標(biāo)題: Titlebook: Epigenetics of Aging; Trygve O. Tollefsbol Book 2010 Springer-Verlag New York 2010 Chromosom.DNA.Telomere.aging.genetics.senescence [打印本頁(yè)] 作者: 連續(xù)不斷 時(shí)間: 2025-3-21 16:28
書目名稱Epigenetics of Aging影響因子(影響力)
書目名稱Epigenetics of Aging影響因子(影響力)學(xué)科排名
書目名稱Epigenetics of Aging網(wǎng)絡(luò)公開度
書目名稱Epigenetics of Aging網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Epigenetics of Aging被引頻次
書目名稱Epigenetics of Aging被引頻次學(xué)科排名
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書目名稱Epigenetics of Aging年度引用學(xué)科排名
書目名稱Epigenetics of Aging讀者反饋
書目名稱Epigenetics of Aging讀者反饋學(xué)科排名
作者: 結(jié)束 時(shí)間: 2025-3-21 21:00
Age-Related Genomic Hypomethylationhe mammalian epigenome, including hypomethylation of DNA. DNA methylation is a crucial biological process that controls maintenance of genomic integrity and an accurate expression of genetic information. The accurate status of DNA methylation is balanced in mature cells, but with age this balance is作者: judicial 時(shí)間: 2025-3-22 04:25 作者: 不可知論 時(shí)間: 2025-3-22 06:20 作者: Discrete 時(shí)間: 2025-3-22 10:36 作者: 伴隨而來 時(shí)間: 2025-3-22 14:46 作者: 伴隨而來 時(shí)間: 2025-3-22 18:42 作者: enlist 時(shí)間: 2025-3-22 23:40 作者: 小口啜飲 時(shí)間: 2025-3-23 04:49
Chromosomal Position Effect and Agingstructure and function throughout life play a pivotal role in this irreversible physiological process by affecting gene expression, replication, recombination, DNA repair, and epigenetic programming. Upon exogenous stress or simply as the result of cellular metabolism and cellular division, DNA rear作者: Acumen 時(shí)間: 2025-3-23 08:43
Noncoding RNA for Presymptomatic Diagnosis of Age-Dependent Diseasemerous incremental programmatic shifts to dysfunctional states. Most current therapeutic treatments address illnesses characterizing the elderly symptomatically, largely attempting to reduce the severity of the disease rather than delaying or preventing its occurrence; this retrospective strategy is作者: organism 時(shí)間: 2025-3-23 10:12 作者: 腐爛 時(shí)間: 2025-3-23 16:06
Telomeres, Epigenetics, and Aging telomere function. How both aspects are connected and how they impact on organismal fitness will be the subject of intense research in the coming years. This chapter reviews different aspects of telomere biology and discusses their implications in the aging process.作者: COM 時(shí)間: 2025-3-23 18:53 作者: ANIM 時(shí)間: 2025-3-23 23:11 作者: Aerate 時(shí)間: 2025-3-24 05:33
Contributions of Tumor Suppressors to the Epigenetic Regulation of Aging Cells. Covalent modifications of histones and DNA methylation are the most common epigenetic modifications that influence the activity of various growth stimulatory and inhibitory genes. Cellular senescence might be viewed as a state when the “balance” of gene activity is skewed in the favour of growth i作者: infantile 時(shí)間: 2025-3-24 07:26
Book 2010sses, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an imp作者: CANON 時(shí)間: 2025-3-24 13:34
Vertriebsbedingte Erfolgsursachen,compacting DNA. The balance between the activity of HATs and HDACs regulates transcription, but with aging this balance is lost, leading to either gene overactivity (e.g., in cancer cells) or gene repression that can lead to neurodegeneration during the aging process.作者: 滲入 時(shí)間: 2025-3-24 17:45 作者: Genteel 時(shí)間: 2025-3-24 20:13 作者: ATRIA 時(shí)間: 2025-3-24 23:15 作者: acrimony 時(shí)間: 2025-3-25 07:04 作者: 寬度 時(shí)間: 2025-3-25 08:11 作者: coalition 時(shí)間: 2025-3-25 15:16 作者: Hdl348 時(shí)間: 2025-3-25 17:54 作者: Platelet 時(shí)間: 2025-3-25 20:06 作者: 矛盾心理 時(shí)間: 2025-3-26 01:10 作者: 鋪?zhàn)?nbsp; 時(shí)間: 2025-3-26 07:51
Role of Epigenetics in Age-Related Long-Term Memory Lossry loss is best seen by studying the classic age-related disease, Alzheimer’s disease (AD), which is characterized by severe memory loss. Biological aging correlates with a loss of expression and activity of certain epigenetic modulating enzymes, such as DNA methyltransferase1. The loss of maintenan作者: 提名的名單 時(shí)間: 2025-3-26 12:30 作者: archetype 時(shí)間: 2025-3-26 15:51
many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an imp978-1-4899-8310-7978-1-4419-0639-7作者: 憤慨一下 時(shí)間: 2025-3-26 17:25 作者: 混沌 時(shí)間: 2025-3-26 21:42 作者: 控制 時(shí)間: 2025-3-27 02:59 作者: ornithology 時(shí)間: 2025-3-27 06:40 作者: 松果 時(shí)間: 2025-3-27 13:09 作者: URN 時(shí)間: 2025-3-27 16:52 作者: 構(gòu)成 時(shí)間: 2025-3-27 18:35
