標(biāo)題: Titlebook: Genome Stability and Human Diseases; Heinz-Peter Nasheuer Book 2010 Springer Science+Business Media B.V. 2010 Chromosom.DNA.Viruses.genes. [打印本頁] 作者: SCOWL 時(shí)間: 2025-3-21 18:36
書目名稱Genome Stability and Human Diseases影響因子(影響力)
書目名稱Genome Stability and Human Diseases影響因子(影響力)學(xué)科排名
書目名稱Genome Stability and Human Diseases網(wǎng)絡(luò)公開度
書目名稱Genome Stability and Human Diseases網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Genome Stability and Human Diseases被引頻次
書目名稱Genome Stability and Human Diseases被引頻次學(xué)科排名
書目名稱Genome Stability and Human Diseases年度引用
書目名稱Genome Stability and Human Diseases年度引用學(xué)科排名
書目名稱Genome Stability and Human Diseases讀者反饋
書目名稱Genome Stability and Human Diseases讀者反饋學(xué)科排名
作者: Deference 時(shí)間: 2025-3-21 22:18
Deutsches Krebsforschungszentrum Heidelberguired for resumption of cell proliferation after DNA repair. Emerging evidence, although not without conflict, suggests that H3K56ac is not only present in human cells, but is similarly regulated and required for chromatin reassembly.作者: fructose 時(shí)間: 2025-3-22 03:49 作者: 不在灌木叢中 時(shí)間: 2025-3-22 05:28 作者: TAP 時(shí)間: 2025-3-22 12:41 作者: 染色體 時(shí)間: 2025-3-22 13:35 作者: 染色體 時(shí)間: 2025-3-22 17:22 作者: Conscientious 時(shí)間: 2025-3-22 23:08
DNA Polymerases and Mutagenesis in Human Cancers,rror prone repair of some kind of lesions by alternatives routes, thus leading to accumulation of mutations and contributing to genomic instability, a common feature of cancer cell. In this chapter, we present the role of each Pol in genome maintenance and highlight the connections between the malfunctioning of these enzymes and cancer progress.作者: 戰(zhàn)役 時(shí)間: 2025-3-23 05:04
Fluorescence-Based Quantification of Pathway-Specific DNA Double-Strand Break Repair Activities: A nce the proteins of interest frequently have dual roles in DSB repair surveillance and checkpoint control, our assay procedure concomitantly corrects for transfection efficiencies, growth-, death-, and expression-related changes and also integrates the examination of the cell cycle status.作者: HAIL 時(shí)間: 2025-3-23 08:46 作者: 狂熱文化 時(shí)間: 2025-3-23 12:11 作者: 喚起 時(shí)間: 2025-3-23 15:45
Deutsches Verfassungsrecht 1806 - 1918maged cells is fundamental in maintaining the health of organisms. In addition, apoptosis induction following DNA damage is exploited to kill cancer cells. In this chapter we will review the main features of developmental and induced apoptosis.作者: Statins 時(shí)間: 2025-3-23 18:37 作者: 黑豹 時(shí)間: 2025-3-23 22:53 作者: 根除 時(shí)間: 2025-3-24 03:19
Deutsches Meteorologisches Jahrbuch 193826T RNA in somatic macronuclei of the ciliate . and G-rich RNA in the Epstein-Barr DNA tumour virus and its human host cells. Here, I will give an overview of the experimental evidence in favour of roles for these non-coding RNAs in the regulation of eukaryotic DNA replication, and compare and contrast their biosynthesis and mechanisms of action.作者: Fatten 時(shí)間: 2025-3-24 08:06
Non-coding RNAs: New Players in the Field of Eukaryotic DNA Replication,26T RNA in somatic macronuclei of the ciliate . and G-rich RNA in the Epstein-Barr DNA tumour virus and its human host cells. Here, I will give an overview of the experimental evidence in favour of roles for these non-coding RNAs in the regulation of eukaryotic DNA replication, and compare and contrast their biosynthesis and mechanisms of action.作者: Host142 時(shí)間: 2025-3-24 13:43 作者: 額外的事 時(shí)間: 2025-3-24 15:09 作者: 江湖騙子 時(shí)間: 2025-3-24 20:53
