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標(biāo)題: Titlebook: GABA: Receptors, Transporters and Metabolism; Chikako Tanaka (Professor Emeritus, Director),Norm Book 1996 Birkh?user Verlag 1996 Calcium. [打印本頁]

作者: 大口水罐    時間: 2025-3-21 19:25
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作者: encyclopedia    時間: 2025-3-21 21:10
Ahmet Toprak Dr. phil., Dipl.-P?dagogephase in Triton X-114 partitioning assay, shift in electrophoretic mobility in the presence of ionic detergent and elution by low ionic strength buffer in hydrophobic interaction chromatography. Based on these observations, it is hypothesized that M-GADI and M-GADII may be involved in the pathogenes
作者: osteoclasts    時間: 2025-3-22 01:17
Ziele und Verlauf der Untersuchung,ve glycosylation sites. An orphan subfamily (NTT4), somewhat remote from the other subfamilies of Na./C1.-dependent transporters, was identified from mammalian sources (11,12). This subfamily of putative neurotransmitter transporters has no known function but is highly expressed in different parts o
作者: endoscopy    時間: 2025-3-22 05:06
Existentialismus, Absurdismus, Indifferenz, Ca. ([Ca.].) as well as transmitter release was dependent on coupling to G-proteins although this G-protein coupling appears to be rather complex. Finally, an interaction between GABA. and GABA. receptors seems to exist with regard to regard to regulation of transmitter release.
作者: Altitude    時間: 2025-3-22 12:38

作者: 臆斷    時間: 2025-3-22 14:28

作者: 臆斷    時間: 2025-3-22 18:25

作者: 邪惡的你    時間: 2025-3-22 21:41

作者: 影響帶來    時間: 2025-3-23 03:57

作者: Matrimony    時間: 2025-3-23 09:11

作者: Inordinate    時間: 2025-3-23 16:08

作者: 阻撓    時間: 2025-3-23 20:29

作者: 劇毒    時間: 2025-3-23 22:41

作者: 乞丐    時間: 2025-3-24 02:54
https://doi.org/10.1007/978-3-476-03468-7in the termination of synaptic transmission. The GABA transporter GAT-1 is the first neurotransmitter transporter to be purified, reconstituted and cloned. It belongs to a large superfamily of neurotransmitter transporters. Its properties and its relation to the other family members will be discusse
作者: deficiency    時間: 2025-3-24 10:17

作者: corporate    時間: 2025-3-24 13:52
Ziele und Verlauf der Untersuchung,otransport with sodium utilizing the energy stored in transmembrane electrochemical gradients generated by primary ion pumps. Studies on neurotransmitter uptake indicated the existence of multiple uptake systems, each relatively selective for a specific neurotransmitter. A family of Na./Cl. neurotra
作者: 親密    時間: 2025-3-24 17:51

作者: 門窗的側(cè)柱    時間: 2025-3-24 19:31

作者: 凹處    時間: 2025-3-25 01:08
Existentialismus, Absurdismus, Indifferenz,s well as GABA. receptors. These receptors are coupled to regulation of transmitter release as well as intracellular Ca. homeostasis. Transmitter release elicited by moderate depolarization can be inhibited either by GABA. or GABA. receptor agonists whereas transmitter release evoked by a more prono
作者: 最小    時間: 2025-3-25 03:56

作者: 巨頭    時間: 2025-3-25 10:30
https://doi.org/10.1007/978-3-476-03661-2oocytes per 1 min. Stimulation with Ca. ionophore (A23187) produced increase in the release of [.H]GABA from the mRNA-injected oocytes. 12-.-tetradecanoylphorbol 13-acetate (TPA) (10 nM – 300 nM), but not 4α-phorbol-12,13-didecanoate (300 nM) potentiated the A23187-evoked release of [.H]GABA from th
作者: colloquial    時間: 2025-3-25 13:24

作者: 不溶解    時間: 2025-3-25 18:54

作者: 壓倒性勝利    時間: 2025-3-25 23:35

作者: CLAIM    時間: 2025-3-26 01:52
Der grosse P?bel- und Sklavenaufstandnation of molecular, and physiological approaches. Direct phosphorylation by either PKA, or PKC inhibited receptor function, whilst tyrosine phosphorylation enhanced receptor function. Together these results suggest that GABA. receptors are under the control of multiple cell signalling pathways that
作者: debble    時間: 2025-3-26 08:23
Hanspeter Krellmann,Jürgen Schl?derleus (MVN) neurons and GABA-induced currents in primarily cultured cortical neurons were examined. 20-HE (10–50mg/kg) inhibited tonic convulsions in SER without affecting the absence-like seizures. The inhibition was antagonized by pretreatment with bicuculline. The rotation-induced firing of the MV
作者: Estimable    時間: 2025-3-26 09:02

