作者: 我就不公正 時(shí)間: 2025-3-22 00:15 作者: 爆米花 時(shí)間: 2025-3-22 03:01 作者: 克制 時(shí)間: 2025-3-22 04:48
Actions of Calcium Agonists and Antagonists on Femoral Arteries of Spontaneously Hypertensive Ratsthe data compared with findings in normotensive Wistar-Kyoto rats (WKY). The addition of Bay k 8644 produced a dose-dependent contraction in the SHR femoral artery with a pD. value of 8.55. The maximum contraction induced by this Ca. agonist (1 x 10–..) was comparable with the maximum developed by e作者: 實(shí)現(xiàn) 時(shí)間: 2025-3-22 08:46
Altered Vascular Calcium Metabolism As a Possible Cause of Increased Blood Pressure in Essential Hyphere is little information from human studies as to whether such abnormalities play a role in the development of hypertension, but from rat studies the available evidence does not support a direct connection between EC coupling abnormalities and increased blood pressure, although the possibility can作者: Nefarious 時(shí)間: 2025-3-22 15:56
Calcium-Membrane Interactions in Smooth Muscle in Relation to Hypertensionractionation technique with special reference to the relationship between the alterations of calcium ion handling in vascular smooth muscle and the pathogenesis of spontaneous hypertension in rats. The calcium-membrane interactions include ATP-dependent Ca-transport, Na-dependent Ca-transport (Na-Ca作者: Nefarious 時(shí)間: 2025-3-22 17:37 作者: peritonitis 時(shí)間: 2025-3-22 23:40 作者: 我要威脅 時(shí)間: 2025-3-23 03:33
Growth Factors and Vascular Smooth Muscle Cells in Spontaneously Hypertensive Ratsth increased synthesis of collagen and noncollagen protein. Cultured VSMCs from rat aorta appear to be a suitable in vitro system to study the mechanism of cellular proliferation of VSMC, because they are completely free from mechanical and neurohumoral influence. Therefore, the present study was de作者: FOIL 時(shí)間: 2025-3-23 06:34
Calcium and Calcium Antagonists on Vascular Damage in Spontaneously and Dahl Hypertensive Rats of transmembrane calcium influx by nifedipine prevented the genetically determined hypertension, cardiac hypertrophy, and renal ischaemia in Aoki spontaneously hypertensive rats. In salt-sensitive Dahl rats, nifedipine and its calcium antagonistic dihydropyridine derivatives prevented vascular fibr作者: 協(xié)議 時(shí)間: 2025-3-23 10:11
Use of Isolated Membranes of Smooth Muscle to Study Calcium Channelsrmore, other studies show that binding of these antagonists correlates with their functional effects in the same tissue. However, the agents have no effect detected to date on Ca fluxes into or out of isolated vesicles from the same tissue. Thus, it is possible that Ca. channels are inactivated duri作者: contradict 時(shí)間: 2025-3-23 16:29
Therapeutic Role of Calcium Antagonists in Essential Hypertensionessential hypertension..A major, and as yet unresolved, question is whether a disturbance of calcium transport mechanisms in vascular smooth muscle represents a fundamental fault in essential hypertension. To demonstrate that this is the case, disturbances of calcium transport and an associated vasc作者: quiet-sleep 時(shí)間: 2025-3-23 19:22
Effects of Calcium Antagonists in Essential Hypertension with Special Reference to Renal Functionf the untreated blood pressure and the severity of the disease seem to be major determinants. Regional vascular resistance, age, renin status, and plasma concentrations obtained appear to be factors of limited value in this respect..In studies on renal function, nifedipine has been found to have sig作者: 憤怒歷史 時(shí)間: 2025-3-23 23:09
Dihydropyridines As Antihypertensive Agents intracellular stores. Calcium entry blockers selectively and reversibly reduce the influx of Ca. into the cell through the cell membrane and from bound sites within the cell. The ability of Ca. channel blockers to relax vascular smooth muscle and, therefore, to decrease peripheral vascular resistan作者: evanescent 時(shí)間: 2025-3-24 04:03
Altered Vascular Calcium Metabolism As a Possible Cause of Increased Blood Pressure in Essential Hypnot be excluded that the increased sensitivity is a substrate upon which other factors may act. Further work is required, particularly using human isolated vascular preparations, to delineate more precisely the role of vascular abnormalities in the pathogenesis of essential hypertension.作者: 大氣層 時(shí)間: 2025-3-24 07:43 作者: 和音 時(shí)間: 2025-3-24 11:32
