標(biāo)題: Titlebook: Gene Regulatory Sequences and Human Disease; Nadav Ahituv Book 2012 Springer Science+Business Media, LLC 2012 Systems Biology [打印本頁(yè)] 作者: 欺侮 時(shí)間: 2025-3-21 17:08
書(shū)目名稱Gene Regulatory Sequences and Human Disease影響因子(影響力)
書(shū)目名稱Gene Regulatory Sequences and Human Disease影響因子(影響力)學(xué)科排名
書(shū)目名稱Gene Regulatory Sequences and Human Disease網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Gene Regulatory Sequences and Human Disease網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Gene Regulatory Sequences and Human Disease被引頻次
書(shū)目名稱Gene Regulatory Sequences and Human Disease被引頻次學(xué)科排名
書(shū)目名稱Gene Regulatory Sequences and Human Disease年度引用
書(shū)目名稱Gene Regulatory Sequences and Human Disease年度引用學(xué)科排名
書(shū)目名稱Gene Regulatory Sequences and Human Disease讀者反饋
書(shū)目名稱Gene Regulatory Sequences and Human Disease讀者反饋學(xué)科排名
作者: chiropractor 時(shí)間: 2025-3-21 23:13
Marina Metz,Olga Skriabina,Anna Samokhvalova can lead to human disease. In this chapter, we will define the different types of gene regulatory elements (promoters, enhancers, silencers, and insulators) and how to identify and functionally characterize them.作者: 滔滔不絕地說(shuō) 時(shí)間: 2025-3-22 04:28 作者: 盲信者 時(shí)間: 2025-3-22 04:51 作者: 珠寶 時(shí)間: 2025-3-22 11:54 作者: iodides 時(shí)間: 2025-3-22 16:32
gical advances that led to this breakthrough. In addition, several examples will be provided of nucleotide variants in noncoding sequences that have been shown to be associated with various human diseases.978-1-4899-8785-3978-1-4614-1683-8作者: iodides 時(shí)間: 2025-3-22 18:28
Literatur der russischen Emigrant/innen cause dramatic changes to patterning, leading to congenital limb malformations. In this chapter, we will review characterized gene regulatory mutations leading to human limb malformations and also provide evidence that additional limb enhancers could be the cause of other human limb malformations.作者: Texture 時(shí)間: 2025-3-22 21:16
,-Regulatory Enhancer Mutations are a Cause of Human Limb Malformations, cause dramatic changes to patterning, leading to congenital limb malformations. In this chapter, we will review characterized gene regulatory mutations leading to human limb malformations and also provide evidence that additional limb enhancers could be the cause of other human limb malformations.作者: 秘方藥 時(shí)間: 2025-3-23 05:14 作者: 財(cái)主 時(shí)間: 2025-3-23 07:58
Interkulturelle Medienkommunikationst a requirement for craniofacial-specific regulatory elements during . transcription in embryonic development and how the .-ruption of these elements alone might result in isolated PRS, an endophenotype of CD.作者: LIMN 時(shí)間: 2025-3-23 10:20 作者: 迅速飛過(guò) 時(shí)間: 2025-3-23 17:51 作者: 緊張過(guò)度 時(shí)間: 2025-3-23 19:37 作者: 兩棲動(dòng)物 時(shí)間: 2025-3-23 22:37
The Contributions of , Noncoding Variation to Hirschsprung Disease,tral player in the development of HSCR, most frequently modified in effect by the contributions of risk alleles at other loci. This has been exemplified by the recent characterization of risk variants in a noncoding . regulatory element, establishing it as a model for the study of multigenic disorders.作者: transient-pain 時(shí)間: 2025-3-24 04:11 作者: 高歌 時(shí)間: 2025-3-24 10:33 作者: adipose-tissue 時(shí)間: 2025-3-24 11:57 作者: 咒語(yǔ) 時(shí)間: 2025-3-24 16:51
Gene Regulatory Elements, still remains primarily uncharted territory. Within this territory reside gene regulatory sequences that instruct genes when, where, and at what levels to turn on or off. There is abundant evidence, as described in this book, that nucleotide and epigenetic changes in these gene regulatory sequences作者: 欲望小妹 時(shí)間: 2025-3-24 19:23
The Hemoglobin Regulatory Regions,ne clusters direct the production of hemoglobin including the α-locus which contains the embryonic ζ gene and two adult α genes on chromosome 16. A second cluster, the β-globin locus located on chromosome 11, contains the ε, .γ, .γ, δ, and β genes. The globin genes are arranged from 5′ to 3′ accordi作者: 豐滿有漂亮 時(shí)間: 2025-3-25 01:41 作者: convulsion 時(shí)間: 2025-3-25 03:25 作者: Heterodoxy 時(shí)間: 2025-3-25 10:15
,-Regulatory Enhancer Mutations are a Cause of Human Limb Malformations,le it is known that some limb malformations are the result of coding mutations that disrupt genes, identifying the causal mutation in a patient with an isolated limb malformation is often difficult. This may be due in part to the growing number of cases with isolated limb malformations that are show作者: BRAVE 時(shí)間: 2025-3-25 12:17
