作者: Nonconformist 時間: 2025-3-21 22:26 作者: reject 時間: 2025-3-22 03:11
https://doi.org/10.1007/978-3-662-31585-9hate (InsP3). DAG activates protein kinase C (PK-C) and InsP3 mobilizes intracellular calcium. Both tumor promoting phorbol esters (TPA) which activate PK-C directly and calcium ionophores which mobilize intracellular calcium bypass inositol phospholipid breakdown. We recently reported that the inte作者: Fortify 時間: 2025-3-22 08:33
Differenzierung im postretinalen Bereich,ifferent regions of haemopoietic tissue. In the leg shielding experiments, cellularity, spleen colony-forming unit (CFU-S) content and proliferative activity return to normal in the shielded limb long before they do in the rest of the animal. (5). Following phenylhydrazine (PHZ), demand for erythroi作者: Project 時間: 2025-3-22 12:00
https://doi.org/10.1007/978-3-642-45812-5rogeny which can differentiate along lineage-specific pathways. Although much is known about the humoral factors involved in regulating the proliferation and differentiation of committed hematopoietic progenitor cells, the role of humoral factors in the proliferation of pluripotent hematopoietic ste作者: 通便 時間: 2025-3-22 16:42 作者: 通便 時間: 2025-3-22 19:28
https://doi.org/10.1007/978-3-642-71505-1ssay is still not sufficient to detect normal circulating levels of Ep; these have been established by radioimmunoassay to be 9.7 to 24.8 mUnits/ml of serum [2]. All previous efforts at concentrating human serum prior to assaying its biologically active Ep content have resulted in the loss of some a作者: nutrition 時間: 2025-3-22 23:11
Gholamali Tariverdian,Marion Paulutant. The etiology has been presumed due to a defect in the ability the marrow stem cells to differentiate into normally functioning osteoclasts. Data are not available to prove that replacing only the osteoclast precursor (an unidentified cell) will cure the disorder. To test whether marrow stroma作者: 表皮 時間: 2025-3-23 04:05
https://doi.org/10.1007/978-3-642-46885-8onstrated by the presence of collagen types I and III and fibronectin, and the absence of collagen type IV and laminin. Three antibodies to these fibroblastoid cells exclusively recognized hemopoietic stromal cells in splenic red pulp and bone marrow of adult mice, with the exception of the occasion作者: 使饑餓 時間: 2025-3-23 09:29
S. Granick,K. Egle,Kurt Steffenf the stromal tissue which controls hemopoiesis (1–7). It has been, however, impossible to determine conclusively which of the stromal cell types comprising this complex microenvironment tissue is mediating the observed functions. The requirement for pure cell populations for any further experimenta作者: 辯論 時間: 2025-3-23 12:15 作者: 膽小鬼 時間: 2025-3-23 16:44 作者: 祝賀 時間: 2025-3-23 20:40 作者: Cursory 時間: 2025-3-24 00:43
Kapitel 2: Der Enhancement-Begriffd acute lymphoblastic leukemia (ALL) is generally classified into the following major subgroups: T-ALL, B-ALL and common ALL (cALL) (1). Not infrequently, however, it is impossible to classify acute leukemias as B or T cell or nonlymphoid in origin despite examining lineage associated surface marker作者: 聽覺 時間: 2025-3-24 06:15
Medizinethische Aspekte der Sucht,an leukemia cells. In this study we report our findings, using this combined approach, in the different forms of acute and chronic leukemia. All cases of common acute lymphoblastic leukemia (cALL) studied showed (with only one exception) a heavy chain Ig gene rearrangement; a light chain gene reorga作者: minaret 時間: 2025-3-24 07:02
,Von St?mmen, St?ngeln und Stielen,ula except KG-1 consistently grew nonmet-astatic subcutaneous (sc) tumors after 3 weeks. Cytologic, immuno- and enzyme-cytochemical tests proved identity of respective tumor and cultured cells. Adenosine triphosphatase (ATPase) reactivity was limited to tumorigenie cells in vivo, while leucine amino作者: 熱心助人 時間: 2025-3-24 11:34 作者: 表示向下 時間: 2025-3-24 16:40 作者: 衰弱的心 時間: 2025-3-24 20:12
https://doi.org/10.1007/978-1-4612-4920-7bone marrow; hematology; hematopoiesis; transplantation作者: 問到了燒瓶 時間: 2025-3-25 02:26
Geniale Frauen in der WissenschaftThe four previous articles in this series reviewed prinicples of modern molecular biology in the context of hematologic disorders. In this final review, we consider recent insights into the molecular basis of chronic myelogenous leukemia (CML) resulting from the use of these technics.作者: circuit 時間: 2025-3-25 03:43
Oncogenes in Chronic Myelogenous LeukemiaThe four previous articles in this series reviewed prinicples of modern molecular biology in the context of hematologic disorders. In this final review, we consider recent insights into the molecular basis of chronic myelogenous leukemia (CML) resulting from the use of these technics.作者: 故意 時間: 2025-3-25 11:23
