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標(biāo)題: Titlebook: Genome Integrity; Facets and Perspecti Dirk-Henner Lankenau Book 2007 Springer-Verlag Berlin Heidelberg 2007 Chromosom.DNA.DNA Repair.Genet [打印本頁]

作者: satisficer    時間: 2025-3-21 19:51
書目名稱Genome Integrity影響因子(影響力)




書目名稱Genome Integrity影響因子(影響力)學(xué)科排名




書目名稱Genome Integrity網(wǎng)絡(luò)公開度




書目名稱Genome Integrity網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Genome Integrity被引頻次




書目名稱Genome Integrity被引頻次學(xué)科排名




書目名稱Genome Integrity年度引用




書目名稱Genome Integrity年度引用學(xué)科排名




書目名稱Genome Integrity讀者反饋




書目名稱Genome Integrity讀者反饋學(xué)科排名





作者: Exhilarate    時間: 2025-3-21 20:16

作者: 終點    時間: 2025-3-22 03:34
DNA Polymerases and Diseasesalso critically evaluating those cases where the experimental data are not fully convincing. To this aim, we will first give a?short overview of the three main DNA metabolic events, namely replication, repair and recombination, as well as of the checkpoint pathways acting in response to DNA damage.
作者: BRAVE    時間: 2025-3-22 05:14

作者: 虛弱的神經(jīng)    時間: 2025-3-22 09:38
Germline Double-Strand Break Repair and Gene Targeting in ,: A?Trajectory System throughout Evolutio of metazoans. In contrast, most studies concerning DNArepair in mammals focused on somatic cells while only few authors engaged in embryonic stem cells. . represents a?field of in vivo biochemistry systems linking DNArepair research with the power of classical genetics and modern developmental, mol
作者: Presbyopia    時間: 2025-3-22 14:50

作者: Presbyopia    時間: 2025-3-22 20:13
Mechanisms of Non-Homologous DNA End Joining:Aspects of In Vitro Assaysning (NHEJ) is the major pathway of DSB repair.Genetic studies in yeast, human and rodent cell lines displaying increased IR sensitivity and defects inDSB repair have provided insight in the genes involved in NHEJ. These genetic data have been confirmed andcomplemented by in vitro assays which have
作者: 懦夫    時間: 2025-3-23 01:11
Role of p53 in Double-Strand Break Repairdouble-strand break repair. In this review, we summarize datafrom biochemical, cell based and in vivo approaches demonstrating that wild-type p53 restrains excessiveand mutagenic DNA exchange events. Thus, p53 appears to exhibit fidelity control of homologous recombination,and recent evidence also s
作者: 確定方向    時間: 2025-3-23 03:18

作者: 不安    時間: 2025-3-23 06:38

作者: 率直    時間: 2025-3-23 13:14
Inter- and Supramolecular Interactions of Protein Kinase CK2 and their Relevance for Genome Integritctivity, it has been shown that it can undergostoichiometric (non-enzymatic) interactions with other proteins. This interaction is not only limited tothe tetrameric holoenzyme; the individual subunits of CK2, i.e. the catalytic α-subunit and the regulatoryβ-subunit, can also interact by themselves w
作者: Odyssey    時間: 2025-3-23 16:11
Role of Human Topoisomerase I in DNA Repair and Apoptosisption and replication. In 1998, it was found thathtopoI might play another important role in the cellular response to DNA damage -- the so-called htopoIdamage response. Since this initial discovery, many studies have suggested that the htopoI damage responseis involved in DNA repair as well as in ap
作者: 符合你規(guī)定    時間: 2025-3-23 20:32

作者: allude    時間: 2025-3-24 01:43

作者: 使困惑    時間: 2025-3-24 05:35
https://doi.org/10.1007/b104871Chromosom; DNA; DNA Repair; Genetics; Genome Dynamics; Genome Integrity; Replication; Viruses; base; chromoso
作者: Autobiography    時間: 2025-3-24 06:46
Dirk-Henner LankenauFirst book to give a full overview on genome integrity in different species.Spans from microorganisms to humans.Addresses the connection between genome integrity and human disease.Written by an intern
作者: Carcinogen    時間: 2025-3-24 11:04

作者: coagulate    時間: 2025-3-24 17:11
Genome Integrity978-3-540-37531-9Series ISSN 1861-3373 Series E-ISSN 1861-3381
作者: 沒有準(zhǔn)備    時間: 2025-3-24 21:07

作者: Assemble    時間: 2025-3-25 00:12

作者: 陰謀小團(tuán)體    時間: 2025-3-25 04:48

作者: 表示向前    時間: 2025-3-25 10:35
,Wirtschafts- und W?hrungspolitik,plication forks . translesion synthesis at the expense of replicational fidelity, error-free bypass mechanisms are available in all organisms analyzed so far to reinstall replication without corrosive effects on the integrity of the genetic information. Reasonable models for error-free replication r
作者: Infuriate    時間: 2025-3-25 13:54

作者: BRIDE    時間: 2025-3-25 16:51
https://doi.org/10.1007/978-3-663-13573-9re ATPase of the Rad50/SMC protein family. Rad50/SMCproteins possess an ATP-binding cassette ATPase domain and a?strikingly long coiled-coil dimerization/linkerdomain. In conjunction with associated subunits, Rad50/SMC proteins form large molecular rings or tetheringstructures that are well suited t
作者: 不利    時間: 2025-3-25 23:47
Deutsch-israelisches Leadership Developmentning (NHEJ) is the major pathway of DSB repair.Genetic studies in yeast, human and rodent cell lines displaying increased IR sensitivity and defects inDSB repair have provided insight in the genes involved in NHEJ. These genetic data have been confirmed andcomplemented by in vitro assays which have
作者: 做方舟    時間: 2025-3-26 04:12

