標(biāo)題: Titlebook: Genetics of Melanoma; Carlos A. Torres-Cabala,Jonathan L. Curry Book 2016 Springer Science+Business Media New York 2016 genetics.melanoma. [打印本頁] 作者: Destruct 時間: 2025-3-21 18:14
書目名稱Genetics of Melanoma影響因子(影響力)
書目名稱Genetics of Melanoma影響因子(影響力)學(xué)科排名
書目名稱Genetics of Melanoma網(wǎng)絡(luò)公開度
書目名稱Genetics of Melanoma網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Genetics of Melanoma被引頻次
書目名稱Genetics of Melanoma被引頻次學(xué)科排名
書目名稱Genetics of Melanoma年度引用
書目名稱Genetics of Melanoma年度引用學(xué)科排名
書目名稱Genetics of Melanoma讀者反饋
書目名稱Genetics of Melanoma讀者反饋學(xué)科排名
作者: 商談 時間: 2025-3-21 21:44
The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanomammune responses through intrinsic mechanisms in tumor cells or adaptive resistance triggered by the immune response via negative feedback. Understanding how these processes are balanced in context of pathways regulating T-cell activation, migration, and differentiation, and T-cell dysfunction in tum作者: output 時間: 2025-3-22 04:01 作者: Concrete 時間: 2025-3-22 05:00 作者: Ceramic 時間: 2025-3-22 09:54
Inherited Gene Mutations in Melanoma, uncontrolled proliferation, and invasion of melanocytes to abort progressive and incurable disease. Our growing knowledge of the somatic mutations in melanogenesis and the hereditary melanoma susceptibility genes is enabling clinicians to manipulate the neoplastic genotypes and develop effective t作者: 錢財(cái) 時間: 2025-3-22 13:41
The MAPK Pathway in Melanomas in the MAPK pathway in melanomas include mutations in ., and .. The increased understanding of the biology and genetics of melanoma has generated interest in targeting the MAPK pathway for the treatment of melanoma. Vemurafenib, which targets the BRAF-V600E mutant protein, was the first FDA-approv作者: 錢財(cái) 時間: 2025-3-22 20:06 作者: 外形 時間: 2025-3-22 23:08 作者: 友好關(guān)系 時間: 2025-3-23 02:51
Molecular Platforms for Melanoma Mutation Analysis. Testing for these mutations can be useful in providing diagnostic, therapeutic, and prognostic information. Molecular diagnostic techniques for mutational analysis are becoming standard of care in melanoma as the detection of these mutations will contribute to the development of molecular classifi作者: ineptitude 時間: 2025-3-23 06:08 作者: Somber 時間: 2025-3-23 09:42 作者: FRAUD 時間: 2025-3-23 16:35 作者: 散步 時間: 2025-3-23 19:13 作者: 處理 時間: 2025-3-24 00:09 作者: 拋物線 時間: 2025-3-24 04:03 作者: 形上升才刺激 時間: 2025-3-24 07:40 作者: calamity 時間: 2025-3-24 12:26 作者: BRAWL 時間: 2025-3-24 15:40 作者: Sleep-Paralysis 時間: 2025-3-24 21:48
Der Mensch inmitten der Geschichteies, and clinical prevention/management guidelines for high-risk patients. Genetic counseling is an integral service owing to the surmounting evidence for the hereditary nature and genetic pathogenesis of melanoma. Genetic consulting addresses and provides patient education on genetic principles, ge作者: lipoatrophy 時間: 2025-3-25 02:32
Es werde Licht: Geist und Bewusstsein,operated by numerous immune checkpoint molecules to prevent autoimmune attacks on normal tissues. The strategy of using monoclonal antibodies to block the inhibitory immune checkpoint receptors of cytotoxic T-lymphocyte antigen-4 (CTLA-4), programmed cell death-1 (PD-1), and programmed cell death li作者: Presbycusis 時間: 2025-3-25 04:23 作者: Nuance 時間: 2025-3-25 10:49 作者: foppish 時間: 2025-3-25 14:29
https://doi.org/10.1007/978-3-8350-5529-2mmune responses through intrinsic mechanisms in tumor cells or adaptive resistance triggered by the immune response via negative feedback. Understanding how these processes are balanced in context of pathways regulating T-cell activation, migration, and differentiation, and T-cell dysfunction in tum作者: Insul島 時間: 2025-3-25 17:58
Mein unbekannter Bekannter Jan G.48,000 deaths. According to the Centers for Disease Control and Prevention, the rates of melanoma have doubled in the United States in the past 30 years. Melanoma is now the fifth most common cancer among men and the sixth most common cancer in women in the United States. Among people under age 50, 作者: 任命 時間: 2025-3-25 23:39 作者: nonradioactive 時間: 2025-3-26 00:57 作者: BUMP 時間: 2025-3-26 07:59 作者: 盟軍 時間: 2025-3-26 09:01
https://doi.org/10.1007/978-94-009-6074-9hway and the PI3K-AKT pathway. While targeted inhibition of BRAF/MEK have resulted in improved survival in patients with BRAF V600-mutated melanoma, therapeutic resistance is often the end result. The PI3K-AKT pathway plays a significant role in BRAF-/MEK-inhibitor resistance in melanoma patients an作者: 凈禮 時間: 2025-3-26 15:24
https://doi.org/10.1007/978-3-322-98775-4e molecular engine that drives melanoma are recurring activating ., ., ., and ./. mutations in addition to a subset of tumors with functional loss of BAP1. The identification of these mutations in a subset of cutaneous melanomas has led to the development of novel mutation-specific-targeted therapie作者: Irremediable 時間: 2025-3-26 18:49
