標(biāo)題: Titlebook: Endotoxins: Structure, Function and Recognition; Xiaoyuan Wang,Peter J. Quinn Book 2010 Springer Science+Business Media B.V. 2010 Antigen. [打印本頁] 作者: tornado 時間: 2025-3-21 16:06
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作者: grovel 時間: 2025-3-21 23:50 作者: BLAZE 時間: 2025-3-22 04:25 作者: 打折 時間: 2025-3-22 04:46
Targeting Endotoxin in the Treatment of Sepsisn Japan. Since both pre-clinical rationale and studies support the targeting of endotoxin to ameliorate the pro-inflammatory and pro-coagulation response of severe sepsis, this therapeutic intervention is being pursued.作者: 帶來 時間: 2025-3-22 09:24 作者: Flustered 時間: 2025-3-22 15:22 作者: Flustered 時間: 2025-3-22 20:41 作者: 鳴叫 時間: 2025-3-23 00:26
Lipopolysaccharides and Plant Innate Immunityr other MAMPs such as flagellin have been described. Recent work has implicated the . syntaxin PEN1 as a potential actor in LPS induction of plant defenses, which may suggest a role for vesicle trafficking in the signalling process.作者: quiet-sleep 時間: 2025-3-23 02:41
Book 2010e form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.This book brings together contributions from researchers in the forefront作者: 持久 時間: 2025-3-23 06:46
0306-0225 ording to their biosynthesis, genetic constitution, structurEndotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. En作者: 踉蹌 時間: 2025-3-23 11:50 作者: 音樂戲劇 時間: 2025-3-23 16:55
Synthetic and Natural TLR4 Agonists as Safe and Effective Vaccine Adjuvantsated the mechanism of action of TLR4 agonists and structure-function relationships. Moreover, the formulation of TLR4 agonists has been shown to significantly affect the type and magnitude of elicited immune response. TLR4 agonists comprise a promising class of adjuvants for safe and effective vaccines.作者: Biguanides 時間: 2025-3-23 18:21 作者: 鳥籠 時間: 2025-3-24 01:57
Purification and Characterization of Lipopolysaccharides O-antigen repeats. Lipid A is responsible for the major bioactivity of endotoxin. Because of their specific structure and amphipathic property, purification and analysis of lipopolysaccharides are difficult. In this chapter, we summarize the available approaches for extraction, purification and analysis of lipopolysaccharides.作者: 古代 時間: 2025-3-24 05:58 作者: Grandstand 時間: 2025-3-24 08:48
,Kapitel 2 (… 1884–1940/2000 …),ll surface and, therefore, structural modifications to the lipopolysaccharide (LPS). In this chapter, we describe the structures of the LPSs from symbiont members of the ., the genetics and mechanism of their biosynthesis, the modifications that occur during symbiosis, and their possible functions.作者: AVERT 時間: 2025-3-24 14:21 作者: overwrought 時間: 2025-3-24 16:03 作者: biopsy 時間: 2025-3-24 21:12 作者: Mnemonics 時間: 2025-3-25 02:06
The Diversity of the Core Oligosaccharide in Lipopolysaccharidesooligosaccharide with less than fifteen sugars, more conserved in the inner region, proximal to the lipid A, and often carrying non-stoichiometric substitutions leading to variation and micro-heterogeneity. The core oligosaccharide contributes to the bacterial viability and stability of the outer me作者: 和諧 時間: 2025-3-25 06:12
,-Regulated Lipopolysaccharide Modifications often regulate their virulence genes, including those responsible for lipopolysaccharide modification, in ways that differ from .. Further examination of bacterial virulence gene regulation and lipopolysaccharide modifications may lead to improved antimicrobial therapies and vaccines.作者: 不連貫 時間: 2025-3-25 09:50
Membrane Partitioning: Is Location Everything When It Comes to Endotoxin Recognition?ducer singals that lead to innate immune activation. In this chapter will review all past and current literature concerning recruitment of TLRs into lipid rafts and how this membrane compartmentalization is crucial for innate immune responses.作者: bonnet 時間: 2025-3-25 12:57
Endotoxin Detection – from , Amebocyte Lysate to Recombinant Factor Ce end of the reaction. The Factor C, which normally exists as a zymogen, is the primer of this coagulation cascade. In vivo, Factor C is the perfect biosensor, which alerts the horseshoe crab of the presence of a Gram-negative invader. The hemostatic end-point entraps the invader, killing it and lim作者: Entreaty 時間: 2025-3-25 17:43
