標題: Titlebook: Gene Therapy for Neurological Disorders and Brain Tumors; E. Antonio Chiocca,Xandra O. Breakefield Book 1998 Springer Science+Business Med [打印本頁] 作者: 嚴峻 時間: 2025-3-21 18:32
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors影響因子(影響力)
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors影響因子(影響力)學科排名
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors網(wǎng)絡(luò)公開度
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors網(wǎng)絡(luò)公開度學科排名
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors被引頻次
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors被引頻次學科排名
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors年度引用
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors年度引用學科排名
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors讀者反饋
書目名稱Gene Therapy for Neurological Disorders and Brain Tumors讀者反饋學科排名
作者: 樣式 時間: 2025-3-21 23:08
https://doi.org/10.1007/978-3-319-72850-6rly (IE), early, and late. The latent infection occurs in sensory ganglia and is characterized by a complete absence of lytic gene expression but for the synthesis of a set of transcripts (of unclear function) referred to as the latency-associated transcripts (LATs). The potential applications for a作者: 鑲嵌細工 時間: 2025-3-22 02:09 作者: 白楊魚 時間: 2025-3-22 06:06 作者: Harridan 時間: 2025-3-22 11:26
https://doi.org/10.1007/978-3-319-63290-2rapy. It includes an overview of the general properties of transcriptional regulation, an analysis of the mechanisms by which cell-specific gene expression is achieved by interactions between promoters, transcription factors, chromatin, and methylation, and summarizes transgenic studies of brain-spe作者: induct 時間: 2025-3-22 14:39 作者: induct 時間: 2025-3-22 20:40 作者: 懸掛 時間: 2025-3-22 23:08
Simone Sch?nfeld,Nadja Tschirnerto take advantage of the underlying genetic abnormalities of tumor cells, those that contribute to the unregulated growth of cancer cells, prevent apoptosis, activate angiogenic factors, induce proliferation, and promote invasiveness. One of the most promising new therapeutic approaches involves the作者: intertwine 時間: 2025-3-23 03:05
Soziale Gruppierungen manipulieren,ments in the context of the appropriateness of the experimental model may produce misleading conclusions that could delay the rational development of efficacious immunotherapeutic strategies. In the second part of this chapter, the recent literature dealing with the use of cytokine gene transfer to 作者: 壓倒性勝利 時間: 2025-3-23 08:55
Newcomer – die unbekannten Game Changer-oncology since the mid-1970s .. Druckrey ., Benda, Schmidek, Swenberg, and Koestner . and their associates reported that central nervous system tumors could be induced selectively and reproducibly in adult rats that had been given repeated, weekly, intravenous (iv) injections of N-methylnitrosourea作者: Sputum 時間: 2025-3-23 12:59
Gene Therapy for Neurological Disorders and Brain Tumors作者: OVERT 時間: 2025-3-23 13:58
Gene Therapy for Neurological Disorders and Brain Tumors978-1-59259-478-8作者: 他姓手中拿著 時間: 2025-3-23 21:44
Retrovirus Vectors and Regulatable Promotersin host-cells in the process of replicating and synthesizing their own genomic DNA (an exception is in the human immunodeficiency virus [HIV] family of retroviruses), which allows the targeting of the virus to rapidly dividing cells and not postmitotic cells .. The viral genes in the vector genome w作者: CHAFE 時間: 2025-3-23 22:39
HSV Recombinant Vectorsrly (IE), early, and late. The latent infection occurs in sensory ganglia and is characterized by a complete absence of lytic gene expression but for the synthesis of a set of transcripts (of unclear function) referred to as the latency-associated transcripts (LATs). The potential applications for a作者: 2否定 時間: 2025-3-24 05:13
AAV Vectors, integration occurs in a site-specific fashion: The majority of AAV sequences are found in a restricted area (AAVS1) on chromosome 19g13.3-qter .. This integration has not been associated with any ill effects on the host cell. The lack of pathogenicity and the ability to integrate site-specifically作者: 預定 時間: 2025-3-24 07:35 作者: 冰雹 時間: 2025-3-24 13:06
