標(biāo)題: Titlebook: Engineering Translational Models of Lung Homeostasis and Disease; Chelsea M. Magin Book 2023 The Editor(s) (if applicable) and The Author( [打印本頁] 作者: 去是公開 時(shí)間: 2025-3-21 16:16
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書目名稱Engineering Translational Models of Lung Homeostasis and Disease被引頻次
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書目名稱Engineering Translational Models of Lung Homeostasis and Disease讀者反饋
書目名稱Engineering Translational Models of Lung Homeostasis and Disease讀者反饋學(xué)科排名
作者: collateral 時(shí)間: 2025-3-21 23:19 作者: AVID 時(shí)間: 2025-3-22 02:57 作者: forthy 時(shí)間: 2025-3-22 06:47 作者: Hemodialysis 時(shí)間: 2025-3-22 12:29
https://doi.org/10.1057/978-1-137-59445-75]. In this chapter, we highlight recent advances in the rapid development of various lung organoids, organ-on-a-chip models, and whole lung ex vivo explant models currently used to dissect the roles of these cellular signals and mechanical cues in lung development and potential avenues for future investigation (Fig. 3.1).作者: 噴油井 時(shí)間: 2025-3-22 13:48
Erich H. Loewy,Roberta Springer Loewy that allow for mechanistic studies of cell fate decisions and developmental processes. As our understanding of embryonic progenitor biology deepens, we move closer to the goal of in vitro lung organogenesis and resulting applications in developmental biology and medicine.作者: 噴油井 時(shí)間: 2025-3-22 18:07
https://doi.org/10.1057/9780230512030m both a basic physiology perspective and an engineering perspective for regenerative medicine. In this chapter, we will cover the large airways from an engineering perspective to highlight existing models of the large airways as well as future directions for modeling and repair.作者: Commodious 時(shí)間: 2025-3-23 00:42 作者: 補(bǔ)充 時(shí)間: 2025-3-23 04:01
The Etiology of Human Breast Cancer some of the scientific advances generated by those models. We discuss the use of both synthetic and naturally derived hydrogel materials, precision-cut lung slices, organoids, and lung-on-a-chip devices, with perspectives on the strengths, weaknesses, and potential future directions of these engineered systems.作者: labyrinth 時(shí)間: 2025-3-23 07:51 作者: 敵手 時(shí)間: 2025-3-23 11:38 作者: Obscure 時(shí)間: 2025-3-23 14:05
Multipotent Embryonic Lung Progenitors: Foundational Units of In Vitro and In Vivo Lung Organogenesi that allow for mechanistic studies of cell fate decisions and developmental processes. As our understanding of embryonic progenitor biology deepens, we move closer to the goal of in vitro lung organogenesis and resulting applications in developmental biology and medicine.作者: CHARM 時(shí)間: 2025-3-23 18:07
Computational, Ex Vivo, and Tissue Engineering Techniques for Modeling Large Airwaysm both a basic physiology perspective and an engineering perspective for regenerative medicine. In this chapter, we will cover the large airways from an engineering perspective to highlight existing models of the large airways as well as future directions for modeling and repair.作者: AVOID 時(shí)間: 2025-3-24 00:26 作者: 休閑 時(shí)間: 2025-3-24 04:25 作者: lobster 時(shí)間: 2025-3-24 10:27
Assessment of Collagen in Translational Models of Lung Research In this chapter, we provide a comprehensive overview on the various methodologies currently available for quantification and characterization of collagen including their detection principles, advantages, and disadvantages.作者: Aboveboard 時(shí)間: 2025-3-24 14:37 作者: Mumble 時(shí)間: 2025-3-24 17:17
,Ayn Rand’s Ethics of Rational Selfishness,ung, (2) the large airways, (3) the mesenchyme and parenchyma, (4) the pulmonary vasculature, and (5) the interface between lungs and medical devices. Each section highlights the underlying premise that engineering strategies, when applied in collaboration with cell biologists and pulmonary physicia作者: 榨取 時(shí)間: 2025-3-24 22:43
submucosal gland epithelium, extracellular matrix, and niche cells, including smooth muscle cells, fibroblasts, and immune cells. This chapter focuses on the structure-function relationships in the airways and the challenges of developing complex engineered models of the human airway.作者: 國家明智 時(shí)間: 2025-3-25 01:10 作者: 排出 時(shí)間: 2025-3-25 05:42
Bernard John,George L. Gabor Miklosiological processes to be mimicked. Lung-on-a-chip technologies also provide the possibility of obtaining biological information that was not possible with conventional in vitro systems. Pulmonary edema leaking through a damaged alveolar barrier and barrier stiffening due to excessive accumulation o作者: 憤怒歷史 時(shí)間: 2025-3-25 10:45
The Eurasian Vector of Russia’s Development developments in 3D biomaterial fabrication are enabling construction of vascularized tissues and microdevices with organotypic features at high resolution?to recapitulate the air-blood interface. In parallel, whole-lung decellularization produces biomaterial scaffolds with naturally occurring, acel作者: AUGUR 時(shí)間: 2025-3-25 11:58 作者: 分開 時(shí)間: 2025-3-25 18:14 作者: abject 時(shí)間: 2025-3-25 21:42
