標題: Titlebook: Gastrointestinal Stromal Tumors; Bench to Bedside Charles R. Scoggins,Chandrajit P. Raut,John T. Mul Book 2017 Springer International Publi [打印本頁] 作者: MIFF 時間: 2025-3-21 20:09
書目名稱Gastrointestinal Stromal Tumors影響因子(影響力)
作者: Seminar 時間: 2025-3-21 23:53
Epidemiology of GIST,d by gain-of-function mutations in oncogenes, including . and . They are believed to arise from the interstitial cells of Cajal within the myenteric plexus of the gut. Many studies have characterized the incidence of GIST in the United States, Europe, and Asia. The annual incidence reported in the l作者: 舊石器時代 時間: 2025-3-22 02:03
Surgical Pathology of Gastrointestinal Stromal Tumors: Correlation with Clinical and Molecular Subtecularly heterogeneous group of tumors and the discovery of clinicopathologically distinct subtypes with critical implications for therapeutics, prognosis, and genetic counseling. Histomorphology, immunohistochemistry, and mutational analysis continue to play an exceedingly important role, not only 作者: chlorosis 時間: 2025-3-22 05:26
Inherited GIST,IT or PDGFRA, and not unexpectedly, GIST is a prominent feature in this inherited cancer predisposition syndrome called familial GIST. Patients with neurofibromatosis type 1 (NF1) have an increased risk of developing GIST with approximately 7 % of patients with NF1 developing GIST. The biology and t作者: 不確定 時間: 2025-3-22 09:20 作者: 孤僻 時間: 2025-3-22 15:08
Imaging and Response Evaluation of Gastrointestinal Stromal Tumors therapy for gastrointestinal stromal tumor (GIST). Often, GIST is detected incidentally during endoscopic procedures for unrelated cause, and endoscopic ultrasound with or without fine-needle aspiration aids in the diagnosis. Computed tomography (CT) with and without iodinated intravenous contrast 作者: 孤僻 時間: 2025-3-22 17:58
Endoscopic Evaluation of Gastrointestinal Stromal Tumors of the gastrointestinal tract from the distal esophagus to the anus, but they are most common in the stomach. The presence of c-KIT staining is a strong and universal marker of GISTs. Approximately 70 % patients with GISTs have some clinical symptoms, including gastrointestinal bleeding, manifested作者: BAIL 時間: 2025-3-23 00:27 作者: Fantasy 時間: 2025-3-23 03:52 作者: 易怒 時間: 2025-3-23 07:33
Minimally Invasive Approaches to Gastrointestinal Stromal Tumors (GISTs)then, laparoscopy has improved patient outcomes and transitioned through all surgical specialties, including general surgery thoracic, vascular, gynecology, and urology. Minimally invasive surgery has evolved since its creation due to improvements in instruments, visualization, hemostatsis, robotics作者: 良心 時間: 2025-3-23 12:00
Neoadjuvant Therapy and Surgical Consolidation for Localized Gastrointestinal Stromal Tumorssease that is locally advanced and either borderline resectable or unresectable. KIT inhibition by the oral drug imatinib is highly effective in most GISTs and can result in a measurable tumor shrinkage in a significant proportion of patients. Neoadjuvant therapy with imatinib has many potential adv作者: FAST 時間: 2025-3-23 15:17
Prognostic Factors for Advanced GISTematologic malignancies. The recognition of GIST as a separate entity from intestinal leiomyosarcomas laid the foundation for treatment of patients with advanced disease. GISTs are mesenchymal tumors of the intestinal tract originating from specialized nerve cells known as the interstitial cells of 作者: 輕信 時間: 2025-3-23 20:58 作者: chassis 時間: 2025-3-24 02:06 作者: LINE 時間: 2025-3-24 03:23