作者: 機制    時間: 2025-3-26 16:03
Schlu?betrachtungen: Die Schuld der Physikiabetes mellitus (IDDM) or other diseases and 461 normal subjects. Anti-GAD antibody was detected in the CSF of a patient with epilepsy and cerebellar atrophy who was administered phenytoin for more than 20 years. Anti-GAD antibody was detected in the serum of 36.6% patients with IDDM.
作者: 情愛    時間: 2025-3-26 17:17
https://doi.org/10.1007/978-3-476-03468-7in the termination of synaptic transmission. The GABA transporter GAT-1 is the first neurotransmitter transporter to be purified, reconstituted and cloned. It belongs to a large superfamily of neurotransmitter transporters. Its properties and its relation to the other family members will be discussed.
作者: modest    時間: 2025-3-27 00:28

作者: 跟隨    時間: 2025-3-27 01:40

作者: 難取悅    時間: 2025-3-27 08:26

作者: tangle    時間: 2025-3-27 10:41
978-3-0348-9858-4Birkh?user Verlag 1996
作者: 抓住他投降    時間: 2025-3-27 15:39
https://doi.org/10.1007/978-3-0348-8990-2Calcium; GABA; Glutamat; Nervous System; biology; central nervous system; development; immunity; metabolism;
作者: depreciate    時間: 2025-3-27 20:00
Establishment of GABA as an Inhibitory Neurotransmitter at Crustacean Neuromuscular Junction and in 63 that inhibitory axons of lobsters contain about 200 times higher concentration of GABA than excitatory axons, which strongly suggested that GABA is an inhibitory transmitter. When I joined the Kuffler’s group in 1964, one crucial piece of evidence was missing, namely the demonstration of the rele
作者: 放縱    時間: 2025-3-28 00:33

作者: Nucleate    時間: 2025-3-28 03:19
Membrane Associated L-Glutamate Decarboxylase and Insulin-Dependent Diabetes Mellitus (IDDM)ified from porcine brain. M-GADI and M-GADII appear to be integral membrane proteins whereas M-GADIII is a peripheral protein attached to membranes in a Ca. dependent manner. In addition, M-GADI and M-GADII were found to be the major autoantigens in insulin-dependent diabetes mellitus (IDDM), also k
作者: Salivary-Gland    時間: 2025-3-28 08:11

作者: Ebct207    時間: 2025-3-28 14:07
Anti-GAD Antibody in Various Neurological Diseasesiabetes mellitus (IDDM) or other diseases and 461 normal subjects. Anti-GAD antibody was detected in the CSF of a patient with epilepsy and cerebellar atrophy who was administered phenytoin for more than 20 years. Anti-GAD antibody was detected in the serum of 36.6% patients with IDDM.
作者: Morbid    時間: 2025-3-28 14:51
GABA Transporters: Structure, Function and Mechanismin the termination of synaptic transmission. The GABA transporter GAT-1 is the first neurotransmitter transporter to be purified, reconstituted and cloned. It belongs to a large superfamily of neurotransmitter transporters. Its properties and its relation to the other family members will be discusse
作者: Arctic    時間: 2025-3-28 22:38
Heterogeneity of Brain GABA Transporterserapeutic targets, we have applied a combined approach including cDNA cloning, pharmacological characterization, mRNA localization, and synthesis of novel GABA uptake inhibitors. Four high-affinity GABA transporters are present in brain and each has a unique pattern of mRNA distribution, with multip
作者: octogenarian    時間: 2025-3-28 23:50
Developmental Expression of the GABA Transporter GAT4otransport with sodium utilizing the energy stored in transmembrane electrochemical gradients generated by primary ion pumps. Studies on neurotransmitter uptake indicated the existence of multiple uptake systems, each relatively selective for a specific neurotransmitter. A family of Na./Cl. neurotra
作者: 本能    時間: 2025-3-29 06:24

