標(biāo)題: Titlebook: Gangliosides and Modulation of Neuronal Functions; Hinrich Rahmann Conference proceedings 1987 Springer-Verlag Berlin Heidelberg 1987 Calc [打印本頁(yè)] 作者: Flexible 時(shí)間: 2025-3-21 19:10
書(shū)目名稱(chēng)Gangliosides and Modulation of Neuronal Functions影響因子(影響力)
書(shū)目名稱(chēng)Gangliosides and Modulation of Neuronal Functions影響因子(影響力)學(xué)科排名
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書(shū)目名稱(chēng)Gangliosides and Modulation of Neuronal Functions讀者反饋
書(shū)目名稱(chēng)Gangliosides and Modulation of Neuronal Functions讀者反饋學(xué)科排名
作者: Accrue 時(shí)間: 2025-3-21 22:07 作者: Affection 時(shí)間: 2025-3-22 02:14
Der Weg Ins Zwanzigste Jahrhundert, gangliosides are also present in intracellular structures. These gangliosides likely represent the transient forms moving from the site of biosynthesis to the plasma membrane or from the plasma membrane to the site of degradation.作者: Chronic 時(shí)間: 2025-3-22 06:44
https://doi.org/10.1007/978-3-642-85609-9 can cover distinct surface areas and thus modulate potential functions of membrane components or serve as receptors of external molecules. As sialic acids in most cases are in terminal position of glycoconjugates, these sugars play an important role in membrane functions.作者: 范例 時(shí)間: 2025-3-22 11:25
H. Schloesser,Wilhelm Will (Ingenieur)lly: the sugar headgroup, the acyl chains, and the structure as a unit. These things are beginning to be reasonably well understood. A number of experiments have been performed that aim at unravelling less well understood aspects, and this is probably a good time to stand back and think about them.作者: narcotic 時(shí)間: 2025-3-22 16:13
https://doi.org/10.1007/978-3-662-29374-4hains and are thus the first molecules to be recognized from outside of e.g. a cell, they may influence the interaction of cells with other cells or molecules (see this volume, Schauer & Reuter). Consequently, modification of sialic acids as e.g. 0-acetylation is expected to alter these interaction phenomena and other properties of sialic acids.作者: narcotic 時(shí)間: 2025-3-22 20:02
Peter Michael Osswald,Hans-Joachim Hartungonolayers was determined by phase-sensitive ac voltammetry (1). This current reflects the changes in the interface due to the adsorption, desorption, rearrangement and association (condensing) of gangliosides.作者: 陳腐思想 時(shí)間: 2025-3-22 23:58
Fundamentals of the Biological Properties of Sialic Acids can cover distinct surface areas and thus modulate potential functions of membrane components or serve as receptors of external molecules. As sialic acids in most cases are in terminal position of glycoconjugates, these sugars play an important role in membrane functions.作者: 無(wú)能力之人 時(shí)間: 2025-3-23 02:10
Fundamentals of Physico-Chemistry of Glycolipids in Membraneslly: the sugar headgroup, the acyl chains, and the structure as a unit. These things are beginning to be reasonably well understood. A number of experiments have been performed that aim at unravelling less well understood aspects, and this is probably a good time to stand back and think about them.作者: STALL 時(shí)間: 2025-3-23 07:24
Isolation and Analysis of Gangliosides with O-Acetylated Sialic Acidshains and are thus the first molecules to be recognized from outside of e.g. a cell, they may influence the interaction of cells with other cells or molecules (see this volume, Schauer & Reuter). Consequently, modification of sialic acids as e.g. 0-acetylation is expected to alter these interaction phenomena and other properties of sialic acids.作者: 障礙物 時(shí)間: 2025-3-23 13:02
Stablility of Ganglioside Monolayers at a Liquid/Liquid Interface. A polarographic study of the Ca2+onolayers was determined by phase-sensitive ac voltammetry (1). This current reflects the changes in the interface due to the adsorption, desorption, rearrangement and association (condensing) of gangliosides.作者: JIBE 時(shí)間: 2025-3-23 17:23 作者: Incumbent 時(shí)間: 2025-3-23 20:12
The Use of GM1 Alkaline Hydrolysis Products for the Preparation of Ganglioside Molecular Species andN-acetylation of the N-acetylgalactosamine. The two products are easily separated by conventional column chromatographic procedures. The two different gangliosides derivatives can be submitted to different chemical processes in order to prepare a series of new compounds useful for ganglioside research.作者: JECT 時(shí)間: 2025-3-23 23:36
