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標(biāo)題: Titlebook: Experimental and Clinical Effects of L-Asparaginase; International Sympos E. Grundmann,H. F. Oettgen Book 1970 Springer-Verlag Berlin ? Hei [打印本頁(yè)]

作者: Scuttle    時(shí)間: 2025-3-21 17:02
書目名稱Experimental and Clinical Effects of L-Asparaginase影響因子(影響力)




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書目名稱Experimental and Clinical Effects of L-Asparaginase被引頻次




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書目名稱Experimental and Clinical Effects of L-Asparaginase年度引用




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書目名稱Experimental and Clinical Effects of L-Asparaginase讀者反饋




書目名稱Experimental and Clinical Effects of L-Asparaginase讀者反饋學(xué)科排名





作者: 稱贊    時(shí)間: 2025-3-21 20:50

作者: VERT    時(shí)間: 2025-3-22 01:15
Experimental and Clinical Effects of L-Asparaginase978-3-642-99984-0Series ISSN 0080-0015 Series E-ISSN 2197-6767
作者: obscurity    時(shí)間: 2025-3-22 07:42
0080-0015 Overview: 978-3-642-99986-4978-3-642-99984-0Series ISSN 0080-0015 Series E-ISSN 2197-6767
作者: arbovirus    時(shí)間: 2025-3-22 12:39

作者: Generalize    時(shí)間: 2025-3-22 16:25
Ungleichheitsaversion und Fairness,. has described some of his observations on the effect of guinea pig serum in inhibiting the growth of certain mouse tumors, and out of this apparently distant finding we are engaged in the present symposium [1].
作者: Generalize    時(shí)間: 2025-3-22 20:45
,Die Unaussprechlichen – PAK, PCB, Dioxine…,In summer of 1967 the first reports of remissions of acute leukemia in patients treated with L-asparaginase extracted from E. coli were published in the USA [9]. But these were only rare cases owing to the scarcity of the pure enzyme. It was therefore necessary to develop a technical process for the production of the enzyme.
作者: Pudendal-Nerve    時(shí)間: 2025-3-23 00:59
https://doi.org/10.1007/978-3-031-22795-0To obtain further information on the properties and structure of L-asparaginase, highly purified, crystalline enzyme preparations were used for the following investigations.
作者: 指派    時(shí)間: 2025-3-23 02:52

作者: 內(nèi)閣    時(shí)間: 2025-3-23 06:23

作者: 使激動(dòng)    時(shí)間: 2025-3-23 13:19
Biochemical Characterization of L-Asparaginases from E. coliTo obtain further information on the properties and structure of L-asparaginase, highly purified, crystalline enzyme preparations were used for the following investigations.
作者: 同步左右    時(shí)間: 2025-3-23 17:50

作者: ingestion    時(shí)間: 2025-3-23 19:28

作者: 不公開    時(shí)間: 2025-3-24 01:23
https://doi.org/10.1007/978-981-10-6701-3cells has been the subject of numerous presentations at this symposium. The purpose of this report is to describe an automated method for the assay of L-asparaginase and to present data concerning the distribution and clearance of administered L-asparaginase.
作者: 飛鏢    時(shí)間: 2025-3-24 03:11
Advances in Creativity and Giftednessnt for its characterization, but that as much as possible should be known about its fate in the body — i. e. absorption, blood levels, distribution, elimination, and biotransformation. In the case of Crasnitin . this is of special importance because therapy with enzymes is a rather new field of mode
作者: cliche    時(shí)間: 2025-3-24 08:08

作者: STIT    時(shí)間: 2025-3-24 12:29
https://doi.org/10.1007/978-981-97-1598-5ce of a non-cytopathic, and otherwise benign replicating agent as an adjunct in asparaginase therapy was somewhat unexpected and to our knowledge has no theoretical antecedent. This virus is variously known as the lactate dehydrogenase-elevating virus, the LDH-virus, the enzymes-elevating virus and
作者: Leisureliness    時(shí)間: 2025-3-24 18:05

作者: 連累    時(shí)間: 2025-3-24 21:01

作者: Bravura    時(shí)間: 2025-3-25 02:18
Sheldon, Pastor and His People,e lost the ability to synthesize L-asparagine and thus depend on the exogenous supply of this amino acid. Yet it is not always sufficiently considered that E. coli asparaginase also possesses a small amount of L-glutaminase activity [1] and in high dosage may become effective by depriving the cells
作者: FLAT    時(shí)間: 2025-3-25 06:49
Sheldon, Pastor and His People,] and are predominantly of lymphatic or hematopoeitic origin. Rarely, other tumor types, including a rat fibrosarcoma [8], a mouse mammary carcinoma [15], and two cases of human malignant melanoma [6, 12] may be suppressed by treatment with asparaginase.
作者: Acquired    時(shí)間: 2025-3-25 07:51

