作者: custody 時(shí)間: 2025-3-21 21:02
Book 1984mo- lecular techniques, can now study with great precision the structure and regulation of specific genes. As a discipline, molecular biology is no longer a mere subspeciality of biology or biochemistry: it is the new biology. Current approaches to the outstanding problems in virtually all the tradi作者: Conclave 時(shí)間: 2025-3-22 03:10
Pattern of Histone-Variant Synthesis and Implications for Gene Regulation,he DNA in the cell nucleus (Felsenfeld, 1978). Thus, histones may affect gene expression by changing the structure of chromatin. However, the many complex and multiple posttranslational modifications of histones suggest that they have other roles in addition to purely structural ones.作者: 表示問 時(shí)間: 2025-3-22 07:23
Human and Mouse Globin-Gene Sequences Introduced into Mice by Microinjection of Fertilized Mouse Egus CCAAT and TATA blocks 5′ to coding sequences) have been identified as important for influencing the rate and accuracy of transcript initiation (Efstratiadis .., 1980; Lauer .., 1980; Dierks .., 1981; Mellon .., 1981; Grosveld .., 1982).作者: Obedient 時(shí)間: 2025-3-22 10:24 作者: Onerous 時(shí)間: 2025-3-22 15:42
Ti Plasmids as Gene Vectors for Plants,gn genes into the plant nucleus, but also contains a set of genes that regulate plant-cell development and differentiation. As a result of this gene transfer, crown gall cells, unlike untransformed plant tissues, can be cultured under axenic conditions on synthetic media in the absence of growth hormones, i.e., cytokinins and auxins.作者: Onerous 時(shí)間: 2025-3-22 18:52
Zur Struktur des platonischen Dialogs,unit contains a 5 S rRNA and the 23 S rRNA combined with 31 proteins. Eukaryotic 80 S ribosomes are appreciably larger. Their small 40 S subunit is comprised of 18 S rRNA and approximately 30 proteins, while the large 60 S subunit is much more complex, with one molecule each of 5 S, 5.8 S, and 28 S rRNA and 45–50 proteins.作者: OTTER 時(shí)間: 2025-3-22 23:10 作者: Ventricle 時(shí)間: 2025-3-23 02:38
https://doi.org/10.1007/978-3-658-15325-0he DNA in the cell nucleus (Felsenfeld, 1978). Thus, histones may affect gene expression by changing the structure of chromatin. However, the many complex and multiple posttranslational modifications of histones suggest that they have other roles in addition to purely structural ones.作者: Colonnade 時(shí)間: 2025-3-23 08:41 作者: Myosin 時(shí)間: 2025-3-23 09:48
Fallbeispiel Energiewende in der Eifel,. transcription systems may respond to different regulatory signals and thus do not afford the ideal system for the study of . transcriptional control (Benoist and Chambon, 1980). The study of promoters after introduction into tissue-culture cells is crucial.作者: 他姓手中拿著 時(shí)間: 2025-3-23 15:30
,Auswertung der Interviews und Frageb?gen,gn genes into the plant nucleus, but also contains a set of genes that regulate plant-cell development and differentiation. As a result of this gene transfer, crown gall cells, unlike untransformed plant tissues, can be cultured under axenic conditions on synthetic media in the absence of growth hormones, i.e., cytokinins and auxins.作者: GEN 時(shí)間: 2025-3-23 18:25
Dialgebra (co)homology with coefficients,c development. Thus, the genetic events responsible for processes such as organ determination and tissue differentiation are difficult if not impossible to examine. Our laboratory has sought to overcome this problem by developing a gene-transfer system for the intact organism. We have chosen the mouse as a model system.作者: 低能兒 時(shí)間: 2025-3-24 00:59
