標(biāo)題: Titlebook: Endorphins and Opiate Antagonists in Psychiatric Research; Clinical Implication Nandkumar S. Shah (Chief of Research Services, Res Book 198 [打印本頁(yè)] 作者: amateur 時(shí)間: 2025-3-21 17:14
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作者: COKE 時(shí)間: 2025-3-22 00:09 作者: RAG 時(shí)間: 2025-3-22 04:13 作者: 違反 時(shí)間: 2025-3-22 05:19
Dialysis of Schizophrenia,Schizophrenia is probably the greatest health problem facing the world today. This is true because it is a common illness, which beginning early in adulthood usually afflicts and incapacitates the sufferer throughout life and is an illness for which no really satisfactory treatment has been found.作者: PET-scan 時(shí)間: 2025-3-22 09:28 作者: Sad570 時(shí)間: 2025-3-22 15:26 作者: Sad570 時(shí)間: 2025-3-22 19:10 作者: Lobotomy 時(shí)間: 2025-3-22 23:27 作者: 青少年 時(shí)間: 2025-3-23 02:07
Greatness, Identity, and Method, of the opium poppy (.) were known to the ancient Sumerians (ca. 4000 B.C.) and were noted in the Eber papyrus, an Egyptian hieroglyphic document (ca. 1550 B.C.). Of the more than 20 alkaloids contained in opium, morphine, which was first isolated by Sertürner in 1803, is the most important constitu作者: Flu表流動(dòng) 時(shí)間: 2025-3-23 06:39 作者: 同音 時(shí)間: 2025-3-23 12:13 作者: 煩擾 時(shí)間: 2025-3-23 15:24
The Role of Household Plots in Rural Areases. There appear to be several types of receptor and four main varieties have so far been claimed, κ, σ, δ, and μ (Martin .., 1976; Lord .., 1977). Relatively little attention has as yet been paid to what happens after receptor activation. It is usually assumed, although often not explicitly stated,作者: helper-T-cells 時(shí)間: 2025-3-23 21:04
Ryan C. Maness,Brandon Valerianond/or neurotransmitters in the brain (Frederickson, 1977; Dupont .., 1980; Hersh .., 1980; Osborne and Herz, 1980; Wamsley ..,1980). They are localized in nerve terminals and cell bodies of neurons and show marked regional variations in concentration in the CNS (Hong .., 1977; Emson .., 1980). Resul作者: intoxicate 時(shí)間: 2025-3-23 22:20
Russia’s Domestic Security Warst-enkephalin: H-Tyr-Gly-Gly-Phe-Met-OH; Leu-enkephalin: H-Tyr-Gly-Gly-Phe-Leu-OH) were isolated from porcine (Bradbury .., 1976) and calf (Simantov and Snyder, 1976) brain and shown to possess high opiate agonist activity. The sequence of Met-enkephalin is the same as the N-terminus of β-endorphin, 作者: HEDGE 時(shí)間: 2025-3-24 04:08 作者: 不能平靜 時(shí)間: 2025-3-24 06:57 作者: FILTH 時(shí)間: 2025-3-24 12:45
Russia‘s Oil Barons and Metal Magnates Hughes (1975) isolated the endogenous ligands. The important ligands are the two pentapeptides Met- and Leu-enkephalin (Hughes ..,1975) as well as β-endorphin (β-lipotropin.). There is overwhelming evidence that the glycoprotein pro-opiocortin is the parent substance for both adrenocorticotropic ho作者: Folklore 時(shí)間: 2025-3-24 15:15
Russia’s Relations with the GCC and Iranm, and other processes of importance in the maintenance of homeostasis. The release of anterior pituitary hormones is controlled by both releasing and release-inhibiting factors, produced in the hypothalamus and transported to the pituitary gland via the bloodstream (portal vascular system between h作者: corn732 時(shí)間: 2025-3-24 21:48
https://doi.org/10.1007/978-1-349-20654-4rogenic actions of opiates and endorphins (Kline ..,1977) in normal subjects and the antidepressive action of the synthetic analog of Met-enkephalin, FK 33–824, in psychotic patients (Nedopil and Rüther, 1979), which led to speculation that endogenous opioids may be responsible for mood changes in a作者: 紳士 時(shí)間: 2025-3-25 02:26 作者: Infantry 時(shí)間: 2025-3-25 05:13 作者: Ascribe 時(shí)間: 2025-3-25 09:58 作者: antenna 時(shí)間: 2025-3-25 13:10
,Allgemeines – Общая информация, various psychiatric disorders. It is but natural to link a newly discovered naturally occurring substance to the disease states, particularly when the substance seems to have related physiological functions. Hence, abnormalities in its disposition can obviously be implicated in these diseases. In r作者: anchor 時(shí)間: 2025-3-25 16:21 作者: beta-carotene 時(shí)間: 2025-3-25 21:36