The Role of Endotoxin in Infection: , and ,er hand, this contrasts with acute infection-causing . where overt inflammation contributes to pathology and diarrhoea production, and whose endotoxin is immunologically and endotoxically active. Futhermore, both . and . exhibit molecular mimicry in the saccharide components of their endotoxins whic作者: 體貼 時間: 2025-3-25 22:32 作者: ingestion 時間: 2025-3-26 02:11 作者: Hypopnea 時間: 2025-3-26 04:47 作者: 規(guī)范要多 時間: 2025-3-26 10:35 作者: 周年紀(jì)念日 時間: 2025-3-26 13:58
https://doi.org/10.1007/978-3-662-64949-7ooligosaccharide with less than fifteen sugars, more conserved in the inner region, proximal to the lipid A, and often carrying non-stoichiometric substitutions leading to variation and micro-heterogeneity. The core oligosaccharide contributes to the bacterial viability and stability of the outer me作者: Priapism 時間: 2025-3-26 16:54
https://doi.org/10.1007/978-3-662-69504-3 often regulate their virulence genes, including those responsible for lipopolysaccharide modification, in ways that differ from .. Further examination of bacterial virulence gene regulation and lipopolysaccharide modifications may lead to improved antimicrobial therapies and vaccines.作者: Exuberance 時間: 2025-3-27 00:27 作者: TERRA 時間: 2025-3-27 01:22
Aufbereitung des Datenmaterials,e end of the reaction. The Factor C, which normally exists as a zymogen, is the primer of this coagulation cascade. In vivo, Factor C is the perfect biosensor, which alerts the horseshoe crab of the presence of a Gram-negative invader. The hemostatic end-point entraps the invader, killing it and lim作者: 說笑 時間: 2025-3-27 07:26
https://doi.org/10.1007/978-3-662-70041-9er hand, this contrasts with acute infection-causing . where overt inflammation contributes to pathology and diarrhoea production, and whose endotoxin is immunologically and endotoxically active. Futhermore, both . and . exhibit molecular mimicry in the saccharide components of their endotoxins whic作者: 全能 時間: 2025-3-27 10:45 作者: 自傳 時間: 2025-3-27 15:43
https://doi.org/10.1007/978-3-662-65830-7ign non-peptidic, nontoxic, small-molecule LPS-sequestrants. Our efforts began with defining the central pharmacophore that determined LPS-recognition and -neutralization properties in small molecules, which led to the discovery of a novel lipopolyamine lead, DS-96. DS-96 is an effective LPS-neutral作者: 瘙癢 時間: 2025-3-27 21:09 作者: 包租車船 時間: 2025-3-27 23:26 作者: GLOOM 時間: 2025-3-28 02:44
Purification and Characterization of Lipopolysaccharideslecule. They can cause severe diseases like sepsis and therefore known as endotoxins. Lipopolysaccharide consists of lipid A, core oligosaccharide and O-antigen repeats. Lipid A is responsible for the major bioactivity of endotoxin. Because of their specific structure and amphipathic property, purif作者: 煩憂 時間: 2025-3-28 09:51 作者: Hot-Flash 時間: 2025-3-28 11:19
The Diversity of the Core Oligosaccharide in Lipopolysaccharidesontribute to the cellular rigidity by increasing the strength of cell wall and mediating contacts with the external environment that can induce structural changes to allow life in different conditions. Furthermore, the low permeability of the outer membrane acts as a barrier to protect bacteria from作者: 緊張過度 時間: 2025-3-28 15:06
,-Regulated Lipopolysaccharide Modificationsades such as two-component regulatory systems to detect and respond to stimuli in the local microenvironment. During infection, environmental sensing allows bacteria to regulate gene expression to evade host immune defenses and thrive in vivo. Activation of the . two-component regulatory systems Pho作者: Hectic 時間: 2025-3-28 20:53
The Variation of O Antigens in Gram-Negative Bacteriaacteria. It is on the cell surface and appears to be a major target for both immune system and bacteriophages, and therefore becomes one of the most variable cell constituents. The variability of the O antigen provides the major basis for serotyping schemes of Gram-negative bacteria. The genes respo作者: GLUE 時間: 2025-3-28 22:53
Regulators of TLR4 Signaling by Endotoxinser the past decade have revealed the components involved in these signaling pathways, however, more recently the focus has shifted somewhat towards the components that regulate these pathways. Several regulatory mechanisms, including localisation of components, splice variants and inhibitory molecul作者: 鼓掌 時間: 2025-3-29 05:30
Membrane Partitioning: Is Location Everything When It Comes to Endotoxin Recognition? Lipid rafts are thought to provide a means to explain the spatial segregation of certain signalling pathways emanating from the cell surface. They seem to provide the necessary microenvironment in order for certain specialised signalling events to take place- such as the innate immune recognition. 作者: 付出 時間: 2025-3-29 11:07 作者: Limousine 時間: 2025-3-29 11:27
