標(biāo)題: Titlebook: GTPase Protocols; The Ras Superfamily Ed Manser,Thomas Leung Book 2002 Humana Press 2002 [打印本頁] 作者: Combat 時(shí)間: 2025-3-21 17:44
書目名稱GTPase Protocols影響因子(影響力)
書目名稱GTPase Protocols影響因子(影響力)學(xué)科排名
書目名稱GTPase Protocols網(wǎng)絡(luò)公開度
書目名稱GTPase Protocols網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱GTPase Protocols被引頻次
書目名稱GTPase Protocols被引頻次學(xué)科排名
書目名稱GTPase Protocols年度引用
書目名稱GTPase Protocols年度引用學(xué)科排名
書目名稱GTPase Protocols讀者反饋
書目名稱GTPase Protocols讀者反饋學(xué)科排名
作者: 按等級(jí) 時(shí)間: 2025-3-21 22:38
Yoshinori Hara,Senko Ikenobo,Spring H. Hane are the organization and dynamics of the actin cytoskeleton, intercellular and cell-substrate adhesion, vesicle trafficking, and lipid metabolism (.). Recently, Rac has been shown to stimulate the transcription of collagenase-1, a metalloproteinase involved in the remodeling of extracellular matrix (.).作者: Indecisive 時(shí)間: 2025-3-22 04:07 作者: keloid 時(shí)間: 2025-3-22 07:20 作者: 驕傲 時(shí)間: 2025-3-22 11:59 作者: gruelling 時(shí)間: 2025-3-22 15:28
Effects of Rho Family GTPases on Cell-Cell Adhesion, which in turn is linked to the actin cytoskeleton via α-catenin. This linkage between cadherins and the actin cytoskeleton is required for the development of a strong adhesive state (.). However, the mechanism underlying the dynamic rearrangement in cell-cell adhesion remains unclear.作者: gruelling 時(shí)間: 2025-3-22 19:48
French Unification Categorial Grammars,itogen activated protein kinase (MAPK) cascade. Constitutively activated, mutant forms of Ras such as RasV12 are found frequently in human tumors, and it is widely assumed that this oncogene acts via transcriptional activation of growth and proliferation pathways.作者: Interregnum 時(shí)間: 2025-3-22 21:57 作者: 糾纏,纏繞 時(shí)間: 2025-3-23 03:14 作者: JOG 時(shí)間: 2025-3-23 06:12
Using cDNA-Representational Difference Analysis (cDNA-RDA) in Combination with Microarrays to Identiitogen activated protein kinase (MAPK) cascade. Constitutively activated, mutant forms of Ras such as RasV12 are found frequently in human tumors, and it is widely assumed that this oncogene acts via transcriptional activation of growth and proliferation pathways.作者: DEVIL 時(shí)間: 2025-3-23 12:57 作者: AXIOM 時(shí)間: 2025-3-23 17:00 作者: 鈍劍 時(shí)間: 2025-3-23 18:07
1064-3745 spect of cell biology. In the 1980s the pro- oncogene Ras itself was the focus of interest, though in the 1990s this shifted to the increasing variety of Ras-related proteins. In this new decade much yet needs to be done to establish the role for all the small GTPases now uncovered by the human geno作者: Discrete 時(shí)間: 2025-3-24 00:53
Pierre J. Magistretti,Fran?ois Ansermetcaused by a combination of the following genetic events: overexpression of a protooncogene or constitutive activation of its gene product (mitogenic signal transducer), and deletion of a tumor-suppressor gene (also called anti-oncogene or anti-mitogenic gene) or dysfunction of its gene product (anti-mitogenic signal transducer).作者: 自然環(huán)境 時(shí)間: 2025-3-24 03:27 作者: 軍械庫 時(shí)間: 2025-3-24 07:53
https://doi.org/10.1007/978-3-319-57978-8nalysis of their kinetics and thermodynamic properties in order to quantify these processes in vivo. It therefore becomes increasingly important to examine these interactions by appropriate real-time methods.作者: Pedagogy 時(shí)間: 2025-3-24 14:06
Fluorescence Methods in the Study of Small GTP-Binding Proteinsnalysis of their kinetics and thermodynamic properties in order to quantify these processes in vivo. It therefore becomes increasingly important to examine these interactions by appropriate real-time methods.作者: fidelity 時(shí)間: 2025-3-24 16:13 作者: Spinous-Process 時(shí)間: 2025-3-24 21:58 作者: aesthetician 時(shí)間: 2025-3-25 00:48
