標(biāo)題: Titlebook: Genes, Development and Cancer; The Life and Work of Howard D. Lipshitz (Senior Scientist and Head, Pro Book 2004 Kluwer Academic Publishers [打印本頁] 作者: broach 時(shí)間: 2025-3-21 18:03
書目名稱Genes, Development and Cancer影響因子(影響力)
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書目名稱Genes, Development and Cancer網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Genes, Development and Cancer被引頻次
書目名稱Genes, Development and Cancer被引頻次學(xué)科排名
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書目名稱Genes, Development and Cancer讀者反饋學(xué)科排名
作者: 大都市 時(shí)間: 2025-3-21 23:58 作者: 補(bǔ)充 時(shí)間: 2025-3-22 03:16
Book 2004 this is availability, man ny having been published in obscure journalsor as book chapters. A second is because his papers in those ?elds are very dif?cult to read. The dif?culty derives from the fact that Lewis has published infrequently, thus manypapers are condensed reviews of man nyyears’ work p作者: 墊子 時(shí)間: 2025-3-22 06:54
https://doi.org/10.1007/978-3-322-92440-7 was put to experimental test by Sturtevant (1928) for the dominant mutants, Delta (.) and Hairless (.), three units apart in the third chromosome; however, no difference could be demonstrated between ./++ and .+/+..作者: UNT 時(shí)間: 2025-3-22 10:33
Models of Love as Social Connections,, 1962), or lactose utilization in . (Jacob and Monod, 1961a,b). It may be anticipated that pseudoallelic series affecting morphological traits, such as the case to be described below, can also be profitably exploited to learn more about how genes control developmental pathways.作者: Grating 時(shí)間: 2025-3-22 15:04
The Relation of Repeats to Position Effect in , was put to experimental test by Sturtevant (1928) for the dominant mutants, Delta (.) and Hairless (.), three units apart in the third chromosome; however, no difference could be demonstrated between ./++ and .+/+..作者: Grating 時(shí)間: 2025-3-22 18:51 作者: 公豬 時(shí)間: 2025-3-22 22:37
Star-Recessive, A Spontaneous Mutation in ,ere mated ., all of the F. had abnormal eyes, but these varied in size from that of S/+ (see Table IV) to a narrow slit of red pigment on which only a few facets were scattered. A clue to the manner of inheritance of the type with narrow eyes was found by mating a narrow-eye male to a wild-type female, with the result shown in Table I: 作者: 誘拐 時(shí)間: 2025-3-23 02:26 作者: milligram 時(shí)間: 2025-3-23 07:01 作者: chastise 時(shí)間: 2025-3-23 11:32
A Gene Complex Controlling Segmentation in , a repressor of the complex. The wild-type and mutant segmentation patterns are consistent with an antero-posterior gradient in repressor concentration along the embryo and a proximo-distal gradient along the chromosome in the affinities for repressor of each gene’s .-regulatory element.作者: Calculus 時(shí)間: 2025-3-23 17:16
addition, historians of science will find it to be a valuablWhile Edward B. (‘Ed’) Lewis is famous for his contributions to genetics anddev- opmental biology y, few have read his research papers. One reason for this is availability, man ny having been published in obscure journalsor as book chapters作者: 一再煩擾 時(shí)間: 2025-3-23 21:57
In the Name of Cultural Studies,ere mated ., all of the F. had abnormal eyes, but these varied in size from that of S/+ (see Table IV) to a narrow slit of red pigment on which only a few facets were scattered. A clue to the manner of inheritance of the type with narrow eyes was found by mating a narrow-eye male to a wild-type female, with the result shown in Table I: 作者: 胎兒 時(shí)間: 2025-3-24 01:15
https://doi.org/10.1007/978-3-663-12005-6ene; while the extreme form, called Ultra-Bar or Double-Bar, was interpreted as a duplication for that gene. Later, Wright2 suggested that Bar itself had something additional present which when lost by unequal crossing-over would give back a normal chromosome (Bar-reverted).作者: 宿醉 時(shí)間: 2025-3-24 02:35
,What’s the Matter with Materialism(s)?,es in which there is a position effect or phenotypic difference between the “cis-type” (./++) and “trans-type” (.+/+.) of double mutant heterozygote. In most of these examples a close functional relationship between the adjoining loci is indicated.作者: 裹住 時(shí)間: 2025-3-24 09:52 作者: STANT 時(shí)間: 2025-3-24 11:21 作者: 意見一致 時(shí)間: 2025-3-24 18:10
Howard D. Lipshitz (Senior Scientist and Head, ProProvides source material for advanced undergraduate and graduate level courses in genetics, developmental biology, radiation and cancer..In addition, historians of science will find it to be a valuabl作者: 通知 時(shí)間: 2025-3-24 22:03 作者: 鬧劇 時(shí)間: 2025-3-24 23:19 作者: 閑逛 時(shí)間: 2025-3-25 06:48 作者: ALIAS 時(shí)間: 2025-3-25 08:18 作者: 迷住 時(shí)間: 2025-3-25 11:44
