標(biāo)題: Titlebook: Gene Delivery to Mammalian Cells; Volume 2: Viral Gene William C. Heiser Book 2004 Humana Press 2004 [打印本頁] 作者: 矜持 時(shí)間: 2025-3-21 17:29
書目名稱Gene Delivery to Mammalian Cells影響因子(影響力)
書目名稱Gene Delivery to Mammalian Cells影響因子(影響力)學(xué)科排名
書目名稱Gene Delivery to Mammalian Cells網(wǎng)絡(luò)公開度
書目名稱Gene Delivery to Mammalian Cells網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Gene Delivery to Mammalian Cells被引頻次
書目名稱Gene Delivery to Mammalian Cells被引頻次學(xué)科排名
書目名稱Gene Delivery to Mammalian Cells年度引用
書目名稱Gene Delivery to Mammalian Cells年度引用學(xué)科排名
書目名稱Gene Delivery to Mammalian Cells讀者反饋
書目名稱Gene Delivery to Mammalian Cells讀者反饋學(xué)科排名
作者: abstemious 時(shí)間: 2025-3-21 22:47 作者: MOTIF 時(shí)間: 2025-3-22 03:06 作者: Foam-Cells 時(shí)間: 2025-3-22 05:59 作者: 太空 時(shí)間: 2025-3-22 12:30 作者: Anecdote 時(shí)間: 2025-3-22 14:49 作者: Anecdote 時(shí)間: 2025-3-22 20:20 作者: 一大塊 時(shí)間: 2025-3-23 00:39
Professional Response to Child Sexual Abuse vivo is now the milestone for gene therapy to succeed against disseminated cancer. Therefore, most valuable information is obtained from studies of vector biodistribution. Owing to the hepatotropism of adenoviral vectors, a particularly important parameter is the tumor/liver ratio. This ratio can b作者: sphincter 時(shí)間: 2025-3-23 04:38
https://doi.org/10.1007/978-1-349-19270-0 to mount a specific cellular and humoral response. Recognition of this crucial function makes the development of technologies for DC-based immuno-therapies a priority for the treatment of a wide variety of diseases. The most immediate impact of this emerging technology will be in the treatment of c作者: Hamper 時(shí)間: 2025-3-23 08:17
Geetanjali Gangoli,Marianne Hesterticularly useful for applications where sustained gene expression is required. Prolonged in vivo expression following A AV treatment has been seen in the liver (.,.), brain (.,.), skeletal muscle (.,.), lung (.,.), and hematopoietic stem cells (.,.) of animal models. Therapeutic benefit from A AV tr作者: endoscopy 時(shí)間: 2025-3-23 12:43
https://doi.org/10.1007/978-3-642-23614-3uman diseases. AAV’s inability to self-propagate, ability to be maintained as an episome in the transduced cell, and relatively innocuous effects on the immune system make it the vector of choice for prolonged in vivo gene expression. AAV type 2 is the most commonly used serotype for gene delivery. 作者: PHONE 時(shí)間: 2025-3-23 17:11
Research Design and Methodology,AAV vectors are devoid of viral-coding sequences and may efficiently transfer genes to nondividing cells such as muscle fibers or hepatocytes following in vivo transduction (.–.). Recombinant AAV can be administered to skeletal muscle of experimental animals and, as recently documented in a Phase I 作者: 沙漠 時(shí)間: 2025-3-23 21:44
https://doi.org/10.1007/978-3-030-20663-5ere prolonged expression of genes in the liver is required, adeno-associated virus (AAV) has proven to be an effective tool for in vivo gene transfer. High-level, persistent hepatic expression has been achieved in a number of experimental systems following a single treatment with AAV in murine and l作者: 共棲 時(shí)間: 2025-3-24 01:43
Alpaslan ?zerdem,Sukanya Podder(.–.) makes them excellent tools for gene transfer. One tissue of interest for gene transfer is the lung epithelium, which is afflicted in cystic fibrosis (CF). However, although initial animal studies done with vectors based on A AV type 2 have demonstrated transduction in multiple cells types in t作者: 條約 時(shí)間: 2025-3-24 02:48
Brett Pierce,Christabel Kalaiselvischemic heart disease, and cardiomyopathy. In addition to its potential for treatment of disease, myocardial gene transfer is useful for the analysis of gene expression and promoter function and for generating animal models of human disease such as pulmonary hypertension. The ideal vector for myocar作者: 繞著哥哥問 時(shí)間: 2025-3-24 09:40 作者: catagen 時(shí)間: 2025-3-24 12:29
