標(biāo)題: Titlebook [打印本頁] 作者: angiotensin-I 時間: 2025-3-21 18:27 作者: pester 時間: 2025-3-21 22:51
Exact and Approximate Aggregation,entation, and their ability to express costimulatory molecules. We will also discuss astrocytes as the major CNS producers of several chemokines and cytokines, and their relevance to neurological disease.作者: 易受刺激 時間: 2025-3-22 01:54
The Role of Astrocytes in Autoimmune Disease of the Central Nervous Systementation, and their ability to express costimulatory molecules. We will also discuss astrocytes as the major CNS producers of several chemokines and cytokines, and their relevance to neurological disease.作者: ear-canal 時間: 2025-3-22 04:54 作者: 無可非議 時間: 2025-3-22 12:47
Suraj Kedarisetty,Ahmed M. S. Solimanddressing chemokine expression in multiple sclerosis. These results resemble results obtained earlier in EAE. Taken together, these data suggest that chemokine system may be a promising target for future treatment methods of multiple sclerosis.作者: Morose 時間: 2025-3-22 15:01 作者: Morose 時間: 2025-3-22 20:35 作者: CHOP 時間: 2025-3-23 01:01
https://doi.org/10.1007/978-3-319-97478-1 including collection and processing of appropriate samples and a review of grading systems that have been used to quantify the histopathological changes. The specific histopathological features of EAE are described with reference to selected model systems including the SJL/J, C57B1/6 and NOD mouse, the Lewis rat, rhesus monkey and marmoset.作者: 可行 時間: 2025-3-23 04:49
On Linear Logic of Knowledge and Time,ed with technological refinements in cellular immunology, is allowing us to ask important questions about the generation and control of the autoreactive T cell repertoire. This information also provides the basis for models of how these cells become activated and for advances in antigen-specific therapeutic intervention.作者: Entirety 時間: 2025-3-23 08:20
Histopathology of EAE including collection and processing of appropriate samples and a review of grading systems that have been used to quantify the histopathological changes. The specific histopathological features of EAE are described with reference to selected model systems including the SJL/J, C57B1/6 and NOD mouse, the Lewis rat, rhesus monkey and marmoset.作者: doxazosin 時間: 2025-3-23 13:03
T Lymphocytes in EAEed with technological refinements in cellular immunology, is allowing us to ask important questions about the generation and control of the autoreactive T cell repertoire. This information also provides the basis for models of how these cells become activated and for advances in antigen-specific therapeutic intervention.作者: 階層 時間: 2025-3-23 15:33
Induction of EAEific for myelin-associated autoantigens of the central nervous system (CNS). This chapter presents an overview of some useful strategies and protocols by which EAE can be induced, and discusses the pros and cons of various approaches.作者: 小丑 時間: 2025-3-23 19:41 作者: 幼兒 時間: 2025-3-23 23:56 作者: 尖酸一點 時間: 2025-3-24 03:52
Electrode Preparation Exploiting Filtratione cells in the normal brain and their contribution to inflammatory demyelinating disease, including their role in antigen presentation, co-stimulation, and production of cytokines and other inflammatory mediators作者: ALIEN 時間: 2025-3-24 10:06 作者: 生氣地 時間: 2025-3-24 13:30 作者: BRACE 時間: 2025-3-24 15:35 作者: oxidize 時間: 2025-3-24 20:40 作者: 上漲 時間: 2025-3-25 01:12 作者: SOW 時間: 2025-3-25 06:53
The Neuron and Axon in Experimental Autoimmune EncephalomyelitisEAE, these processes are being investigated in great detail. This chapters discusses the present knowledge of axonal and neuronal pathology in MS and details the relevant studies in EAE, that may form the basis to future neuroprotective/regenerative approaches to MS.作者: Dorsal 時間: 2025-3-25 09:47 作者: 錯 時間: 2025-3-25 14:59 作者: Incompetent 時間: 2025-3-25 19:04
Cross-View Image Geo-localization in combination with different types of adjuvant. The second approach of inducing EAE consists in adoptive transfer of activated T cells that are specific for myelin-associated autoantigens of the central nervous system (CNS). This chapter presents an overview of some useful strategies and protocols作者: A保存的 時間: 2025-3-25 21:54 作者: Rotator-Cuff 時間: 2025-3-26 00:33 作者: Angiogenesis 時間: 2025-3-26 06:59 作者: NATTY 時間: 2025-3-26 12:05 作者: machination 時間: 2025-3-26 14:00 作者: monochromatic 時間: 2025-3-26 19:45
Morphology of Selected Families,ctivation, cells of the immune system undergo changes that allow for an immune response within the CNS. The animal model, experimental autoimmune encephalomyelitis (EAE), is an important tool by which to investigate these processes. Using EAE, it has been shown that the establishment of an immune re作者: 揮舞 時間: 2025-3-26 22:33
https://doi.org/10.1007/978-3-662-03766-9new therapeutic strategies in human diseases, such as multiple sclerosis. This is not easily accomplished as significant heterogeneity exists and such genetic dissection may more easily be performed using inbred rodent strains, where the genetic heterogeneity is avoided and variation in the environm作者: output 時間: 2025-3-27 02:37
On Linear Logic of Knowledge and Time,also contribute to pathology. The recovery phase of the disease poses more of a challenge with the potential for various regulatory T cell populations to halt the pathology. We know a good deal about the fine-specificity of T cell recognition of epitopes derived from myelin autoantigens. This, coupl作者: 護(hù)航艦 時間: 2025-3-27 06:14 作者: 步兵 時間: 2025-3-27 10:16 作者: 極少 時間: 2025-3-27 13:47 作者: 不容置疑 時間: 2025-3-27 17:58
