標(biāo)題: Titlebook: Genetics of Diabetes Mellitus; William L. Lowe Book 2001 Springer Science+Business Media New York 2001 Diabetes.Diabetes mellitus.genes.ge [打印本頁] 作者: 味覺沒有 時間: 2025-3-21 19:03
書目名稱Genetics of Diabetes Mellitus影響因子(影響力)
書目名稱Genetics of Diabetes Mellitus影響因子(影響力)學(xué)科排名
書目名稱Genetics of Diabetes Mellitus網(wǎng)絡(luò)公開度
書目名稱Genetics of Diabetes Mellitus網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Genetics of Diabetes Mellitus被引頻次
書目名稱Genetics of Diabetes Mellitus被引頻次學(xué)科排名
書目名稱Genetics of Diabetes Mellitus年度引用
書目名稱Genetics of Diabetes Mellitus年度引用學(xué)科排名
書目名稱Genetics of Diabetes Mellitus讀者反饋
書目名稱Genetics of Diabetes Mellitus讀者反饋學(xué)科排名
作者: Enthralling 時間: 2025-3-21 22:52 作者: 咒語 時間: 2025-3-22 03:53
Mouse Models of Type 2 Diabetes,genic pathogenesis. To dissect the complex genetics of insulin resistance and beta cell dysfunction, investigators have generated transgenic and knock-out mice bearing various mutations in genes required for insulin action and/or insulin secretion. This chapter reviews recent progress in the field and analyzes outstanding questions.作者: confide 時間: 2025-3-22 05:39
1566-0729 d geneticists who seek to learnmore about this rapidly changing and important field. The textcontains chapters from experts in the area who review aspects of thegenetics of both type 1 and 2 diabetes mellitus as well as varioussyndromic forms of diabetes. The chapters are approachable for thosewho a作者: 眼界 時間: 2025-3-22 10:58 作者: LIEN 時間: 2025-3-22 14:45
https://doi.org/10.1007/978-3-662-29157-3ing hyperglycemia occurs when impaired islet ?-cell function results in an underproduction of insulin relative to the prevailing insulin sensitivity (.). This chapter aims to provide the basis for the understanding of ?-cell function measurements . as much as this can be useful in unraveling the genetic basis of type 2 diabetes.作者: LIEN 時間: 2025-3-22 18:42 作者: 殘忍 時間: 2025-3-22 23:44 作者: flaggy 時間: 2025-3-23 02:33
Genetics of Complex Diseases, the insulin gene for type 1 diabetes (.–.) and apolipoprotein E for late-onset Alzheimer’s disease (.–.), few genes have been confirmed to have a functional role in the etiology of complex human disease. However, newer developments in molecular methodologies make the prospects of finding complex di作者: coagulate 時間: 2025-3-23 06:27 作者: 漂亮才會豪華 時間: 2025-3-23 13:08
Type 1 Diabetes, Autoimmunity, and the MHC,haracterized by a more gradual onset of mild to severe hyperglycemia, typically in an obese adult (maturity onset diabetes). The vast majority (>90%) of patients with juvenile diabetes are dependent on exogenous insulin for survival (insulin-dependent diabetes, IDDM); while the vast majority (>80%) 作者: Impugn 時間: 2025-3-23 15:39 作者: nerve-sparing 時間: 2025-3-23 22:03
Genetics of Mitochondria-Related Forms of Syndromic Diabetes Mellitus,tion. Neurological defects such as psychomotor retardation, hypotonia or ataxia, myo-or cardiomyopathies, optic atrophy or sensorineural hearing loss are among the most frequent clinical symptoms observed in OXPHOS disorders. Because of their high metabolic activity, pancreatic I3-cells are also hig作者: extinct 時間: 2025-3-24 00:38 作者: insolence 時間: 2025-3-24 04:39
Candidate Genes for Type 2 Diabetes,ype 2 diabetes is polygenic, i.e., it is inherited in a non-Mendelian fashion and onset of the disease requires the simultaneous presence of a subset of susceptibility genes whose gene products affect insulin production, secretion or sensitivity (.–.). This has complicated efforts to identify diabet作者: NUDGE 時間: 2025-3-24 08:07 作者: 使閉塞 時間: 2025-3-24 13:07 作者: 漫步 時間: 2025-3-24 15:57 作者: osteoclasts 時間: 2025-3-24 21:03 作者: FLUSH 時間: 2025-3-25 02:57 作者: rectum 時間: 2025-3-25 06:18
https://doi.org/10.1007/978-3-7091-9951-0natal nutritional experience and the occurrence of Type 2 diabetes as an adult. This has been well described in the Native American population known as the Pima Indians of Arizona; in comparing the offspring of Type 2 diabetic mothers, the presence of hyperglycemia in utero is associated with a much作者: 商業(yè)上 時間: 2025-3-25 08:21 作者: Inelasticity 時間: 2025-3-25 14:22
1566-0729 ants on the pathophysiology of type 2diabetes is covered, as are chapters that address specific genes thatare important for the development of type 2 diabetes. 978-1-4613-5633-2978-1-4615-1597-5Series ISSN 1566-0729 作者: Seminar 時間: 2025-3-25 19:08 作者: Obstacle 時間: 2025-3-25 21:49
Genetics of Complex Diseases,lex diseases are characterized as those traits that run in families and are commonly found in the population, but do not exhibit a simple mode of inheritance. They are often referred to as multifactorial because evidence suggests that complex diseases are caused by more than one gene, likely in comb作者: 助記 時間: 2025-3-26 02:43