https://doi.org/10.1007/978-3-322-94168-8. Testing for these mutations can be useful in providing diagnostic, therapeutic, and prognostic information. Molecular diagnostic techniques for mutational analysis are becoming standard of care in melanoma as the detection of these mutations will contribute to the development of molecular classifi作者: BIPED 時間: 2025-3-27 00:20
Es werde Licht: Geist und Bewusstsein,mmunotherapeutic approaches in this disease. Areas of active investigation have included the use of recombinant cytokines, either alone or in combination with other biologic response modifiers, cancer vaccines, gene therapy, adoptive immunotherapy, or monoclonal antibodies. Although cytokine therapi作者: galley 時間: 2025-3-27 02:30
https://doi.org/10.1007/978-3-642-49177-1 The most commonly found mutations in melanoma are ., ., and ., and this chapter provides a detailed overview of each gene, their association with clinical features, as well as currently approved and investigational targeted approaches for each of these mutations. Safety profiles and underlying mech作者: 使成整體 時間: 2025-3-27 09:04
https://doi.org/10.1007/978-3-658-22530-8argeted therapy benefit from reduction in tumor burden and improved overall survival..While the treatment benefits of targeted therapy hold promise, the development of dermatologic toxicity is an unforeseeable consequence. Recognition of these cutaneous adverse side effects will be important as we s作者: EXTOL 時間: 2025-3-27 13:09 作者: Astigmatism 時間: 2025-3-27 15:51
Genetics of Melanoma978-1-4939-3554-3Series ISSN 2626-1456 Series E-ISSN 2626-1464 作者: certain 時間: 2025-3-27 19:40
Carlos A. Torres-Cabala,Jonathan L. CurryExplores recent discoveries in the field of melanoma genetics.Provides practical information for physicians and scientists.Features up-to-date chapters written by experts.Includes supplementary materi作者: Tartar 時間: 2025-3-28 01:32 作者: 形狀 時間: 2025-3-28 02:51
Steffen Schaal,Konrad Kunsch,Steffen Kunschre also critical to regulate melanoma initiation, melanoma cell intravasation, colonization of distant sites, and formation of macrometastasis. Targeting the tumor microenvironment may increase the antitumor activity of current therapies for melanoma.作者: 揭穿真相 時間: 2025-3-28 07:46 作者: Oversee 時間: 2025-3-28 12:27 作者: 遭遇 時間: 2025-3-28 15:02
Die Grundlagen der Untersuchungion tool to predict prognosis and guide patient management continues to be histologic examination. Thus, this chapter describes the most important histologic factors that allow to render a diagnosis of melanoma and related lesions, with special emphasis to the AJCC/CAP classification of melanoma.作者: 受辱 時間: 2025-3-28 20:06
https://doi.org/10.1007/978-94-009-6074-9d may represent a crucial target for combination therapy. This chapter will describe the components of the PI3K-AKT pathway, highlight their role in cellular physiology and melanoma pathogenesis, and examine their potential for molecular-targeted therapy.作者: acrimony 時間: 2025-3-28 23:48 作者: 他一致 時間: 2025-3-29 05:37
The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanomaors has become a critical area of research. This chapter describes the immunoregulatory mechanisms in the melanoma tumor microenvironment and how positive and negative signaling elements can be harnessed to facilitate enhanced anti-tumor immune responses through immunotherapy.作者: Terminal 時間: 2025-3-29 07:17 作者: Intrepid 時間: 2025-3-29 12:00 作者: 符合國情 時間: 2025-3-29 17:58
Targeted Therapy in Melanomaanisms of resistance are presented. Lastly, ./. mutations, found in up to 80 % of uveal melanoma patients, are detailed, and new insights into the role of the PTEN/PI3K/AKT/mTOR pathway are discussed.作者: Between 時間: 2025-3-29 19:59 作者: Interlocking 時間: 2025-3-30 00:21
Molecular Platforms for Melanoma Mutation Analysistional analysis are becoming standard of care in melanoma as the detection of these mutations will contribute to the development of molecular classification of melanocytic tumors and guides through choosing the most appropriate therapy in the era of personalized medicine.作者: 無能力之人 時間: 2025-3-30 04:42
Book 2016genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal expe作者: 感情 時間: 2025-3-30 10:40
https://doi.org/10.1007/978-94-017-0958-3athway alterations to melanoma development. We also discuss the association between mutations in particular genes and specific melanoma subtypes and the role of MAPK alterations in melanoma diagnosis. Therapeutic agents, in various stages of development, which target members of the MAPK pathway, are also discussed.作者: myelography 時間: 2025-3-30 15:53