作者: 一罵死割除    時間: 2025-3-29 08:17
GABAB Receptor Control of Transmitter Release in the Spinal Cordected dorsal horn slice, evoked by electrical stimulation of primary dorsal afferents. CGP36742, CGP55845A and CGP52432 reversed the inhibitory effect that (?)-baclofen had on the stimulated outflow of GABA, glutamate and substance P-like immunoreactivity. CGP56999A was without effect on the baclofe
作者: 整潔    時間: 2025-3-29 13:04
Role of GABAA and GABAB Receptors in Ca++ Homeostasis and Transmitter Release in Cerebellar Granule s well as GABA. receptors. These receptors are coupled to regulation of transmitter release as well as intracellular Ca. homeostasis. Transmitter release elicited by moderate depolarization can be inhibited either by GABA. or GABA. receptor agonists whereas transmitter release evoked by a more prono
作者: 殘暴    時間: 2025-3-29 17:16
Interactions between Endogenous L-DOPA and GABA, Systems for Cardiovascular Control in the Rat Nucle by bicuculline 10 ng. By microdialysis, basal L-DOPA release was reduced by muscimol 10 to 30 μM perfused via a probe by 50–60% whereas increased by bicuculline 30 μM by 40%. Pressor responses to 300 ng GABA were reduced by 50% by a competitive L-DOPA antagonist, L-DOPA methyl ester 1 μg. Meanwhile
作者: arboretum    時間: 2025-3-29 22:10

作者: BOAST    時間: 2025-3-30 01:00
The Molecular Biology of GABAA Receptors and Its Applications, α2 and α3 subunits discovered were much more similar to each other than to a β subunit and hence these were designated as in two families, α and β (2). The range has been extended in studies, mainly by Peter Seeburg and co-workers and in some cases by others (reviewed in refs. 3,4) to a present to
作者: BOON    時間: 2025-3-30 05:41
Modelling Functional Domains of the GABAA Receptor Chloride Channeluctural motif that may be coupled to channel gating. We recently identified amino acids (F65 and H102 in bovine . 1 subunit) as sites of photoaffinity labelling with GABA and benzodiazepine (BZ) ligands respectively. The two domains, TIDVFFR(61–67) for GABA and TPDTFFH(96–102) for BZ show sequence h
作者: 圓桶    時間: 2025-3-30 10:22

作者: ungainly    時間: 2025-3-30 15:59

作者: 過渡時期    時間: 2025-3-30 19:44

作者: 死亡率    時間: 2025-3-31 00:45

作者: 調(diào)情    時間: 2025-3-31 01:21

作者: GRIN    時間: 2025-3-31 05:18

作者: bizarre    時間: 2025-3-31 11:43

作者: 碌碌之人    時間: 2025-3-31 14:03

作者: flaunt    時間: 2025-3-31 19:53
Interactions between Endogenous L-DOPA and GABA, Systems for Cardiovascular Control in the Rat Nucle, L-DOPA 1–100 nM perfused released GABA by 35–60%. This release was not mimicked by D-DOPA and dopamine 10 nM, not affected by inhibition of central DOPA decarboxylase, and was markedly reduced by Ca. deprivation or tetrodotoxin 1μm.
作者: 的是兄弟    時間: 2025-3-31 23:05

作者: 積云    時間: 2025-4-1 04:33

作者: 隨意    時間: 2025-4-1 06:05

作者: 聯(lián)想    時間: 2025-4-1 10:53

作者: keloid    時間: 2025-4-1 14:20
Der grosse P?bel- und Sklavenaufstandlation enhanced receptor function. Together these results suggest that GABA. receptors are under the control of multiple cell signalling pathways that can selectively up and down regulate function. Such “cross talk” may have profound effects on inhibitory synaptic transmission mediated by GABA. receptors.
作者: 機制    時間: 2025-4-1 19:09
Establishment of GABA as an Inhibitory Neurotransmitter at Crustacean Neuromuscular Junction and in an inhibitory transmitter. When I joined the Kuffler’s group in 1964, one crucial piece of evidence was missing, namely the demonstration of the release of GABA from an inhibitory axon by stimulation. This was successfully achieved in 1966 by Otsuka, Iversen, Hall and Kravitz.
作者: AGONY    時間: 2025-4-2 02:26
Stiff-Man Syndrome and Glutamic Acid Decarboxylase: An Updated View acid decarboxylase (GAD), the enzyme responsible for the synthesis of GABA. In this chapter, we summarize some of the relevant features of SMS and GAD, with an emphasis on the contribution of our group to this field.
作者: 不開心    時間: 2025-4-2 06:50
GABA,-Receptor Subtypes: Pharmacological Significance and Mutational Analysis ,sessed by mutational analysis .. Benzodiazepine-insensitive mice were generated by targeted disruption of the γ2-subunit gene. For drug development, GABA.-receptor heterogeneity offers new opportunities to advance the therapy of anxiety, insomnia, and epilepsy with ligands acting at selected modulatory sites.




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