Regulatory Mutations Leading to Cleft Lip and Palate,cted individual, their families, and society provides strong motivation to understand the causes. Initial genetic studies focused on coding regions of genes that are required for normal development of the lip and palate. However, many individuals with cleft lip and palate do not have mutations in th作者: abracadabra 時(shí)間: 2025-3-25 19:36 作者: 果核 時(shí)間: 2025-3-25 23:24 作者: 過(guò)多 時(shí)間: 2025-3-26 00:31
The Contributions of , Noncoding Variation to Hirschsprung Disease,he absence of variable length of the submucous (Meissner’s) and myenteric (Auerbach’s) plexuses in the distal gut. As a defect in neural crest-derived cell population, Hirschsprung disease is considered a neurocristopathy. While HSCR was originally observed in sporadic cases, the advent of lifesavin作者: Infelicity 時(shí)間: 2025-3-26 07:35 作者: 高談闊論 時(shí)間: 2025-3-26 11:49
Cohesin and Human Diseases,ys essential cellular functions in sister chromatid cohesion during mitosis and meiosis, DNA repair, gene expression, and maintaining 3-D genome organization. Cohesin is required for cell division, maintaining pluripotency of stem cells and ensuring normal organ development. Defective cohesin genes 作者: 吹牛者 時(shí)間: 2025-3-26 14:44 作者: FLEET 時(shí)間: 2025-3-26 17:52 作者: 脾氣暴躁的人 時(shí)間: 2025-3-26 23:45 作者: 行業(yè) 時(shí)間: 2025-3-27 02:20
Verwaltungskultur im Ausl?nderamtof fragility fracture. Genetic factors play an important role in regulating bone mineral density (BMD) and other phenotypes relevant to the pathogenesis of osteoporosis. It is currently believed that a large number of susceptibility alleles contribute to the risk of osteoporosis each with a small ef作者: 騷動(dòng) 時(shí)間: 2025-3-27 07:13 作者: 玉米 時(shí)間: 2025-3-27 11:12 作者: 生命層 時(shí)間: 2025-3-27 15:08
,Interkulturalit?t: Terminologische Aspekte,cted individual, their families, and society provides strong motivation to understand the causes. Initial genetic studies focused on coding regions of genes that are required for normal development of the lip and palate. However, many individuals with cleft lip and palate do not have mutations in th作者: FIN 時(shí)間: 2025-3-27 19:35 作者: transdermal 時(shí)間: 2025-3-28 00:37
Forschung Erziehungswissenschaftrldwide (WHO 2010). The etiology of hearing loss is varied and can include environmental noise, physical trauma to the head, infections, ototoxic compounds, and the natural aging process. Heritable hearing loss segregating as a Mendelian trait is thought to constitute but a fraction of cases; noneth作者: 外表讀作 時(shí)間: 2025-3-28 04:16
,Lehren für eine bunte Republik?,he absence of variable length of the submucous (Meissner’s) and myenteric (Auerbach’s) plexuses in the distal gut. As a defect in neural crest-derived cell population, Hirschsprung disease is considered a neurocristopathy. While HSCR was originally observed in sporadic cases, the advent of lifesavin作者: 裙帶關(guān)系 時(shí)間: 2025-3-28 07:13 作者: lesion 時(shí)間: 2025-3-28 12:46
Ich habe meinen Anwalt bei mir …ys essential cellular functions in sister chromatid cohesion during mitosis and meiosis, DNA repair, gene expression, and maintaining 3-D genome organization. Cohesin is required for cell division, maintaining pluripotency of stem cells and ensuring normal organ development. Defective cohesin genes 作者: 羊欄 時(shí)間: 2025-3-28 15:39 作者: 預(yù)感 時(shí)間: 2025-3-28 22:10
The Hemoglobin Regulatory Regions,es of naturally occurring globin gene promoter mutations and transgenic mouse investigations have contributed to our understanding of the effect of DNA mutations on globin gene expression. Furthermore, the developmental regulation of globin gene expression has shaped research efforts to establish th作者: 多產(chǎn)子 時(shí)間: 2025-3-29 00:27 作者: EVADE 時(shí)間: 2025-3-29 05:09 作者: 卡死偷電 時(shí)間: 2025-3-29 08:16 作者: 災(zāi)難 時(shí)間: 2025-3-29 13:41
,-Regulatory Variation and Cancer,ighlighting risk variants in non-genic regions. Here, we highlight examples of cancer-associated variation in promoters, enhancers, and silencers, as well as changes to the overall architecture of a gene’s regulatory landscape. These functional characterizations bring us closer to understanding the 作者: bizarre 時(shí)間: 2025-3-29 16:26 作者: 使成波狀 時(shí)間: 2025-3-29 20:45 作者: 解開(kāi) 時(shí)間: 2025-3-30 03:51 作者: NOT 時(shí)間: 2025-3-30 05:06
,Interkulturalit?t: Terminologische Aspekte,ression of ., a gene that is required for development of both the lip and the palate. Second, a DNA variant in a sequence that is 1.5 Mb away from the . gene exemplifies the discovery and validation of a long-range enhancer element. This chapter also contains brief discussions of other examples of D作者: Critical 時(shí)間: 2025-3-30 10:07