The GTPase Cycle How Dominant Inhibitory Mutants Block the Biological Functions of Small GTPasesominant inhibitory” proteins. These proteins have emerged as popular tools to accomplish GTPase inhibition in mammalian cells; mutated proteins can interfere with the function of their normal cellular counterparts or with the proteins that interact with them. This approach has been used extensively 作者: 過份好問 時(shí)間: 2025-3-25 06:44 作者: Abrade 時(shí)間: 2025-3-25 08:49 作者: 很像弓] 時(shí)間: 2025-3-25 14:03 作者: Minuet 時(shí)間: 2025-3-25 15:51 作者: 他去就結(jié)束 時(shí)間: 2025-3-25 22:08 作者: convert 時(shí)間: 2025-3-26 00:28
ARF-Directed Guanine-Nucleotide-Exchange (GEP) Proteinstivating protein (GAP), which accelerates GTP hydrolysis. Activation of the inactive GDP-bound ARF requires the action of a guanine nucleotide-exchange protein or GEP, which accelerates the release of bound nucleotide via stabilization of the guanine nucleotide-free protein (.).作者: 歌曲 時(shí)間: 2025-3-26 06:31
Arf6 and its Role in Cytoskeletal ModulationR) and Golgi complex and in the maintenance of the organization of the Golgi complex (.). Arf1 serves this dual function through the modification of Golgi-membrane lipid composition and the assembly of cytosolic coat-protein complexes onto Golgi membranes.作者: Flat-Feet 時(shí)間: 2025-3-26 08:53 作者: 糾纏 時(shí)間: 2025-3-26 13:24 作者: farewell 時(shí)間: 2025-3-26 18:46 作者: chronology 時(shí)間: 2025-3-27 00:40 作者: 漸強(qiáng) 時(shí)間: 2025-3-27 04:31
*Non-Euclidean (Hyperbolic) Geometry,ses are further regulated by guanine-nucleotide dissociation inhibitors (GDIs), which can inhibit both the exchange of GTP and the hydrolysis of bound GTP. Rho GDIs, as well as members of the ERM family (ezrin, radixin, and moesin), also appear to play a crucial role in the translocation of Rho-like作者: 爆炸 時(shí)間: 2025-3-27 05:29 作者: 我要沮喪 時(shí)間: 2025-3-27 10:46
Robyn Klingler-Vidra,Yu Ching Kuois coupled to the delivery of a Rab GTPase to a specific membrane compartment (.,.); the Rab GTPase is subsequently converted to the GTP-bound form by the action of a GEP. The GTP-bound form then interacts with a downstream effector(s). Thereafter, the GTP-bound form is converted to the GDP-bound fo作者: insipid 時(shí)間: 2025-3-27 14:02
Eric Hershberg,William M. LeoGrandend to function as regulators of membrane traffic and the actin cytoskeleton (.–.). In biochemical studies, Arfs have also been found to activate phospholipase D (PLD) and phosphatidylinositol 4-phosphate 5-kinase, and to bind to several putative effectors such as arfaptin, arfophilin, and the GGAs (作者: ironic 時(shí)間: 2025-3-27 19:16 作者: Constrain 時(shí)間: 2025-3-28 01:31
https://doi.org/10.1007/978-3-030-20675-8R) and Golgi complex and in the maintenance of the organization of the Golgi complex (.). Arf1 serves this dual function through the modification of Golgi-membrane lipid composition and the assembly of cytosolic coat-protein complexes onto Golgi membranes.作者: 機(jī)警 時(shí)間: 2025-3-28 02:20 作者: GRAZE 時(shí)間: 2025-3-28 08:59 作者: 煞費(fèi)苦心 時(shí)間: 2025-3-28 13:26
Preparation of GTPases for Structural and Biophysical Analysisentiation and proliferation, membrane trafficking, and nuclear import and export. Based on sequence homology, this superfamily can be divided into the Ras, Rho, Ran, Arf, Rab, and Rad subfamilies, which all have distinct biological activities. All members of this superfamily act as molecular switche作者: Visual-Field 時(shí)間: 2025-3-28 18:39
Using cDNA-Representational Difference Analysis (cDNA-RDA) in Combination with Microarrays to Identi diphosphate (GDP)-bound state. They integrate signals from the cell surface to the nucleus, regulating important cellular activities. For example, Ras itself is activated when extracellular growth factors such as platelet derived growth factor (PDGF) or epidermal growth facor (EGF) bind to their re作者: CRATE 時(shí)間: 2025-3-28 20:04 作者: 勾引 時(shí)間: 2025-3-29 02:45
Ras and Rac as Activators of Reactive Oxygen Species (ROS)enced a recent surge in interest. Known to cause DNA damage, and implicated in disease processes as wide-ranging as atherosclerosis and kidney disease, ROS have appeared in unlikely capacities within the Ras signaling pathway. Eschewing their evil ways, ROS have been shown to be essential for mitoge作者: 復(fù)習(xí) 時(shí)間: 2025-3-29 03:42