Genetic Factors in Type 1 Diabetes,reatic ?-cells and complete insulin deficiency (.). The disease develops predominantly in children or adolescents, but it can develop at a much later age, and it is quite heterogeneous in its clinical expression. A large body of evidence indicates that inherited genetic factors influence both suscep作者: 饒舌的人 時間: 2025-3-26 05:25
Type 1 Diabetes, Autoimmunity, and the MHC,ce considered a geneticist’s nightmare (.), diabetes mellitus has recently emerged as a prototype for genetic studies of complex diseases. The ultimate goal of genetic studies is to define etiological subtypes by resolving genetic heterogeneity. The transition of diabetes from a geneticist’s nightma作者: Intercept 時間: 2025-3-26 11:34 作者: FLORA 時間: 2025-3-26 14:09 作者: 休閑 時間: 2025-3-26 18:04
Genetics of Mitochondria-Related Forms of Syndromic Diabetes Mellitus,upling the electron flux along the respiratory chain to the process of oxidative phosphorylation (OXPHOS). Depending on their energy demand, different cell types contain different amounts of mitochondria, ranging from only a few in the spermatozoon to several thousands in cells of skeletal muscle, h作者: MAOIS 時間: 2025-3-27 00:42
Regulation of Insulin Secretion in Vivo,es. Normal glucose regulation is dependent on a closed feedback loop relationship among the liver, peripheral tissues (primarily muscle) and pancreatic islet cells (.). In individuals with normal islet function, the pancreatic islet B-cell adapts to reductions in insulin sensitivity in the hepatic a作者: 笨重 時間: 2025-3-27 04:19 作者: 注意力集中 時間: 2025-3-27 07:51
Mouse Models of Type 2 Diabetes, recognized to precede beta cell dysfunction, a decreased capacity of the beta cell to compensate for increased insulin production can be demonstrated in healthy first degree relatives of diabetic patients, consistent with a genetic etiology of both defects. Both traits are inherited in a non-Mendel作者: 翻布尋找 時間: 2025-3-27 11:00
Candidate Genes for Type 2 Diabetes,0-cell dysfunction that is manifest as inadequate insulin secretion in the face of insulin resistance and hyperglycemia (see Chapters 7 and 8) (.,.). Previous studies have established a clear genetic predisposition for type 2 diabetes (.–.). The concordance rate among monozygotic twins is 50 to 90% 作者: 收養(yǎng) 時間: 2025-3-27 14:44 作者: Offensive 時間: 2025-3-27 19:46 作者: 流動性 時間: 2025-3-27 22:09 作者: 小故事 時間: 2025-3-28 04:11
Chronische Arthritis durch Trauma?,lex diseases are characterized as those traits that run in families and are commonly found in the population, but do not exhibit a simple mode of inheritance. They are often referred to as multifactorial because evidence suggests that complex diseases are caused by more than one gene, likely in comb作者: 非秘密 時間: 2025-3-28 09:38 作者: nugatory 時間: 2025-3-28 14:08
https://doi.org/10.1007/978-3-662-37022-3ce considered a geneticist’s nightmare (.), diabetes mellitus has recently emerged as a prototype for genetic studies of complex diseases. The ultimate goal of genetic studies is to define etiological subtypes by resolving genetic heterogeneity. The transition of diabetes from a geneticist’s nightma作者: 四目在模仿 時間: 2025-3-28 15:32 作者: Urea508 時間: 2025-3-28 19:47 作者: 強(qiáng)行引入 時間: 2025-3-29 01:53
https://doi.org/10.1007/978-3-7091-4803-7upling the electron flux along the respiratory chain to the process of oxidative phosphorylation (OXPHOS). Depending on their energy demand, different cell types contain different amounts of mitochondria, ranging from only a few in the spermatozoon to several thousands in cells of skeletal muscle, h作者: 繁殖 時間: 2025-3-29 04:11 作者: 形上升才刺激 時間: 2025-3-29 08:37
https://doi.org/10.1007/978-3-7091-9951-0 basis, most clearly indicated by the roughly 70% concordance in identical sibs, a concordance at least twice as high as in nonidentical sibs, and also considerably higher than the 30-40% concordance observed in identical twins sets, wherein one sib has autoimmune Type 1 diabetes (.). Despite this c作者: Engaged 時間: 2025-3-29 12:32 作者: IST 時間: 2025-3-29 19:04
Der Knigge für das Bankgesch?ft0-cell dysfunction that is manifest as inadequate insulin secretion in the face of insulin resistance and hyperglycemia (see Chapters 7 and 8) (.,.). Previous studies have established a clear genetic predisposition for type 2 diabetes (.–.). The concordance rate among monozygotic twins is 50 to 90% 作者: micturition 時間: 2025-3-29 23:07
Der Kolportagebuchhandel (1869-1905)ons worldwide. The concordance rates for diabetes in monozygotic twins are 50% or higher, whereas those for dizygotic twins are substantially lower, at 10 to 17% (.–.). It is estimated that siblings of diabetic individuals are 1.2 to 3 times more likely to have diabetes compared to the population, d