Promoters for Expression of Gene Products within Neurons and Gliarapy. It includes an overview of the general properties of transcriptional regulation, an analysis of the mechanisms by which cell-specific gene expression is achieved by interactions between promoters, transcription factors, chromatin, and methylation, and summarizes transgenic studies of brain-spe作者: 無思維能力 時間: 2025-3-24 14:50
Immune Response to Viral Vectors two clinical trials are currently underway using adenovirus vectors to treat gliomas .. Vector applications can be categorized on the basis of the desired duration of transgene expression and the effect of the immune response on the target cell. For example, correction of such disorders as Parkinso作者: PHAG 時間: 2025-3-24 21:08 作者: condescend 時間: 2025-3-25 02:59
Tumor Suppressor Gene Therapy for Brain Tumorsto take advantage of the underlying genetic abnormalities of tumor cells, those that contribute to the unregulated growth of cancer cells, prevent apoptosis, activate angiogenic factors, induce proliferation, and promote invasiveness. One of the most promising new therapeutic approaches involves the作者: Psa617 時間: 2025-3-25 06:07 作者: Commemorate 時間: 2025-3-25 11:11
Rat Brain Tumor Models and the Statistical Evaluation of Survival Data in Experimental Neuro-Oncolog-oncology since the mid-1970s .. Druckrey ., Benda, Schmidek, Swenberg, and Koestner . and their associates reported that central nervous system tumors could be induced selectively and reproducibly in adult rats that had been given repeated, weekly, intravenous (iv) injections of N-methylnitrosourea作者: Contort 時間: 2025-3-25 11:54
Monetizing Your Blog for Fun and Profit We will review the properties of adenovirus vectors that are responsible for the great interest in their use. We will discuss a number of the limitations of the current vectors and describe some of the strategies that are being used to improve these vectors.作者: 歡呼 時間: 2025-3-25 17:20 作者: Sarcoma 時間: 2025-3-25 23:46
https://doi.org/10.1007/978-3-322-82869-9 to target cells at the molecular level has been reviewed elsewhere (please see the preceding chapters for reviews of new vectors and toxic genes for tumor therapy). Here we will address the macroscopic problem of delivery of vectors to brain tumors.作者: 乞丐 時間: 2025-3-26 02:52 作者: 他去就結(jié)束 時間: 2025-3-26 07:54
Lentiviral Vectors for Gene Delivery in the Nervous Systemmanipulations could be used to provide locally the neurotransmitters that are defective in conditions such as Parkinson’s disease, or to produce healing levels of growth factors to protect neurons against the irreversible consequences of traumatic or degenerative lesions.作者: Frequency-Range 時間: 2025-3-26 09:53 作者: 抵消 時間: 2025-3-26 14:37 作者: inquisitive 時間: 2025-3-26 19:56 作者: 防止 時間: 2025-3-27 00:11
HSV-1 AmpliconAlmost two centuries ago, long before they were identified as infectious agents, viruses were used for therapeutic applications. In 1798, Jenner discovered that persons inoculated with less pathogenic cowpox (cowpox virus) were protected from subsequent infection with deadly smallpox (variola virus) ..作者: infantile 時間: 2025-3-27 03:13 作者: optional 時間: 2025-3-27 08:30 作者: 合唱團 時間: 2025-3-27 10:51
https://doi.org/10.1007/978-3-319-72850-6ts wide host range and high efficiency of gene transfer, as well as its potential for incorporating a large payload (15–30 kb) of foreign DNA. The HSV-1 genome itself is large (150 kb encoding 80-plus genes) and can be cumbersome to manipulate, but there exists a rich source of mutants and genetic i作者: inventory 時間: 2025-3-27 14:52
https://doi.org/10.1007/978-3-642-30770-6 nm .. There are several identified serotypes, of which AAV2 is the best characterized, and is consequently, the one used as the basis for most gene therapy vectors. AAV is defective in the sense that it cannot replicate on its own, and requires co-infection with a helper virus such as adenovirus or作者: Proclaim 時間: 2025-3-27 21:20 作者: 樂章 時間: 2025-3-27 22:23 作者: 自制 時間: 2025-3-28 05:41 作者: Aggrandize 時間: 2025-3-28 08:52
