標題: Titlebook: Enzymology and Molecular Biology of Carbonyl Metabolism 7; Henry Weiner,Edmund Maser,Ronald Lindahl Book 1999 The Editor(s) (if applicable [打印本頁] 作者: PEL 時間: 2025-3-21 19:22
書目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 7影響因子(影響力)
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書目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 7網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 7被引頻次
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書目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 7年度引用學(xué)科排名
書目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 7讀者反饋
書目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 7讀者反饋學(xué)科排名
作者: 無彈性 時間: 2025-3-21 21:17
https://doi.org/10.1007/978-3-031-04349-9y closely related homotetramers and both participate in ethanol metabolism, though class 1 ALDH. can oxidize wide range of metabolites, including retinal (reviewed Lindahl, 1982; Yoshida et al., 1). Class 3 ALDH. appear at first glance to be highly divergent from the other 2 classes. Class 3 ALDH. s作者: MURKY 時間: 2025-3-22 01:51 作者: 污穢 時間: 2025-3-22 05:12 作者: 中子 時間: 2025-3-22 10:53 作者: 王得到 時間: 2025-3-22 13:07 作者: 王得到 時間: 2025-3-22 19:12
Poverty, Food Security, and Nutritionlaboratory. The initial studies suggested that the enzyme functioned with covalent catalysis and that a cysteine might be the nucleophile (Feldman and Weiner, 1972). It was later shown by chemical modifications that cysteine 302 was at the active site and it most likely functioned as the nucleophile作者: 顯赫的人 時間: 2025-3-23 00:42 作者: 無能的人 時間: 2025-3-23 02:33 作者: 噱頭 時間: 2025-3-23 08:12
Palgrave Studies in Economic History cytotoxic, aldehydic products (Esterbauer ., 1991). 4-hydroxy-2-.-nonenal (4-HNE) malondialdehyde (MDA), the most abundant aldehydes produced during lipid peroxidation, have a relatively long half-life and are capable of diffusing to distant sites within the cell of origin or into adjacent cells. 4作者: 束縛 時間: 2025-3-23 13:45 作者: Ingrained 時間: 2025-3-23 16:38
SpringerBriefs in Environmental Sciencenow generally believed that the dehydrogenase and esterase actions of the enzyme involve the same active site and catalytic groups (see Kitson and Kitson, 1996, and references therein). With . -nitrophenyl dimethylcarbamate, the reactivity (compared to the acetate) is so drastically reduced that it 作者: Formidable 時間: 2025-3-23 22:06 作者: 變態(tài) 時間: 2025-3-23 23:15 作者: EVADE 時間: 2025-3-24 04:20 作者: 欺騙手段 時間: 2025-3-24 08:45
Trade, Uncertainty, and New Farm Programsformed from the reaction of carbon-centered radicals with molecular oxygen (Esterbauer ., 1991; Schauer ..990). Four-hydroxynonenal (4-HNE) and other endogenous and exogenous aldehydes, such as malondialdehyde and acrolein, are also generated in response to a variety of oxidative stimuli including f作者: theta-waves 時間: 2025-3-24 13:01
Seema Bathla,Pramod Kumar Joshi,Anjani Kumarenous toxic aldehydes (Linda 1992; Yoshida, 1992) and against endogenous aldehydes, such as those derived from ld peroxidation (Lindahl and Petersen, 1991; Canuto et al., 1994). The latter appear to influence cell growth and differentiation in some tumour cell lines (Barrera et al., 1994; Canuto et 作者: 減弱不好 時間: 2025-3-24 16:53
https://doi.org/10.1057/9780230372238hey are present in tobacco smoke, exhaust fumes and urban air. PAHs are also found in water and soil as a result the rain and gravitational influence providing other possible routes for human exposure (Wills and Weisburger, 1986). Benzo[a]pyrene (BP) is a potent inducer of drug- metabolizing enzymes作者: 混亂生活 時間: 2025-3-24 19:37
Agricultural Innovation in AsiaDifferent consti- tutiveexpressed ALDHs are found in liver, stomach, brain, kidney, skin and eye (Vasil and Marselos, 1989; Pappas et al., 1997). In general, ALDHs are located especially in org with a high content of epithelial cells. An increased interest has been shown r the last years for aldehyd作者: GULF 時間: 2025-3-25 00:55 作者: 杠桿 時間: 2025-3-25 04:22 作者: 花束 時間: 2025-3-25 10:21
