標(biāo)題: Titlebook: Enzymology and Molecular Biology of Carbonyl Metabolism 6; Henry Weiner,Ronald Lindahl,T. Geoffrey Flynn Book 1997 The Editor(s) (if appli [打印本頁(yè)] 作者: Lampoon 時(shí)間: 2025-3-21 17:33
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6影響因子(影響力)
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6影響因子(影響力)學(xué)科排名
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6被引頻次
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6被引頻次學(xué)科排名
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6年度引用
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6年度引用學(xué)科排名
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6讀者反饋
書(shū)目名稱Enzymology and Molecular Biology of Carbonyl Metabolism 6讀者反饋學(xué)科排名
作者: 上坡 時(shí)間: 2025-3-21 20:46
Conserved Residues in the Aldehyde Dehydrogenase Family,d in binding NAD, its role is completely different from that observed for the first glycine residue of the GXGXXG motif in other dehydrogenases with traditional Rossmann folds. It was thus of interest, once the sequence was fit into the electron density, to examine the locations of strictly conserve作者: Somber 時(shí)間: 2025-3-22 04:25 作者: 嚴(yán)峻考驗(yàn) 時(shí)間: 2025-3-22 04:57
Human Corneal and Lens Aldehyde Dehydrogenases,n human ALDHs have been reported, of which ALDH1, 2, 3, 5, 6, and 7 (Hsu et al, 1994), and a related enzyme, γ-amino butyraldehyde dehydrogenase (GABADH) (Kurys et al, 1993), have been thus far cloned and sequenced (Hsu et al., 1994). Sequence analysis verifies that these are closely related enzymes作者: bronchiole 時(shí)間: 2025-3-22 11:14 作者: Aviary 時(shí)間: 2025-3-22 14:38 作者: Aviary 時(shí)間: 2025-3-22 17:21
Changes in Aldehyde Dehydrogenase Isozymes Expression in Long-Term Cultures of Human Hematopoietic us bone marrow samples before reinfusion (Beran et al., 1987; Yeager et al., 1990; Carlo-Stella et al., 1994). Recently published studies from many laboratories including our own have unequivocally established that there is an associative as well as causative inverse relationship between cellular co作者: Decimate 時(shí)間: 2025-3-22 22:21
Expression of ALDH3 and NMO1 in Human Corneal Epithelial and Breast Adenocarcinoma Cells,989). The hazards of UV light exposure to the eye have been recognized since the early 1900’s (van der Hoeve, 1920). Exposure to UV radiation has been linked to acute keratitis and other disorders of the ocular surface (Schein, 1992). Protein modification, extensive DNA damage and generation of reac作者: CEDE 時(shí)間: 2025-3-23 03:33
A Preliminary Report on the Cloning of a Constitutively Expressed Rat Liver Cytosolic ALDH cDNA by . ALDH is located in virtually all mammalian tissues and found in all major subcellular organelles. The hepatic cDNAs for phenobarbital(PB)-inducible cytosolic ALDH, mitochondrial ALDH, microsomal ALDH, and tumor specific cytosolic ALDH have been cloned in the rat (Dunn, ., 1989; Farres, ., 1989; Mi作者: 令人心醉 時(shí)間: 2025-3-23 07:32 作者: Evolve 時(shí)間: 2025-3-23 11:58 作者: fulmination 時(shí)間: 2025-3-23 16:40 作者: languid 時(shí)間: 2025-3-23 18:29 作者: 并排上下 時(shí)間: 2025-3-24 00:43
In Hepatoma Cell Lines Restored Lipid Peroxidation Affects Cell Viability Inversely to Aldehyde Metcreases their capability to undergo lipid peroxidation (Gravela et al., 1975; Canuto et al., 1991; Cheeseman et al., 1988; Feo et al., 1975; Canuto et al., 1994; Masotti et al., 1988). A consequence of this is the reduced production of aldehydes inside the cells (Poli et al., 1986). Depending on the作者: Pelvic-Floor 時(shí)間: 2025-3-24 04:12 作者: Peculate 時(shí)間: 2025-3-24 07:06