Experimental Hematology Todayhttp://image.papertrans.cn/e/image/318841.jpg作者: 悄悄移動 時間: 2025-3-25 15:05
Springer Science+Business Media New York 1986作者: 運動的我 時間: 2025-3-25 16:52
Experimental Hematology Today—1985978-1-4612-4920-7Series ISSN 0172-6803 作者: cruise 時間: 2025-3-25 20:19 作者: PRISE 時間: 2025-3-26 01:56
Genetik und psychologische Praxiss unable to support growth and recolonization of cell lines derived from individual Type I colonies. The fact that each factor seems to support the formation of a different type of colony implies that each acts either on different CFU-TL or on CFU-TL at different stages of maturation.作者: 小步走路 時間: 2025-3-26 04:41 作者: OREX 時間: 2025-3-26 11:58 作者: Albinism 時間: 2025-3-26 16:20 作者: 捐助 時間: 2025-3-26 20:41 作者: RODE 時間: 2025-3-27 00:37 作者: otic-capsule 時間: 2025-3-27 04:30
Glycosphingolipids as Specific Differentiation-Markers and Differentiation-Inducers for Human Myeloghis phenomenon gives profound therapeutic importance as well as one of the basic experimental models, providing a clue for elucidating the fundamental mechanisms of regulation for growth and differentiation of hematopoietic cells.作者: 細絲 時間: 2025-3-27 06:04
Immunoglobulin and T-Cell Receptor Gene Rearrangements in Human Acute Leukemiase overcome by utilizing the DNA rearrangement of immunoglobulin (Ig) and T cell receptor genes to reveal the clonality, cellular lineage, and stage of differentiation of such acute undifferentiated leukemias (AUL) (2).作者: etidronate 時間: 2025-3-27 09:47 作者: GLARE 時間: 2025-3-27 16:01
https://doi.org/10.1007/978-3-642-71505-1ctivity [3]. We report here results of studies designed to identify a method of concentrating human serum without loss of its biologically active Ep content, and when unsuccessful in this endeavour, studies were initiated to determine why Ep activity is invariably lost after concentrating human sera.作者: 下垂 時間: 2025-3-27 21:08 作者: 進步 時間: 2025-3-27 23:06
https://doi.org/10.1007/978-3-658-30690-8believed to be targets of acute GVHD. Despite considerable data in animal models and in humans, the precise role of other effector mechanisms such as humoral immunity, antibody-dependent cellular cytotoxicity, natural killer cells, lymphokines, and the monocyte-macrophage system, remain controversial.作者: Hiatus 時間: 2025-3-28 02:26
https://doi.org/10.1007/978-3-662-58643-3ial Seattle experience with autologous marrow transplantation as treatment for patients with relapsed or resistant malignant lymphoma and compares this approach with our previously published experience using syngeneic and allogeneic transplantation in a similar group of patients (3–5).作者: 討厭 時間: 2025-3-28 07:24
Dependence of CFU-S Proliferation on the CFU-S Populationd differentiation resulted in migration of CFU-S from the marrow to spleen (13) and in both organs their proliferation was inversely proportional to their concentration. These local variations in proliferative activity of the CFU-S population suggest that there is local control over CFU-S proliferation.作者: 小步舞 時間: 2025-3-28 13:15 作者: 侵略主義 時間: 2025-3-28 17:49 作者: 細胞 時間: 2025-3-28 18:46
Risk Factors for Acute Graft-vs-Host Disease in Humansbelieved to be targets of acute GVHD. Despite considerable data in animal models and in humans, the precise role of other effector mechanisms such as humoral immunity, antibody-dependent cellular cytotoxicity, natural killer cells, lymphokines, and the monocyte-macrophage system, remain controversial.作者: critic 時間: 2025-3-28 23:37
Autologous Marrow Transplantation for Malignant Lymphomaial Seattle experience with autologous marrow transplantation as treatment for patients with relapsed or resistant malignant lymphoma and compares this approach with our previously published experience using syngeneic and allogeneic transplantation in a similar group of patients (3–5).作者: angiography 時間: 2025-3-29 03:22
Role of T-Lymphocyte Colony Enhancing Factor, TLCEF, in the Induction of CFU-TLtinin (PHA). Using a preparation of partially purified TLCEF, which was devoid of other interleukin activities, it was possible to demonstrate that TLCEF was responsible for the enhancement of Type I colony formation in two-step cultures. On the other hand, interleukin-2 (IL-2), and not TLCEF, was s作者: Intractable 時間: 2025-3-29 07:57 作者: 不近人情 時間: 2025-3-29 11:46
Early Biochemical Steps in Colony Stimulating Factor (CSF) Generation are Induced by Synergy betweenhate (InsP3). DAG activates protein kinase C (PK-C) and InsP3 mobilizes intracellular calcium. Both tumor promoting phorbol esters (TPA) which activate PK-C directly and calcium ionophores which mobilize intracellular calcium bypass inositol phospholipid breakdown. We recently reported that the inte作者: Outmoded 時間: 2025-3-29 19:18