作者: 貿(mào)易    時(shí)間: 2025-3-25 13:51
Gilbert and Sullivan‘s ‘Respectable Capers‘ host reactions to this disease (. et al., 1969). In these studies the patient’s own serum was added to the tumour cells . and the existence of complement-dependent autoantibodies to some melanomas was demonstrated. To test if melanoma cells were sensitive to L-asparaginase, the cells were treated i
作者: 傲慢物    時(shí)間: 2025-3-25 16:32
Travelling Inwards: D. H. Lawrence, in mice treated with high doses of the enzymepreparation. . described inhibition of the graft-versus-host reaction in mice and rats receiving E. coli L-asparaginase [8]. Suppression of phytohemagglutinin-induced transformation of human lymphocytes was reported by . et al. [1] and by . [12].
作者: BALE    時(shí)間: 2025-3-25 22:35
Deleuze and the Film in His Mindce of resistance in mice bearing a leukemia which is sensitive to the drug (. and ., 1969) (personal unpublished findings); secondly, L-asparaginase shows immunosuppressive activities in a number of tests.
作者: CHARM    時(shí)間: 2025-3-26 02:12

作者: Type-1-Diabetes    時(shí)間: 2025-3-26 07:14

作者: OCTO    時(shí)間: 2025-3-26 08:29
Sheldon, Pastor and His People,e lost the ability to synthesize L-asparagine and thus depend on the exogenous supply of this amino acid. Yet it is not always sufficiently considered that E. coli asparaginase also possesses a small amount of L-glutaminase activity [1] and in high dosage may become effective by depriving the cells of L-glutamine.
作者: 流行    時(shí)間: 2025-3-26 15:45
Sheldon, Pastor and His People,] and are predominantly of lymphatic or hematopoeitic origin. Rarely, other tumor types, including a rat fibrosarcoma [8], a mouse mammary carcinoma [15], and two cases of human malignant melanoma [6, 12] may be suppressed by treatment with asparaginase.
作者: 新星    時(shí)間: 2025-3-26 18:59
Travelling Inwards: D. H. Lawrence, in mice treated with high doses of the enzymepreparation. . described inhibition of the graft-versus-host reaction in mice and rats receiving E. coli L-asparaginase [8]. Suppression of phytohemagglutinin-induced transformation of human lymphocytes was reported by . et al. [1] and by . [12].
作者: LUDE    時(shí)間: 2025-3-26 21:13

作者: 死亡率    時(shí)間: 2025-3-27 05:05
The Distribution and Clearance of L-Asparaginasecells has been the subject of numerous presentations at this symposium. The purpose of this report is to describe an automated method for the assay of L-asparaginase and to present data concerning the distribution and clearance of administered L-asparaginase.
作者: 搬運(yùn)工    時(shí)間: 2025-3-27 05:28
Critical Influence of an Enzyme-Elevating Virus upon Long-Term Remissions of Mouse Leukemia Followince of a non-cytopathic, and otherwise benign replicating agent as an adjunct in asparaginase therapy was somewhat unexpected and to our knowledge has no theoretical antecedent. This virus is variously known as the lactate dehydrogenase-elevating virus, the LDH-virus, the enzymes-elevating virus and by other designations [65, 671].
作者: 燕麥    時(shí)間: 2025-3-27 12:43
Studies on the Glutaminase Activity of E. coli Asparaginase in Tissue Culturee lost the ability to synthesize L-asparagine and thus depend on the exogenous supply of this amino acid. Yet it is not always sufficiently considered that E. coli asparaginase also possesses a small amount of L-glutaminase activity [1] and in high dosage may become effective by depriving the cells of L-glutamine.
作者: 高腳酒杯    時(shí)間: 2025-3-27 13:43

作者: 裁決    時(shí)間: 2025-3-27 21:40
Influence of L-Asparaginase Preparations of E. coli and Agouti Serum on the Homograft Reactivity in in mice treated with high doses of the enzymepreparation. . described inhibition of the graft-versus-host reaction in mice and rats receiving E. coli L-asparaginase [8]. Suppression of phytohemagglutinin-induced transformation of human lymphocytes was reported by . et al. [1] and by . [12].
作者: opportune    時(shí)間: 2025-3-27 22:24

