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標(biāo)題: Titlebook: Endothelin; Molecular Biology, P Robert F. Highsmith Book 1998 Springer Science+Business Media New York 1998 cardiovascular.endothelium.enz [打印本頁]

作者: 女性    時(shí)間: 2025-3-21 18:20
書目名稱Endothelin影響因子(影響力)




書目名稱Endothelin影響因子(影響力)學(xué)科排名




書目名稱Endothelin網(wǎng)絡(luò)公開度




書目名稱Endothelin網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Endothelin被引頻次




書目名稱Endothelin被引頻次學(xué)科排名




書目名稱Endothelin年度引用




書目名稱Endothelin年度引用學(xué)科排名




書目名稱Endothelin讀者反饋




書目名稱Endothelin讀者反饋學(xué)科排名





作者: 破裂    時(shí)間: 2025-3-21 22:49
Molecular Biology of the Endothelin Receptors,ion of the molecular details of the endothelin (ET) system has progressed rapidly via a multidisciplinary approach using the tools of biochemistry, chemistry, pharmacology, and molecular biology. Milestones in the development of this area include the isolation . and three-dimensional structure deter
作者: 軍火    時(shí)間: 2025-3-22 00:40
Molecular Biology of Endothelin-Converting Enzyme (ECE),onsisting of 21 amino-acid residues, is generated from an inactive form of big ET-1 by a specific enzyme, called endothelin-converting enzyme (ECE). Accelerated production of ET-1 in damaged vascular endothelial cells was strongly suggested to be involved in the development of various fatal cardiova
作者: Gingivitis    時(shí)間: 2025-3-22 05:57
Endothelin Receptor-Signaling Mechanisms in Vascular Smooth Muscle,most lining of all blood vessels. By virtue of its location at the blood—tissue interface in vivo, vascular endothelium is ideally suited to play a pivotal role in vascular tone regulation. It is now well-documented that endothelial cells produce several vasoactive substances that activate or inhibi
作者: LIKEN    時(shí)間: 2025-3-22 10:11

作者: 是貪求    時(shí)間: 2025-3-22 15:56
The Renal and Systemic Hemodynamic Actions of Endothelin,elial cell constricting factor (EDCF) by Hickey et al. in 1985 . and the subsequent cloning of endothelin-1 (ET-1) by Yanagisawa et al., in 1988 .. Endothelin and endothelinrelated peptides (ET-1, ET-2, and ET-3) have profound effects on a number of hemodynamic variables relating to cardiovascular a
作者: 是貪求    時(shí)間: 2025-3-22 17:50
The Development of Specific Endothelin-Receptor Antagonists,em, where they are potent vasoconstrictors and pressor agents, although there may also be accompanying vasodilatation, particularly at low concentrations .,.. The ETs also have numerous other effects, such as stimulating the release of autacoids and hormones, contracting nonvascular smooth muscle, p
作者: HAIRY    時(shí)間: 2025-3-22 22:12

作者: 群居男女    時(shí)間: 2025-3-23 02:48
European Values in the New Global Contextses that transduce signals from cell surface receptors to the nucleus, thus altering the transcription of genes which lead to the mitogenic response. In this chapter I will first explore the role of the ETs as growth factors and discuss candidate modulators or transducers of the mitogenic signal. Th
作者: 蒼白    時(shí)間: 2025-3-23 06:07

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作者: bile648    時(shí)間: 2025-3-24 01:40

作者: 殘暴    時(shí)間: 2025-3-24 06:00
Why the transatlantic economy still mattersonsisting of 21 amino-acid residues, is generated from an inactive form of big ET-1 by a specific enzyme, called endothelin-converting enzyme (ECE). Accelerated production of ET-1 in damaged vascular endothelial cells was strongly suggested to be involved in the development of various fatal cardiova
作者: 倔強(qiáng)一點(diǎn)    時(shí)間: 2025-3-24 10:33

作者: 冬眠    時(shí)間: 2025-3-24 12:31
European Values in the New Global Contexttor activated pathways. The most proximal mechanisms activated by ETs are well known—activation of phospholipase C-β, and subsequently protein kinase C (PKC), and activation of plasma membrane Ca. channels. What is only starting to become clear is how these proximal signaling pathways, which are str
作者: 解決    時(shí)間: 2025-3-24 16:43
elial cell constricting factor (EDCF) by Hickey et al. in 1985 . and the subsequent cloning of endothelin-1 (ET-1) by Yanagisawa et al., in 1988 .. Endothelin and endothelinrelated peptides (ET-1, ET-2, and ET-3) have profound effects on a number of hemodynamic variables relating to cardiovascular a
作者: Cervical-Spine    時(shí)間: 2025-3-24 22:00
Zur Musik?sthetik Robert Schumannsem, where they are potent vasoconstrictors and pressor agents, although there may also be accompanying vasodilatation, particularly at low concentrations .,.. The ETs also have numerous other effects, such as stimulating the release of autacoids and hormones, contracting nonvascular smooth muscle, p
作者: BROTH    時(shí)間: 2025-3-25 00:39
Uwe Cantner,Jean-Luc Gaffard,Lionel Nestain, its receptors, and their potential role in physiological and pathophysiological processes. There is an ever-increasing literature describing the importance of endothelin and the potential use of ET-receptor antagonists in a number of diverse diseases (Table 1). A detailed description of the evid
作者: Calibrate    時(shí)間: 2025-3-25 06:10
https://doi.org/10.1007/978-1-4757-2783-8cardiovascular; endothelium; enzymes; physiology; smooth muscle; tissue
作者: 使成波狀    時(shí)間: 2025-3-25 07:54

