標(biāo)題: Titlebook: Genes and Environment in Cancer; Manfred Schwab,Hartmut M. Rabes,Hans Peter Hofschn Conference proceedings 1998 Springer-Verlag Berlin · H [打印本頁] 作者: Autopsy 時間: 2025-3-21 18:23
書目名稱Genes and Environment in Cancer影響因子(影響力)
書目名稱Genes and Environment in Cancer影響因子(影響力)學(xué)科排名
書目名稱Genes and Environment in Cancer網(wǎng)絡(luò)公開度
書目名稱Genes and Environment in Cancer網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Genes and Environment in Cancer被引頻次
書目名稱Genes and Environment in Cancer被引頻次學(xué)科排名
書目名稱Genes and Environment in Cancer年度引用
書目名稱Genes and Environment in Cancer年度引用學(xué)科排名
書目名稱Genes and Environment in Cancer讀者反饋
書目名稱Genes and Environment in Cancer讀者反饋學(xué)科排名
作者: 自作多情 時間: 2025-3-21 21:54
Molecular Epidemiology of Human Cancertro and in vivo laboratory models, biochemistry and epidemiology to infer individual cancer risk. Molecular dosimetry of carcinogen exposure is an important facet of molecular epidemiology and cancer risk assessment. Carcinogen macromolecular adduct levels, cytogenetic alterations and somatic cell m作者: 形容詞詞尾 時間: 2025-3-22 02:37
Molecular Epidemiology of Environmental Carcinogenesisiefly reviews molecular evidence that two types of susceptibility factors — common predisposing genetic traits and young age at exposure — convey heightened risk from certain exposures. Examples are drawn from molecular epidemiologic studies of common environmental carcinogens such as polycyclic aro作者: ARCHE 時間: 2025-3-22 04:37 作者: Galactogogue 時間: 2025-3-22 08:57 作者: 環(huán)形 時間: 2025-3-22 16:17 作者: 環(huán)形 時間: 2025-3-22 18:44 作者: CAMP 時間: 2025-3-22 21:54
Molecular Basis of DNA Repair Mechanisms and Syndromes in the nucleotide sequence varying from point mutations to gross chromosomal aberrations which can alter the expression or functioning of genes implicated in regulation of cell proliferation and differentiation, thereby forwarding the cell in the multistep process of carcinogenesis. To prevent thes作者: 水槽 時間: 2025-3-23 01:53 作者: 玩忽職守 時間: 2025-3-23 08:09 作者: optic-nerve 時間: 2025-3-23 10:18 作者: patella 時間: 2025-3-23 16:39
The Role of Deletions at the , Locus in Carcinogenesisabase genomic region at chromosome band 3p14.2. The gene encompasses the most active of the common human chromosomal fragile regions, .. Over the years, it has been suggested that fragile sites might be especially susceptible to carcinogen damage and that chromosomal regions of nonrandom alterations作者: Misgiving 時間: 2025-3-23 19:15 作者: Ankylo- 時間: 2025-3-24 02:14
Mechanisms of Development of Multiple Endocrine Neoplasia Type 2 and Hirschsprung’s Disease by , Mut Its germline mutations are responsible for the development of multiple endocrine neoplasia (MEN) types 2A and 2B and Hirschsprung’s disease (HSCR). MEN2A and MEN2B mutations result in the constitutive activation of Ret by different molecular mechanisms. MEN2A mutations involve cysteine residues pre作者: 搖曳 時間: 2025-3-24 03:37
https://doi.org/10.1007/978-3-642-46870-4DNA; Genetik; Termination; breast cancer; cancer; cancer therapy; carcinogenesis; carcinoma; chromosome; colo作者: 單獨 時間: 2025-3-24 09:59 作者: Ornithologist 時間: 2025-3-24 14:20 作者: Fantasy 時間: 2025-3-24 17:59 作者: 刺穿 時間: 2025-3-24 20:10 作者: amplitude 時間: 2025-3-25 01:27 作者: Cupping 時間: 2025-3-25 05:49 作者: Communal 時間: 2025-3-25 11:33 作者: Multiple 時間: 2025-3-25 14:13
Byron J. Good,Mary-Jo Delvecchio Goods process. Analysis of the frequency, type and site of mutations in important cancer-related genes may provide clues to the identification of etiological factors and sources of exposure. In this chapter we have selected a few examples of environmental human carcinogens and have attempted to use the 作者: Grandstand 時間: 2025-3-25 19:41 作者: 偏見 時間: 2025-3-25 20:51
Cultural Constructions of the Femme Fatale in the nucleotide sequence varying from point mutations to gross chromosomal aberrations which can alter the expression or functioning of genes implicated in regulation of cell proliferation and differentiation, thereby forwarding the cell in the multistep process of carcinogenesis. To prevent thes作者: locus-ceruleus 時間: 2025-3-26 04:00 作者: 不自然 時間: 2025-3-26 06:23 作者: Meager 時間: 2025-3-26 10:10 作者: perpetual 時間: 2025-3-26 13:06