Interfering with Ras Signaling Using Membrane-Permeable Peptides or Drugsne (proto-oncogene) encoding a Tyr kinase called c-Src in early 1980s, it was firmly established that the malignant transformation of normal cells is caused by a combination of the following genetic events: overexpression of a protooncogene or constitutive activation of its gene product (mitogenic s作者: 逗留 時(shí)間: 2025-3-29 07:31
A Ras-Based Module to Generate 32P-Labeled Fusion Proteins for Blot Overlaysid screening. Of these, the blot overlay protocol of sodium dodecyl sulfate (SDS)-acrylamide-gel-separated proteins provides perhaps the most direct assessment of target binding, since one can simultaneously screen multiple cell types or tissue extracts, and infer the size-and in some cases the rela作者: Fretful 時(shí)間: 2025-3-29 11:33 作者: Ingest 時(shí)間: 2025-3-29 17:07 作者: formula 時(shí)間: 2025-3-29 21:58 作者: 輕快來事 時(shí)間: 2025-3-30 00:52
Cell Motility and Invasion Assaysmune function. Deregulated motile behavior is believed to contribute to pathological processes such as metastasis, tumor angiogenesis, and atherosclerosis (.–.). Rho family members control a multitude of functions that have been implicated in the regulation of cell migration. Most notable among thes作者: 粗魯性質(zhì) 時(shí)間: 2025-3-30 04:22
Isolation of Regulatory Proteins for the Rab3 Subfamily GTPasesosis, and transcytosis (.–.). All the Rab GTPases have unique C-terminal structures, which undergo posttranslational modifications with geranylgeranyl moieties in most cases. Rab GTPases cycle between the guanosine diphosphate (GDP)-bound inactive and guanosine triphosphate (GTP)-bound active forms 作者: HILAR 時(shí)間: 2025-3-30 10:25 作者: Accomplish 時(shí)間: 2025-3-30 15:24 作者: 連接 時(shí)間: 2025-3-30 19:45 作者: maudtin 時(shí)間: 2025-3-30 21:29
Arf6 and its Role in Cytoskeletal Modulationmino-acid sequence. Class I Arfs include mammalian Arfs 1-3, Class II includes Arfs 4, and 5, and Class III Arfs have only one member-Arf6 (.). All Arf proteins have been shown to share a number of biochemical properties in vitro including: serving as cofactors in the ADP-ribosylation of Gs-alpha su作者: antenna 時(shí)間: 2025-3-31 02:13 作者: 誘拐 時(shí)間: 2025-3-31 05:25 作者: 小教堂 時(shí)間: 2025-3-31 10:59
Random Variables and Random Vectors,entiation and proliferation, membrane trafficking, and nuclear import and export. Based on sequence homology, this superfamily can be divided into the Ras, Rho, Ran, Arf, Rab, and Rad subfamilies, which all have distinct biological activities. All members of this superfamily act as molecular switche作者: 不可接觸 時(shí)間: 2025-3-31 17:15 作者: 光明正大 時(shí)間: 2025-3-31 20:39 作者: Obstacle 時(shí)間: 2025-4-1 01:11
Edin Terzic,Jenny Terzic,Muhammad Alamgirenced a recent surge in interest. Known to cause DNA damage, and implicated in disease processes as wide-ranging as atherosclerosis and kidney disease, ROS have appeared in unlikely capacities within the Ras signaling pathway. Eschewing their evil ways, ROS have been shown to be essential for mitoge作者: 打包 時(shí)間: 2025-4-1 02:21
Pierre J. Magistretti,Fran?ois Ansermetne (proto-oncogene) encoding a Tyr kinase called c-Src in early 1980s, it was firmly established that the malignant transformation of normal cells is caused by a combination of the following genetic events: overexpression of a protooncogene or constitutive activation of its gene product (mitogenic s作者: 揭穿真相 時(shí)間: 2025-4-1 07:19 作者: nocturnal 時(shí)間: 2025-4-1 12:32
*Non-Euclidean (Hyperbolic) Geometry, of cytoskeletal structures, adhesion, motility, transcriptional activation, and cell-cycle progression (.–.). The Rho-like GTPases comprise a subfamily of the Ras superfamily of small guanosine triphosphate (GTP)-binding proteins. Like all members of the Ras superfamily, the Rho-GTPases function as