Book 1986ctober 23 and 24, 1985 in Nagoya, Japan. The meeting was an official satellite symposium to the meeting of the Fifth International Symposium on Rats with Spon- taneous Hypertension and Related Studies in Kyoto, October 20-22, 1985. The Nagoya symposium was made possible by offi- cial grants from the作者: IRATE 時(shí)間: 2025-3-24 18:35
Applications for Texture and Patterns,fspring. The rats with the highest blood pressure were selected from the offspring and brother-sister inbreeding provided rats with spontaneous hypertension. All the offspring of the third and successive generations developed hypertension. The development and establishment of a strain of SHR were completed by 1963.作者: 生來 時(shí)間: 2025-3-24 20:04
Modeling Sound Propagation in the Ocean,studies using an irreversible ligand of the dihydropyridine type for Ca channels applied to isolated cells found a similar locus of binding to plasma membranes, but binding characteristics were not studied. Thus, the relationship between binding of these antagonists to plasmalemmal sites and their functional effects needs further study.作者: connoisseur 時(shí)間: 2025-3-25 01:16
Discovery of the Spontaneously Hypertensive Ratfspring. The rats with the highest blood pressure were selected from the offspring and brother-sister inbreeding provided rats with spontaneous hypertension. All the offspring of the third and successive generations developed hypertension. The development and establishment of a strain of SHR were completed by 1963.作者: Aggregate 時(shí)間: 2025-3-25 05:20
Use of Isolated Membranes of Smooth Muscle to Study Calcium Channelsstudies using an irreversible ligand of the dihydropyridine type for Ca channels applied to isolated cells found a similar locus of binding to plasma membranes, but binding characteristics were not studied. Thus, the relationship between binding of these antagonists to plasmalemmal sites and their functional effects needs further study.作者: 慟哭 時(shí)間: 2025-3-25 10:37 作者: 危機(jī) 時(shí)間: 2025-3-25 15:18 作者: 恃強(qiáng)凌弱的人 時(shí)間: 2025-3-25 18:07
Conservation Laws for Multiphase Flow,not be excluded that the increased sensitivity is a substrate upon which other factors may act. Further work is required, particularly using human isolated vascular preparations, to delineate more precisely the role of vascular abnormalities in the pathogenesis of essential hypertension.作者: peritonitis 時(shí)間: 2025-3-25 23:05
Etiological Classification of Hypertensione of crossbreedings of the spontaneously hypertensive rat (SHR), which demonstrated that the inheritance of hypertension in the SHR might be the incomplete dominant form transferred by three major genes and not completely polygenic. There are three qualitatively different kinds of hypertension anima作者: LINES 時(shí)間: 2025-3-26 02:33
Actions of Calcium Agonists and Antagonists on Femoral Arteries of Spontaneously Hypertensive Ratswas also observed in the SHR femoral artery. Contractions induced by alpha adrenoceptor stimulation were not different between SHR and WKY. Contractile responses of the SHR femoral artery to Bay k 8644 were antagonized competitively by both nifedipine (pA. = 8.36) and verapamil (pA. = 6.77), but non作者: deface 時(shí)間: 2025-3-26 04:54
Calcium-Membrane Interactions in Smooth Muscle in Relation to Hypertensionelevated blood pressure in hypertension. It also occurs in several forms of experimentally induced hypertension in rats. Such a Ca-transport deficit is present in nonvascular smooth muscles as well in spontaneous hypertension, but not in experimental hypertension. This suggests that the altered ATP-作者: emulsify 時(shí)間: 2025-3-26 12:21
Effects of Diltiazem on Myogenic Tone in Pressurized Brain Arteries from Spontaneously Hypertensive ntaneous tone is similar in resistance-sized cerebral arteries taken from hypertensive and normotensive rats; (2) tone is dependent on the influx of extracellular calcium; and (3) the diltiazem sensitivity of the population of calcium channels responsible for maintaining this tone is not altered in 作者: Ingenuity 時(shí)間: 2025-3-26 13:39 作者: Mortal 時(shí)間: 2025-3-26 20:46
