標(biāo)題: Titlebook: Excitatory Amino Acids; Peter J. Roberts,Jon Storm-Mathisen,Harry F. Bradf Book 1986 The Editors and the Contributors 1986 amino acid.huma [打印本頁(yè)] 作者: 貪污 時(shí)間: 2025-3-21 20:04
書(shū)目名稱(chēng)Excitatory Amino Acids影響因子(影響力)
作者: membrane 時(shí)間: 2025-3-21 22:23 作者: Phenothiazines 時(shí)間: 2025-3-22 02:40
Metabolic Precursors of the Transmitter Pools of Glutamate and Aspartate, pools of glutamate, aspartate and GABA. Evidence supporting the concept that a-ketoglutarate and malate are supplied by astrocytes to synaptic terminals include the immunohistochemical and biochemical demonstration that pyruvate carboxylase, the principal anaplerotic enzyme in CNS tissues, is locat作者: Overdose 時(shí)間: 2025-3-22 05:37
,Glia–Neuronal Interrelationships in the Metabolism of Excitatory Amino Acids,gh capacity transporter. In addition, glutamine synthesis and catabolism are intimately associated with neurotransmitter glutamate. The enzyme, glutamine synthetase, is highly enriched in astrocytes. The catabolic enzyme, glutaminase, may or may not be enriched in glutamergic nerve endings. Experime作者: ablate 時(shí)間: 2025-3-22 10:35
The Compartmentation and Turnover of Glutamate and GABA: A Better Understanding by the Use of Drugse and GABA can be explained from a two-compartment model. (Berl et al, 1961; Berl and Clarke, 1978; van den Berg and Garfinkel, 1971; Balazs et al, 1970). Such a simple classification is surprising in view of the heterogenous composition of the brain both in anatomical and biochemical terms. The two作者: BRUNT 時(shí)間: 2025-3-22 13:45
Immunocytochemical Localization of Enzymes Involved in the Metabolism of Excitatory Amino Acids,mino acids. Glutaminase is found to be enriched in several putative excitatory amino acid neurons including the auditory nerve, neurons of the hippocampus and cerebral cortex and granule cells of the cerebellum. Cytoplasmic aspartate aminotransferase is enriched in some excitatory amino acid neurons作者: BRUNT 時(shí)間: 2025-3-22 17:35 作者: 浪費(fèi)物質(zhì) 時(shí)間: 2025-3-23 00:35
Excitatory Amino Acids as Transmitters in the Olfactory System,some olfactory cortical pyramidal cells is reviewed. Several reports describing the synaptically-evoked release of endogenous Asp and/or Glu from olfactory cortex slices support such a role. Surgical and chemical lesions cause loss of Asp and/or Glu at sites corresponding to the location of the cand作者: Proponent 時(shí)間: 2025-3-23 02:56 作者: CAPE 時(shí)間: 2025-3-23 07:41 作者: debris 時(shí)間: 2025-3-23 11:40
Glutamate Transport in the Synaptic Vesicle,naptic vesicles in an ATP-dependent but Na+-independent manner. Pharmacological evidence suggests that the vesicular glutamate uptake is driven by an electrochemical proton gradient generated by a proton-pump ATPase. The ATP-dependent vesicular uptake is highly specific for glutamate, and the glutam作者: PARA 時(shí)間: 2025-3-23 16:37
Presynaptic Receptors for Excitatory Amino Acid Transmitters,l nervous system, and this has led to the characterisation of at least three subtypes (viz. those activated by N-methyl-Daspartate (NMDA), quisqualate and kainate) on the basis of electrophysiological studies (see Watkins, this volume). In contrast to the postsynaptic receptors, relatively little at作者: 針葉 時(shí)間: 2025-3-23 19:53 作者: intertwine 時(shí)間: 2025-3-24 01:21 作者: 窗簾等 時(shí)間: 2025-3-24 02:32 作者: Bernstein-test 時(shí)間: 2025-3-24 10:00 作者: Emasculate 時(shí)間: 2025-3-24 12:49 作者: 無(wú)節(jié)奏 時(shí)間: 2025-3-24 18:06
Anatomical Organization of NMDA, Kainate and Quisqualate Receptors,he CNS. Autoradiography allows a quantitative description of anatomical and pharmacological properties of binding sites in specific CNS locations which can then be correlated to function. Receptors in a single dendritic field can be both biochemically characterized and rigorously studied by electrop作者: 有組織 時(shí)間: 2025-3-24 20:23 作者: Apoptosis 時(shí)間: 2025-3-25 00:37 作者: 最高點(diǎn) 時(shí)間: 2025-3-25 03:19 作者: spinal-stenosis 時(shí)間: 2025-3-25 10:41