The Production of Transgenic Mice,c development. Thus, the genetic events responsible for processes such as organ determination and tissue differentiation are difficult if not impossible to examine. Our laboratory has sought to overcome this problem by developing a gene-transfer system for the intact organism. We have chosen the mouse as a model system.作者: 華而不實(shí) 時(shí)間: 2025-3-24 06:09 作者: 刻苦讀書 時(shí)間: 2025-3-24 06:42 作者: Diverticulitis 時(shí)間: 2025-3-24 12:17 作者: hematuria 時(shí)間: 2025-3-24 18:34 作者: spinal-stenosis 時(shí)間: 2025-3-24 22:00
Cloning and Structure Analysis of Histocompatibility Class I and Class II Genes,teins and serum proteins known as histocompatibility antigens (Klein, 1975). Through these antigens, the cells of the immune system interact and thus regulate the antibody and cellular immune response to foreign antigens (Zinkernagel and Doherty, 1974; Klein, 1979). Biochemically, these antigens hav作者: 走調(diào) 時(shí)間: 2025-3-25 02:23 作者: ineffectual 時(shí)間: 2025-3-25 05:43
Human and Mouse Globin-Gene Sequences Introduced into Mice by Microinjection of Fertilized Mouse Egviewed in Stamatoyannopoulos and Nienhuis, 1981). From sequence data and functional analysis of cloned globin genes, some regions (such as the consensus CCAAT and TATA blocks 5′ to coding sequences) have been identified as important for influencing the rate and accuracy of transcript initiation (Efs作者: bile648 時(shí)間: 2025-3-25 11:31 作者: 易發(fā)怒 時(shí)間: 2025-3-25 12:43 作者: LASH 時(shí)間: 2025-3-25 18:43 作者: GUILE 時(shí)間: 2025-3-25 23:56 作者: NATTY 時(shí)間: 2025-3-26 02:06 作者: CANT 時(shí)間: 2025-3-26 05:00
Dialektik und Dialektikf?higkeit that differential protein packaging of coding sequences at the broad level of the chromomere, or in the specific vicinity of a gene, or both, might be an important determinant in the selective expression of these sequences. Our goals have been to map features of chromatin structure relative to know作者: 難解 時(shí)間: 2025-3-26 12:21
,Beschreibung des Führungsansatzes,e and 5-methylcytosine (m.C) are found, while in mammalian DNA, the only detectable methylated base is m.C (Wyatt, 1951). From 2 to 7% of cytosine residues are found as m.C, and more than 90% of the methylated C residues are found in the dinucleotide sequence CpG (Grippo .., 1970). The distribution 作者: Projection 時(shí)間: 2025-3-26 16:00
https://doi.org/10.1007/978-3-658-15325-0n of chromatin and (2) the regulation of histone gene expression. It is generally accepted that histones serve a structural role in the packaging of the DNA in the cell nucleus (Felsenfeld, 1978). Thus, histones may affect gene expression by changing the structure of chromatin. However, the many com作者: 輕浮思想 時(shí)間: 2025-3-26 19:37 作者: 節(jié)省 時(shí)間: 2025-3-27 00:32 作者: oxidant 時(shí)間: 2025-3-27 03:33
Dialgebra (co)homology with coefficients,es can then be employed in gene-transfer experiments to study the regulation of gene expression. Such gene-transfer experiments using mammalian somatic cells in culture as recipients have produced a significant body of data relating to the control of gene function (Scangos and Ruddle, 1981). This ex作者: NUDGE 時(shí)間: 2025-3-27 08:49
Cristina Barés Gómez,Matthieu Fontaineviewed in Stamatoyannopoulos and Nienhuis, 1981). From sequence data and functional analysis of cloned globin genes, some regions (such as the consensus CCAAT and TATA blocks 5′ to coding sequences) have been identified as important for influencing the rate and accuracy of transcript initiation (Efs作者: Constrain 時(shí)間: 2025-3-27 10:39
Fallbeispiel Energiewende in der Eifel,se sequences. The . transcription systems developed by Manley .. (1980) and Weil .. (1979) offer one approach. However, it is becoming clear that the . transcription systems may respond to different regulatory signals and thus do not afford the ideal system for the study of . transcriptional control作者: 小畫像 時(shí)間: 2025-3-27 15:05
