作者: 低能兒 時間: 2025-3-21 23:21 作者: instulate 時間: 2025-3-22 02:16 作者: NOTCH 時間: 2025-3-22 07:31
Genome Mapping and Genomics in Animals, the carcinogenic process can either evolve naturally or operationally be modulated. The factors that modulate an initiated carcinogenesis can have positive or negative effects. When the incidence and/ or the yield of cancer is increased and/or the latency period is decreased by the modulating trea作者: indenture 時間: 2025-3-22 09:32
Genome Mapping and Genomics in Animalsty (2), enzymatic competence of tissue(s) to activate the procarcinogen (3–5), the interaction of ultimate carcinogenic moiety with specific macromolecular site(s) (6,7), the rate of removal of the formed adduct(s) (8), the degree of macromolecular repair (9,10), caloric intake (11–13), immune compe作者: 機(jī)構(gòu) 時間: 2025-3-22 13:02
Katherine M. Buckley,Jonathan P. Rastd with PHC are different in low incidence areas of the world such as Europe and U.S.A. /Friedman, 1983; Lapis and Johannessen, 1979; Sandler et al., 1983; Schaff et al., 1971/ and in high incidence areas, such as sub-Saharan Africa /Anthony et al., 1973; Kew, 1978; Szmuness, 1978/, Southeast Asia /C作者: 機(jī)構(gòu) 時間: 2025-3-22 17:09 作者: 不開心 時間: 2025-3-22 22:35 作者: Accomplish 時間: 2025-3-23 05:20
NATO Science Partnership Subseries: 3ation, localization and quantification of specific substances, reactive groups and sites of enzymatic activities in tissues, cells and cell organelles. Principally metabolic products or enzymes can also be assessed by biochemical analysis nowadays much more efficiently because of the development of 作者: oblique 時間: 2025-3-23 06:14 作者: patriarch 時間: 2025-3-23 12:33 作者: 不確定 時間: 2025-3-23 16:31
https://doi.org/10.1007/978-1-0716-2237-7CPA), phenobarbital (PB) or various other lipophilic compounds have been found to produce liver tumors in long-term animal experiments, although they do not exhibit detectable genotoxic activity. Studies on the mechanisms of action of such nongenotoxic hepatocarcinogens revealed that these with resp作者: Highbrow 時間: 2025-3-23 18:27 作者: 易受刺激 時間: 2025-3-24 00:33 作者: 附錄 時間: 2025-3-24 04:43
Wim H. J. Vanhouten,Sally A. Mackenzieve physiological compound of plasma membranes, it is believed that intermediate molecules of its metabolism are directly implied with DNA synthesis (2). Several experimental reports support these assumptions. The following general considerations can be recalled:作者: CURB 時間: 2025-3-24 08:26
978-1-4612-8264-8Plenum Press, New York 1988作者: 食料 時間: 2025-3-24 11:00 作者: 自然環(huán)境 時間: 2025-3-24 16:09
Cholesterol Metabolism During Cell Proliferationve physiological compound of plasma membranes, it is believed that intermediate molecules of its metabolism are directly implied with DNA synthesis (2). Several experimental reports support these assumptions. The following general considerations can be recalled:作者: aristocracy 時間: 2025-3-24 20:04
http://image.papertrans.cn/e/image/318844.jpg作者: misanthrope 時間: 2025-3-25 02:05 作者: 凹室 時間: 2025-3-25 06:20 作者: 憎惡 時間: 2025-3-25 11:10 作者: persistence 時間: 2025-3-25 13:24
The Induction of Localized Tumours by Carcinogens Implanted into the Livercute liver cell damage and necrosis and therefore would minimize or obviate the subsequent connective tissue proliferation. With luck, it was reasoned, the presence of a persisting depot of carcinogenic material would in time also lead to the development of tumours, as had been shown to be the case in other organs.作者: 幻想 時間: 2025-3-25 19:27 作者: 安裝 時間: 2025-3-25 21:04
Catherine W. Ernst,A. Marcos Ramosngle step protocols do exist for the chemical induction of cancer using large doses of carcinogen, most of the protocols which are classically used for that purpose are multisteps in that sense that they involve a sequence of different treatments.作者: Distribution 時間: 2025-3-26 01:06
https://doi.org/10.1007/978-1-0716-2237-7ytes. These changes are thought to reflect an adaptive program in the liver that is switched on consequently to the increased functional demands on the organ (Conney et al. 1960; Argyris and Magnus 1968; Schlicht et al. 1967, 1968; Koransky et al. 1969; Schulte-Hermann 1974; Schulte-Hermann et al. 1980a,b).作者: 消散 時間: 2025-3-26 06:18 作者: 容易做 時間: 2025-3-26 11:30 作者: FLAG 時間: 2025-3-26 13:48