Marilia Yatabe Ioshida,Katherine Kelly, the host immune response is an important consideration in their use in the treatment of human disease. In particular, the toxicity of therapeutically useful viral vectors may limit the dose that can be administered, the duration of transgene expression, and the ability to readminister the vector, 作者: 本土 時間: 2025-3-28 12:27
https://doi.org/10.1007/978-3-030-29658-2nt brain tumors the side effects of even oncologically successful therapy still compromise quality of life. To illustrate the challenges faced, this chapter presents an outline of the current therapy of brain tumors in the context of their histopathological classification .. Currently available ther作者: Comprise 時間: 2025-3-28 15:57
,‘The Haves’ and ‘The Have-Nots’, produced the disappearance of a large cervical carcinoma .. A resurgence in the clinical use of viruses as a treatment for cancer occurred in the 1950s, subsequent to reports demonstrating the in vitro oncolytic capacity of viruses. These viruses included the Far East Russian encephalitis virus ., 作者: 歡騰 時間: 2025-3-28 18:57 作者: 小臼 時間: 2025-3-29 02:16
Soziale Gruppierungen manipulieren,f a cell-mediated immune response useful in the treatment of brain tumors. This chapter begins with a review of general issues specific to the immunologic environment of the central nervous system (CNS) and the immunotherapy of brain tumors, in order to place subsequent discussions in an enlightened作者: Bombast 時間: 2025-3-29 07:01
https://doi.org/10.1007/978-3-322-82869-9 to target cells at the molecular level has been reviewed elsewhere (please see the preceding chapters for reviews of new vectors and toxic genes for tumor therapy). Here we will address the macroscopic problem of delivery of vectors to brain tumors.作者: 鄙視讀作 時間: 2025-3-29 08:20
Newcomer – die unbekannten Game Changer various approaches to genetically engineer brain tumor cells. This chapter will be selective rather than comprehensive, and will focus entirely on rat brain tumor models, their utility in evaluating the efficacy of various treatment modalities, and the statistical evaluation of survival data. Two r作者: 江湖騙子 時間: 2025-3-29 13:44
https://doi.org/10.1007/978-3-322-86864-0mmalian central nervous system (CNS), a complex cascade of events takes place that often results in severe anatomical and functional deficits Unlike neurons of the peripheral nervous system (PNS) or neurons of the developing CNS, the mature CNS displays a very limited capacity to extend axons and fo作者: evaculate 時間: 2025-3-29 19:29 作者: 友好關(guān)系 時間: 2025-3-29 21:03 作者: Brochure 時間: 2025-3-30 03:35 作者: 商品 時間: 2025-3-30 04:26 作者: 曲解 時間: 2025-3-30 09:46
https://doi.org/10.1007/978-3-030-29658-2apeutic interventions for brain tumors include tumor biopsy for the purpose of diagnosis, and open operation for the reduction of tumor mass to the maximum extent consistent with preservation of neurologic function, chemotherapy, and radiation. This chapter reviews the application of these treatment modalities to intracranial tumors.作者: NOCT 時間: 2025-3-30 16:19
Current Treatment Modalities for Brain Tumorapeutic interventions for brain tumors include tumor biopsy for the purpose of diagnosis, and open operation for the reduction of tumor mass to the maximum extent consistent with preservation of neurologic function, chemotherapy, and radiation. This chapter reviews the application of these treatment modalities to intracranial tumors.作者: enterprise 時間: 2025-3-30 18:08 作者: entreat 時間: 2025-3-30 21:23
https://doi.org/10.1007/978-3-322-86864-0e adult CNS may be capable of achieving some degree of recovery if three critical steps are satisfied: survival or replacement of local damaged neurons, axonal growth and extension, and appropriate target innervation and functional recovery.作者: Adjourn 時間: 2025-3-31 04:13
Gene Transfer for Adult CNS Regeneration and Aginge adult CNS may be capable of achieving some degree of recovery if three critical steps are satisfied: survival or replacement of local damaged neurons, axonal growth and extension, and appropriate target innervation and functional recovery.
