標(biāo)題: Titlebook: Gene- and Cell-Based Treatment Strategies for the Eye; Elizabeth P. Rakoczy Book 2015 Springer-Verlag Berlin Heidelberg 2015 Complex eye d [打印本頁] 作者: 喜悅 時間: 2025-3-21 18:31
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書目名稱Gene- and Cell-Based Treatment Strategies for the Eye讀者反饋
書目名稱Gene- and Cell-Based Treatment Strategies for the Eye讀者反饋學(xué)科排名
作者: 籠子 時間: 2025-3-21 21:25 作者: 托運(yùn) 時間: 2025-3-22 03:49 作者: 多嘴多舌 時間: 2025-3-22 06:29
Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium for the Treatment oon the first two patients, one with dry AMD and one with Stargardt’s. Functional improvements were observed, but our conclusions were limited by the short follow-up time, lack of control group, and poor initial visual acuity. Importantly, no adverse events related to the treatment, such as hyperprol作者: angiography 時間: 2025-3-22 09:58 作者: LVAD360 時間: 2025-3-22 15:30 作者: LVAD360 時間: 2025-3-22 19:00
Book 2015ments for eye disease without compromising on accurate reporting of scientific facts. It will persuade the average practitioner or researcher – whether ophthalmologist, health worker, or scientist – that change is indeed coming and is not just a hollow promise of the tabloid media.作者: 疲勞 時間: 2025-3-23 00:11
https://doi.org/10.1007/978-3-030-46324-3ies that could lead to the first approved gene therapy in the USA. Approval of the first gene therapy reagent as a prescribed medicine will not only give promise to many individuals born blind due to inherited mutations but will also pave the way for the development of additional retinal gene therap作者: Adrenaline 時間: 2025-3-23 02:51
Núria Amigó Grau,Pablo Ortiz Betestic diagnosis. After several decades of research, we now have a clearer understanding of the exact pathogenesis, but despite this, no established treatments currently exist to stop or even slow the progression of retinal degeneration in choroideremia. Fortunately, some specific molecular and clinica作者: EXUDE 時間: 2025-3-23 06:18
Ethics: Informed Consent, Patient Privacyy inherited retinal disorders will be discussed. Therapies targeted toward correcting the primary genetic mutations driving the disease process, or toward modulating secondary effects associated with the disease course, are reviewed. The possibility of combining such approaches to optimize efficacy 作者: 輕信 時間: 2025-3-23 11:11
https://doi.org/10.1007/1-4020-2586-6on the first two patients, one with dry AMD and one with Stargardt’s. Functional improvements were observed, but our conclusions were limited by the short follow-up time, lack of control group, and poor initial visual acuity. Importantly, no adverse events related to the treatment, such as hyperprol作者: Keratin 時間: 2025-3-23 17:48
Monique M. Elseviers,Marc E. De Broeproach, utilizing surface-functionalized nanoparticles. Using this strategy, we are able to suppress choroidal neovascularization and fibrosis and restore visual acuity in several animal models including nonhuman primates. Our results show a promising alternative in our arsenal for anti-VEGF therapi作者: iodides 時間: 2025-3-23 21:20 作者: BACLE 時間: 2025-3-23 22:50
Laura Weiss Roberts MD, MA,Mark Siegler MDhe development of recombinant technologies that led to the generation of recombinant viruses was it possible to treat genetically inherited diseases. Cell therapies are also a new way of treating disease and here we provide an overview of the development of the field.作者: Restenosis 時間: 2025-3-24 04:39 作者: 專橫 時間: 2025-3-24 08:36
Book 2015al within the next 10–20 years. The treatments discussed relate to a wide variety of conditions, including macular degeneration, Leber’s congenital amaurosis, retinitis pigmentosa, choroideremia, and retinoschisis. The authors explain clearly how different gene and cell therapies work and provide fi作者: Receive 時間: 2025-3-24 13:21
Cellular mechanisms of nephrotoxicitylivery system. A detailed description of the construct, production, validation, and biological and pharmacological assessment follows. In addition, preclinical in vitro and in vivo data on mice, rats, and monkeys are presented. Finally, an early-stage clinical trial in human subjects is described.作者: medieval 時間: 2025-3-24 15:50 作者: 聯(lián)邦 時間: 2025-3-24 20:05
