標(biāo)題: Titlebook: Gene Delivery; Huayu Tian,Xuesi Chen Living reference work 20210th edition Gene carriers.Gene therapy.Antitumor.Gene editing.Cationic pol [打印本頁] 作者: 吸收 時(shí)間: 2025-3-21 17:44
書目名稱Gene Delivery影響因子(影響力)
書目名稱Gene Delivery影響因子(影響力)學(xué)科排名
書目名稱Gene Delivery網(wǎng)絡(luò)公開度
書目名稱Gene Delivery網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Gene Delivery被引頻次
書目名稱Gene Delivery被引頻次學(xué)科排名
書目名稱Gene Delivery年度引用
書目名稱Gene Delivery年度引用學(xué)科排名
書目名稱Gene Delivery讀者反饋
書目名稱Gene Delivery讀者反饋學(xué)科排名
作者: geometrician 時(shí)間: 2025-3-21 21:50
The Entire Guard Followed Pravyk,lar strategy to drive the assembly of peptide dendrimers and polypeptides into capsid-like nanoparticles (CLNs) for gene delivery. Low-generation poly(L-lysine) dendrimers and glutamic acid-functionalized polypeptides can assemble into dendritic supramolecular amphiphiles via supramolecular interact作者: 慢跑 時(shí)間: 2025-3-22 00:41 作者: 使困惑 時(shí)間: 2025-3-22 05:04
https://doi.org/10.1007/978-1-4613-9311-5owever, delivering the considerable concentration of right molecule to the desired cells or tissues and overcome multidrug resistance (MDR) are challenging tasks in gene therapy. To date, several viral and nonviral vectors for gene delivery systems have been developed and possess some serious unreso作者: Irksome 時(shí)間: 2025-3-22 10:32
Radiation Dose and Imaging Protocols,py. Therapeutic gene was condensed by polycation polyethylenimine (PEI) and polyanion poly-.-glutamate (PLG), further in situ tightened by aldehyde-modified polyethylene glycol (PEG) via Schiff-base reaction. The Schiff-base bonds were stable in neutral physiological pH but cleavable in acidic tumor作者: 骨 時(shí)間: 2025-3-22 12:55 作者: 骨 時(shí)間: 2025-3-22 18:21 作者: Infusion 時(shí)間: 2025-3-22 23:19
Chest Pain with Normal Coronary Arterieses and cationic polymers are unstable because of their weak electrostatic interactions, resulting in polymer/nucleic acid polyplexes with poor serum resistance and a short circulation time in vivo. Furthermore, most polymer/nucleic acid polyplexes mixture exhibit high toxicity because an excess of h作者: 撫慰 時(shí)間: 2025-3-23 02:39
Sonja Beckh,Gebhard Mathis,Christian G?rgities. In this section, we demonstrated a molecular and supramolecular approach of arginine-rich nanohybrids (ARNHs) based on coassembly of low-generation dendrimers and inorganic nanoparticles for visible gene delivery. Arginine-rich corona of ARNHs provided efficient DNA-binding ability, high inte作者: falsehood 時(shí)間: 2025-3-23 07:31
Giovanni Volpicelli,Luna Gargani. Polycationic gene carriers have attracted increasing attention due to non-immunogenicity, easy manufacture, and flexible properties. However, high transfection efficiency and low cytotoxicity is a dilemma in the design of polycationic gene carriers. In this chapter, a simple and versatile strategy作者: 使虛弱 時(shí)間: 2025-3-23 12:56 作者: nutrients 時(shí)間: 2025-3-23 16:30
Felix J. F. Herth,Ralf Eberhardtucleic acid–based therapeutics, including plasmid DNA (pDNA), small interfering RNA (siRNA), messenger RNA (mRNA), micro-RNA (miRNA), and CRISPR/Cas, have entered different phases of clinical trials. However, in vivo delivery of this class of drugs has encountered various obstacles, especially endo/作者: 柏樹 時(shí)間: 2025-3-23 18:00
Injuries to the Heart by Blunt Traumacancer treatment. Co-delivery of chemotherapy drugs and small interfering RNA (siRNA) through advanced nanotechnology provides a reliable and effective strategy for combination therapy with synergistic effect. In this regard, this protocol focuses on the fabrication of polypeptide cationic micelles 作者: 暴發(fā)戶 時(shí)間: 2025-3-24 01:34 作者: 原來 時(shí)間: 2025-3-24 03:21 作者: harbinger 時(shí)間: 2025-3-24 07:38 作者: Graves’-disease 時(shí)間: 2025-3-24 13:38
Radiological Assessment of Pain in the Foote expression at the transcriptional level without causing damage to genomic DNA, providing a safer and natural tool to treat cancers. However, due to the conflicting surface requirements for different delivery stages, the development of drug delivery system for CRISPR/dCas9-based cancer gene therapy作者: Magisterial 時(shí)間: 2025-3-24 18:42 作者: 口味 時(shí)間: 2025-3-24 22:03 作者: 隱士 時(shí)間: 2025-3-25 00:39