Fundamentals of Brain Ganglioside Biosynthesis gangliosides are also present in intracellular structures. These gangliosides likely represent the transient forms moving from the site of biosynthesis to the plasma membrane or from the plasma membrane to the site of degradation.作者: essential-fats 時(shí)間: 2025-3-24 04:34 作者: scrutiny 時(shí)間: 2025-3-24 06:49
https://doi.org/10.1007/978-3-642-91961-9al roles in binding specific ligands such as toxins, hormones and growth factors (see 1) and in cell transformation and the development of malignancy (see 2), would seem to provide an example of the interaction of glycolipids with other molecules and, as such, a suitable model for the study of the nature of these interactions.作者: Bombast 時(shí)間: 2025-3-24 11:35
Fundamentals of Ganglioside Structurestration of the gangliosides and the lack of higher neutral glycosphingolipids in the central nervous system of all Chordates, however, must stimulate speculations on their possible role in the specific functions of the brain.作者: 強(qiáng)所 時(shí)間: 2025-3-24 17:59
Computer Predictions of Glycosphingolipid Conformational roles in binding specific ligands such as toxins, hormones and growth factors (see 1) and in cell transformation and the development of malignancy (see 2), would seem to provide an example of the interaction of glycolipids with other molecules and, as such, a suitable model for the study of the nature of these interactions.作者: bourgeois 時(shí)間: 2025-3-24 20:19
History of Ganglioside Researche only sugar-containing lipid in brain. Until 1930, only four kinds of cerebroside were known, namely, phrenosin, kerasin, nervon and hydroxynervon (1). In 1933, Blix found sulfatide or cerebroside sulfuric ester in brain (2). Apart from these relatively simple glycolipids, Landsteiner and Levene, o作者: canvass 時(shí)間: 2025-3-25 03:02 作者: 大量殺死 時(shí)間: 2025-3-25 03:43 作者: 輕推 時(shí)間: 2025-3-25 10:49 作者: 轎車(chē) 時(shí)間: 2025-3-25 14:38
Fundamentals of the Application of MS and NMR in the Study of Ganglioside Structurewith gangliosides ever since their discovery 50 years ago. Whereas most of early work on ganglioside structure was based on more or less degradative chemical methods (1–5), physicochemical methods like mass spectrometry and high resolution nuclear magnetic resonance spectroscopy as a non-destructive作者: 放棄 時(shí)間: 2025-3-25 16:11 作者: 個(gè)阿姨勾引你 時(shí)間: 2025-3-25 22:01
Fundamentals of Physico-Chemical Properties of Gangliosides in Solutionsidue, give the hydrophobic properties to the ganglioside molecule, while the polar carbohydrate portion is responsible for the high hydrophilicity of the molecule. This leeds them to form aggregates in solution, the properties of which depend strongly on even small changes in the hydrophilic or the作者: 愚蠢人 時(shí)間: 2025-3-26 02:49 作者: 斗志 時(shí)間: 2025-3-26 07:26
Peculiarities of Ganglioside-CA2+-Interactionsof the other physiologically relevant cations, for instance magnesium, calcium is generally well known for its more variable complex binding-possibilities, especially with regard to the coordination numbers as well as to the length and the angle of binding or the degree of hydration (1, 2).作者: LITHE 時(shí)間: 2025-3-26 09:23 作者: 敘述 時(shí)間: 2025-3-26 13:46 作者: 一再煩擾 時(shí)間: 2025-3-26 20:44 作者: acheon 時(shí)間: 2025-3-26 21:22 作者: 廣告 時(shí)間: 2025-3-27 03:09
Influence of Ca2+ and Temperature Changes on the Surface Requirement of Gangliosides and Phospholipial mixtures of peptides and gangliosides and of natural ganglioside mixtures from bovine and ice- fish brain were investigated by means of a Wilhelmy balance in a rectangular teflon trough. The surface pressure/area isotherms were compared at 11°, 20° and 37° C and different Ca.-concentrations in th作者: fringe 時(shí)間: 2025-3-27 08:14 作者: Synapse 時(shí)間: 2025-3-27 13:07
Fundamentals of Brain Ganglioside Biosynthesise asymmetrically located in the outer membrane leaflet with their oligosaccharide moiety protruding on the membrane surface (1). Very small amounts of gangliosides are also present in intracellular structures. These gangliosides likely represent the transient forms moving from the site of biosynthes作者: Esophagus 時(shí)間: 2025-3-27 15:37
https://doi.org/10.1007/978-3-662-29377-5 the orcinol reaction (3–6). At the end of their work, they made the following statement: “The composition of our preparation suggests the possibility that they contain certain specific groups similar to those of the bacterial haptenes studied by Avery and Heidelberger.” Thus they assumed the active作者: 反感 時(shí)間: 2025-3-27 19:37 作者: hegemony 時(shí)間: 2025-3-28 01:25