Inhibition of Human Class 3 Aldehyde Dehydrogenase, and Sensitization of Tumor Cells that Express S antineoplastic prodrugs collectively referred to as oxazaphosphorines, e.g., cyclophosphamide, ifosfamide, 4-hydroperoxycyclophosphamide, 4-hydroperoxyifosfamide and mafosfamide (cellular sensitivity to these drugs decreases as cellular levels of ALDH-3 increase) (Sladek, 1993; Sreerama and Sladek,作者: Cocker 時(shí)間: 2025-3-24 12:04 作者: CURL 時(shí)間: 2025-3-24 16:09
Yeast Aldehyde Dehydrogenase Sensitivity to Inhibition by Chlorpropamide Analogues as an Indicator Based on primary structure or subcellular distribution and kinetic, physical and immunochemical properties, they have been placed into one of three classes, viz., class 1, e.g., ALDH-1, class 2, e.g., ALDH-2 and class 3, e.g., ALDH-3 (Anonymous, 1989; Lindahl and Hempel, 1990; Goedde and Agarwal, 1作者: WAIL 時(shí)間: 2025-3-24 21:20
Laser Light Scattering and Ultracentrifuge Studies on Sheep Liver Cytosolic Aldehyde Dehdyrogenase,e existence of order of mixing effects led Buckley . (1991) to propose that the tetrameric enzyme was dissociating into an inactive dimer or monomer. Gel filtration studies at pH 7.4 and at pH 5.2 confirmed that dissociation did take place significantly at pH 5.2, with the extent of the dissociation作者: 恃強(qiáng)凌弱 時(shí)間: 2025-3-25 01:32 作者: 時(shí)代錯(cuò)誤 時(shí)間: 2025-3-25 05:12
Sustainable Exploitation of Agro-Food Waste,or cell lines, except for the prostate cancer subpanel which consists of only two cell lines. The results of these tests, viz., GI., TGI and LC. values (the concentrations of an agent required to effect 50% growth inhibition, total growth inhibition and 50% cell-kill, respectively) have been, and are being, stored in an electronic database.作者: 的闡明 時(shí)間: 2025-3-25 09:47 作者: remission 時(shí)間: 2025-3-25 14:26
Class 1 and Class 3 Aldehyde Dehydrogenase Levels in the Human Tumor Cell Lines Currently Used by tor cell lines, except for the prostate cancer subpanel which consists of only two cell lines. The results of these tests, viz., GI., TGI and LC. values (the concentrations of an agent required to effect 50% growth inhibition, total growth inhibition and 50% cell-kill, respectively) have been, and are being, stored in an electronic database.作者: HALO 時(shí)間: 2025-3-25 19:51
0065-2598 ms. The 1996 meeting was no exception. Nearly 90 scientists from 15 countries met in the small city of Deadwood, South Dakota, for four days of stimulating talks and posters and incredible scenery. Once more this meeting reflected the changing trends in biochemical research. At the 1982 meeting most作者: 考博 時(shí)間: 2025-3-25 21:05
Francesca Santulli,Chiara Deganoure of the skin and the eye of human tissue to UV light (Hendee, 1989). The hazardous effects of UV light on the eye were already recognized in 1920 by van der Hoeve. By the 1920s, basal cell carcinomas of the skin were also noted.作者: 初次登臺(tái) 時(shí)間: 2025-3-26 00:55
Conserved Residues in the Aldehyde Dehydrogenase Family,d residues from our earlier multiple sequence alignment (Hempel et al., 1993). A total of 23 residues were strictly conserved in that alignment. This chapter will confine itself to an attempt to correlate the role of the strictly conserved residues in the ALDH family with the class 3 ALDH (binary complex with NAD) tertiary structure.作者: Dissonance 時(shí)間: 2025-3-26 06:18 作者: 口訣 時(shí)間: 2025-3-26 09:06