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作者: chronology    時(shí)間: 2025-3-25 16:46

作者: 畢業(yè)典禮    時(shí)間: 2025-3-25 21:07
Endothelin Receptor Subtypes and Tissue Distribution,al cell biology has rapidly expanded into a distinct discipline. Numerous endothelial-derived factors have been identified as important contributors in the regulation of vascular tone, including relaxing or contracting substances, such as prostacyclin, nitric oxide, and endothelin.
作者: intoxicate    時(shí)間: 2025-3-26 03:34
Book 1998l, and industrial researchers summarize the dramatic recent progress in endothelin research and indicate the optimal direction of future studies. The contributors produce a critical evaluation ofendothelin chemistry and pharmacology, its mechanism of action, and its physiological functions. The book
作者: 珊瑚    時(shí)間: 2025-3-26 05:12

作者: Custodian    時(shí)間: 2025-3-26 09:57
Zur Musik?sthetik Robert Schumannsardiovascular system, and the production of ET-receptor antagonists has principally been aimed at generating compounds that will reduce the deleterious effects of the endothelins in vascular pathologies ranging from hypertension to renal failure and stroke.
作者: Freeze    時(shí)間: 2025-3-26 14:45
The Renal and Systemic Hemodynamic Actions of Endothelin, of magnitude. In addition, a number of studies have demonstrated that ET-1 possesses significant vasodilator properties, demonstrating that the molecule has rather unique properties among the long list of vasoactive, biologically important molecules.
作者: palpitate    時(shí)間: 2025-3-26 17:51
The Development of Specific Endothelin-Receptor Antagonists,ardiovascular system, and the production of ET-receptor antagonists has principally been aimed at generating compounds that will reduce the deleterious effects of the endothelins in vascular pathologies ranging from hypertension to renal failure and stroke.
作者: assail    時(shí)間: 2025-3-27 00:02
c, clinical, and industrial researchers summarize the dramatic recent progress in endothelin research and indicate the optimal direction of future studies. The contributors produce a critical evaluation ofendothelin chemistry and pharmacology, its mechanism of action, and its physiological functions
作者: BLANC    時(shí)間: 2025-3-27 04:11
Book 1998 is certain to become the new standard reference source for both basic scientists and informed clinicians who want a clear idea of the roles endothelin may play in cardiovascular physiology and pathology. ....
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作者: 震驚    時(shí)間: 2025-3-27 23:03
Molecular Biology of the Endothelin Receptors,e development of potent peptide and nonpeptide antagonists ., and, more recently, the disruption of the genes encoding ET-1, ET-3, and the ET. receptor subtype .. Thus elucidation of the intricacies of the endothelin system has been the product of a truly molecular approach to pharmacology.
作者: 婚姻生活    時(shí)間: 2025-3-28 05:57
Molecular Biology of Endothelin-Converting Enzyme (ECE),of ECE, along with those of ET receptors, may lead to the development of new treatments for these diseases. Accordingly, many investigators have focused on the identification and characterization of ECE. This chapter describes a history from the discovery of ECE to molecular characterization of this enzyme.
作者: 抒情短詩    時(shí)間: 2025-3-28 06:41
Endothelin Receptor-Signaling Mechanisms in Vascular Smooth Muscle, of biochemical and morphological events that are responsible directly for mediating changes in vessel diameter. To date, endothelin is one of the most potent stimulators of both vascular and nonvascular smooth muscle contraction that has been identified.
作者: Abutment    時(shí)間: 2025-3-28 10:57
Sarah Barnssowie als Kompetenzziel in der polizeilichen Bildung. Eine M?glichkeit zur F?rderung dieser Kompetenz sowie zur Ausbildung der F?higkeit demokratisch ausgerichteter Urteils- und Entscheidungsfindung besteht im Aufbau eines professionellen Verst?ndnisses von Empathie..978-3-658-45113-4978-3-658-45114-1Series ISSN 2662-9445 Series E-ISSN 2662-9453
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作者: beta-carotene    時(shí)間: 2025-3-29 09:01
https://doi.org/10.1007/978-3-642-74327-6ow professionals and the public. IDEAL is an example of how compelling science can be accomplished without inflated budgets, grandiose administrative schemes, or competing egos. As such, it presents an instructive case study about the ontogeny of a scientific initiative.




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