標(biāo)題: Titlebook: G Proteins, Receptors, and Disease; Allen M. Spiegel (Chief, Metabolic Diseases Branch Book 1998 Springer Science+Business Media New York [打印本頁(yè)] 作者: Boldfaced 時(shí)間: 2025-3-21 18:00
書(shū)目名稱(chēng)G Proteins, Receptors, and Disease影響因子(影響力)
書(shū)目名稱(chēng)G Proteins, Receptors, and Disease影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)G Proteins, Receptors, and Disease網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)G Proteins, Receptors, and Disease網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)G Proteins, Receptors, and Disease被引頻次
書(shū)目名稱(chēng)G Proteins, Receptors, and Disease被引頻次學(xué)科排名
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書(shū)目名稱(chēng)G Proteins, Receptors, and Disease讀者反饋
書(shū)目名稱(chēng)G Proteins, Receptors, and Disease讀者反饋學(xué)科排名
作者: Haphazard 時(shí)間: 2025-3-22 00:07
Albright Hereditary Osteodystrophy, Pseudohypoparathyroidism, and Gs Deficiency, characterized by hypocalcemia, hyperphosphatemia, and elevation of serum PTH in the setting of normal renal function, is the major clinical feature. In the original report by Fuller Albright, PHP patients showed reduced calcemic and phosphaturic responses to injected bovine parathyroid extract comp作者: opportune 時(shí)間: 2025-3-22 04:18
,Gαs-Activating Mutations,ot only in all vertebrates, but also in invertebrates, such as . and .. G. couples receptors for numerous peptide hormones and monoamines to stimulation of adenylyl cyclase. Although it is now clear that G-protein βγ-subunits can independently modulate adenylyl cyclase (positively or negatively depe作者: arthrodesis 時(shí)間: 2025-3-22 06:28 作者: 形容詞詞尾 時(shí)間: 2025-3-22 12:14 作者: 厚臉皮 時(shí)間: 2025-3-22 13:08
,Gα12- and Gα13-Subunits of Heterotrimeric G-Proteins A Novel Family of Oncogenes,receptors in normal and aberrant cell growth. As such, a number of oncogenes have been found to code for altered forms of these receptors ., their ligands (.), or for molecules thought to participate in their growth-promoting pathways .. Another family of structurally related cell-surface receptors 作者: 厚臉皮 時(shí)間: 2025-3-22 18:53
Hypo- and Hyperthyroidism Caused by Mutations of the TSH Receptor,imarily through a positive control exerted by the pituitary hormone thyroid stimulating hormone (TSH) and a negative control exerted by iodine. In most physiological circumstances the maintenance of eumetabolism requires steady concentrations of circulating thyroid hormones. This is achieved by a cl作者: parasite 時(shí)間: 2025-3-22 22:18 作者: Malcontent 時(shí)間: 2025-3-23 02:56
Inactivating and Activating Mutations of the FSH Receptor Gene,that participate in the regulation of reproductive functions, and those of the gonadotropin receptors (R) have received considerable attention. Since the discovery of the first luteinizing hormone receptor (LHR) mutations in 1993 ., more than 15 mutations have been so far reported in this gene (. Ch作者: 誹謗 時(shí)間: 2025-3-23 09:12
Nephrogenic Diabetes Insipidus and Vasopressin Receptor Mutations,g tubules contain selective cells known as principal cells, responsive to the neurohypophyseal antidiuretic hormone arginine-vasopressin (AVP). The major action of AVP is to facilitate urinary concentration by allowing water to be transported passively down an osmotic gradient between the tubular fl作者: 行乞 時(shí)間: 2025-3-23 10:59
Disorders with Increased or Decreased Responsiveness to Extracellular Ca2+ Owing to Mutations in th and enzymatic cofactor that coordinates and controls cellular processes as diverse as muscular contraction, secretion, and glycogen metabolism as well as cellular proliferation, differentiation, and motility .. The basal level of Ca. ., generally~100 n., is much lower than the extracellular ionized作者: biopsy 時(shí)間: 2025-3-23 16:49 作者: Stagger 時(shí)間: 2025-3-23 19:21
Mutation of the Growth Hormone-Releasing Hormone Receptor in the little Mouse,ph cells to stimulate the synthesis and secretion of GH (.). The actions of GHRH are opposed by those of somatostatin, a peptide hormone of hypothalamic origin that acts to suppress pituitary growth hormone secretion; together, GHRH and somatostatin are thought to be the predominant mediators of the作者: 禍害隱伏 時(shí)間: 2025-3-24 00:31
Functional Variants of the MSH Receptor (MC1-R), Agouti, and Their Effects on Mammalian Pigmentatiohat plays an important role in the regulation of mammalian pigmentation. No diseases and in fact no pigmentation phenotypes in humans have been definitively linked to this receptor. Nevertheless, the study of the MC 1 -R has introduced at least two novel paradigms to the G-protein signaling field: f作者: Calibrate 時(shí)間: 2025-3-24 04:05