https://doi.org/10.1007/978-1-349-26830-6 laws. How fortunate that Mendel did not discover linkage, for he might then have failed to deduce the second law. How fortunate, too, that Mendel, by having chosen to work on peas, failed to discover “gene conversion,” not to mention “meiotic drive,” for he might then have failed to deduce even the first law.作者: overweight 時(shí)間: 2025-3-25 16:05 作者: Eulogy 時(shí)間: 2025-3-25 22:27
Lewis and the Nature of the Geneapping by meiotic recombination, discovery of rearranged chromosomes, proof that ionizing radiation causes mutations, discovery and mapping of salivary gland polytene chromosomes, and the cytogenetic mapping of chromosomal rearrangements on these chromosomes (reviewed in Sturtevant, 1965).作者: neutral-posture 時(shí)間: 2025-3-26 01:25
Pseudoallelism and Gene Evolutionts, may provide clues to the mode of origin of new kinds of genes.Our underlying thesis will be that in those instances of pseudoallelism in which there is evidence for close functional similarity among the component genes we may come close to seeing the direct results of a process which produces new genes.作者: 厭惡 時(shí)間: 2025-3-26 07:47
The Theory and Application of a New Method of Detecting Chromosomal Rearrangements in ,rom nuclear detonations. The method, itself, is an outgrowth of studies of the bithorax pseudoallelic genes near the middle of the right arm of the third chromosome (Lewis, 1951). It will be called the “bithorax” method. Results of applying it to the detection of X-ray induced rearrangements will be considered first.作者: 軍械庫 時(shí)間: 2025-3-26 09:06 作者: 蕨類 時(shí)間: 2025-3-26 16:41
Early Contacts Between Bali and IndiaThe bithorax complex (BX-C) is a set of master control genes that regulates other genes outside the complex to program much of the development of the thorax and abdomen of the fly. The emphasis in this paper will be on how the genes of the complex are themselves regulated, rather than on how they regulate other genes.作者: 談判 時(shí)間: 2025-3-26 17:56 作者: Crepitus 時(shí)間: 2025-3-26 23:22 作者: 吹牛大王 時(shí)間: 2025-3-27 04:36 作者: enfeeble 時(shí)間: 2025-3-27 08:36
LEGO Porn: Phallic Pleasure and Knowledgeapping by meiotic recombination, discovery of rearranged chromosomes, proof that ionizing radiation causes mutations, discovery and mapping of salivary gland polytene chromosomes, and the cytogenetic mapping of chromosomal rearrangements on these chromosomes (reviewed in Sturtevant, 1965).作者: 我不明白 時(shí)間: 2025-3-27 09:30
In the Name of Cultural Studies,larity in the arrangement of eye facets and facet hairs, the homozygote being lethal), a number of flies appeared with small narrow eyes. When these were mated ., all of the F. had abnormal eyes, but these varied in size from that of S/+ (see Table IV) to a narrow slit of red pigment on which only a作者: 導(dǎo)師 時(shí)間: 2025-3-27 13:45
https://doi.org/10.1007/978-3-663-12005-6ar. This behavior was shown by Sturtevant1 to result from unequal crossing-over. The Bar-reverted type was considered to be a deficiency for the Bar gene; while the extreme form, called Ultra-Bar or Double-Bar, was interpreted as a duplication for that gene. Later, Wright2 suggested that Bar itself 作者: Relinquish 時(shí)間: 2025-3-27 19:12 作者: Agility 時(shí)間: 2025-3-27 22:08 作者: Iniquitous 時(shí)間: 2025-3-28 05:53
Cultural Studies‘ Affective Voicests, may provide clues to the mode of origin of new kinds of genes.Our underlying thesis will be that in those instances of pseudoallelism in which there is evidence for close functional similarity among the component genes we may come close to seeing the direct results of a process which produces ne作者: ethnology 時(shí)間: 2025-3-28 08:45 作者: 滑稽 時(shí)間: 2025-3-28 11:21
,What’s the Matter with Materialism(s)?,nctional aspect will be the central theme of this paper. Attention will be focused chiefly on examples of “position pseudoallelism;” namely, those cases in which there is a position effect or phenotypic difference between the “cis-type” (./++) and “trans-type” (.+/+.) of double mutant heterozygote. 作者: gene-therapy 時(shí)間: 2025-3-28 18:33
https://doi.org/10.1007/978-1-349-26830-6 laws. How fortunate that Mendel did not discover linkage, for he might then have failed to deduce the second law. How fortunate, too, that Mendel, by having chosen to work on peas, failed to discover “gene conversion,” not to mention “meiotic drive,” for he might then have failed to deduce even the作者: Isthmus 時(shí)間: 2025-3-28 22:44 作者: 百靈鳥 時(shí)間: 2025-3-29 00:31 作者: Evacuate 時(shí)間: 2025-3-29 04:13 作者: 繞著哥哥問 時(shí)間: 2025-3-29 07:21 作者: expound 時(shí)間: 2025-3-29 15:00
https://doi.org/10.1057/9781137478290f the organism. From developmental and cytogenetic studies of this complex it now appears that orderly derepression of BX-C genes controls the orderly differentiation of body segments commencing with the thorax and proceeding posteriorly. The available evidence also suggests that the level of develo作者: gospel 時(shí)間: 2025-3-29 16:26