Heinz-Peter NasheuerDiscusses cancer cell biology in relation to Genome stability and Cell cycle regulation.Unique assembly of experts in these fields who wrote a comprehensive and deep up-to-date overview.Discusses mode作者: 有限 時(shí)間: 2025-3-25 01:20 作者: CLAM 時(shí)間: 2025-3-25 05:47
,Einige Regeln für Anfragen auf Krane,rring processes such as DNA replication and recombination can result in DNA double-strand breaks (DSBs). DSBs are potentially lethal and so eukaryotic cells have evolved an elaborate pathway, the DNA damage response, which detects the damage, recruits proteins to the DSBs, activates checkpoints to s作者: FLAIL 時(shí)間: 2025-3-25 08:53
Deutsches Krebsforschungszentrum Heidelberg are frequently post-translational modified. Such covalent additions to histone residues can modulate chromatin folding and/or provide specificity to docking surfaces for non-histone chromatin proteins. In the budding yeast, one such modification, transient acetylation of histone H3 on residue lysin作者: BARK 時(shí)間: 2025-3-25 13:02
Wirtschaftliches; Speise und Trankg of DNA damage events and by acting as a foundation for the assembly of repair foci. The H2AX protein sequence is highly similar and in some cases overlapping with replication-dependent canonical H2A, yet the H2AX gene and protein structures exhibit a number of features specific to the role of this作者: 阻撓 時(shí)間: 2025-3-25 18:44 作者: 騷動(dòng) 時(shí)間: 2025-3-25 20:09 作者: 看法等 時(shí)間: 2025-3-26 02:33 作者: A簡(jiǎn)潔的 時(shí)間: 2025-3-26 07:58 作者: 忍耐 時(shí)間: 2025-3-26 10:25 作者: 吞噬 時(shí)間: 2025-3-26 15:59 作者: Chameleon 時(shí)間: 2025-3-26 19:40
https://doi.org/10.1007/978-3-662-69378-0and the origin of these mutations and how replication proteins modulate this process. DNA polymerase γ (pol γ) is the polymerase that is responsible for replication and repair of mtDNA. Pol γ has three main roles in mtDNA maintenance and mutagenesis. As the only known DNA polymerase in mitochondria,作者: cuticle 時(shí)間: 2025-3-26 23:36
Deutsches Reichs- und Landesstaatsrechtomic stability. This chapter will describe the structure and assembly of an epigenetically inherited locus, the centromere, and its role in the processes by which sister chromatids are evenly segregated to daughter cells. During the G2 phase of the cell cycle kinetochores are assembled upon the chro作者: extinguish 時(shí)間: 2025-3-27 03:43 作者: SPER 時(shí)間: 2025-3-27 06:54
Deutsches Verfassungsrecht 1806 - 1918tive metabolism, ionizing radiation, and inadvertent action by enzymes of DNA metabolism (such as failures of type II topoisomerases or cleavage by recombinases at off-target sites). There are two major double-strand break repair pathways. Homologous recombination (HR) can repair double-strand break作者: white-matter 時(shí)間: 2025-3-27 10:08 作者: 打谷工具 時(shí)間: 2025-3-27 13:45 作者: Ceremony 時(shí)間: 2025-3-27 21:46 作者: 小平面 時(shí)間: 2025-3-28 01:10 作者: BILIO 時(shí)間: 2025-3-28 05:33 作者: mosque 時(shí)間: 2025-3-28 08:37
Book 2010isition of somatic mutations...This book is written by international leading scientists in the field of genome stability. Chapters are devoted to genome stability and anti-cancer drug targets, histone modifications, chromatin factors, DNA repair, apoptosis and many other key areas of research. The c作者: 來自于 時(shí)間: 2025-3-28 11:36
https://doi.org/10.1007/978-3-642-48569-5moved by gene deletion or depleted by RNA interference. That those situations in no way resemble ones in which CDKs are inhibited pharmacologically is often overlooked or downplayed. A more nuanced – and accurate – picture is now coming into view, thanks to recent studies that reveal kinetically dis作者: 有助于 時(shí)間: 2025-3-28 16:38