ACTH Resistance Syndromes, has opened a new understanding of the normal and pathologic functioning of the adrenal cortex. This chapter will focus on the clinical forms of hereditary ACTH resistance syndromes and their association with abnormalities of the ACTH receptor gene.作者: brassy 時(shí)間: 2025-3-24 08:32 作者: 聯(lián)邦 時(shí)間: 2025-3-24 13:59
Dopamine Receptors in Human Disease,tems (.). In the central nervous system, dopamine affects locomotion and behavior. In the cardiovascular system, dopamine affects heart rate and myocardial contractility. Dopamine effects on blood pressure and blood volume have been postulated to involve both brainstem and direct renal mechanisms, a作者: rheumatism 時(shí)間: 2025-3-24 15:11 作者: Limerick 時(shí)間: 2025-3-24 19:45
Book 1998 how cells communicate via G-protein-coupled signal transduction processes, but also how defects in these proteins and their receptors can cause serious human disease involving many different organ systems. Written by leading investigators, each chapter describes in detail the structure and function作者: Desert 時(shí)間: 2025-3-25 02:17
Social and Cultural World History theca cells to produce androgen precursors necessary for estrogen synthesis, and on the ovarian follicles to promote ovulation, subsequent corpus luteum formation, and progesterone secretion. Chorionic gonadotropin produced by the placenta acts on the corpus luteum and promotes development of the fetal testes in the first trimester of pregnancy.作者: incredulity 時(shí)間: 2025-3-25 06:19 作者: 誘騙 時(shí)間: 2025-3-25 09:28 作者: NORM 時(shí)間: 2025-3-25 12:26 作者: somnambulism 時(shí)間: 2025-3-25 16:35 作者: 乞討 時(shí)間: 2025-3-25 21:53 作者: farewell 時(shí)間: 2025-3-26 04:11 作者: 評(píng)論者 時(shí)間: 2025-3-26 05:47
Nephrogenic Diabetes Insipidus and Vasopressin Receptor Mutations,jor action of AVP is to facilitate urinary concentration by allowing water to be transported passively down an osmotic gradient between the tubular fluid and the surrounding interstitium. The process of this counter multiplication system and the action of AVP on principal collecting duct cells are represented in Fig. 1.作者: 門(mén)窗的側(cè)柱 時(shí)間: 2025-3-26 09:08
https://doi.org/10.1007/978-3-658-05955-2t hypercal-cemia, is caused by activating mutations in the parathyroid hormone (PTH) PTH-related peptide (PTHrP) receptor. These findings are likely to have significant implications for understanding the biological importance of the PTH/PTHrP receptor in addition to its role in regulating mineral ion homeostasis.作者: 修正案 時(shí)間: 2025-3-26 15:17
,Constitutively Active PTH/PTHrP Receptors Cause Jansen’s Metaphyseal Chondrodysplasia,t hypercal-cemia, is caused by activating mutations in the parathyroid hormone (PTH) PTH-related peptide (PTHrP) receptor. These findings are likely to have significant implications for understanding the biological importance of the PTH/PTHrP receptor in addition to its role in regulating mineral ion homeostasis.作者: Factorable 時(shí)間: 2025-3-26 17:23 作者: ARC 時(shí)間: 2025-3-27 00:46 作者: Flat-Feet 時(shí)間: 2025-3-27 04:54
F.-D. Goebel,U. Kronawitter,J. R. Bognerjor action of AVP is to facilitate urinary concentration by allowing water to be transported passively down an osmotic gradient between the tubular fluid and the surrounding interstitium. The process of this counter multiplication system and the action of AVP on principal collecting duct cells are represented in Fig. 1.作者: 受辱 時(shí)間: 2025-3-27 06:14
21st Century Media and Female Mental Healthrget tissues, and was the first description of a hormone resistance syndrome. Subsequent studies describing parathyroid hyperplasia and elevation of immunoreactive serum PTH in untreated PHP patients confirmed that PTH resistance was the underlying defect ..作者: Oversee 時(shí)間: 2025-3-27 12:08
https://doi.org/10.1007/978-3-658-03392-7through the plasma membrane. Ca. ., in contrast, remains nearly constant, varying by only a few percent under normal circumstances .. Ca. . also has numerous critical funtions, including promoting blood clotting, regulating neuromuscular excitability, and maintaining skeletal integrity.作者: gustation 時(shí)間: 2025-3-27 17:33 作者: Injunction 時(shí)間: 2025-3-27 19:50 作者: PACK 時(shí)間: 2025-3-27 22:52 作者: ATOPY 時(shí)間: 2025-3-28 02:49 作者: Efflorescent 時(shí)間: 2025-3-28 06:47 作者: Commodious 時(shí)間: 2025-3-28 12:57