Hindu Nationalism and Its Ramificationsabase genomic region at chromosome band 3p14.2. The gene encompasses the most active of the common human chromosomal fragile regions, .. Over the years, it has been suggested that fragile sites might be especially susceptible to carcinogen damage and that chromosomal regions of nonrandom alterations作者: Ethics 時間: 2025-3-26 20:05 作者: 不容置疑 時間: 2025-3-26 23:01 作者: GUILT 時間: 2025-3-27 01:17
Manfred Schwab,Hartmut M. Rabes,Hans Peter Hofschn作者: 忘川河 時間: 2025-3-27 06:53
https://doi.org/10.1007/978-3-030-63197-0the proportions of fatal cancers attributable to alcohol and ionizing radiation, and reasonable guesses can be made at the maximum effect of some of the other categories..Many of the factors act synergistically with one another, so that the risk of developing specific cancers can be modified in diff作者: RENIN 時間: 2025-3-27 11:33
https://doi.org/10.1007/978-1-349-09402-8ssor gene provide important clues for cancer risk assessment in molecular epidemiology. For example, characteristic . mutation spectra have been associated with: dietary aflatoxin B. exposure and hepatocellular carcinoma; sunlight exposure and skin carcinoma; and cigarette smoking and lung cancer. T作者: 摘要記錄 時間: 2025-3-27 15:20
Caroline Cummings,William O’Donohuedeletion of GSTM1 (GSTM1-0) and lung cancer (odds ratio: 1.41; 95% CI: 1.23-1.61). Combination of GSTM1-0 with two allelic variants of cytochrome P4501A1 (CYP1A1), CYP1A1 m2/m2 and CYP1A1 Val/Val further increases the risk for lung cancer. Indirect mechanisms by which deletion of GSTM1 increases ris作者: definition 時間: 2025-3-27 19:31
https://doi.org/10.1007/978-0-387-72171-2predisposing genes can then be used as intermediate risk markers rather than taking cancer as an endpoint. In case-control studies, simultaneous measurements were carried out in each subject to determine exposure/early effect markers, e.g. polycyclic aromatic hydrocarbons (PAH)-DNA adducts, and susc作者: animated 時間: 2025-3-28 00:00
Madness Itself: the Real Story,tGua), for example, differ only by one CH. group. These lesions are formed in DNA upon exposure to N-methyl-N-nitrosourea (MeNU) or N-ethyl-N-nitrosourea (EtNU), both of which induce mammary adenocarcinomas in female rats at high yield. Unrepaired O.-alkylguanines cause transition mutations via misp作者: 確定的事 時間: 2025-3-28 03:21
Cultural Constructions of the Femme Fataleth the rapid and efficient removal of lesions that block transcription and thus need to be eliminated urgently (transcription-coupled repair, TCR). The other accomplishes the slower and less efficient global genome repair (GGR) of bulk DNA, including the nontranscribed strand of active genes.作者: FIN 時間: 2025-3-28 09:29 作者: facilitate 時間: 2025-3-28 14:01
Borders, Boundaries and Difference, investigated at the molecular level. It extends over a broad region of possibly 500 kb, and no trinucleotide or other simple repeat motifs have been identified in the region. FRA3B has recently been shown to lie within the . gene locus. This region and the . gene are unstable in a number of tumors 作者: 傲慢物 時間: 2025-3-28 16:41
Hindu Nationalism and Its Ramificationses such as lung that are targets of carcinogens. This supports the proposed cancer-fragile site connection and suggests that the . gene, expression of which is frequently altered in cells showing . locus damage, is a tumor suppressor gene whose inactivation may drive clonal expansion of preneoplasti作者: 強(qiáng)化 時間: 2025-3-28 20:00
Cultural Diversity And Learning Efficiencyimpair the Ret cell surface expression. More interestingly, . mutations in cysteines 618 and 620 were reported in several families who developed both MEN2A and HSCR. It was suggested that these mutations might have two biological effects on Ret function, leading to the development of different clini作者: 芳香一點 時間: 2025-3-29 02:21
Epidemiological Evidence of the Effects of Behaviour and the Environment on the Risk of Human Cancerthe proportions of fatal cancers attributable to alcohol and ionizing radiation, and reasonable guesses can be made at the maximum effect of some of the other categories..Many of the factors act synergistically with one another, so that the risk of developing specific cancers can be modified in diff作者: palliate 時間: 2025-3-29 03:45 作者: iodides 時間: 2025-3-29 07:39
