標(biāo)題: Titlebook: Epigenetics: Development and Disease; Tapas K. Kundu Book 2013 Springer Science+Business Media Dordrecht 2013 Cancer and diabetes.Chromati [打印本頁] 作者: 切口 時間: 2025-3-21 16:49
書目名稱Epigenetics: Development and Disease影響因子(影響力)
書目名稱Epigenetics: Development and Disease影響因子(影響力)學(xué)科排名
書目名稱Epigenetics: Development and Disease網(wǎng)絡(luò)公開度
書目名稱Epigenetics: Development and Disease網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Epigenetics: Development and Disease被引頻次
書目名稱Epigenetics: Development and Disease被引頻次學(xué)科排名
書目名稱Epigenetics: Development and Disease年度引用
書目名稱Epigenetics: Development and Disease年度引用學(xué)科排名
書目名稱Epigenetics: Development and Disease讀者反饋
書目名稱Epigenetics: Development and Disease讀者反饋學(xué)科排名
作者: Truculent 時間: 2025-3-21 22:16
Secondary Structures of the Core Histone N-terminal Tails: Their Role in Regulating Chromatin Structhe crystal. This suggested that the tails contributed minimally to chromatin structure. However, . studies have shown that the tails were involved in a range of intra- and inter-nucleosomal as well as inter-fibre contacts. The H4 tail, which is essential for chromatin compaction, was shown to contac作者: 裝勇敢地做 時間: 2025-3-22 04:22 作者: EXCEL 時間: 2025-3-22 08:15
Role of DNA Methyltransferases in Epigenetic Regulation in Bacteriaeneration to generation with no alterations in the DNA sequence and represent the epigenetic signal in prokaryotes. DNA methyltransferases are enzymes involved in DNA modification and thus in epigenetic regulation of gene expression. DNA methylation not only affects the thermodynamic stability of DN作者: Assault 時間: 2025-3-22 09:20
Metabolic Aspects of Epigenome: Coupling of ,-Adenosylmethionine Synthesis and Gene Regulation on Chup. SAM is biosynthesized by methionine adenosyltransferase (MAT) using two substrates, methionine and ATP. Three distinct forms of MAT (MATI, MATII and MATIII), encoded by two distinct genes (. and .), have been identified in mammals. MATII consists of α2 catalytic subunit encoded by . and β regula作者: cylinder 時間: 2025-3-22 13:38 作者: cylinder 時間: 2025-3-22 18:37 作者: 原告 時間: 2025-3-22 22:50
Small Changes, Big Effects: Chromatin Goes Aging0). Efforts to understanding the mechanisms that extend or shorten lifespan have been made since the early twentieth century. Aging is characteristically associated with a progressive decline in the overall fitness of the organism. Several studies have provided valuable information about the molecul作者: 謙卑 時間: 2025-3-23 03:21 作者: 擔(dān)憂 時間: 2025-3-23 08:55
Basic Mechanisms in RNA Polymerase I Transcription of the Ribosomal RNA Genesng many fundamental cellular processes. Extensive research into the mechanisms governing transcription by Pol I has revealed an intricate set of control mechanisms impinging upon rRNA production. Pol I-specific transcription factors guide Pol I to the rDNA promoter and contribute to multiple rounds 作者: 熟練 時間: 2025-3-23 11:14
The RNA Polymerase II Transcriptional Machinery and Its Epigenetic Contextity, Pol II is subject to a host of factors that regulate the multistep transcription process. Indeed, the hallmark of the transcription cycle is the dynamic association of Pol II with initiation, elongation and other factors. In addition, Pol II transcription is regulated by a series of cofactors (作者: ECG769 時間: 2025-3-23 16:10 作者: Watemelon 時間: 2025-3-23 21:18
The Role of DNA Methylation and Histone Modifications in Transcriptional Regulation in Humanse, transcriptional regulation still cannot be explained solely by an individual’s DNA sequence. Complex coordination and communication between a plethora of well-conserved chromatin modifying factors are essential for all organisms. Regulation of gene expression depends on histone post translational作者: 賄賂 時間: 2025-3-23 23:55
Histone Variants and Transcription Regulationed during S phase of the cell cycle, there exist variants of canonical histones that are expressed throughout the cell cycle. These histone variants are often deposited at defined regions of the genome and they play important roles in a variety of cellular processes, such as transcription regulation作者: 柔聲地說 時間: 2025-3-24 04:27 作者: 接合 時間: 2025-3-24 07:20