John Cockburn,Jane Kabubo-Mariarad with those that have been published on targeting normal cells. A major reason for this can be attributed to the biology of the vector itself. AAV, being a nonpathogenic vector capable of providing transgene integration and long-term expression, is ideally suited for the correction of metabolic def作者: Trabeculoplasty 時(shí)間: 2025-3-24 16:27
Gene Delivery to Mammalian Cells978-1-59259-650-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: interpose 時(shí)間: 2025-3-24 22:08 作者: 矛盾心理 時(shí)間: 2025-3-25 00:17
Gene Delivery to the Mouse Brain with Adeno-Associated Virusutic genes to the mammalian brain. An attractive feature of AAV is that all the viral-coding sequences are removed when engineering the recombinant genome, thereby limiting the extent of cell toxicity and immune response that are often associated with viral gene transcription (.).作者: 不怕任性 時(shí)間: 2025-3-25 06:08 作者: 無聊的人 時(shí)間: 2025-3-25 10:14
https://doi.org/10.1007/978-981-16-8181-3 to qualitatively evaluate liver transduction efficiency following delivery of an adenoviral vector encoding a β-galactosidase (β-gal) marker gene. Additionally, several alternative methods to verify efficient liver transduction are introduced.作者: Gesture 時(shí)間: 2025-3-25 12:34
Professional Response to Child Sexual Abuseing animals. We present a radioactive labeling method that can be used to study biodistribution. After a small section dealing with tumor models, we describe methods to quantify different parameters related to adenovirus-mediated tumor targeting.作者: myopia 時(shí)間: 2025-3-25 15:57
https://doi.org/10.1007/978-3-642-23614-3ate proteoglycan (.), α.β. integrin (.) and the fibroblast growth factor receptor-1 (FGFR-1) (.) are believed to mediate the initial internalization steps in infection. The ubiquity of these cell-surface components confers a wide tropism on AAV2 vectors.作者: 艱苦地移動 時(shí)間: 2025-3-25 23:17 作者: 閑逛 時(shí)間: 2025-3-26 03:54
Brett Pierce,Christabel Kalaiselvion can be obtained with adenovirus vectors, immune responses and elimination of transduced cells results in only transient expression in immunocompetent hosts. Vectors based on recombinant adeno-associated virus (rAAV) offer a number of attractive features and are emerging as promising gene transfer vehicles for many in vivo applications.作者: semble 時(shí)間: 2025-3-26 06:15 作者: 隱語 時(shí)間: 2025-3-26 09:46
Adenovirus-Mediated Gene Transfer to Tumor Cellsing animals. We present a radioactive labeling method that can be used to study biodistribution. After a small section dealing with tumor models, we describe methods to quantify different parameters related to adenovirus-mediated tumor targeting.作者: Synapse 時(shí)間: 2025-3-26 16:16 作者: 接合 時(shí)間: 2025-3-26 17:50 作者: nephritis 時(shí)間: 2025-3-26 21:33
Gene Delivery to the Mammalian Heart Using AAV Vectorson can be obtained with adenovirus vectors, immune responses and elimination of transduced cells results in only transient expression in immunocompetent hosts. Vectors based on recombinant adeno-associated virus (rAAV) offer a number of attractive features and are emerging as promising gene transfer vehicles for many in vivo applications.作者: 雪白 時(shí)間: 2025-3-27 04:21
1064-3745 st shown to be capable of enhancing transfer of RNA into mammalian cells in culture. Not only have other chemical methods been developed and refined, but also very efficient physical and viral delivery methods have been established. The technique of introducing DNA into cells has developed from tran作者: 提名的名單 時(shí)間: 2025-3-27 07:54
Child Refugee Asylum as a Basic Human Rightange of mammalian species. Human adenoviruses are classified into six subgroups based on the percentage of guanine and cytosine in the DNA molecules and the ability to agglutinate red blood cells. They are further subdivided into more than 50 serotypes, primarily on the basis of neutralization assays (reviewed in ..).作者: 廣大 時(shí)間: 2025-3-27 11:32 作者: 可憎 時(shí)間: 2025-3-27 15:17