out 100 scientists, mostly from Europe but also from the United States, met there for three days in a very friendly atmosphere to exchange knowledge and ideas on experimental and human liver carcinogenesis. The main topics discussed during the meeting included general reviews on hepatocarcinogenesis作者: 存在主義 時間: 2025-3-26 17:43
Genome Instability in Cancer Development different chemical nature. In experimental animals, mostly the rat and the mouse, quite a number of diverse chemicals have been demonstrated to produce liver tumors. Accordingly, such chemicals are called hepatocarcinogens.作者: Thyroid-Gland 時間: 2025-3-27 00:21 作者: 心胸狹窄 時間: 2025-3-27 01:49 作者: Maximize 時間: 2025-3-27 08:14
Structure and Organization of Virus Genomes,ation. This is apparently true for the development of all kinds of malignant tumors, induced by physical, chemical or viral factors, and applies also to hepatocarcinogenesis. This contribution is aimed at dissecting some critical phases of the carcinogenic process in the liver with respect to cell proliferation.作者: 一窩小鳥 時間: 2025-3-27 11:38 作者: critique 時間: 2025-3-27 17:03
Genome Mapping and Genomics in Animalstment, the modulation is considered as positive whereas a treatment which decreases the incidence and/or the yield of cancer and/or increases the latency period is considered as a negative modulator. (Roberfroid, 1987)作者: 失誤 時間: 2025-3-27 18:34
Modulating Factors of Hepatocarcinogenesistment, the modulation is considered as positive whereas a treatment which decreases the incidence and/or the yield of cancer and/or increases the latency period is considered as a negative modulator. (Roberfroid, 1987)作者: osteopath 時間: 2025-3-28 00:23
Hepatocarcinogens different chemical nature. In experimental animals, mostly the rat and the mouse, quite a number of diverse chemicals have been demonstrated to produce liver tumors. Accordingly, such chemicals are called hepatocarcinogens.作者: 思考才皺眉 時間: 2025-3-28 06:00 作者: 辭職 時間: 2025-3-28 10:16 作者: 擴(kuò)張 時間: 2025-3-28 14:20 作者: FLIT 時間: 2025-3-28 15:27
Hepatocarcinogensociated more directly with the development of these tumors in man. Among them are: aflatoxins, cycasin, vinyl chloride, and estrogens, agents of quite different chemical nature. In experimental animals, mostly the rat and the mouse, quite a number of diverse chemicals have been demonstrated to produ作者: SPURN 時間: 2025-3-28 21:46
The Induction of Localized Tumours by Carcinogens Implanted into the Liver process of fibrogenesis and scarring in the liver — the result of toxic injury caused by the rather large doses of hepatocarcinogens then used — from the phenomenon of hepatocarcinogenesis proper. It was assumed that the implantation of known hepatocarcinogens into the liver would lead only to a gr作者: Provenance 時間: 2025-3-29 01:08
Two Stage Theory of Carcinogenesis: A Critical Review Introducing the Concept of Modulationt event which introduces the tissue or some of its cells into that process. That event may be a physical (radiation) or a chemical mostly mutagenic treatment but also a viral infection or even a transfection of a piece of viral DNA (Lacey et al.1986). In most experimental protocols reported so far f作者: Expurgate 時間: 2025-3-29 05:10
Modulating Factors of Hepatocarcinogenesis, the carcinogenic process can either evolve naturally or operationally be modulated. The factors that modulate an initiated carcinogenesis can have positive or negative effects. When the incidence and/ or the yield of cancer is increased and/or the latency period is decreased by the modulating trea作者: 形上升才刺激 時間: 2025-3-29 07:34
Sex Hormones as Modulators of Liver Tumor Developmentty (2), enzymatic competence of tissue(s) to activate the procarcinogen (3–5), the interaction of ultimate carcinogenic moiety with specific macromolecular site(s) (6,7), the rate of removal of the formed adduct(s) (8), the degree of macromolecular repair (9,10), caloric intake (11–13), immune compe作者: STANT 時間: 2025-3-29 14:25 作者: conquer 時間: 2025-3-29 18:17 作者: 原始 時間: 2025-3-29 23:17
Cellular Differentiation During Neoplastic Development in the Liverormal counterparts. Thus, hepatocellular, cholangiocellular and diverse mesenchymal tumors are distinguished. This histogenetic classification was established by light microscopy. It has been supported by many electron microscopical results and more recently also by immunohistochemical investigation