Dependence of CFU-S Proliferation on the CFU-S Populationifferent regions of haemopoietic tissue. In the leg shielding experiments, cellularity, spleen colony-forming unit (CFU-S) content and proliferative activity return to normal in the shielded limb long before they do in the rest of the animal. (5). Following phenylhydrazine (PHZ), demand for erythroi作者: coddle 時間: 2025-3-29 21:45 作者: 傀儡 時間: 2025-3-30 01:24
In Vivo Effects of Urinary Extracts of Patients with Aplastic Anemia on Rat Platelet Production and s after administration of urinary extracts from patients with aplastic anemia (AA). Single intraperitoneal injections of 140 μg and 30 μg of protein (65–90% ethanol precipitate of crude urinary preparation) were administered to Sprague-Dawley rats and BDF. mice, respectively. Circulating platelet co作者: 極力證明 時間: 2025-3-30 04:51 作者: PACT 時間: 2025-3-30 11:40
Establishment of Bone Marrow Stromal Cell Cultures and Permanent Clonal Stromal Cell Lines from Osteutant. The etiology has been presumed due to a defect in the ability the marrow stem cells to differentiate into normally functioning osteoclasts. Data are not available to prove that replacing only the osteoclast precursor (an unidentified cell) will cure the disorder. To test whether marrow stroma作者: troponins 時間: 2025-3-30 14:37
Monoclonal Antibodies Identify Specific Determinants on Reticular Cells in Murine Embryonic and Adulonstrated by the presence of collagen types I and III and fibronectin, and the absence of collagen type IV and laminin. Three antibodies to these fibroblastoid cells exclusively recognized hemopoietic stromal cells in splenic red pulp and bone marrow of adult mice, with the exception of the occasion作者: 巫婆 時間: 2025-3-30 19:58
Stromal Cell Lines from Mouse Bone Marrow: A Model System for the Study of the Hemopoietic Microenvif the stromal tissue which controls hemopoiesis (1–7). It has been, however, impossible to determine conclusively which of the stromal cell types comprising this complex microenvironment tissue is mediating the observed functions. The requirement for pure cell populations for any further experimenta作者: ADAGE 時間: 2025-3-31 00:40 作者: 冒號 時間: 2025-3-31 03:20 作者: 充滿裝飾 時間: 2025-3-31 06:16
Interactions of Differentiation Inducing Agents In Vitro Provide Insight into Molecular Mechanisms ote the therapeutic potential of these agents, little is known about their mechanisms of action. Agents enhancing differentiation to the neutrophil-granulocyte lineage include retinoids, polar-planar compounds such as dimethylsulphoxide (DMSO) and N-methylformamide (N-MF), DNA synthesis inhibitors (D作者: Madrigal 時間: 2025-3-31 09:58 作者: 音樂學者 時間: 2025-3-31 16:04 作者: Coordinate 時間: 2025-3-31 19:45
Response to an Active Vitamin D3 Metabolite of Transplantable Human Myeloid Leukemic Cell Lines in Aula except KG-1 consistently grew nonmet-astatic subcutaneous (sc) tumors after 3 weeks. Cytologic, immuno- and enzyme-cytochemical tests proved identity of respective tumor and cultured cells. Adenosine triphosphatase (ATPase) reactivity was limited to tumorigenie cells in vivo, while leucine amino作者: carbohydrate 時間: 2025-4-1 00:53
Risk Factors for Acute Graft-vs-Host Disease in Humansory cause of death in 15–40% in most series. GVHD is believed to be caused by donor T-lymphocytes that recognize and react against disparate antigens on host tissues. When donors and recipients are identical at the major histocompatability complex, minor histocompatability or other alloantigens are 作者: maverick 時間: 2025-4-1 04:12
Autologous Marrow Transplantation for Malignant Lymphomaerapy delivered at conventional doses. Based on the success of high dose chemoradiotherapy and marrow transplantation as treatment for relapsed leukemia, a number of studies have been performed using a similar approach in patients with relapsed malignant lymphoma (1–14). This report details the init作者: ASSET 時間: 2025-4-1 06:18 作者: 拉開這車床 時間: 2025-4-1 11:34 作者: Pituitary-Gland 時間: 2025-4-1 15:36
In Vivo Effects of Urinary Extracts of Patients with Aplastic Anemia on Rat Platelet Production and increase significantly 24 h post-injection, peaked by 48 h, and returned to normal levels after 96 h..A significant increase in the number of solitary megakaryocytes was observed 48 h post-injection, with the maximum number occuring after 72 h, remaining at this relatively high level for up to 96 h 作者: 斷言 時間: 2025-4-1 19:26