Chromatin Structure and Organization: The Relation with Gene Expression During Development and Diseaen chromatin domains and ultimately chromosome territories. These successive folding levels rely on the formation of chromatin loops ranging from few kb to some Mb. In addition to a packaging and structural role, the high-order organization of genomes functionally impacts on gene expression program.作者: eczema 時間: 2025-3-24 14:12 作者: 殘酷的地方 時間: 2025-3-24 17:03 作者: 葡萄糖 時間: 2025-3-24 20:08 作者: 俗艷 時間: 2025-3-24 23:14
Metabolic Aspects of Epigenome: Coupling of ,-Adenosylmethionine Synthesis and Gene Regulation on Chepression by MafK and its partner Bach1. Because the catalytic activity of MATIIα is required for the MafK target gene repression, MATIIα is suggested to provide SAM locally on chromatin where it is recruited. One of the unexpected features of MATII is that MATIIα interacts with many chromatin-relat作者: 管理員 時間: 2025-3-25 05:01 作者: modifier 時間: 2025-3-25 09:24
Epigenetic Regulation of Skeletal Muscle Development and DifferentiationEF2 activites. Among these, histone deacetylases (HDACs), histone acetyltransferases (HATs), histone methyltransferases (HMTs) and SWI/SNF complexes alter chromatin structure through post-translational modifications to impact MRF and MEF2 activities. With such new and emerging knowledge, we are begi作者: GOAD 時間: 2025-3-25 13:50 作者: annexation 時間: 2025-3-25 16:03 作者: 聰明 時間: 2025-3-25 20:41
RNA Polymerase III Transcription – Regulated by Chromatin Structure and Regulator of Nuclear Chromategulator and genome organizer CCCTC-binding factor (CTCF). Furthermore, chromosomal sites have been identified in yeast and humans that are bound by partial Pol III machineries (extra TFIIIC sites – ETC; chromosome organizing clamps – COC). These ETCs/COC as well as Pol III genes possess the ability作者: 諂媚于性 時間: 2025-3-26 02:19
The Role of DNA Methylation and Histone Modifications in Transcriptional Regulation in Humansstates at the stage of altered gene expression. Utilizing information gained from new high-throughput techniques and analyses will aid biomedical research in the development of treatments that work at one of the most basic levels of gene expression, chromatin. This chapter will discuss the effects o作者: Resign 時間: 2025-3-26 05:37 作者: Cacophonous 時間: 2025-3-26 09:48 作者: 大范圍流行 時間: 2025-3-26 12:42
https://doi.org/10.1007/978-94-009-6009-1d that post-translational modifications of the tails had a major impact on these structures. Circular dichroism and NMR showed that the H3 and H4 tails exhibited significant α-helical content, that was increased by acetylation of the tail. There is thus strong evidence, both from biophysical and fro作者: 敲詐 時間: 2025-3-26 20:46 作者: Talkative 時間: 2025-3-26 22:37
John P. Kostuik,Robert GillespieDNA methlytransferases novel targets for the designing of therapeutics. Here, we summarize the current knowledge about the influence of DNA methylation on gene regulation in different bacteria, and on bacterial virulence.作者: 大吃大喝 時間: 2025-3-27 04:53 作者: Exploit 時間: 2025-3-27 08:03 作者: 袋鼠 時間: 2025-3-27 10:07
https://doi.org/10.1007/978-3-662-39563-9EF2 activites. Among these, histone deacetylases (HDACs), histone acetyltransferases (HATs), histone methyltransferases (HMTs) and SWI/SNF complexes alter chromatin structure through post-translational modifications to impact MRF and MEF2 activities. With such new and emerging knowledge, we are begi作者: 歌劇等 時間: 2025-3-27 14:19 作者: 植物茂盛 時間: 2025-3-27 20:05 作者: ICLE 時間: 2025-3-27 22:20 作者: 缺乏 時間: 2025-3-28 06:00
https://doi.org/10.1007/978-3-662-39565-3states at the stage of altered gene expression. Utilizing information gained from new high-throughput techniques and analyses will aid biomedical research in the development of treatments that work at one of the most basic levels of gene expression, chromatin. This chapter will discuss the effects o作者: 口訣 時間: 2025-3-28 07:25
978-94-017-7996-8Springer Science+Business Media Dordrecht 2013作者: deciduous 時間: 2025-3-28 13:54
Epigenetics: Development and Disease978-94-007-4525-4Series ISSN 0306-0225 Series E-ISSN 2542-8810 作者: LIKEN 時間: 2025-3-28 17:37 作者: pulse-pressure 時間: 2025-3-28 21:53