https://doi.org/10.1007/978-3-319-63664-1gh capacity transporter. In addition, glutamine synthesis and catabolism are intimately associated with neurotransmitter glutamate. The enzyme, glutamine synthetase, is highly enriched in astrocytes. The catabolic enzyme, glutaminase, may or may not be enriched in glutamergic nerve endings. Experime作者: 影響帶來(lái) 時(shí)間: 2025-3-25 15:12
https://doi.org/10.1007/978-3-658-29144-0e and GABA can be explained from a two-compartment model. (Berl et al, 1961; Berl and Clarke, 1978; van den Berg and Garfinkel, 1971; Balazs et al, 1970). Such a simple classification is surprising in view of the heterogenous composition of the brain both in anatomical and biochemical terms. The two作者: 觀(guān)察 時(shí)間: 2025-3-25 16:14
A Review of the Relevant Literature,mino acids. Glutaminase is found to be enriched in several putative excitatory amino acid neurons including the auditory nerve, neurons of the hippocampus and cerebral cortex and granule cells of the cerebellum. Cytoplasmic aspartate aminotransferase is enriched in some excitatory amino acid neurons作者: Exclaim 時(shí)間: 2025-3-25 22:53
The Power of Formative Assessment,e antisera reacted selectively with brain protein-glutarai dehyde conjugates of Glu or Asp, as assessed in a model system that permitted testing under conditions closely similar to those of the immunocytochemical procedure. Specific staining was abolished after solid phase adsorption with fixation c作者: Oration 時(shí)間: 2025-3-26 02:20 作者: cauda-equina 時(shí)間: 2025-3-26 06:08 作者: 案發(fā)地點(diǎn) 時(shí)間: 2025-3-26 11:00 作者: 爭(zhēng)論 時(shí)間: 2025-3-26 14:37 作者: 人類(lèi)的發(fā)源 時(shí)間: 2025-3-26 18:25
Formatives Assessment in der Grundschulel nervous system, and this has led to the characterisation of at least three subtypes (viz. those activated by N-methyl-Daspartate (NMDA), quisqualate and kainate) on the basis of electrophysiological studies (see Watkins, this volume). In contrast to the postsynaptic receptors, relatively little at作者: Encoding 時(shí)間: 2025-3-26 22:41 作者: 小丑 時(shí)間: 2025-3-27 04:15
Funktion, Abbildung, Farbe, Raum,rones (Curtis et al., 1960), and subsequent studies which first showed the more powerful and often more prolonged actions of many other natural and non-natural compounds possessing the same general pattern of functional groups were also conducted in this tissue (Curtis and Watkins, 1960, 1963; Bisco作者: progestogen 時(shí)間: 2025-3-27 07:23
,Formelle Gesetze im r?mischen Rechte,nan, 1983). Much of this classification has been derived from experiments on isolated CNS preparations, in particular the amphibian spinal cord in vitro. This preparation was first described nearly a quarter of a century ago as a very useful model system to screen the basic pharmacological propertie作者: interpose 時(shí)間: 2025-3-27 13:15 作者: 無(wú)法解釋 時(shí)間: 2025-3-27 15:45
https://doi.org/10.1007/978-3-658-33690-5mpts to exploit these techniques to label receptors for the excitatory amino acids were reported in 1974 by Roberts and by Michaelis and his coworkers. Using synaptic membrane fractions isolated from the rat brain, these authors demonstrated the presence of a population(s) of L-[14C]glutamate bindin作者: Decibel 時(shí)間: 2025-3-27 18:25
https://doi.org/10.1007/978-3-662-32995-5he CNS. Autoradiography allows a quantitative description of anatomical and pharmacological properties of binding sites in specific CNS locations which can then be correlated to function. Receptors in a single dendritic field can be both biochemically characterized and rigorously studied by electrop作者: Radiation 時(shí)間: 2025-3-28 01:44 作者: 惹人反感 時(shí)間: 2025-3-28 02:46