https://doi.org/10.1007/978-3-030-20663-5ism, where lifelong expression of the deficient enzyme may be required. Therapeutic benefits using AAV vectors have been demonstrated in animal models of amino acid disorders, lysosomal storage diseases, and coagulopathies (.–.), and Phase I clinical trials are proposed for the treatment of hemophilia B (.).作者: molest 時(shí)間: 2025-3-27 19:34 作者: 破譯密碼 時(shí)間: 2025-3-27 22:59 作者: Inoperable 時(shí)間: 2025-3-28 04:35 作者: ICLE 時(shí)間: 2025-3-28 08:16 作者: lipids 時(shí)間: 2025-3-28 13:12 作者: CUR 時(shí)間: 2025-3-28 18:02
Delivery of DNA to Lung Airway Epitheliumion of epithelial cells (.–.). Much current work in lung gene therapy is directed toward overcoming the inflammatory and immune responses provoked by gene-transfer vectors while simultaneously maximizing vector delivery and subsequent gene expression.作者: 爭論 時(shí)間: 2025-3-28 19:39
Delivery of DNA to Tumor Cells In Vivo Using Adeno-Associated Virusects either to replace a defective protein/enzyme or to elevate their otherwise suboptimal levels in the system. However, increased understanding of both the biology of tumor progression and potential utility of AAV-based vectors suggests that this vector can also be wisely used for cancer gene therapy.作者: Decibel 時(shí)間: 2025-3-28 23:14
Adenovirus-Mediated Gene Deliveryange of mammalian species. Human adenoviruses are classified into six subgroups based on the percentage of guanine and cytosine in the DNA molecules and the ability to agglutinate red blood cells. They are further subdivided into more than 50 serotypes, primarily on the basis of neutralization assays (reviewed in ..).作者: 卡死偷電 時(shí)間: 2025-3-29 07:01
Adenovirus-Mediated Gene Deliveryiruses constitute the . family, which is divided into two genera: the . genus infects only birds, whereas the . genus contains viruses that infect a range of mammalian species. Human adenoviruses are classified into six subgroups based on the percentage of guanine and cytosine in the DNA molecules a作者: 充氣球 時(shí)間: 2025-3-29 08:08 作者: Urea508 時(shí)間: 2025-3-29 15:02
Adenovirus-Mediated Gene Delivery to Skeletal Muscledenoviral vectors awaits the development of methods to allow safe and efficient targeted gene delivery to mature skeletal muscle upon intravenous vector administration (.), the current generation of vectors has nonetheless found utility in preclinical studies of gene therapy and in gene-transfer exp作者: Arteriography 時(shí)間: 2025-3-29 17:50 作者: appall 時(shí)間: 2025-3-29 22:39 作者: grounded 時(shí)間: 2025-3-30 00:08 作者: gratify 時(shí)間: 2025-3-30 05:01
Gene Transfer to Brain and Spinal Cord Using Recombinant Adenoviral Vectorscause respiratory and gastrointestinal infections. Forty-three different human adenovirus serotypes have been characterized (.). Details about production of recombinant Ad vectors are given in .. Ad vectors in widespread use are derived from human Ad serotypes 2 and 5 (Ad2 and Ad5), Ad5 being more c作者: Living-Will 時(shí)間: 2025-3-30 11:35 作者: Recess 時(shí)間: 2025-3-30 12:52
Adenovirus-Mediated Gene Delivery to Dendritic Cells to mount a specific cellular and humoral response. Recognition of this crucial function makes the development of technologies for DC-based immuno-therapies a priority for the treatment of a wide variety of diseases. The most immediate impact of this emerging technology will be in the treatment of c作者: 清澈 時(shí)間: 2025-3-30 18:36
Overview of Adeno-Associated Viral Vectorsticularly useful for applications where sustained gene expression is required. Prolonged in vivo expression following A AV treatment has been seen in the liver (.,.), brain (.,.), skeletal muscle (.,.), lung (.,.), and hematopoietic stem cells (.,.) of animal models. Therapeutic benefit from A AV tr作者: GAVEL 時(shí)間: 2025-3-31 00:11
AAV Vector Delivery to Cells in Cultureuman diseases. AAV’s inability to self-propagate, ability to be maintained as an episome in the transduced cell, and relatively innocuous effects on the immune system make it the vector of choice for prolonged in vivo gene expression. AAV type 2 is the most commonly used serotype for gene delivery. 作者: 熔巖 時(shí)間: 2025-3-31 04:15