Profiles of Hepatic Cellular Protein Adduction by Malondialdehyde and 4-Hydroxynonenal,ury as a result of exposure to halogenated hydrocarbons, excessive alcohol ingestion, and acute or chronic iron overload (Comporti, 1985). Consistent with the auto-catalytic nature of lipid peroxoidation, each of these chemical agents can result in the production of a radical species capable of initiating lipid peroxidation.作者: 膽小懦夫 時(shí)間: 2025-3-26 13:27 作者: 圖表證明 時(shí)間: 2025-3-26 20:32 作者: MORPH 時(shí)間: 2025-3-26 22:58 作者: FLIT 時(shí)間: 2025-3-27 04:04
Elisa Martinelli,Giulia Tagliazucchicular weight of 55 kD. Class 3 ALDH preferentially uses NAD, but can use NADP. Class 3 oxidizes aromatic aldehydes such as benzaldehyde. The enzyme is a dimer of identical monomers with molecular weights of 50kD.作者: cluster 時(shí)間: 2025-3-27 09:08
Agribusiness for Economic Growth in Africaury as a result of exposure to halogenated hydrocarbons, excessive alcohol ingestion, and acute or chronic iron overload (Comporti, 1985). Consistent with the auto-catalytic nature of lipid peroxoidation, each of these chemical agents can result in the production of a radical species capable of initiating lipid peroxidation.作者: Ejaculate 時(shí)間: 2025-3-27 13:15
Agrarian Policies in Central America-hydroxynonenal derived from membrane lipid peroxidation (Lindahl and Peterson, 1991). The microsomal ALDH-3 has also received clinical attention from the recent demonstration that Sj?gren-Larsson Syndrome is the result of mutations inactivating this “fatty aldehyde dehydrogenase” (DeLaurenzi, et al, 1996).作者: flimsy 時(shí)間: 2025-3-27 17:08 作者: Hyaluronic-Acid 時(shí)間: 2025-3-27 19:38 作者: GEST 時(shí)間: 2025-3-28 01:54
Aishwarya Singhal,Jyothsna Appaiah Singhse C are stimulated (Paradisi et al., 1985; Garramone et al., 1988) and differentiation is induced in HL-60 cells (Barrera et al., 1991). At higher concentrations, 4-HNE is cytotoxic (Esterbauer et al., 1991; Canuto et al., 1995).作者: comely 時(shí)間: 2025-3-28 03:45 作者: 破譯密碼 時(shí)間: 2025-3-28 06:38 作者: 刪除 時(shí)間: 2025-3-28 12:37
Human Corneal and Lens Aldehyde Dehydrogenases,DH2, liver mitochondrial) and Class 3(ALDH3, stomach cytosolic) isozymes. In addition, a gene locus designated ALDHx, which shares 85% homology with Class 2 ALDH, has also been reported (Hsu and Chang, 1991).作者: 四溢 時(shí)間: 2025-3-28 14:45 作者: SLAG 時(shí)間: 2025-3-28 18:52 作者: keloid 時(shí)間: 2025-3-29 02:31
Aldehyde Dehydrogenase-Mediated Metabolism of Acetaldehyde and Mafosfamide in Blood of Healthy Subjoverall contribution of blood ALDH in this respect is, however, not known. In the present study, we have determined ALDH activity in human blood subfractions from healthy subjects and malignant lymphoma patients undergoing combination chemotherapy plus or minus CP.作者: 不舒服 時(shí)間: 2025-3-29 04:15 作者: 行為 時(shí)間: 2025-3-29 08:53
Book 1997l of personal interactions that went on during the meeting. Once again, the willingness of the participants to discuss unpublished data and to share thoughts about the future directions of their research helped make this, like our previous seven meetings, a special scientific experience for those wh作者: 外來(lái) 時(shí)間: 2025-3-29 12:48 作者: 偉大 時(shí)間: 2025-3-29 19:16
Regulation of Rat ALDH-3 by Hepatic Protein Kinases and Glucocorticoids,rong promoter proximal to the transcription start site, an inhibitory region just upstream of the promoter, and a PAH-responsive enhancer region approx. 3.5 kb upstream of the promoter. Expression of this gene appears to be controlled by interaction of at least these three functional domains.作者: braggadocio 時(shí)間: 2025-3-29 21:32