https://doi.org/10.1007/978-3-319-70818-8d and programmed manner inside cells. In this regard, a new concept of reduction-controlled hierarchical unpacking is proposed for developing a virus-mimicking gene delivery system. This protocol describes the fabrications of the reduction-controlled hierarchical unpacking terplexes based on the dis作者: Adulate 時(shí)間: 2025-3-25 06:28 作者: hermitage 時(shí)間: 2025-3-25 11:29
Huayu Tian,Xuesi ChenServes as an everyday reference for scientists, practitioners and students in gene delivery.Presents recent developments of nanoparticles for clinical gene therapy.Employs a systematic approach offeri作者: AWE 時(shí)間: 2025-3-25 14:54
2523-8809 r clinical gene therapy.Employs a systematic approach offeriGene therapy has been regarded as a great potential for specific treatment of gene-related human diseases, such as cancer, genetic and epidemic diseases. Gene therapy refers to the biomedical technology that inserts normal or therapeutic ex作者: caldron 時(shí)間: 2025-3-25 18:50
Living reference work 20210th editiones. Gene therapy refers to the biomedical technology that inserts normal or therapeutic exogenous genes into target cells to repair or replace defective genes in target cells, so as to achieve the purpose of treating diseases. Efficient gene delivery systems are the crucial roles for successful impl作者: Commonwealth 時(shí)間: 2025-3-25 21:54 作者: bourgeois 時(shí)間: 2025-3-26 03:50 作者: Instantaneous 時(shí)間: 2025-3-26 07:22 作者: 音的強(qiáng)弱 時(shí)間: 2025-3-26 11:34 作者: Arthr- 時(shí)間: 2025-3-26 12:44
Chiang Kaishek‘s Last Ambassador to Moscow internalized siRNA. We elaborately described the synthesis of the polymer, preparation, and characterization of the siRNA-loaded nanoparticles, the process of internalization and intracellular trafficking of nanoparticles, as well as . and . gene silencing and cancer treatment effects of proposed organic nanoformulation.作者: 整頓 時(shí)間: 2025-3-26 19:10 作者: 可轉(zhuǎn)變 時(shí)間: 2025-3-26 21:23 作者: 連鎖,連串 時(shí)間: 2025-3-27 03:44
Molecular and Supramolecular Construction of Arginine-Rich Nanohybrids for Visible Gene Delivery, gene delivery and monitor protein expression. In vitro and in vivo results demonstrated that the ARNHs exhibited high gene transfection efficiency, good biocompatibility, facile fabrication, and real-time bioimaging capabilities.作者: HACK 時(shí)間: 2025-3-27 07:04 作者: macabre 時(shí)間: 2025-3-27 11:19
Preparation and Evaluation of Rationally Designed Polymers for Efficient Endosomal Escape of siRNA, internalized siRNA. We elaborately described the synthesis of the polymer, preparation, and characterization of the siRNA-loaded nanoparticles, the process of internalization and intracellular trafficking of nanoparticles, as well as . and . gene silencing and cancer treatment effects of proposed organic nanoformulation.作者: Petechiae 時(shí)間: 2025-3-27 15:14 作者: 上坡 時(shí)間: 2025-3-27 18:22
Bioreducible Zinc (II)-Coordinative Polyethylenimine with Low Molecular Weight for Robust Gene Delilogues, which can be cleaved by abundant glutathione in cytoplasm. The Zn coordination strategy dramatically enhances transfection efficacy of LMW cationic polymers across diverse cell types, including primary and stem cells.作者: Promotion 時(shí)間: 2025-3-28 01:13
Living reference work 20210th editionementation of gene therapy. This book provides a platform for young scholars and students to systematically understand the preparation and characterization of the existing non-viral gene delivery systems, as well as providing a technology platform for clinical gene therapy.作者: 無法解釋 時(shí)間: 2025-3-28 02:22
A Codelivery System of Anticancer Drug Doxorubicin and Tumor-Suppressor Gene p53 Based on Polyphosponic carrier can be respectively prepared through a combination of ring-opening polymerization (ROP) and “click” reaction. First, poly(ethylene glycol)monomethyl ether (mPEG) is used to initiate the ring-opening polymerization of a cyclic phosphoester monomer, 2-(but-3-yn-1-yloxy)-2-oxo-1,3,2-dioxap作者: 易怒 時(shí)間: 2025-3-28 08:34 作者: 相反放置 時(shí)間: 2025-3-28 10:39