,The β3-Adrenergic Receptor and Susceptibility to Obesity, the Insulin Resistance Syndrome, and Nonirited diabetes and deafness (MIDD) is the result of mutations in mitochondrial DNA (.). These rare subphenotypes of diabetes are examples in which single gene defects have a major influence on the phenotype and for which environmental influences on expression of the phenotype are negligible.作者: 小故事 時(shí)間: 2025-3-28 17:13
Introduction to G-Protein-Coupled Signal Transduction and Human Disease,er reviews our current understanding of the structure and function of G proteins and the receptors to which they couple, offers some general considerations on how mutations in G proteins and GPCR cause disease, and gives a broad overview of disorders caused by defects in G-protein-coupled signal tra作者: 玩忽職守 時(shí)間: 2025-3-28 22:09 作者: braggadocio 時(shí)間: 2025-3-29 01:43 作者: crockery 時(shí)間: 2025-3-29 05:36
,Gα12- and Gα13-Subunits of Heterotrimeric G-Proteins A Novel Family of Oncogenes,t a common structural motif consisting of the presence of seven transmembrane-spanning domains ., a property that was also predicted for the protein product of the . oncogene on the basis of its nucleotide sequence .. This finding provided the first link between cellular transformation and GPCRs.作者: 侵蝕 時(shí)間: 2025-3-29 11:05
Hypo- and Hyperthyroidism Caused by Mutations of the TSH Receptor,vailability of iodine. Regulation of thyroid function is thus mainly of a “tonic” nature, with virtually no physiological circumstances in which the gland should be put completely at rest. This chapter concentrates on the regulatory actions of thyrotropin via its receptor.作者: adj憂郁的 時(shí)間: 2025-3-29 11:36 作者: 一回合 時(shí)間: 2025-3-29 17:30 作者: 帶來(lái) 時(shí)間: 2025-3-29 21:52
Book 1998 basis of diseases ranging from obesity to malignancy. The basic understanding of the complex signal transduction process achieved here provides a firm foundation for future efforts to prevent and cure these diseases.作者: 侵略 時(shí)間: 2025-3-30 01:16 作者: Harpoon 時(shí)間: 2025-3-30 07:38
Allen M. Spiegel (Chief, Metabolic Diseases Branch作者: 粗糙濫制 時(shí)間: 2025-3-30 09:16 作者: atrophy 時(shí)間: 2025-3-30 13:36 作者: 即席演說(shuō) 時(shí)間: 2025-3-30 19:45 作者: ASTER 時(shí)間: 2025-3-30 21:55
https://doi.org/10.1057/9780230500853t a common structural motif consisting of the presence of seven transmembrane-spanning domains ., a property that was also predicted for the protein product of the . oncogene on the basis of its nucleotide sequence .. This finding provided the first link between cellular transformation and GPCRs.作者: HERE 時(shí)間: 2025-3-31 03:52 作者: PURG 時(shí)間: 2025-3-31 07:25
https://doi.org/10.1007/978-3-322-83518-5d. The purpose of this chapter is to review briefly the structural and functional features of the FSHR, to describe the currently known FSHR mutations, their pathophysiological consequences, and to discuss some future perspectives in the study of the role of FSHR function in reproduction.作者: –吃 時(shí)間: 2025-3-31 12:17 作者: 假裝是我 時(shí)間: 2025-3-31 15:36
978-1-4612-7290-8Springer Science+Business Media New York 1998作者: Fulminate 時(shí)間: 2025-3-31 19:29
G Proteins, Receptors, and Disease978-1-4612-1802-9Series ISSN 2523-3785 Series E-ISSN 2523-3793 作者: 構(gòu)成 時(shí)間: 2025-3-31 23:50 作者: 突襲 時(shí)間: 2025-4-1 05:25
21st Century Media and Female Mental Health characterized by hypocalcemia, hyperphosphatemia, and elevation of serum PTH in the setting of normal renal function, is the major clinical feature. In the original report by Fuller Albright, PHP patients showed reduced calcemic and phosphaturic responses to injected bovine parathyroid extract comp作者: Control-Group 時(shí)間: 2025-4-1 06:42
Alexander F. Barbuto,Peter R. Chaiot only in all vertebrates, but also in invertebrates, such as . and .. G. couples receptors for numerous peptide hormones and monoamines to stimulation of adenylyl cyclase. Although it is now clear that G-protein βγ-subunits can independently modulate adenylyl cyclase (positively or negatively depe作者: Repetitions 時(shí)間: 2025-4-1 12:15
Teachers’ Professional Developmente “inhibitory” G protein. The α-subunit of G. is adenosine diphosphate (ADP)-ribosylated by pertussis toxin and thus functionally uncoupled from the corresponding receptors. Three closely related cDNAs coding for Gα., Gα., and Gα. have been cloned, and the corresponding proteins been identified by s作者: PRE 時(shí)間: 2025-4-1 16:40
US Historical Fiction Since 2000,ssue-specific expression vector that can produce RNA antisense to target mRNA(s). The central role of G proteins in transmembrane signaling from the superfamily of G-protein-linked receptors (GPLRs) to a less populous class of effector molecules that includes adenyl cyclase, phospholipase C (PLC), a作者: 協(xié)議 時(shí)間: 2025-4-1 20:37