1612-3212 dge science into potential treatmentsIn this book, leading experts provide detailed descriptions of the exciting treatments that are expected to become part of the ophthalmologist’s arsenal within the next 10–20 years. The treatments discussed relate to a wide variety of conditions, including macula作者: shrill 時間: 2025-3-25 02:57
Elizabeth P. RakoczyExplains how emerging gene and stem cell therapies work.Covers treatments for a range of eye diseases.Describes the development of cutting-edge science into potential treatments作者: bronchiole 時間: 2025-3-25 07:21 作者: aviator 時間: 2025-3-25 10:49 作者: analogous 時間: 2025-3-25 15:13 作者: 潛移默化 時間: 2025-3-25 18:23
Laura Weiss Roberts MD, MA,Mark Siegler MD scientific discoveries that contributed, we have endeavored to crystallize the steps that were the most important and presented them in the context of scientific history. The birth of genetics led to the discovery of DNA, understanding of inheritance, variations, and mutations. However, not until t作者: 緩和 時間: 2025-3-25 21:42
https://doi.org/10.1007/978-3-030-46324-3’s congenital amaurosis (LCA) due to . mutations. In the past 7 years, eight different clinical trials have been carried out evaluating safety and efficacy of recombinant virus-mediated delivery of the normal copy of .. The studies have differed in a number of variables, including dose and volume of作者: Inoperable 時間: 2025-3-26 01:35
Núria Amigó Grau,Pablo Ortiz Betesh century. In sufferers, the appearance of the fundus is of a characteristic pale colour caused by the loss of the outer retina, retinal pigmented epithelium and choroidal vessels, leading to exposure of the underlying sclera. Visual symptoms begin with reduction of night vision and gradually progre作者: 原來 時間: 2025-3-26 08:03 作者: 巡回 時間: 2025-3-26 09:30 作者: Insensate 時間: 2025-3-26 14:58 作者: characteristic 時間: 2025-3-26 20:38
Monique M. Elseviers,Marc E. De Broertant role in disease burden and progression. Current therapies focus on inhibition of neovascularization through suppression of the extracellular VEGF pathway. However, these strategies have several disadvantages including the need for monthly injections and the need for direct injections of drug t作者: 流逝 時間: 2025-3-27 00:30 作者: Anguish 時間: 2025-3-27 01:48 作者: Esophagus 時間: 2025-3-27 07:52
Gene Therapy and Stem Cell Therapy: Overview, scientific discoveries that contributed, we have endeavored to crystallize the steps that were the most important and presented them in the context of scientific history. The birth of genetics led to the discovery of DNA, understanding of inheritance, variations, and mutations. However, not until t作者: neutralize 時間: 2025-3-27 10:08
,Gene Therapy for Leber’s Congenital Amaurosis Due to , Mutations,’s congenital amaurosis (LCA) due to . mutations. In the past 7 years, eight different clinical trials have been carried out evaluating safety and efficacy of recombinant virus-mediated delivery of the normal copy of .. The studies have differed in a number of variables, including dose and volume of作者: groggy 時間: 2025-3-27 13:40
Gene Therapy for Choroideremia,h century. In sufferers, the appearance of the fundus is of a characteristic pale colour caused by the loss of the outer retina, retinal pigmented epithelium and choroidal vessels, leading to exposure of the underlying sclera. Visual symptoms begin with reduction of night vision and gradually progre作者: 一大塊 時間: 2025-3-27 18:51 作者: 受傷 時間: 2025-3-27 23:50 作者: enlist 時間: 2025-3-28 06:10 作者: anaphylaxis 時間: 2025-3-28 09:31 作者: 原始 時間: 2025-3-28 12:22 作者: 坦白 時間: 2025-3-28 16:45
Literature Review,nd . in the years 1937, 1947, 1957, 1967, 1977 and 1986. Among other things, he found that “the most popular subject of family research over the 50-year period” was “family and premarital relationships”, and “The largest subcategory within this general grouping is marital happiness, unhappiness, and
