi.org/10.1007/978-3-642-46172-9ated as a main causal factor in aging. The most severe form of genomic instability is whole chromosome instability (W-CIN), a state where dysfunction in chromosome segregation leads to whole chromosomes gains and losses. Aneuploidy is commonly linked to pathological states. It is a hallmark of spont作者: 不容置疑 時間: 2025-3-24 04:31 作者: 聯(lián)想 時間: 2025-3-24 07:54
https://doi.org/10.1007/978-1-4939-7280-7FISH; neuronal aneuploidy; Flow cytometric; cytometry; somatic L1 insertions作者: Frenetic 時間: 2025-3-24 11:47 作者: monologue 時間: 2025-3-24 16:44 作者: Abduct 時間: 2025-3-24 20:18
Book 2017ul results in your laboratory..Cutting-edge and authoritative, .Genomic Mosaicism in Neurons and Other Cell Types. is a valuable resource for learning about the latest techniques for the analysis of genome and genetic mosaicism in vertebrate neurons..作者: 轉(zhuǎn)折點 時間: 2025-3-25 00:45 作者: 心神不寧 時間: 2025-3-25 03:20 作者: orient 時間: 2025-3-25 08:53 作者: 背景 時間: 2025-3-25 14:46
Estimation of LINE-1 Copy Number in the Brain Tissue and Isolated Neuronal NucleiLINE-1 copies. In this chapter, we describe practical methods for isolating neuronal nuclei from frozen brain tissue and cultured cells, extracting genomic DNA, and estimating LINE-1 copy numbers with quantitative reverse transcription-polymerase chain reactions.作者: 傻 時間: 2025-3-25 18:07 作者: Myofibrils 時間: 2025-3-25 22:27 作者: 否認 時間: 2025-3-26 02:27 作者: legislate 時間: 2025-3-26 05:03 作者: cumber 時間: 2025-3-26 09:03 作者: prosthesis 時間: 2025-3-26 14:39 作者: 造反,叛亂 時間: 2025-3-26 18:53 作者: macabre 時間: 2025-3-26 21:58 作者: NUDGE 時間: 2025-3-27 02:27 作者: 血統(tǒng) 時間: 2025-3-27 07:34 作者: 表兩個 時間: 2025-3-27 11:46 作者: 有角 時間: 2025-3-27 13:55 作者: Transfusion 時間: 2025-3-27 18:42 作者: Substance-Abuse 時間: 2025-3-27 22:47
FISH-Based Assays for Detecting Genomic (Chromosomal) Mosaicism in Human Brain Cellsever, there is still a lack of consensus concerning the extent and effects of mosaic chromosome abnormalities (i.e., aneuploidy) in the normal and diseased human brain. To solve this problem, a need for detailed description of single-cell techniques for chromosomal analysis of human brain cells appe作者: 陰郁 時間: 2025-3-28 02:35 作者: Gullible 時間: 2025-3-28 06:53 作者: Paradox 時間: 2025-3-28 12:55 作者: 依法逮捕 時間: 2025-3-28 15:00
Single-Cell CNV Detection in Human Neuronal Nucleis to isolate neuronal nuclei from human brain and identify megabase-scale copy number variants (CNVs) in single nuclei. The approach detailed herein includes use of CellRaft technology for single-nucleus isolation, the PicoPLEX approach to whole-genome amplification and library preparation, and a po作者: ingenue 時間: 2025-3-28 20:18 作者: insidious 時間: 2025-3-29 01:22 作者: 參考書目 時間: 2025-3-29 04:23 作者: BOGUS 時間: 2025-3-29 07:24
Analysis of LINE-1 Retrotransposition in Neural Progenitor Cells and Neuronssuggested that L1 activity, termed as L1 retrotransposition, may occur in somatic cells such as neural progenitor cells (NPC) in higher rate than other non-brain tissues. Indeed, L1 retrotransposition has been found to be associated with several types of neurological disorders. Thus, L1 activity may作者: Spina-Bifida 時間: 2025-3-29 14:17
Estimation of LINE-1 Copy Number in the Brain Tissue and Isolated Neuronal Nucleispersed element-1 (LINE-1) retrotranspositions are usually rare, the targeting of specific brain cell types in genomic analyses of these mutations is critical. We previously reported that isolated neuronal nuclei from the prefrontal cortex of patients with schizophrenia exhibit increased numbers of 作者: Esalate 時間: 2025-3-29 19:06 作者: FLOUR 時間: 2025-3-29 23:04
Single-Cell Whole Genome Amplification and Sequencing to Study Neuronal Mosaicism and Diversityus mechanisms including errors in DNA replication acquired throughout development and by the activity of endogenous retrotransposons. The study of retrotransposition in neuronal mosaicism may prove crucial to understanding the true complexity of normal and aberrant brain function. Specifically, nume作者: 調(diào)整 時間: 2025-3-30 01:31
FISH Analysis of Aging-Associated Aneuploidy in Neurons and Nonneuronal Brain Cellsated as a main causal factor in aging. The most severe form of genomic instability is whole chromosome instability (W-CIN), a state where dysfunction in chromosome segregation leads to whole chromosomes gains and losses. Aneuploidy is commonly linked to pathological states. It is a hallmark of spont作者: NEG 時間: 2025-3-30 07:50 作者: Reservation 時間: 2025-3-30 09:02
Psychological Issues and Their Treatmentpopulation-specific FANS (also see chapter “Single-Cell Whole Genome Amplification and Sequencing to Study Neuronal Mosaicism and Diversity”) in downstream analyses such as fluorescent in situ hybridization (.) (see chapters “FISH-Based Assays for Detecting Genomic (Chromosomal) Mosaicism in Human B作者: 打算 時間: 2025-3-30 13:21
Giant Cell Reparative Granulomather analyses, either used directly or after whole-genome amplification. Here we show as an example how to perform epigenetic analyses to characterize CpG methylation in differentially methylated regions controlling the .imprinting domain?in mice.作者: conscribe 時間: 2025-3-30 18:17
Poor-Prognosis Germ Cell Tumourslar biological characterization of single microscopically identified neurons as outlined here might be a promising approach to study molecular individuality of neurons in the context of its physiological or pathophysiological environment. It reflects the concept of cytomics and will forward our unde作者: Acetabulum 時間: 2025-3-31 00:22 作者: Arthropathy 時間: 2025-3-31 03:57
Diagnostic Systems and Their Use, genome-wide mutation detection. This approach allows the detection of false positives due to amplification artifacts and is applicable to all classes of mutations. While it is both sensitive and reliable, our method is lower throughput than single-cell sequencing-based approaches and may also fail