The Role of Endotoxin in Infection: , and ,l compartment and . the intestinal mucosa. Although . causes chronic gastric infection leading to gastritis, peptic ulcers and eventually gastric cancer while . causes acute infection inducing diarrhoeal disease, the endotoxin molecules of both bacterial species contrastingly contribute to their pat作者: 增減字母法 時間: 2025-3-29 16:13
The Role of , Lipopolysaccharide in Cystic Fibrosis Airway Infectionwith impaired phagocytic function, such as those with burns, exposure to chemotherapy, or cystic fibrosis (CF). PA infects the lungs of most individuals with CF, and is associated with severe progressive pulmonary disease that is the major cause of premature death in this disorder. The specific adap作者: 反叛者 時間: 2025-3-29 23:44
Development of Small-Molecule Endotoxin Sequestering Agentspite advances in antimicrobial chemotherapy. The primary trigger in Gram-negative sepsis is endotoxin, a lipopolysaccharide (LPS) constituent of the outer membrane of all Gram-negative bacteria. The structurally highly conserved glycolipid called lipid A is the active moiety of LPS. Lipid A is compo作者: 向外供接觸 時間: 2025-3-30 00:42
Development of an Anti-Endotoxin Vaccine for Sepsisin intensive care units. Vaccines directed against core LPS structures that are widely conserved among Gram-negative bacteria (GNB) have been developed for the treatment and/or prevention of sepsis. Killed whole bacterial vaccines (. O111:B4, J5 [Rc chemotype] mutant and ., Re chemotype) protected m作者: Alveolar-Bone 時間: 2025-3-30 06:20 作者: 我們的面粉 時間: 2025-3-30 12:15
Targeting Endotoxin in the Treatment of Sepsiscan be bound by antibodies (whose role as a therapeutic agent is unlikely), binding proteins such as BPI or human lactoferrin (effectiveness debated and promising respectively) and phospholipid emulsion (which has not improved outcomes in a recent study). Alternatively, the action of endotoxin could作者: 過于平凡 時間: 2025-3-30 15:32
Lipopolysaccharides in ,-Legume Symbiosesons that occur with the host plant that both promotes and allows infection of the host root nodule cell, regulates and resists the host defense response, permits the exchange of metabolites, and contributes to the overall health of the host. This adaptive process involves changes to the bacterial ce作者: 提名的名單 時間: 2025-3-30 16:37
Lipopolysaccharides and Plant Innate Immunity Microbe Associated Molecular Patterns (MAMPs) act to trigger basal defense responses in plants. These elicitors include lipopolysaccharides (LPS) from diverse Gram-negative bacteria. Both core oligosaccharide and the lipid A moieties of LPS as well as synthetic O-antigen oligosaccharides have activ作者: Slit-Lamp 時間: 2025-3-30 21:25
https://doi.org/10.1007/978-90-481-9078-2Antigen; Sepsis; bacteria; infection; infectious; vaccine; infectious diseases作者: Forehead-Lift 時間: 2025-3-31 04:08 作者: Blazon 時間: 2025-3-31 07:43 作者: 悄悄移動 時間: 2025-3-31 10:55
Anwendungen und Anwendbarkeit des Modells,elease from bacterial cells. Thus, the characterization of the physicochemical properties of this glycolipid in physiological fluids is of utmost importance for an understanding of cell activation processes. Here, the essential physicochemical parameters describing endotoxins such as critical micell作者: 疾馳 時間: 2025-3-31 16:51
https://doi.org/10.1007/978-3-662-64949-7ontribute to the cellular rigidity by increasing the strength of cell wall and mediating contacts with the external environment that can induce structural changes to allow life in different conditions. Furthermore, the low permeability of the outer membrane acts as a barrier to protect bacteria from作者: Humble 時間: 2025-3-31 20:31 作者: Exploit 時間: 2025-3-31 22:01 作者: Bronchial-Tubes 時間: 2025-4-1 03:44
,Sch?tzung nach Heilbronner Sortirung,er the past decade have revealed the components involved in these signaling pathways, however, more recently the focus has shifted somewhat towards the components that regulate these pathways. Several regulatory mechanisms, including localisation of components, splice variants and inhibitory molecul作者: 招待 時間: 2025-4-1 09:47
Musikalische Praxis und Aufführungslehre Lipid rafts are thought to provide a means to explain the spatial segregation of certain signalling pathways emanating from the cell surface. They seem to provide the necessary microenvironment in order for certain specialised signalling events to take place- such as the innate immune recognition.