https://doi.org/10.1007/978-3-642-91938-1side analysis is intimately connected with the introduction of fast atom bombardment mass spectrometry (FAB-MS) (10,11). With this ‘soft ionization’ technique that allows ionization of polar compounds from a solution in a high boiling liquid in combination with high field magnets and highly sensitiv作者: 搜尋 時(shí)間: 2025-3-28 02:52
https://doi.org/10.1007/978-3-662-36686-8entially, a DEAE-resin column, mild base treatment, desalting, and a silica gel column (5,6). This procedure has now become popular. Byrne et al. (7) reported the further improvement of this method by including an additional step using a Sephadex LH-20 column eluted with 0.05N HCl.作者: 背心 時(shí)間: 2025-3-28 06:38 作者: 小丑 時(shí)間: 2025-3-28 11:50
Fundamentals of Structural Analysis of Glycosphingolipids by Proton Nuclear Magnetic Resonance Specty, on the other hand, is well-suited for providing the primary and secondary structure of glycosphingolipids because this method is rapid, quantitative, sensitive and nondestructive. However, previous utilization of proton NMR has yielded only incomplete data concerning the primary structure of thes作者: 集聚成團(tuán) 時(shí)間: 2025-3-28 17:05 作者: 欲望 時(shí)間: 2025-3-28 21:41
Up-To-Date Chromatography of Gangliosidesentially, a DEAE-resin column, mild base treatment, desalting, and a silica gel column (5,6). This procedure has now become popular. Byrne et al. (7) reported the further improvement of this method by including an additional step using a Sephadex LH-20 column eluted with 0.05N HCl.作者: 在前面 時(shí)間: 2025-3-29 00:00 作者: fledged 時(shí)間: 2025-3-29 04:43 作者: 賄賂 時(shí)間: 2025-3-29 09:53 作者: Ferritin 時(shí)間: 2025-3-29 12:37
https://doi.org/10.1007/978-3-642-85609-9er cells and molecules and thus regulate the social behaviour and other functions of mobile and resident cells of organisms. As components on the surface of mammalian cells they occur linked to protein or lipid which are in turn anchored in the lipid bilayer of the cell membrane. There carbohydrates作者: 金絲雀 時(shí)間: 2025-3-29 18:20
https://doi.org/10.1007/978-3-662-05540-3different chemical constitution of their ceramide-linked carbohydrate moieties. Amongst these, it is by definition the sialic acid*-containing mono- and oligosaccharides that in particular characterise the group of the gangliosides (for review, see (1)). Whether or not the occurrence of sialic acid 作者: CEDE 時(shí)間: 2025-3-29 21:26 作者: gait-cycle 時(shí)間: 2025-3-30 00:24 作者: 能量守恒 時(shí)間: 2025-3-30 04:14 作者: Optometrist 時(shí)間: 2025-3-30 11:14 作者: enumaerate 時(shí)間: 2025-3-30 14:01
H. Schloesser,Wilhelm Will (Ingenieur)s. However certain points remain very unclear. One would certainly like to know how glycolipids ‘fit’ into membranes: what forces hold them in place, what effect they have on the membrane, and how they are oriented. One would also like to know how the various portions of the molecule behave dynamica作者: SEVER 時(shí)間: 2025-3-30 18:26 作者: 正式通知 時(shí)間: 2025-3-31 00:41
https://doi.org/10.1007/978-3-662-29374-4cetylneuraminic acid (Neu5Ac) > N-glycolylneuraminic acid (Neu5Gc) > N-acetyl-9-0-acetylneuraminic acid (Neu5,9Ac.) > N-glycolyl-9-0-acetylneuraminic acid (Neu9Ac5Gc) > N-acetyl-4-0-acetylneuraminic acid (Neu4,5Ac.). As sialic acids are in most cases linked to the terminal position of carbohydrate c作者: 假設(shè) 時(shí)間: 2025-3-31 04:04
https://doi.org/10.1007/978-3-662-36686-8nce gangliosides are involved in strong interactions with other components in membranes of both ionic and hydrophobic nature as well as due to hydrogen bonding, mixed organic solvents containing water are required for their quantitative extraction (1,2). Taking advantage of the water- soluble nature作者: 新奇 時(shí)間: 2025-3-31 05:05
https://doi.org/10.1007/978-3-642-92070-7yl-GM1, deacetylated at the level of the sialic acid, and deacetyl-deacyl-GMl, deacetylated at the level of the lipid moiety, without occurence of de-N-acetylation of the N-acetylgalactosamine. The two products are easily separated by conventional column chromatographic procedures. The two different作者: LAP 時(shí)間: 2025-3-31 09:19 作者: exhilaration 時(shí)間: 2025-3-31 16:54 作者: Hyperalgesia 時(shí)間: 2025-3-31 21:09 作者: Bother 時(shí)間: 2025-3-31 22:08
Der Weg Ins Zwanzigste Jahrhundert,e asymmetrically located in the outer membrane leaflet with their oligosaccharide moiety protruding on the membrane surface (1). Very small amounts of gangliosides are also present in intracellular structures. These gangliosides likely represent the transient forms moving from the site of biosynthes作者: noxious 時(shí)間: 2025-4-1 04:53 作者: floaters 時(shí)間: 2025-4-1 08:21