Calcium and Calcium Antagonists on Vascular Damage in Spontaneously and Dahl Hypertensive Ratsts (SHR SP), a high-salt diet resulted in severe lesions with high mortality without any additional increase in blood pressure. Treatment with the calcium antagonistic dihydropyridines nitrendipine or nimodipine markedly increased survival and the reduced vascular lesions without decreasing the high作者: 粗鄙的人 時(shí)間: 2025-3-26 22:37 作者: 壓艙物 時(shí)間: 2025-3-27 04:11
Effects of Calcium Antagonists in Essential Hypertension with Special Reference to Renal Function are caused by nifedipine, the natriuretic effect may be blunted..We propose that in addition to the direct vascular effects nifedipine has a specific proximal tubular effect on sodium reabsorption which may play a role in the long-term blood pressure response. Strong vasodilatory effects may counte作者: AMOR 時(shí)間: 2025-3-27 09:18 作者: 輕率的你 時(shí)間: 2025-3-27 11:21
Book 1986s attracted a great deal of attention in the last two decades. The mode of action of calcium ions was revealed at the molecular level. The hypertension model of the spontaneously hypertensive rat has been widely utilized for research into the fundamental mechanisms of genetic hyperten- sion, stroke,作者: receptors 時(shí)間: 2025-3-27 13:46
muscle has attracted a great deal of attention in the last two decades. The mode of action of calcium ions was revealed at the molecular level. The hypertension model of the spontaneously hypertensive rat has been widely utilized for research into the fundamental mechanisms of genetic hyperten- sion, stroke,978-4-431-68050-5978-4-431-68048-2作者: 敵手 時(shí)間: 2025-3-27 21:30
Pratim Sengupta,Amanda Dickes,Amy Farrise of crossbreedings of the spontaneously hypertensive rat (SHR), which demonstrated that the inheritance of hypertension in the SHR might be the incomplete dominant form transferred by three major genes and not completely polygenic. There are three qualitatively different kinds of hypertension anima作者: 呼吸 時(shí)間: 2025-3-28 00:36 作者: 褲子 時(shí)間: 2025-3-28 04:05 作者: 易于出錯(cuò) 時(shí)間: 2025-3-28 06:27 作者: BABY 時(shí)間: 2025-3-28 11:17 作者: aggressor 時(shí)間: 2025-3-28 17:14 作者: 脫落 時(shí)間: 2025-3-28 21:11 作者: ureter 時(shí)間: 2025-3-28 23:45
https://doi.org/10.1007/978-3-030-48186-5 are caused by nifedipine, the natriuretic effect may be blunted..We propose that in addition to the direct vascular effects nifedipine has a specific proximal tubular effect on sodium reabsorption which may play a role in the long-term blood pressure response. Strong vasodilatory effects may counte作者: DEAF 時(shí)間: 2025-3-29 04:51 作者: 流行 時(shí)間: 2025-3-29 08:11
Actions of Calcium Antagonists on Smooth Muscle Cells of Vascular Tissues作者: 芳香一點(diǎn) 時(shí)間: 2025-3-29 14:57 作者: 矛盾心理 時(shí)間: 2025-3-29 19:17
http://image.papertrans.cn/e/image/315454.jpg作者: Noctambulant 時(shí)間: 2025-3-29 20:44 作者: guardianship 時(shí)間: 2025-3-30 01:37 作者: PLE 時(shí)間: 2025-3-30 05:06 作者: amygdala 時(shí)間: 2025-3-30 11:57
Pratim Sengupta,Amanda Dickes,Amy Farrisrs have questioned the concept, mechanism, and classification of hypertension in humans and animals. Bright reported hypertension as a renal disease. Gull and Sutton distinguished hypertension from renal disease. Albutt, Frank, and others assumed that subjects with essential hypertension differed qu作者: 鑒賞家 時(shí)間: 2025-3-30 13:43
Raghuraman Venkatapathy,Nina Ching Y. Wangrtensive rats (SHR). The stimulating agent used was norepinephrine (NE). The results show clearly that Ca. influx into smooth muscle cells from resistance vessels was much higher in the SHR than in the WKY rats. Potential sensitive Ca. channels (PSC) and receptor-operated Ca. channels (ROC) may poss作者: synovial-joint 時(shí)間: 2025-3-30 18:58 作者: CLAIM 時(shí)間: 2025-3-30 20:53 作者: fabricate 時(shí)間: 2025-3-31 01:23 作者: Definitive 時(shí)間: 2025-3-31 06:01
Severino P. C. Marques,Guillermo J. Creus was potentiated by promotors of influx of Ca such as high K, cardiac glycosides, and BAY k 8644, a 1,4-dihydropyridine Ca agonist, while the potentiated responses were inhibited by Ca antagonists. The significance of myogenic tone of vascular tissues in physiological and pathological conditions is 作者: 雀斑 時(shí)間: 2025-3-31 09:24 作者: 共同生活 時(shí)間: 2025-3-31 14:12
https://doi.org/10.1007/978-3-322-81318-3th increased synthesis of collagen and noncollagen protein. Cultured VSMCs from rat aorta appear to be a suitable in vitro system to study the mechanism of cellular proliferation of VSMC, because they are completely free from mechanical and neurohumoral influence. Therefore, the present study was de