https://doi.org/10.1007/978-3-662-62044-1of phenylketonuric patients (Folling, 1934), This approach has proved to be extremely productive in identifying biochemical markers, predicting enzymatic lesions, and finally pinpointing the genetic basis of a large number of metabolic diseases inherited in Mendelian fashion (Stanbury .., 1978). Alt作者: 名義上 時(shí)間: 2025-3-26 02:12 作者: chemoprevention 時(shí)間: 2025-3-26 06:38
,β-Endorphin and Central Nervous System,of the biologically most active opioids is β-endorphin, which, in the CNS, apparently is localized intraneuronally (Bloom ..,1978; Watson ..,1978) and has been implicated as a putative neurotransmitter, neuromodulator or neurohormone (Bloom ..,1976; Gispen ..,1977; Nicoll ..,1977; Barchas ..,1978; Donovan, 1978; Kastin .., 1979; Riley .., 1980).作者: 天賦 時(shí)間: 2025-3-26 11:24
Endorphins in Psychiatric Research and Treatment, release-inhibiting factors, produced in the hypothalamus and transported to the pituitary gland via the bloodstream (portal vascular system between hypothalamus and pituitary gland). Neurohypophyseal hormones produced in the hypothalamus are transported via neurons to the posterior pituitary lobe where they are stored.作者: Diastole 時(shí)間: 2025-3-26 16:29
Ryan C. Maness,Brandon Valerianots of a number of recent studies have suggested a close relationship between enkephalinergic and dopaminergic neurons, and also a possible role of the endogenous opiate peptides in the pathogenesis of some mental disorders (Jacquet and Marks, 1976; Frederickson, 1977; Verebey .., 1978; Watson .., 1979; Bowers, 1980).作者: 透明 時(shí)間: 2025-3-26 18:40 作者: BULLY 時(shí)間: 2025-3-27 00:36
The Role of Household Plots in Rural Areaslatively little attention has as yet been paid to what happens after receptor activation. It is usually assumed, although often not explicitly stated, that this activation involves modulation of ion fluxes across the membrane. However, some work suggests that cyclic AMP and prostaglandins may also be involved at the second-messenger level.作者: canvass 時(shí)間: 2025-3-27 04:07
Russia‘s Encounter with Globalisationof the biologically most active opioids is β-endorphin, which, in the CNS, apparently is localized intraneuronally (Bloom ..,1978; Watson ..,1978) and has been implicated as a putative neurotransmitter, neuromodulator or neurohormone (Bloom ..,1976; Gispen ..,1977; Nicoll ..,1977; Barchas ..,1978; Donovan, 1978; Kastin .., 1979; Riley .., 1980).作者: 音樂(lè)會(huì) 時(shí)間: 2025-3-27 05:36 作者: 致命 時(shí)間: 2025-3-27 12:54 作者: 外貌 時(shí)間: 2025-3-27 16:30
https://doi.org/10.1007/978-3-662-62044-1otein synthesis at crucial developmental times, and may have alterations of normal bone growth or pigmentation (Tourian and Sidbury, 1978). By analogy, any metabolic lesion that leads to psychosis as its primary symptom must be biochemically quite subtle, as most psychotic patients do not have overt physical findings or mental retardation.作者: 強(qiáng)制性 時(shí)間: 2025-3-27 19:50
Peptides and Amino Acids in Human Hemodialysate,otein synthesis at crucial developmental times, and may have alterations of normal bone growth or pigmentation (Tourian and Sidbury, 1978). By analogy, any metabolic lesion that leads to psychosis as its primary symptom must be biochemically quite subtle, as most psychotic patients do not have overt physical findings or mental retardation.作者: anaerobic 時(shí)間: 2025-3-28 01:32
https://doi.org/10.1007/978-1-4899-6860-9o acid sequences 61–76 and 61–77 of β-LPH, respectively, and β-endorphin (“C-fragment”) is identical to amino acid sequence 69–91 of β-LPH. All of these endorphins have tyrosine as the NH.-terminal amino acid, which could be considered crucial in exerting various physiological/pharmacological effects.作者: 難聽(tīng)的聲音 時(shí)間: 2025-3-28 02:24 作者: MAPLE 時(shí)間: 2025-3-28 09:54
Russia’s Domestic Security Warscamel pituitary glands (Li and Chung, 1976) as well as from many other species including the human, and shown to be an analgesic agent as measured by both . (Bradbury .., 1976; Cox .., 1976; Li and Chung, 1976) and . (Loh .., 1976) methods.作者: intrude 時(shí)間: 2025-3-28 12:22 作者: 外來(lái) 時(shí)間: 2025-3-28 14:48