Identification of Pathways for Acidic Amino Acid Transmitters and Search for New Candidates: SulphuIn this paper, the emphasis will be given on two topics: (I) The information which can be drawn from selective retrograde labeling of CNS pathways while using D-[3H]-?SP as a marker. (II) The search for new neuroac-tive substances, possibly involved in neurotransmission.作者: 撕裂皮肉 時(shí)間: 2025-3-28 06:54 作者: 才能 時(shí)間: 2025-3-28 13:05
The Editors and the Contributors 1986作者: BABY 時(shí)間: 2025-3-28 15:40
Overview: 978-1-349-08479-1作者: 賠償 時(shí)間: 2025-3-28 21:59 作者: Gum-Disease 時(shí)間: 2025-3-28 23:21 作者: 簡(jiǎn)潔 時(shí)間: 2025-3-29 03:05 作者: 聽(tīng)寫(xiě) 時(shí)間: 2025-3-29 08:34 作者: Flustered 時(shí)間: 2025-3-29 12:06
Antibodies for the Localization of Excitatory Amino Acids,a nerve terminal pool was selectively labelled in hippocampal slices fixed by immersion after incubation in Krebs1 medium. This pool could be depleted Ca2+-dependently under depolarizing conditions, with a concomitant accumulation of immunoreactivity in glia. The findings give proof for the existenc作者: 誘使 時(shí)間: 2025-3-29 18:52 作者: 粘 時(shí)間: 2025-3-29 19:42 作者: 冰河期 時(shí)間: 2025-3-30 02:50
Effects of Kainic Acid on Different Populations of Cerebellar Interneurones and Astrocytes Culturednput (Mc Lennan, 1980). More recently, kainate has been shown to affect neurotransmitter release and uptake in different tissue preparations of several brain areas. For example, the excitotoxin caused glutamate and aspartate release from brain synaptosomes (Pastuszko et al., 1984), cerebellar, hippo作者: 大暴雨 時(shí)間: 2025-3-30 04:57 作者: 充滿(mǎn)裝飾 時(shí)間: 2025-3-30 08:55
Pharmacology of Excitatory Amino Acids on Spinal Cord Neurones,tinuous super-fusion of test substances. In this report we describe how the effects of excitatory amino acids on frog spinal neurones were characterized in terms of neuronal specificity, ionic dependence and receptor classification.作者: 允許 時(shí)間: 2025-3-30 14:29
L-Glutamic Acid Receptors on Locust Muscle: Pharmacological Properties and Single Receptor Channel is considered by some to be the main neurotransmitter receptor for L-glutamic acid in the CNS. The pharmacology of glutamatergic systems in arthropods is also complicated and there are differences between species (Usherwood, 1978; Nistri & Constanti, 1979; Piek, 1985).作者: 信徒 時(shí)間: 2025-3-30 17:55 作者: 殺蟲(chóng)劑 時(shí)間: 2025-3-30 21:53
https://doi.org/10.1007/978-3-658-29144-0tio exceeds 1.0 a short time after injection. In the case of glucose, pyruvate, lactate, glycerol and hydroxybutyrate the ratio stays well below 1.0. The results can be explained if the first group of precursors are either preferentially taken up or metabolized in a small pool of glutamate which are作者: 未開(kāi)化 時(shí)間: 2025-3-31 04:00 作者: infatuation 時(shí)間: 2025-3-31 07:25
Die Anwendung des formativen Messmodells,qualate and NMDA receptors. Some receptor agonists exhibit a ‘response desensitization’ and there is the possibility that an as yet unknown category of receptors may contribute to responses evoked by exogenous Asp and Glu.作者: 解凍 時(shí)間: 2025-3-31 09:52
Art in Republics: Venice and the Netherlandse characteristics as in the native vesicles. The GABA transporter has been purified to near homogeneity using transport activity upon reconstitution as an assay. Purification steps included fractionation of the cholate extract with ammonium sulfate, DEAE cellulose and lectin-chromatography. It appea作者: 遣返回國(guó) 時(shí)間: 2025-3-31 14:09 作者: 充氣女 時(shí)間: 2025-3-31 17:43
Funktion, Abbildung, Farbe, Raum, acid antagonist described, L-glutamate diethylester (GDEE), could be used to rank the excitants in order of their susceptibility to blockade, that D-a -aminoadipate (DAA) blocked actions which were resistant to GDEE, and that the effects produced by a few compounds were relatively unaffected by eit