Enzymology and Molecular Biology of Carbonyl Metabolism 7978-1-4615-4735-8Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: curriculum 時間: 2025-3-25 11:41
Sapna Tyagi,Deepak Rajpurohit,Amit Sharma arrive at the consensus of invariable residues that are essential for catalysis; a conserved feature during evolution. Thus, 16 different aldehyde dehydrogenases were compared by Hempel et al., (1993)who found 23 invariable amino acid residues by alignment of sequences available at that time.作者: NUL 時間: 2025-3-25 17:42 作者: medium 時間: 2025-3-25 20:09
Reaction-Chemistry-Directed Sequence Alignment of Aldehyde Dehydrogenases arrive at the consensus of invariable residues that are essential for catalysis; a conserved feature during evolution. Thus, 16 different aldehyde dehydrogenases were compared by Hempel et al., (1993)who found 23 invariable amino acid residues by alignment of sequences available at that time.作者: 微生物 時間: 2025-3-26 02:24
Effect of Arachidonic Acid Alone or with Prooxidant on Aldehyde Dehydrogenases in Hepatoma Cellsenous toxic aldehydes (Linda 1992; Yoshida, 1992) and against endogenous aldehydes, such as those derived from ld peroxidation (Lindahl and Petersen, 1991; Canuto et al., 1994). The latter appear to influence cell growth and differentiation in some tumour cell lines (Barrera et al., 1994; Canuto et al., 1995).作者: 畏縮 時間: 2025-3-26 07:16
The Externalization of Agricultureechanism (Liu et al., 1997b)he position of NAD in an isomorphous class 3 ALDH derivative and the emergence of Asn4/169 as a strictly conserved residue prompted us to consider the catalytic mechanism we present here.作者: 發(fā)展 時間: 2025-3-26 10:49 作者: HIKE 時間: 2025-3-26 14:54
Agricultural Innovation in Asialso tpresence of ALDH1 as the 1-2% of human lens soluble protein. Furthermore, retina and real pigment epithelial (RPE) cells have been shown to play an important protective role fthe photosensitive cells of the eye against photo- and chemical toxicity.作者: Watemelon 時間: 2025-3-26 18:26 作者: CAMP 時間: 2025-3-27 00:53 作者: 裝飾 時間: 2025-3-27 03:51
Effects of Tamoxifen and Toremifene on ALDH1 and ALDH3 in Human Retinal Pigment Epithelial Cells andlso tpresence of ALDH1 as the 1-2% of human lens soluble protein. Furthermore, retina and real pigment epithelial (RPE) cells have been shown to play an important protective role fthe photosensitive cells of the eye against photo- and chemical toxicity.作者: Anthem 時間: 2025-3-27 06:50 作者: ALLAY 時間: 2025-3-27 11:53 作者: Grievance 時間: 2025-3-27 15:38
Control of Agricultural Production Systems,98) are kn in three-dimensional structure (Liu et al., 1997; Steinmetz et al., 1997; Johansson et al.998), several have not been purified and characterized enzymatically, and little is known about their species or class variabilities.作者: 尊敬 時間: 2025-3-27 18:10 作者: 猛擊 時間: 2025-3-27 23:56 作者: 遵循的規(guī)范 時間: 2025-3-28 05:54 作者: Somber 時間: 2025-3-28 09:07 作者: 無關(guān)緊要 時間: 2025-3-28 10:27 作者: 合群 時間: 2025-3-28 17:39
Inhibition of Human Mitochondrial Aldehyde Dehydrogenase by Metabolites of Disulfiram and Structural . to .-diethyldithiocarbamate (DDC) (Cobby .., 1977) which is further metabolized as shown in Scheme 1. The general consensus is that disulfiram is too short-lived . to account for the inhibition of ALDH2 that one its metabolites is the ultimate inhibitor (Yourick & Faiman, 1991; Hart & man, 1992).作者: Jacket 時間: 2025-3-28 22:12 作者: TEN 時間: 2025-3-29 02:29
The Big Book of Aldehyde Dehydrogenase Sequenceshare only about 25% sequence identity with class 1 and 2 ALDHs and are homodimers. However, in main-chain folding, the structures of the class 2 and 3 monomers are nearly identical (Hempel et al., 1999)作者: avulsion 時間: 2025-3-29 03:39