https://doi.org/10.1007/978-94-009-6009-1he crystal. This suggested that the tails contributed minimally to chromatin structure. However, . studies have shown that the tails were involved in a range of intra- and inter-nucleosomal as well as inter-fibre contacts. The H4 tail, which is essential for chromatin compaction, was shown to contac作者: jet-lag 時間: 2025-3-29 00:48 作者: ALIEN 時間: 2025-3-29 04:25
John P. Kostuik,Robert Gillespieeneration to generation with no alterations in the DNA sequence and represent the epigenetic signal in prokaryotes. DNA methyltransferases are enzymes involved in DNA modification and thus in epigenetic regulation of gene expression. DNA methylation not only affects the thermodynamic stability of DN作者: 喚醒 時間: 2025-3-29 08:01
The British Caribbean World: Barbados,up. SAM is biosynthesized by methionine adenosyltransferase (MAT) using two substrates, methionine and ATP. Three distinct forms of MAT (MATI, MATII and MATIII), encoded by two distinct genes (. and .), have been identified in mammals. MATII consists of α2 catalytic subunit encoded by . and β regula作者: Ointment 時間: 2025-3-29 14:30
https://doi.org/10.1007/978-3-662-39557-8and fertilization of an egg. Germ cells are unique in their capability to generate new organisms, and extra caution has to be taken to secure the correct inheritance of genetic and epigenetic information. Male germ cells are epigenetically distinct from somatic cells and they undergo several importa作者: aptitude 時間: 2025-3-29 15:34
https://doi.org/10.1007/978-3-662-39563-9s a series of steps in which cells are commited towards the myogenic lineage, undergo expansion to give rise to myoblasts that differentiate into multinucleated myotubes, and mature to form adult muscle fibers. The commitment, proliferation, and differentiation of progenitor cells involve both genet作者: 領(lǐng)導(dǎo)權(quán) 時間: 2025-3-29 20:37
https://doi.org/10.1007/978-3-662-39561-50). Efforts to understanding the mechanisms that extend or shorten lifespan have been made since the early twentieth century. Aging is characteristically associated with a progressive decline in the overall fitness of the organism. Several studies have provided valuable information about the molecul作者: bisphosphonate 時間: 2025-3-30 03:14
https://doi.org/10.1007/978-3-662-39558-5igher order of chromatin organization is established during development and dynamically maintained throughout the life span. Developmental mechanisms are conserved in bilaterians and hence they have body plan in common, which is achieved by regulatory networks controlling cell type specific gene exp作者: 壓迫 時間: 2025-3-30 05:59
https://doi.org/10.1007/978-3-662-39562-2ng many fundamental cellular processes. Extensive research into the mechanisms governing transcription by Pol I has revealed an intricate set of control mechanisms impinging upon rRNA production. Pol I-specific transcription factors guide Pol I to the rDNA promoter and contribute to multiple rounds 作者: 聯(lián)想 時間: 2025-3-30 09:07
https://doi.org/10.1007/978-3-662-39501-1ity, Pol II is subject to a host of factors that regulate the multistep transcription process. Indeed, the hallmark of the transcription cycle is the dynamic association of Pol II with initiation, elongation and other factors. In addition, Pol II transcription is regulated by a series of cofactors (作者: resilience 時間: 2025-3-30 13:53
https://doi.org/10.1007/978-3-662-39564-6tones, such as acetylation, phosphorylation and methylation have been linked to Pol III transcriptional activity. In addition to being regulated by modifications of DNA and histones, Pol III genes and its transcription factors have been implicated in the organization of nuclear chromatin in several 作者: jocular 時間: 2025-3-30 18:36
https://doi.org/10.1007/978-3-662-39565-3e, transcriptional regulation still cannot be explained solely by an individual’s DNA sequence. Complex coordination and communication between a plethora of well-conserved chromatin modifying factors are essential for all organisms. Regulation of gene expression depends on histone post translational作者: Militia 時間: 2025-3-31 00:01