,Auswertung der Interviews und Frageb?gen,s of a set of genes that regulate cell and organ development. In other words, in nature, a mechanism exists that not only efficiently introduces foreign genes into the plant nucleus, but also contains a set of genes that regulate plant-cell development and differentiation. As a result of this gene t作者: 排出 時(shí)間: 2025-3-27 18:56 作者: 震驚 時(shí)間: 2025-3-27 22:44
,Fallbeispiel: ?Ich muss etwas erreichen!“,ional level, apparently largely at the initiation step. Consequently, much interest is being devoted to analyzing the transcriptional process, both . and .. Studies in manipulable systems, especially those that utilize cloned DNA templates, are proving most fruitful. Systems in which RNA polymerase 作者: FLAX 時(shí)間: 2025-3-28 03:19
Zur Struktur des platonischen Dialogs,, is to elucidate the architecture and eventually the function of these multi-molecular complexes. Prokaryotic 70 S ribosomes can be dissociated into a small 30 S subunit and a large 50 S subunit. The 30 S subunit contains 16 S ribosomal RNA (rRNA) in association with 21 proteins, while the 50 S sub作者: grovel 時(shí)間: 2025-3-28 08:07
Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposiahttp://image.papertrans.cn/e/image/316447.jpg作者: 動(dòng)物 時(shí)間: 2025-3-28 11:59 作者: BLANK 時(shí)間: 2025-3-28 15:50
978-1-4684-7461-9Plenum Press, New York 1984作者: Flavouring 時(shí)間: 2025-3-28 19:04 作者: 無目標(biāo) 時(shí)間: 2025-3-29 00:59
,Beschreibung des Führungsansatzes,1982). The symmetry of the CpG sequence allows one parental strand, which is methylated, to act as a template for the methylation of the new strand (Holliday and Pugh, 1975; Razin and Riggs, 1980; Ehrlich and Wang, 1981).作者: Negligible 時(shí)間: 2025-3-29 04:29
Christa Bhatt,Claudia Maria Schmidtrmined for the thymidine kinase gene of herpes simplex virus (McKnight and Kingsbury, 1982). In this gene, mutations in a guanine-rich segment between bases ?7 and ?61 and a cytosine-rich segment between bases ?80 and ?105 markedly decrease the efficiency of transcription. Although the ?61 to ?80 re作者: Parley 時(shí)間: 2025-3-29 09:07
https://doi.org/10.1007/978-3-030-30221-4ns are that they are highly polymorphic within the population. At least 35 alleles are known at the . locus, 20 at the . locus, and fewer than 10 at the . locus. In the mouse, the extent of polymorphism at the class I loci is even higher; i.e., close to 100 alleles at both the . and -. loci. In cont作者: CRATE 時(shí)間: 2025-3-29 13:14 作者: 鞠躬 時(shí)間: 2025-3-29 17:38
,Fallbeispiel: ?Ich muss etwas erreichen!“, with these systems, many aspects of the nucleoprotein interactions that direct eukaryotic transcription—that is, the nucleotide sequences and the protein species that facilitate and regulate this process—are being elucidated (Sakonju .,1980; Bogenhagen .,1980; Grosschedl and Birnsteil, 1980b; Fowlk作者: NORM 時(shí)間: 2025-3-29 21:57 作者: 錫箔紙 時(shí)間: 2025-3-30 02:08
implications of recent dis- coveries, often before the scientific community has had the opportunity to fully scrutinize the developments. Since many of the recent findings in this field have practical implications, quite often the symposia in molecular biology are sponsored by private industry and are of spec978-1-4684-7461-9978-1-4684-7459-6作者: 一罵死割除 時(shí)間: 2025-3-30 07:27
Some Observations on DNA Structure and Chromatin Organization at Specific Loci in , ,staining of polytene chromosomes have identified several presumptive structural nonhistone chromosomal proteins, including some the distribution pattern of which indicates a preferential association with loci that are to be expressed at some point in the development of the salivary gland cells of ..