Russisch - Deutsch für die Pflege zu Hauserapidly and completely absorbed with peak plasma levels of parent compound in 1 hr and of active metabolite (β-naltrexol) in 2 hr without accumulation (Verebey ., 1976). The use of naltrexone in schizophrenic patients was primarily an attempt to evaluate the role of endorphins and opiate cells in mental illness.作者: entail 時(shí)間: 2025-3-28 19:56 作者: maverick 時(shí)間: 2025-3-29 02:53
Central Nervous System Effects after Systemic Injection of Opiate Peptides,g comparable effects with systemic administration of the same peptides were not successful, however, with a resulting focus of interest on the use of central injections (e.g., Kosterlitz and Hughes, 1977).作者: 卡死偷電 時(shí)間: 2025-3-29 06:15 作者: 并排上下 時(shí)間: 2025-3-29 10:37
Biochemical Evidence for a Role for Endorphins in Mental Illness,. Such evidence as the behavioral responses induced by endorphin administration (Lehmann .., 1979) and the relationship of endorphin levels in the cerebrospinal fluid to psychiatric diagnoses (Rimon .., 1980) has led to the suggestion that endorphins may be linked to psychiatric disorders.作者: 羊齒 時(shí)間: 2025-3-29 15:28
The Use of an Oral Opiate Antagonist in Schizophrenia,rapidly and completely absorbed with peak plasma levels of parent compound in 1 hr and of active metabolite (β-naltrexol) in 2 hr without accumulation (Verebey ., 1976). The use of naltrexone in schizophrenic patients was primarily an attempt to evaluate the role of endorphins and opiate cells in mental illness.作者: BILIO 時(shí)間: 2025-3-29 19:22
Book 1982e molecular structure, moving to the understanding of the mecha- nisms mediating the synaptic action, and to the appraisal of the involve- ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule‘s role in brain function and the consequences that作者: 漸變 時(shí)間: 2025-3-29 20:02 作者: adipose-tissue 時(shí)間: 2025-3-30 02:28
Nandkumar S. Shah (Chief of Research Services, Res作者: Onerous 時(shí)間: 2025-3-30 05:34
Endorphins and Opiate Antagonists in Psychiatric Research978-1-4684-1119-5作者: 等級(jí)的上升 時(shí)間: 2025-3-30 09:43
Greatness, Identity, and Method, The exponential increase in the number of scientific reports in this field of research is an indication of the importance attached to this area of neurobiology. Two major breakthroughs, the discovery of opiate receptors in the CNS of animals and man and the ensuing discovery of endogenous opiate-li作者: hemophilia 時(shí)間: 2025-3-30 15:41
Anastasia Ponamareva,Sergey Ponamarev to define the mechanism(s) of opiate analgesia, with the hope that once the mechanism of pain inhibition is understood, such mechanism alone can be triggered to produce analgesia without causing undesirable effects.作者: TSH582 時(shí)間: 2025-3-30 17:56
Russia‘s Oil Barons and Metal Magnates contains a precursor polypeptide for enkephalins (Kimura ., 1980). Shine and colleagues (1980), by employing gene cloning techniques, have manipulated bacteria to produce β-endorphins. This will provide in the future enough β-endorphins for clinical evaluations as well as toxicity studies inexpensi作者: dissent 時(shí)間: 2025-3-30 22:39 作者: STALL 時(shí)間: 2025-3-31 04:52 作者: 有惡意 時(shí)間: 2025-3-31 06:44
https://doi.org/10.1007/978-1-349-62712-7effect of endorphins, based on alteration of conditioned avoidance behavior (de Wied .., 1978a) and production of catalepsy (Bloom .., 1976; Jacquet and Marks, 1976); and (4) the common exogenous opiate alkaloids (e.g., morphine, heroin) have psychoactive properties that include production of psycho作者: Vulnerary 時(shí)間: 2025-3-31 11:31
,Allgemeines – Общая информация,s yet unanswered questions. It is the intention of the author to evaluate briefly the role of opiate antagonists in various psychiatric illnesses and share the personal experiences in the subject matter.作者: Latency 時(shí)間: 2025-3-31 16:37
Book 1982ther transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to ab作者: 薄荷醇 時(shí)間: 2025-3-31 18:50
larly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to ab978-1-4684-1121-8978-1-4684-1119-5作者: Meditate 時(shí)間: 2025-4-1 00:06
The Opiate Receptor and Its Endogenous Ligands An Overview, The exponential increase in the number of scientific reports in this field of research is an indication of the importance attached to this area of neurobiology. Two major breakthroughs, the discovery of opiate receptors in the CNS of animals and man and the ensuing discovery of endogenous opiate-li