Suraj Kedarisetty,Ahmed M. S. Solimanth recruited and resident inflammatory cells. Chemokines act on target cells through G-protein-coupled seven-transmembrane-domain receptors. High expression of several chemokines was found in the CNS during EAE. Cells expressing these chemokines were predominantly astrocytes and macrophages/microgli作者: 詢問 時間: 2025-3-27 22:17
Peripheral and Central Hypersensitivity ONOO- species is discussed and the current literature EAE reviewed. The dual nature of free radicals, pathogenic and protective, and the correspondingly conflicting results of therapeutic interventions aimed at diminishing free radicals (in particular reactive nitrogen species), are also discussed 作者: 變化無常 時間: 2025-3-28 05:33
J. Willebrand,D. L. T. AndersonEAE is a useful animal model of autoimmune disease of the central nervous system. In this chapter we discuss the history of EAE, including the original description of the model and the subsequent major developments, and then describe the usual clinical signs and disease course.作者: reject 時間: 2025-3-28 07:44 作者: 側(cè)面左右 時間: 2025-3-28 12:13
https://doi.org/10.1007/978-3-030-53472-1EAE is a T cell mediated disease, but increasing evidence shows an important role for B cells and antibodies in its pathogenesis. This also reflects a role for humoral factors in the pathogenesis of multiple sclerosis. The main functions of B cells and antibodies in EAE are discussed.作者: Gustatory 時間: 2025-3-28 17:14 作者: EXUDE 時間: 2025-3-28 20:54
EAE: History, Clinical Signs, and Disease CourseEAE is a useful animal model of autoimmune disease of the central nervous system. In this chapter we discuss the history of EAE, including the original description of the model and the subsequent major developments, and then describe the usual clinical signs and disease course.作者: Servile 時間: 2025-3-28 23:50
Neuroantigens in EAEThis chapter reviews briefly the biology of myelin and describes the major CNS myelin proteins, the potential neuroantigens in EAE. The genetics of the principal myelin proteins are also discussed. Myelin glycolipids with potential role in CNS demyelinating disease and the enzymes involved in their synthesis are also reviewed.作者: 發(fā)誓放棄 時間: 2025-3-29 05:29
B Cells and Antibodies in Experimental Autoimmune EncephalomyelitisEAE is a T cell mediated disease, but increasing evidence shows an important role for B cells and antibodies in its pathogenesis. This also reflects a role for humoral factors in the pathogenesis of multiple sclerosis. The main functions of B cells and antibodies in EAE are discussed.作者: ablate 時間: 2025-3-29 08:27
The Role of Growth Factors in Experimental Autoimmune EncephalomyelitisThis chapter reviews the research done on the role of growth factor in experimental autoimmune encephalomyelitis and demonstrates the increasingly recognized therapeutic potential of growth factors in inflammatory demyelinating disease.作者: BARK 時間: 2025-3-29 13:06 作者: 貪婪性 時間: 2025-3-29 17:39 作者: 分發(fā) 時間: 2025-3-29 20:55
Adjuvants in EAE cell-mediated immunity, including EAE. An additional adjuvant, pertussis toxin, is necessary for active EAE in mice. The mechanisms of action of adjuvants are multiple, but important actions are stimulation of proinflammatory cytokines and costimulatory molecules.作者: Aspiration 時間: 2025-3-30 02:28
The Role of Astrocytes in Autoimmune Disease of the Central Nervous Systemf astrocytes includes the formation and maintenance of the blood brain barrier (BBB), and the supply of structural support and nourishment to neurons. This article will discuss the role of astrocytes in multiple sclerosis (MS) and other inflammatory autoimmune diseases of the CNS. We will address th作者: prostate-gland 時間: 2025-3-30 07:07
Role of Microglia and Macrophages in Eaee cells in the normal brain and their contribution to inflammatory demyelinating disease, including their role in antigen presentation, co-stimulation, and production of cytokines and other inflammatory mediators作者: 使尷尬 時間: 2025-3-30 08:53 作者: HPA533 時間: 2025-3-30 13:33
Endothelial Cells and Adhesion Molecules in Experimental Autoimmune Encephalomyelitisctivation, cells of the immune system undergo changes that allow for an immune response within the CNS. The animal model, experimental autoimmune encephalomyelitis (EAE), is an important tool by which to investigate these processes. Using EAE, it has been shown that the establishment of an immune re作者: neutralize 時間: 2025-3-30 17:54 作者: 小步走路 時間: 2025-3-30 20:55 作者: seduce 時間: 2025-3-31 03:15 作者: JOT 時間: 2025-3-31 08:07
Cytokines in Experimental Autoimmune Encephalomyelitisoinflammatory and anti-inflammatory cytokines and their role in EAE, as shown by expression in nervous tissue, production by cells of the immune and nervous system, experiments with exogenous administration, overexpression, antibody neutralization or knockout mice.作者: Parameter 時間: 2025-3-31 12:31 作者: Fecal-Impaction 時間: 2025-3-31 14:01 作者: 豐富 時間: 2025-3-31 19:39 作者: 制定 時間: 2025-3-31 22:36 作者: Nucleate 時間: 2025-4-1 03:55 作者: 有說服力 時間: 2025-4-1 09:38
https://doi.org/10.1007/978-3-030-61856-8 with clinical observations, and studies in the animal model have contributed to providing possible explanations for these beneficial effects..Our review also covers a limited number of studies on the apparently beneficial effect of treatment with another Type I interferon, namely IFN-τ, originally 作者: Macronutrients 時間: 2025-4-1 13:50
Genetics of Experimental Allergic Encephalomyelitiscomplex allotypes, which in EAE is in response to induction with certain myelin antigens. Both are complex polygenic diseases where disease traits are controlled by a number of polymorphic genes which individually exhibiting modest effect on disease course. A number of as yet largely unknown genes,