Book 1999inth meeting. She quickly suggested that both she and Dr. Guiliana Muzio, also of Turin, help plan the meet- ing. Each of our previous eight meetings was a unique experience for the participants. The science was always outstanding and the presentations and discussions were excellent. By moving each 作者: 臭了生氣 時間: 2025-3-29 08:19
The Big Book of Aldehyde Dehydrogenase Sequencesy closely related homotetramers and both participate in ethanol metabolism, though class 1 ALDH. can oxidize wide range of metabolites, including retinal (reviewed Lindahl, 1982; Yoshida et al., 1). Class 3 ALDH. appear at first glance to be highly divergent from the other 2 classes. Class 3 ALDH. s作者: CLAMP 時間: 2025-3-29 15:23
Reaction-Chemistry-Directed Sequence Alignment of Aldehyde Dehydrogenases arrive at the consensus of invariable residues that are essential for catalysis; a conserved feature during evolution. Thus, 16 different aldehyde dehydrogenases were compared by Hempel et al., (1993)who found 23 invariable amino acid residues by alignment of sequences available at that time.作者: Engulf 時間: 2025-3-29 18:37 作者: 異端邪說下 時間: 2025-3-29 20:32 作者: 表示問 時間: 2025-3-30 03:47
Structure and Function of Betaine Aldehyde Dehydrogenasehways. However, they are derived from separate protein families with distinct properties. Those of the vertebrate ADHs have been well characterized since long, and their different classes belong to the MDR protein family of known structures from several sources. However, the properties and multiplic作者: minaret 時間: 2025-3-30 05:04 作者: 藐視 時間: 2025-3-30 08:24
Aldehyde Dehydrogenase Catalytic Mechanismted that the crystal structure of a class 3 ALDH (E-NAD binary complex) revealed a non-traditional mode of NAD-binding within an open β/α domain otherwise familiar in the NAD-binding “ossmann folds” of other dehydrogenases (Liu et al., 1997a). The variability of residues in the substrate-binding sit作者: 手工藝品 時間: 2025-3-30 14:54
Inhibition of Human Mitochondrial Aldehyde Dehydrogenase by Metabolites of Disulfiram and Structuralase (ALDH2), a key ene by virtue of its low K. for acetaldehyde (Mascher & Kikuta, 1992; Greenfield & Pietruszko, 1977). Disulfiram is rapidly reduced . to .-diethyldithiocarbamate (DDC) (Cobby .., 1977) which is further metabolized as shown in Scheme 1. The general consensus is that disulfiram is t作者: oxidant 時間: 2025-3-30 18:38
Mechanism of Inhibition of Rat Liver Class 2 ALDH by 4-Hydroxynonenal cytotoxic, aldehydic products (Esterbauer ., 1991). 4-hydroxy-2-.-nonenal (4-HNE) malondialdehyde (MDA), the most abundant aldehydes produced during lipid peroxidation, have a relatively long half-life and are capable of diffusing to distant sites within the cell of origin or into adjacent cells. 4作者: 樹膠 時間: 2025-3-30 22:07 作者: 單挑 時間: 2025-3-31 01:30 作者: 搬運工 時間: 2025-3-31 08:55
A Thioester Analogue of an Amino Acetylenic Aldehyde Is A Suicide Inhibitor of Aldehyde Dehydrogenastanoic acid (B), an intermediate in the methionine salvage pathway is a potent inducer of apoptosis when added to cultures of mouse lymphoid cells BAF. bo (Quash et al., 1995). MTOB a00 μM was also capable of alleviating the methionine dependence shown by transfed cells (Ogier et al., 1993) because 作者: 智力高 時間: 2025-3-31 12:02
Reaction between Sheep Liver Mitochondrial Aldehyde Dehydrogenase and A Chromogenic ‘Reporter Group’ and giving an inactive from the enzyme in which Cys-302 carries a -CO-NMe. label (Kitson et al., 1991) is work led to the idea that a cyclic analogue of the carbamate would constitute a ‘eporter group’ reagent of the type originally envisaged by Burr and Koshland (1964), since the chromophoric .-ni作者: 走調(diào) 時間: 2025-3-31 14:50 作者: 柱廊 時間: 2025-3-31 17:58