Bioreducible Zinc (II)-Coordinative Polyethylenimine with Low Molecular Weight for Robust Gene Delitocol describes a zinc(II) coordinative strategy to transform common LMW cationic polymers to highly efficient and safe gene vehicles. LMW cationic polymers exhibit lower efficacy compared to their high molecular weight counterparts, largely attributed to weaker nucleic acid binding. From this point作者: 殺子女者 時(shí)間: 2025-3-28 16:36 作者: 作嘔 時(shí)間: 2025-3-28 19:53 作者: Facet-Joints 時(shí)間: 2025-3-29 01:55 作者: 漫不經(jīng)心 時(shí)間: 2025-3-29 06:45 作者: 放氣 時(shí)間: 2025-3-29 07:15 作者: 輕推 時(shí)間: 2025-3-29 13:52 作者: FIR 時(shí)間: 2025-3-29 15:58
Molecular Strings Modified Gene Delivery System,. Polycationic gene carriers have attracted increasing attention due to non-immunogenicity, easy manufacture, and flexible properties. However, high transfection efficiency and low cytotoxicity is a dilemma in the design of polycationic gene carriers. In this chapter, a simple and versatile strategy作者: minion 時(shí)間: 2025-3-29 23:24 作者: 健壯 時(shí)間: 2025-3-30 01:01
Peptide-Modified Polycations with Acid-Triggered Lytic Activity for Efficient Gene Delivery,ucleic acid–based therapeutics, including plasmid DNA (pDNA), small interfering RNA (siRNA), messenger RNA (mRNA), micro-RNA (miRNA), and CRISPR/Cas, have entered different phases of clinical trials. However, in vivo delivery of this class of drugs has encountered various obstacles, especially endo/作者: Biomarker 時(shí)間: 2025-3-30 05:06 作者: 漸變 時(shí)間: 2025-3-30 09:26 作者: LARK 時(shí)間: 2025-3-30 14:58
Preparation and Evaluation of Boronate-Linked Nanoassembly for Efficient Gene Delivery,combinational therapy in view of the rapid chemotherapeutic action. However, little attention has been paid to the “rapid” goal in vector-aided transfection process. This chapter describes a boronate-linked nanoassembly for the rapid transnuclear gene transport and efficient gene transfection in vit作者: 心神不寧 時(shí)間: 2025-3-30 19:56
Preparation and Evaluation of Lipopeptides with Arginine-Rich Periphery for Gene Delivery,ication. The present protocol focuses on synthesis, preparation, characterization of the gene carriers, including gene transfection efficiency evaluation as well as intracellular tracking. The synthesis of dendritic lipopeptides with bio-reducible disulfide linkage and dual aliphatic chains was firs作者: 極小量 時(shí)間: 2025-3-30 22:12
Preparation and Evaluation of Multistage Delivery Nanoparticle for Efficient CRISPR Activation In Ve expression at the transcriptional level without causing damage to genomic DNA, providing a safer and natural tool to treat cancers. However, due to the conflicting surface requirements for different delivery stages, the development of drug delivery system for CRISPR/dCas9-based cancer gene therapy作者: Minuet 時(shí)間: 2025-3-31 04:52
Preparation and Evaluation of Polymeric Hybrid Micelles to Co-Deliver Small Molecule Drug and siRNAecules to the cytoplasm of target cells still remains a huge challenge for the application in vivo. Here, this protocol describes a practical approach to prepare a highly flexible polymeric hybrid micelles for the in vivo delivery of siRNA. The micelles consist of cationic polycaprolactone-polyethyl作者: 銀版照相 時(shí)間: 2025-3-31 08:25
Preparation and Evaluation of Rationally Designed Polymers for Efficient Endosomal Escape of siRNA,e expression of any interest gene. However, delivery is the most complicated and challenging process that hampers the wide application of siRNA. Rapid and efficient escape of siRNA from endosome to cytoplasm constitutes a determinant factor for gene silencing. In this chapter, we provide a detailed 作者: Abominate 時(shí)間: 2025-3-31 09:17 作者: magnate 時(shí)間: 2025-3-31 15:14 作者: somnambulism 時(shí)間: 2025-3-31 17:37
Jim T. Smith,Nicholas A. Beresfordp of mPEG-.-PBYP and the azide group of DOX-.-N.. And the polycationic carrier (abbreviated as mPEG-.-PBYP-.-DAE) is obtained . the thiol-yne “click” reaction between mPEG-.-PBYP and 2-dimethylaminoethanethiol hydrochloride (DAE). The structures of mPEG-.-PBYP-.-DOX and mPEG-.-PBYP-.-DAE are charact作者: 阻撓 時(shí)間: 2025-3-31 22:16