Management of Liver Metastases of Gastrointestinal Stromal Tumorsaggressively when possible. Combinations of tyrosine kinase inhibitors (TKIs) and aggressive surgical resection are current mainstays of therapy. Appropriate patient selection based on presentation and TKI response guides therapy. Salvage therapy may be possible for patients with GIST patients with 作者: 冷淡周邊 時間: 2025-3-24 07:20 作者: 議程 時間: 2025-3-24 14:00 作者: 凈禮 時間: 2025-3-24 17:57
Epidemiology of GIST,fic Islanders. The average age at diagnosis ranges from 62 to 75, with peak incidence in the 8th decade of life. In regard to tumor-related characteristics, the stomach is consistently the most common tumor location followed by the small intestine. Finally, risk factors associated with death include作者: lesion 時間: 2025-3-24 20:40 作者: 竊喜 時間: 2025-3-24 23:33 作者: Deference 時間: 2025-3-25 05:49 作者: 說明 時間: 2025-3-25 10:17
Endoscopic Management of Small GISTme data suggest a higher incidence of subclinical GISTs than had been previously thought. In one study, 100 whole stomachs were resected from patients with gastric cancer and examined for microscopic GISTs. They found 50 microscopic GISTs, all of which were positive for KIT and/or CD34 and negative 作者: crucial 時間: 2025-3-25 13:47
Minimally Invasive Approaches to Gastrointestinal Stromal Tumors (GISTs)ogic outcomes compared to open resection [1–8]. However, as with any operation for GIST, the adherence to oncologic surgical practices, including prevention of tumor spillage and appropriate resection, must be considered before deciding on a minimally invasive resection [1].作者: exigent 時間: 2025-3-25 17:57 作者: GUEER 時間: 2025-3-25 22:36
Prognostic Factors for Advanced GIST6, 2001), traditional chemotherapy agents failed usually causing stable disease at best without improvement of progression-free or overall survival (OS) (Edmonson et al., Cancer Invest 20(5–6):605–612, 2002; Blay et al., Eur J Cancer 40(9):1327–1331, 2004; Trent et al., Cancer 98(12):2693–2699, 2003作者: 一個姐姐 時間: 2025-3-26 01:56 作者: 猛然一拉 時間: 2025-3-26 05:02 作者: 僵硬 時間: 2025-3-26 12:25 作者: emission 時間: 2025-3-26 14:36 作者: 吊胃口 時間: 2025-3-26 19:56
Hermann Haken,Hans Christoph Wolfonography-guided fine-needle aspiration (EUS-FNA) for biopsy of GISTs is better than any other well-accepted method. The EUS-guided Tru-cut core biopsy technique provides a grossly visible sample of tissue, but it has some technical disadvantages. The curative treatment of GISTs is still complete su作者: compose 時間: 2025-3-26 21:08 作者: MURAL 時間: 2025-3-27 02:38
,Der Atomismus der Elektrizit?t,ogic outcomes compared to open resection [1–8]. However, as with any operation for GIST, the adherence to oncologic surgical practices, including prevention of tumor spillage and appropriate resection, must be considered before deciding on a minimally invasive resection [1].作者: 支架 時間: 2025-3-27 05:52 作者: Conduit 時間: 2025-3-27 09:36
,Die künstliche Atomumwandlung,6, 2001), traditional chemotherapy agents failed usually causing stable disease at best without improvement of progression-free or overall survival (OS) (Edmonson et al., Cancer Invest 20(5–6):605–612, 2002; Blay et al., Eur J Cancer 40(9):1327–1331, 2004; Trent et al., Cancer 98(12):2693–2699, 2003作者: CYT 時間: 2025-3-27 14:52
hotographs and illustrationsThis textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book? reviews new data about risk factors for the disease, profiles the new staging 作者: Outwit 時間: 2025-3-27 20:20
https://doi.org/10.1007/978-3-663-11966-1een improved based on recent molecular discoveries. The irruption of tyrosine kinase inhibitors in the field revolutionized the treatment of patients with GIST and became a paradigm of translational research in modern oncology. In this chapter, we would like to discuss the most recent advances in targeted therapy for patients with GIST.作者: Plaque 時間: 2025-3-27 23:41 作者: faddish 時間: 2025-3-28 05:31 作者: Chromatic 時間: 2025-3-28 08:20