作者: 全神貫注于    時(shí)間: 2025-3-28 04:18

作者: yohimbine    時(shí)間: 2025-3-28 09:34
Experimental Investigations on Problems of the Clinical Use of L-Asparaginaseuseful to study experimentally problems which arose from the clinical use of the enzyme. Consequently we investigated the influence of the following factors on tumor inhibition: dosage, duration of treatment, treatment schedules, treatment of Crasnitin resistant tumors, combined treatment with Crasnitin, and immunological factors in enzyme therapy.
作者: 索賠    時(shí)間: 2025-3-28 11:04
https://doi.org/10.1057/9780230228436 reversibility of the antileukemic effect of A-ase . and ., the effects of dose and dosage schedule on early and advanced ascitic, subcutaneous, and intracerebral leukemia, and the effect of prior or concomitant treatment with other chemotherapeutic agents on both the half-life of the drug and the i
作者: 溝通    時(shí)間: 2025-3-28 15:05
Experimental Studies with L-Asparaginase in Mouse Leukemias reversibility of the antileukemic effect of A-ase . and ., the effects of dose and dosage schedule on early and advanced ascitic, subcutaneous, and intracerebral leukemia, and the effect of prior or concomitant treatment with other chemotherapeutic agents on both the half-life of the drug and the i
作者: 真實(shí)的你    時(shí)間: 2025-3-28 21:03

作者: commute    時(shí)間: 2025-3-29 00:38

作者: patriarch    時(shí)間: 2025-3-29 03:58
The Distribution and Clearance of L-Asparaginasecells has been the subject of numerous presentations at this symposium. The purpose of this report is to describe an automated method for the assay of L-asparaginase and to present data concerning the distribution and clearance of administered L-asparaginase.
作者: Magnificent    時(shí)間: 2025-3-29 07:27
Pharmacokinetic Behavior of L-Asparaginase in Men and in Animalsnt for its characterization, but that as much as possible should be known about its fate in the body — i. e. absorption, blood levels, distribution, elimination, and biotransformation. In the case of Crasnitin . this is of special importance because therapy with enzymes is a rather new field of mode
作者: 省略    時(shí)間: 2025-3-29 15:27

作者: 施魔法    時(shí)間: 2025-3-29 16:36

作者: 在前面    時(shí)間: 2025-3-29 23:36
Experimental Studies with L-Asparaginase in Mouse Leukemiasand later as preparations of varying degrees of purity from ., showed it to be a unique agent with a very high chemotherapeutic index which is capable of curing some mouse leukemias and tumors at high doses without assistance from host immune mechanisms. Since the drug also has a similar chemotherap
作者: VEN    時(shí)間: 2025-3-30 02:47
Experimental Investigations on Problems of the Clinical Use of L-Asparaginaseuseful to study experimentally problems which arose from the clinical use of the enzyme. Consequently we investigated the influence of the following factors on tumor inhibition: dosage, duration of treatment, treatment schedules, treatment of Crasnitin resistant tumors, combined treatment with Crasn
作者: 附錄    時(shí)間: 2025-3-30 06:37
Studies on the Glutaminase Activity of E. coli Asparaginase in Tissue Culturee lost the ability to synthesize L-asparagine and thus depend on the exogenous supply of this amino acid. Yet it is not always sufficiently considered that E. coli asparaginase also possesses a small amount of L-glutaminase activity [1] and in high dosage may become effective by depriving the cells
作者: ingenue    時(shí)間: 2025-3-30 08:47

作者: 鎮(zhèn)痛劑    時(shí)間: 2025-3-30 16:05

作者: 善辯    時(shí)間: 2025-3-30 17:33

作者: senile-dementia    時(shí)間: 2025-3-30 21:54

作者: Genetics    時(shí)間: 2025-3-31 03:26

作者: 吹牛大王    時(shí)間: 2025-3-31 08:59

作者: Minikin    時(shí)間: 2025-3-31 11:02
Inhibitation by L-Asparaginase from E. coli of Human Malignant Melanoma Cells Growing in vitroment-dependent autoantibodies to some melanomas was demonstrated. To test if melanoma cells were sensitive to L-asparaginase, the cells were treated in exactly the same way except that instead of autologous serum . L-asparaginase from Bayer was added to the cultures.
作者: cardiopulmonary    時(shí)間: 2025-3-31 16:17

作者: 黃瓜    時(shí)間: 2025-3-31 17:35
Gilbert and Sullivan‘s ‘Respectable Capers‘ment-dependent autoantibodies to some melanomas was demonstrated. To test if melanoma cells were sensitive to L-asparaginase, the cells were treated in exactly the same way except that instead of autologous serum . L-asparaginase from Bayer was added to the cultures.
作者: –FER    時(shí)間: 2025-3-31 23:00

作者: Hyperopia    時(shí)間: 2025-4-1 05:43





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