Basic Science Perspective on Engineering and Modeling the Large Airways submucosal gland epithelium, extracellular matrix, and niche cells, including smooth muscle cells, fibroblasts, and immune cells. This chapter focuses on the structure-function relationships in the airways and the challenges of developing complex engineered models of the human airway.作者: aesthetic 時(shí)間: 2025-3-26 01:08 作者: Assault 時(shí)間: 2025-3-26 04:26 作者: anniversary 時(shí)間: 2025-3-26 08:57 作者: 微生物 時(shí)間: 2025-3-26 13:41 作者: exigent 時(shí)間: 2025-3-26 20:51
Book 2023s against a variety of common pathologies. Current translational challenges arehighlighted, as are engineering opportunities to overcome these barriers.?This foundational text holds valuable lessons for researchers and clinicians throughout the fields of engineering, materials science, cell biology,作者: 悲痛 時(shí)間: 2025-3-26 23:47 作者: 割公牛膨脹 時(shí)間: 2025-3-27 01:24
An Introduction to Engineering and Modeling the Lung,uencing, induced pluripotent stem cell (iPSC) reprogramming, and 3D cell and tissue culture. Despite rigorous research and tireless efforts, chronic pulmonary diseases remain the third leading cause of death globally, with transplantation being the only option for treating end-stage disease. This ch作者: incontinence 時(shí)間: 2025-3-27 07:29
Simple Models of Lung Developmentments for lung diseases. A wide variety of rodent and human models are available that recapitulate one or more stages of lung development. This chapter describes the existing ‘simple’ in vitro, in silico and ex vivo models of lung development. We define which stage(s) of development each model recap作者: genesis 時(shí)間: 2025-3-27 13:17 作者: 諷刺 時(shí)間: 2025-3-27 16:08
Multipotent Embryonic Lung Progenitors: Foundational Units of In Vitro and In Vivo Lung Organogenesipment, multipotent mesenchymal and epithelial progenitors drive the diversification of fates that results to the plethora of cell types that compose the airways and alveolar space of the adult lungs. Use of mouse genetic models, including lineage tracing and loss-of-function studies, has elucidated 作者: bisphosphonate 時(shí)間: 2025-3-27 21:39 作者: 串通 時(shí)間: 2025-3-28 00:14
Computational, Ex Vivo, and Tissue Engineering Techniques for Modeling Large Airways physiological role of the large airways is to move a large amount of air to and from the gas exchange surfaces of the alveoli. This air becomes divided along the respiratory tree as it moves from the large airways to smaller airways, bronchioles, and alveoli. The large airways are incredibly import作者: Mercantile 時(shí)間: 2025-3-28 03:20 作者: SPALL 時(shí)間: 2025-3-28 09:54
Engineering and Modeling the Lung Mesenchymelized cells in the lung mesenchyme produce the extracellular matrix (ECM) and growth factors required for lung structure. Historically, characterizing the mesenchymal cell subtypes was challenging due to their ambiguous morphology, overlapping expression of protein markers, and limited cell-surface 作者: FILLY 時(shí)間: 2025-3-28 12:42 作者: 值得贊賞 時(shí)間: 2025-3-28 17:44 作者: 考古學(xué) 時(shí)間: 2025-3-28 21:47
Assessment of Collagen in Translational Models of Lung Research establishment of in vitro and organotypic models of lung disease, and as scaffold material of general interest for the field of lung bioengineering. Collagen also is the main readout for fibrotic lung disease, where collagen composition and molecular properties are drastically changed and ultimatel作者: 共和國 時(shí)間: 2025-3-29 02:12
Understanding and Engineering the Pulmonary Vasculature vascular endothelial cells, which exhibit tissue-specific phenotypes in term of their molecular signature, morphology, and function. The pulmonary microvascular endothelium is continuous and non-fenestrae to ensure stringent barrier function while allowing efficient gas exchange across the alveoli-作者: deviate 時(shí)間: 2025-3-29 06:29 作者: 無瑕疵 時(shí)間: 2025-3-29 10:59
Clinical Translation of Engineered Pulmonary Vascular Modelserstand lung vasculature during diseases and development. However, these systems are typically limited in their ability to represent human pathophysiology for the study of disease and drug mechanisms. In recent years, a growing number of studies have focused on developing in vitro experimental platf作者: 追蹤 時(shí)間: 2025-3-29 14:07
https://doi.org/10.1007/978-3-031-26625-6Bioengineering; Biomedical engineering; Pulmonary engineering; Lung tissue engineering; Lung bioengineer作者: dainty 時(shí)間: 2025-3-29 17:33
978-3-031-26627-0The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: GREEN 時(shí)間: 2025-3-29 22:18 作者: 透明 時(shí)間: 2025-3-30 00:57 作者: promote 時(shí)間: 2025-3-30 04:44 作者: Matrimony 時(shí)間: 2025-3-30 10:36
https://doi.org/10.1057/978-1-137-59445-72]. Whereas traditional reductionist approaches to in vitro models enable teasing apart the precise signaling pathways, cellular interactions, and response to biochemical and biophysical cues, model systems that incorporate higher complexity are needed to ask questions about physiology and morphogen作者: HEPA-filter 時(shí)間: 2025-3-30 15:03
Erich H. Loewy,Roberta Springer Loewypment, multipotent mesenchymal and epithelial progenitors drive the diversification of fates that results to the plethora of cell types that compose the airways and alveolar space of the adult lungs. Use of mouse genetic models, including lineage tracing and loss-of-function studies, has elucidated 作者: Abominate 時(shí)間: 2025-3-30 19:34 作者: 搖曳 時(shí)間: 2025-3-30 23:06