,Einige Regeln für Anfragen auf Krane, as such, are particularly important in the early stages of the DNA damage response. This review will focus on such modifications, the enzymes responsible and also highlights their importance by reporting known roles for these modifications in genome stability and disease.作者: 機(jī)制 時(shí)間: 2025-3-28 19:40
Wirtschaftliches; Speise und Trank Furthermore, the biochemical properties of H2AX protein within the nucleosome structure and its distribution within chromatin also point to features linked to its role in the DNA damage response. In particular, the theoretical inter-nucleosomal spacing of H2AX and the potential implications of amin作者: ACTIN 時(shí)間: 2025-3-29 00:12 作者: debris 時(shí)間: 2025-3-29 07:05 作者: 賞心悅目 時(shí)間: 2025-3-29 11:14
Heidelberger Akademie der Wissenschaftene TLS at sites of UV-induced dithymine CPDs. The active site of Pol η has an open conformation that can accommodate CPDs, as well as cisplatin-induced intrastrand DNA crosslinks. Pol η is recruited to sites of replication arrest in a tightly regulated process through interaction with PCNA. Pol η-def作者: incite 時(shí)間: 2025-3-29 15:15
Deutsches Reichs- und Landesstaatsrechtd centromeres themselves are determined by their unique protein composition. Apart from budding yeast, centromeres are not specified simply by DNA sequence, but rather through chromatin composition and architecture and are thus epigenetically determined. Centromeres are built on a specific nucleosom作者: 線 時(shí)間: 2025-3-29 17:50 作者: 全部 時(shí)間: 2025-3-29 23:26 作者: 白楊 時(shí)間: 2025-3-30 01:41 作者: 反饋 時(shí)間: 2025-3-30 08:02 作者: ENNUI 時(shí)間: 2025-3-30 08:52
Core and Linker Histone Modifications Involved in the DNA Damage Response, as such, are particularly important in the early stages of the DNA damage response. This review will focus on such modifications, the enzymes responsible and also highlights their importance by reporting known roles for these modifications in genome stability and disease.作者: 可行 時(shí)間: 2025-3-30 16:21
Structure and Function of Histone H2AX, Furthermore, the biochemical properties of H2AX protein within the nucleosome structure and its distribution within chromatin also point to features linked to its role in the DNA damage response. In particular, the theoretical inter-nucleosomal spacing of H2AX and the potential implications of amin作者: 領(lǐng)先 時(shí)間: 2025-3-30 18:42 作者: 全能 時(shí)間: 2025-3-31 00:45 作者: 熄滅 時(shí)間: 2025-3-31 04:52 作者: Nutrient 時(shí)間: 2025-3-31 07:21
Centromeres: Assembling and Propagating Epigenetic Function,d centromeres themselves are determined by their unique protein composition. Apart from budding yeast, centromeres are not specified simply by DNA sequence, but rather through chromatin composition and architecture and are thus epigenetically determined. Centromeres are built on a specific nucleosom作者: 攝取 時(shí)間: 2025-3-31 11:54 作者: 記憶 時(shí)間: 2025-3-31 17:18
Nonhomologous DNA End Joining (NHEJ) and Chromosomal Translocations in Humans,se μ (Pol μ), DNA polymerase . (Pol .), XLF (also called Cernunnos), XRCC4, and DNA ligase IV. These enzymes constitute what some call the classical NHEJ pathway, and in wild type cells, the vast majority of joining events appear to proceed using these components. NHEJ is present in many prokaryotes作者: Thrombolysis 時(shí)間: 2025-3-31 20:03