Polymorphisms of N-Acetyltransferases, Glutathione S-Transferases, Microsomal Epoxide Hydrolase and deletion of GSTM1 (GSTM1-0) and lung cancer (odds ratio: 1.41; 95% CI: 1.23-1.61). Combination of GSTM1-0 with two allelic variants of cytochrome P4501A1 (CYP1A1), CYP1A1 m2/m2 and CYP1A1 Val/Val further increases the risk for lung cancer. Indirect mechanisms by which deletion of GSTM1 increases ris作者: Temporal-Lobe 時間: 2025-3-29 14:28
Impact of Adduct Determination on the Assessment of Cancer Susceptibilitypredisposing genes can then be used as intermediate risk markers rather than taking cancer as an endpoint. In case-control studies, simultaneous measurements were carried out in each subject to determine exposure/early effect markers, e.g. polycyclic aromatic hydrocarbons (PAH)-DNA adducts, and susc作者: 生命層 時間: 2025-3-29 18:18
Relevance of DNA Repair to Carcinogenesis and Cancer TherapytGua), for example, differ only by one CH. group. These lesions are formed in DNA upon exposure to N-methyl-N-nitrosourea (MeNU) or N-ethyl-N-nitrosourea (EtNU), both of which induce mammary adenocarcinomas in female rats at high yield. Unrepaired O.-alkylguanines cause transition mutations via misp作者: 死亡率 時間: 2025-3-29 20:58
Molecular Basis of DNA Repair Mechanisms and Syndromesth the rapid and efficient removal of lesions that block transcription and thus need to be eliminated urgently (transcription-coupled repair, TCR). The other accomplishes the slower and less efficient global genome repair (GGR) of bulk DNA, including the nontranscribed strand of active genes.作者: obstruct 時間: 2025-3-30 02:26
The Ataxia Telangiectasia Gene in Familial and Sporadic CancerOur finding of a surfeit of mutations within . may reflect the involvement of the gene at more than one step in tumorigenesis. In particular, we suggest that the clustering of missense mutations may pertain to the late-onset character of both sporadic and A-T-related T-PLL, since the closest homolog作者: 吊胃口 時間: 2025-3-30 04:52 作者: 笨拙的你 時間: 2025-3-30 10:42
The Role of Deletions at the , Locus in Carcinogenesises such as lung that are targets of carcinogens. This supports the proposed cancer-fragile site connection and suggests that the . gene, expression of which is frequently altered in cells showing . locus damage, is a tumor suppressor gene whose inactivation may drive clonal expansion of preneoplasti作者: visceral-fat 時間: 2025-3-30 15:04 作者: fetter 時間: 2025-3-30 19:47
Michele Willsher,Janine Oldfieldmatic hydrocarbons (PAH) and aromatic amines. Understanding of both genetic and acquired susceptibility in the population will be instrumental in developing health and regulatory policies that adequately protect of the more susceptible groups from risks of environmental carcinogens.作者: Reservation 時間: 2025-3-30 22:19
https://doi.org/10.1057/9780230505209such as gender, age at testing, and time since testing, will be evaluated using Poisson regression models. Two other potential effect modifiers, occupational exposures and smoking, will be assessed in a case-referent study within the study base.作者: Abjure 時間: 2025-3-31 00:50
Molecular Epidemiology of Environmental Carcinogenesismatic hydrocarbons (PAH) and aromatic amines. Understanding of both genetic and acquired susceptibility in the population will be instrumental in developing health and regulatory policies that adequately protect of the more susceptible groups from risks of environmental carcinogens.作者: 老人病學(xué) 時間: 2025-3-31 06:00
Cancer Predictive Value of Cytogenetic Markers Used in Occupational Health Surveillance Programssuch as gender, age at testing, and time since testing, will be evaluated using Poisson regression models. Two other potential effect modifiers, occupational exposures and smoking, will be assessed in a case-referent study within the study base.作者: facetious 時間: 2025-3-31 12:48
0080-0015 . The major aim of this book is to present an integrated view of the various environmental, epidemiological and genetic determinants that contribute to a disease syndrome collectively known as "cancer".978-3-642-46872-8978-3-642-46870-4Series ISSN 0080-0015 Series E-ISSN 2197-6767 作者: 閑逛 時間: 2025-3-31 15:43