Folgen der Lungen- und Pleuraverletzungentreated on a clinical trial with imatinib, a tyrosine kinase receptor inhibitor of KIT. Today, imatinib is approved for use in advanced/metastatic GIST and as adjuvant therapy. Future advances require an understanding of the molecular biology of when imatinib is ineffective, which will open opportunities for new treatments.作者: 蝕刻 時間: 2025-3-28 12:23 作者: glamor 時間: 2025-3-28 18:12
History of GIST,treated on a clinical trial with imatinib, a tyrosine kinase receptor inhibitor of KIT. Today, imatinib is approved for use in advanced/metastatic GIST and as adjuvant therapy. Future advances require an understanding of the molecular biology of when imatinib is ineffective, which will open opportunities for new treatments.作者: Yourself 時間: 2025-3-28 19:09
Operative Management of Gastrointestinal Stromal Tumorshas led to more tailored resections and an expanded role of minimally invasive approaches. This chapter will focus on the open surgical approaches; apply these concepts in the operative management of primary GIST.作者: 改良 時間: 2025-3-29 00:10 作者: 玷污 時間: 2025-3-29 05:53 作者: 高興去去 時間: 2025-3-29 10:08 作者: probate 時間: 2025-3-29 11:49 作者: NEG 時間: 2025-3-29 19:11
Advances on Molecular Characterization and Targeted Therapies on GISTeen improved based on recent molecular discoveries. The irruption of tyrosine kinase inhibitors in the field revolutionized the treatment of patients with GIST and became a paradigm of translational research in modern oncology. In this chapter, we would like to discuss the most recent advances in targeted therapy for patients with GIST.作者: 截斷 時間: 2025-3-29 22:55
Management of Liver Metastases of Gastrointestinal Stromal Tumorsopriate patient selection based on presentation and TKI response guides therapy. Salvage therapy may be possible for patients with GIST patients with hepatic metastases. This chapter reviews the clinical decision-making necessary for effective management of GIST hepatic metastases.作者: 半圓鑿 時間: 2025-3-29 23:56
https://doi.org/10.1007/978-3-642-38186-7n by mutations leading to increased kinase signaling. In contrast, GIST occurring as a part of Carney Triad, Carney-Stratakis Dyad, and hereditary paraganglioma syndromes has unique underlying biology, epidemiology, clinic-pathologic features, and disease course (Table 1).作者: 浮雕 時間: 2025-3-30 04:29
Inherited GIST,n by mutations leading to increased kinase signaling. In contrast, GIST occurring as a part of Carney Triad, Carney-Stratakis Dyad, and hereditary paraganglioma syndromes has unique underlying biology, epidemiology, clinic-pathologic features, and disease course (Table 1).作者: 遵循的規(guī)范 時間: 2025-3-30 08:24
978-3-319-82623-3Springer International Publishing Switzerland 2017作者: 暗語 時間: 2025-3-30 12:47
https://doi.org/10.1007/978-3-319-42632-7Endoscopic evaluation; GIST; Liver resection; Neoadjuvant Rx; multivisceral resections; surgical oncology作者: RENAL 時間: 2025-3-30 20:11 作者: 聯(lián)邦 時間: 2025-3-30 20:44 作者: BADGE 時間: 2025-3-31 02:27
https://doi.org/10.1007/978-3-642-47838-3ecularly heterogeneous group of tumors and the discovery of clinicopathologically distinct subtypes with critical implications for therapeutics, prognosis, and genetic counseling. Histomorphology, immunohistochemistry, and mutational analysis continue to play an exceedingly important role, not only 作者: Permanent 時間: 2025-3-31 07:27 作者: debacle 時間: 2025-3-31 11:17