https://doi.org/10.1007/978-3-663-07754-1a position effect.. In such cases, which have been termed “position pseudoalleles,”. mutant genes at the different loci (say, . and .) give a mutant phenotype in the .+/+. heterozygote, but a wild-type, or more nearly wild-type, phenotype in the ./++ heterozygote.作者: 圓桶 時(shí)間: 2025-3-29 21:47 作者: 使乳化 時(shí)間: 2025-3-30 01:15 作者: Entirety 時(shí)間: 2025-3-30 05:23
d to place the papers in historical perspective, with respect to Lewis’ own ideas as well as to those of the larger scienti?c community. The commentaries attempt to highlight the key methods and results—as well978-1-4613-4746-0978-1-4419-8981-9作者: 通便 時(shí)間: 2025-3-30 10:13 作者: 枕墊 時(shí)間: 2025-3-30 13:17
Lewis and the Genetic Control of Developmentsiologist is concerned with processes going on in the cell, but has no means of finding out at present how far the chromosomes may or may not have affected the process. He is, however, as a rule sufficiently broad-minded to concede at least that any change in the complex of factors present in a cell作者: BILL 時(shí)間: 2025-3-30 18:20 作者: 小淡水魚 時(shí)間: 2025-3-30 22:52 作者: LURE 時(shí)間: 2025-3-31 02:48
E. B. Lewis and His Science second half of the nineteenth century. These converged a century later to provide deep insights into the mechanistic basis of animal development, how genes control developmental processes, and the evolutionary origins of the metazoan body plan. This convergence was brought about, in no small part, 作者: 脫離 時(shí)間: 2025-3-31 07:04
Lewis and the Nature of the Geneapping by meiotic recombination, discovery of rearranged chromosomes, proof that ionizing radiation causes mutations, discovery and mapping of salivary gland polytene chromosomes, and the cytogenetic mapping of chromosomal rearrangements on these chromosomes (reviewed in Sturtevant, 1965).作者: 根除 時(shí)間: 2025-3-31 11:33
Star-Recessive, A Spontaneous Mutation in ,larity in the arrangement of eye facets and facet hairs, the homozygote being lethal), a number of flies appeared with small narrow eyes. When these were mated ., all of the F. had abnormal eyes, but these varied in size from that of S/+ (see Table IV) to a narrow slit of red pigment on which only a作者: 排名真古怪 時(shí)間: 2025-3-31 17:14 作者: NEG 時(shí)間: 2025-3-31 21:18
The Relation of Repeats to Position Effect in ,menon of position effect has been given by Sturtevant (1925), Dubinin and Sidorow (1935), and Panshin (1935). Position effects have been detected only in cases in which the relative position of a gene with respect to its neighbors has been altered by a chromosomal rearrangement. It is conceivable th作者: DEBT 時(shí)間: 2025-3-31 22:25
The Pseudoallelism of White and Apricot in ,es, namely, that it is made up of “pseudoalleles,” or closely linked genes with similar effects, has usually been considered ruled out by two kinds of evidence. In the first place early attempts to resolve the series by crossing over failed in spite of numerous tests involving most of the mutants av作者: noxious 時(shí)間: 2025-4-1 05:04
Pseudoallelism and Gene Evolutionts, may provide clues to the mode of origin of new kinds of genes.Our underlying thesis will be that in those instances of pseudoallelism in which there is evidence for close functional similarity among the component genes we may come close to seeing the direct results of a process which produces ne作者: 一起 時(shí)間: 2025-4-1 07:42
The Theory and Application of a New Method of Detecting Chromosomal Rearrangements in ,rom nuclear detonations. The method, itself, is an outgrowth of studies of the bithorax pseudoallelic genes near the middle of the right arm of the third chromosome (Lewis, 1951). It will be called the “bithorax” method. Results of applying it to the detection of X-ray induced rearrangements will be作者: LAPSE 時(shí)間: 2025-4-1 12:47
Some Aspects of Position Pseudoallelismnctional aspect will be the central theme of this paper. Attention will be focused chiefly on examples of “position pseudoallelism;” namely, those cases in which there is a position effect or phenotypic difference between the “cis-type” (./++) and “trans-type” (.+/+.) of double mutant heterozygote. 作者: 脫落 時(shí)間: 2025-4-1 17:16 作者: arsenal 時(shí)間: 2025-4-1 19:26
Lewis and the Genetic Control of Developmentespecially by chemistry may lead to the discovery of the physiological action of the genes” (Morgan, 1923). He went on to argue in favor of the fundamental role that genes must play in controlling development: “The embryologist observes the developmental changes taking place in the cytoplasm in the