Mouse Dioxin-Inducible , Gene,D and peroxisome proliferators like Clofibrate (Vasiliou et al., 1996). Among these three genes, the dioxin-inducible ALDH3 is the most thoroughly studied. The gene encoding ALDH3 has been cloned in rat (Asman et al., 1993), human (Hsu et al., 1992), and mouse (termed as .; Vasiliou et al., 1994). T作者: Ptosis 時(shí)間: 2025-3-30 03:03
Expression of ALDH3 and NMO1 in Human Corneal Epithelial and Breast Adenocarcinoma Cells,d Holmes 1992). It has been suggested that ALDH3 plays a dual role to protect the cornea from the UV-light by catalyzing the oxidation of lipid per-oxidic aldehydes generated by UV-light and by absorbing UV-light itself . Boesch et al., 1996).作者: VEST 時(shí)間: 2025-3-30 04:03 作者: 挖掘 時(shí)間: 2025-3-30 08:27
Inhibition of Human Class 3 Aldehyde Dehydrogenase, and Sensitization of Tumor Cells that Express Sevated levels of this enzyme can account for intrinsic, transient acquired, and stable acquired, resistance to the oxazaphosphorines on the part of malignant cells (Sreerama and Sladek, 1993a,b, 1994; Rekha et al., 1994; Sreerama et al., 1995). Resistance to the oxazaphosphorines mediated by ALDH-3 作者: Kindle 時(shí)間: 2025-3-30 12:25 作者: Adrenaline 時(shí)間: 2025-3-30 17:38
Enzymology and Molecular Biology of Carbonyl Metabolism 6作者: magnate 時(shí)間: 2025-3-30 23:30 作者: 緯度 時(shí)間: 2025-3-31 04:09 作者: 協(xié)迫 時(shí)間: 2025-3-31 08:25 作者: 拖網(wǎng) 時(shí)間: 2025-3-31 12:03 作者: 柔聲地說(shuō) 時(shí)間: 2025-3-31 17:01
Lionella Scazzosi,Paola Branduini Hyatt, et al., 1992; Watterson, et al., 1954; McCaffery, et al., 1991; 1992; McCaffery and Dr?ger, 1993; 1994; 1995; Dr?ger and McCaffery, 1995). This is clearly seen during the anteroposterior patterning of the trunk (Marsh-Armstrong, et al., 1994) in the Zebrafish, ., in which an endogenous gradi作者: Trochlea 時(shí)間: 2025-3-31 18:02
Kénel Délusca,Christopher R. Bryantevated levels of this enzyme can account for intrinsic, transient acquired, and stable acquired, resistance to the oxazaphosphorines on the part of malignant cells (Sreerama and Sladek, 1993a,b, 1994; Rekha et al., 1994; Sreerama et al., 1995). Resistance to the oxazaphosphorines mediated by ALDH-3 作者: Indecisive 時(shí)間: 2025-4-1 00:30
Sameen Ruqia Imadi,Alvina Gul Kazirentiation; ALDH-1 and, especially, ALDH-2 catalyze the oxidation of ethanol-derived acetaldehyde to acetate, a detoxifying reaction; ALDH-3 catalyzes the oxidation of 4-hydroxynonenal and other aldehydic products of lipid peroxidation to their corresponding acids, also a detoxifying reaction; and A作者: Adulterate 時(shí)間: 2025-4-1 03:44 作者: 粘土 時(shí)間: 2025-4-1 09:35
Agrarian Policies in Central Americae identity with either of the tetrameric class 1 or 2 enzymes. Interest in the Class 3 ALDH (ALDH-3) has focused on its diversity of expression (Lindahl, 1992). No ALDH-3 activity is detectable in normal mammalian liver, but high levels are obtained after exposure to certain xenobiotics. Many neopla作者: 從容 時(shí)間: 2025-4-1 13:27
Studies in Development and Planningd in binding NAD, its role is completely different from that observed for the first glycine residue of the GXGXXG motif in other dehydrogenases with traditional Rossmann folds. It was thus of interest, once the sequence was fit into the electron density, to examine the locations of strictly conserve作者: Inkling 時(shí)間: 2025-4-1 16:30