https://doi.org/10.1007/978-3-663-02303-6portant role of sirtuins in a variety of biological processes, including transcription regulation, apoptosis, DNA repair, metabolism, and more prominently, aging. Sirtuins regulate lifespan in evolutionarily diverse species partly through modulating calorie restriction pathways. Sirtuins link the nu作者: menopause 時(shí)間: 2025-3-28 00:50 作者: Outmoded 時(shí)間: 2025-3-28 03:56
https://doi.org/10.1007/978-3-662-39566-0002; Toescu et al., 2004; Park and Prolla, 2005; Englander, 2005). As such, a number of studies have focused on the mechanism(s) underlying these changes in an attempt to identify conserved pathways altered during aging. Methylation of DNA is a critical epigenetic mechanism regulating gene expressio作者: 角斗士 時(shí)間: 2025-3-28 10:11
Vertriebsbedingte Erfolgsursachen, gene transcription. Modification of histones and/or DNA can alter the strength of their association and thus, together, modulate transcriptional activity. Acetylation of histones neutralizes their positively charged, lysine-rich amino-terminal tails, loosening the histone–DNA contacts, thus making 作者: Generosity 時(shí)間: 2025-3-28 12:00
https://doi.org/10.1007/978-3-476-05503-3ajority of methyltransferases that modify DNA, RNA, histones, and many other proteins such as Tp53, lipids, and a variety of other small molecules including toxic compounds, such as arsenic, whose actions affect replication, transcription, and translation, DNA repair and chromatin modeling, epigenet作者: 吹氣 時(shí)間: 2025-3-28 15:36
Volksstruktur und sozialer Gedankem the early development through the entire life span of an individual. This evolutionarily well–conserved group of proteins create and maintain epigenetic chromatin marks that are translated into means of maintaining a temporally and spatially regulated gene expression status. Among the many differe作者: 狗舍 時(shí)間: 2025-3-28 20:45 作者: Panther 時(shí)間: 2025-3-28 23:15
Amerikanische und deutsche Gro?dampfkesselmerous incremental programmatic shifts to dysfunctional states. Most current therapeutic treatments address illnesses characterizing the elderly symptomatically, largely attempting to reduce the severity of the disease rather than delaying or preventing its occurrence; this retrospective strategy is作者: custody 時(shí)間: 2025-3-29 06:21 作者: homocysteine 時(shí)間: 2025-3-29 08:05 作者: 的’ 時(shí)間: 2025-3-29 11:56
Willi Paul Adams,Erich Angermannstone modification, are determinants of normal development and can change during aging. Some of the epigenetic alterations described during aging, as hypermethylation at specific promoters and decrease of global DNA methylation, are also associated with tumour development. The epigenetic changes occ作者: 女歌星 時(shí)間: 2025-3-29 19:15
Amerikastudien / American Studiesg the expression of genes involved in memory processes. In fear conditioned mice, CpG islands in the promoter regions of the memory-linked genes, . and ., undergo either hypomethylation . or hypermethylation .. By altering the expression of these genes, epigenetic mechanisms can affect the ability t作者: 濃縮 時(shí)間: 2025-3-29 21:32 作者: MONY 時(shí)間: 2025-3-30 03:39 作者: 樂章 時(shí)間: 2025-3-30 07:55
https://doi.org/10.1007/978-3-322-96216-4 telomere function. How both aspects are connected and how they impact on organismal fitness will be the subject of intense research in the coming years. This chapter reviews different aspects of telomere biology and discusses their implications in the aging process.作者: Morphine 時(shí)間: 2025-3-30 09:57
Chromatin in Senescent Cells: A Conduit for the Anti-Aging Effects of Wnt Signaling? evidence that Wnt signaling can be both pro- and anti-aging. Here we discuss the idea that, in at least some cell and tissue contexts, Wnt signaling might antagonize aging through its ability to regulate chromatin structure in senescent cells.作者: 信條 時(shí)間: 2025-3-30 12:32 作者: 衣服 時(shí)間: 2025-3-30 17:39 作者: 攝取 時(shí)間: 2025-3-30 21:13
Kurt H. Stapf,Wolfgang Stroebe,Klaus Jonasontributing to the development of chronic age-related human pathological states. This review describes the involvement of DNA hypomethylation in the pathogenesis of several major age-related human diseases, including cancer, atherosclerosis, Alzheimer’s disease, psychiatric disorders, and autoimmune pathologies.