作者: inchoate    時間: 2025-3-26 06:30
Deutsch-jüdische Kinder- und Jugendliterature of chromatin structure and nuclear architecture inthe outcome of repair has, however, only slowly emerged. Important recent developments in the field comprisethe characterization of passive and active chromatin alterations following DSB induction, the function ofchromatin modifying complexes and c
作者: 竊喜    時間: 2025-3-26 11:00

作者: GIBE    時間: 2025-3-26 13:11

作者: 褻瀆    時間: 2025-3-26 20:28

作者: Androgen    時間: 2025-3-26 23:21
https://doi.org/10.1007/978-3-322-85487-2e instability syndromes have a?greatly increased cancerrisk as a?major symptom. The complexity of the involvement of the underlying genes in the cellularresponse to DNA damage is well illustrated by the disorders Nijmegen Breakage Syndrome (NBS) and Fanconianaemia (FA). These two Mendelian diseases
作者: acrobat    時間: 2025-3-27 01:33
,W?rter zur Einübung der Konsonanten,r responses and transcriptional activation of DNA repair genesfollowing exposure of mammalian cells to genotoxic stress. Functional consequences of induction of DNArepair genes are also briefly discussed.
作者: obsession    時間: 2025-3-27 07:50

作者: 制造    時間: 2025-3-27 10:18

作者: 貪婪地吃    時間: 2025-3-27 13:36

作者: AMOR    時間: 2025-3-27 18:04
Induction of DNA Repair Genes in Mammalian Cells in Response to Genotoxic Stressr responses and transcriptional activation of DNA repair genesfollowing exposure of mammalian cells to genotoxic stress. Functional consequences of induction of DNArepair genes are also briefly discussed.
作者: nutrition    時間: 2025-3-28 01:41
Germline Double-Strand Break Repair and Gene Targeting in ,: A?Trajectory System throughout Evolutioxemplified here, recombination tract data reflectthe relatedness of the DSB repair mechanics of SDSA, Break Induced Replication (BIR), Single Strand Annealing(SSA), and the involvement of Holliday junctions (HJs) and non-DSB repair pathways.
作者: 平庸的人或物    時間: 2025-3-28 04:10

作者: BOLT    時間: 2025-3-28 07:49

作者: 盲信者    時間: 2025-3-28 11:07

作者: BACLE    時間: 2025-3-28 17:00
Role of Human Topoisomerase I in DNA Repair and Apoptosismage response is activated. Althoughthe htopoI damage response was discovered several years ago, research in this area is just beginning. Thefuture will surely bring more clarity regarding the precise mechanism behind the involvement of htopoI inDNA repair and apoptosis, as well as its implications
作者: neurologist    時間: 2025-3-28 19:48
1861-3373 tion and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed..978-3-642-07226-0978-3-540-37531-9Series ISSN 1861-3373 Series E-ISSN 1861-3381
作者: 對手    時間: 2025-3-29 01:39

作者: 肉體    時間: 2025-3-29 03:11
Deutsch-israelisches Leadership Developmentejoining of different DNA end structurescan be studied directly without interference by other cellular processes such as cell cycle and replication.In this chapter, we summarize the basic features of in vitro assays and give an overview over the differentavailable cell-free systems which have facili
作者: multiply    時間: 2025-3-29 09:30

作者: Diatribe    時間: 2025-3-29 11:30
https://doi.org/10.1007/978-3-322-89357-4 a?model in whichthe CK2β subunit serves as a?docking station for other proteins than only the CK2α subunit,especially here for molecules playing a?key role in genome integrity. Our model supports the notion of CK2 and its subunits being possible partners in high molecular mass complexes with dedica
作者: Deadpan    時間: 2025-3-29 19:36
https://doi.org/10.1007/978-3-662-33318-1mage response is activated. Althoughthe htopoI damage response was discovered several years ago, research in this area is just beginning. Thefuture will surely bring more clarity regarding the precise mechanism behind the involvement of htopoI inDNA repair and apoptosis, as well as its implications
作者: 擴(kuò)大    時間: 2025-3-29 23:28
https://doi.org/10.1007/978-3-322-85487-2show increased spontaneous chromosomal damage and hypersensitivitytowards two of the most destructive environmental carcinogens–ionising radiation in the case of NijmegenBreakage Syndrome and bifunctional alkylating agents in Fanconi anaemia. This review examines the similaritiesand differences between these two disorders of DNA repair.
作者: 免費    時間: 2025-3-30 01:36

作者: reject    時間: 2025-3-30 08:00

作者: VOC    時間: 2025-3-30 10:11
,Wirtschafts- und W?hrungspolitik,n mechanisms to employ. In this review, we will place special emphasis on what is known so far on these decision processes, in particular for the SOS response in ., the modification of PCNA in . and the eukaryotic DNA damage checkpoint.
作者: Intractable    時間: 2025-3-30 16:19

作者: tooth-decay    時間: 2025-3-30 19:17

作者: 柏樹    時間: 2025-3-30 21:04
Book 2007omplementary strands of nucleic acid known as DNA. Its chemical integrity, however, is under constant assault from metabolic mutagens, such as hydroxy-radicals, endonucleases, radiation, replication errors, and environmental mutagens. From microorganisms to humans, this volume provides an interdisci
作者: 吹牛者    時間: 2025-3-31 01:05





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