標題: Titlebook: Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity; Akihiko Yoshimura Book 2017 The Editor(s) (if applicable) and T [打印本頁] 作者: Ejaculation 時間: 2025-3-21 19:55
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity影響因子(影響力)
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity影響因子(影響力)學科排名
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity網(wǎng)絡(luò)公開度
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity網(wǎng)絡(luò)公開度學科排名
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity被引頻次
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity被引頻次學科排名
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity年度引用
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity年度引用學科排名
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity讀者反饋
書目名稱Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity讀者反饋學科排名
作者: N防腐劑 時間: 2025-3-21 23:03 作者: 紀念 時間: 2025-3-22 03:21 作者: Hdl348 時間: 2025-3-22 04:41
Enrique Ballestero,Carlos RomeroT cells (IL-10-producing Treg cells) constitute a Treg cell subset characterized by the production of high amounts of IL-10, cytokine-mediated immunosuppressive capabilities, and independence of Foxp3 expression for their suppressive activity. In the past decade, identifying naturally occurring IL-1作者: Introvert 時間: 2025-3-22 12:00
https://doi.org/10.1007/978-3-642-70583-0ered to be essential antigen (Ag)-presenting cells (APCs) that play crucial roles in activation and fine-tuning of innate and adaptive immunity under inflammatory conditions, as well as induction of immune tolerance to maintain immune homeostasis under steady-state conditions. Furthermore, DC functi作者: panorama 時間: 2025-3-22 14:08 作者: panorama 時間: 2025-3-22 19:48 作者: figment 時間: 2025-3-22 21:51 作者: Ascribe 時間: 2025-3-23 02:36 作者: 拾落穗 時間: 2025-3-23 07:52
https://doi.org/10.1007/978-3-319-47759-6rity are present in immune cells and play various roles in either inhibiting or promoting the duration and amplitude of signaling cascades. Several PTPs, including TC-PTP (PTPN2) and SHP-1 (PTPN6), have been recognized as being crucial for maintaining proper immune response and self-tolerance, and h作者: 種屬關(guān)系 時間: 2025-3-23 13:37
Multiple Interest Rate Analysisfrom attacking its own tissues to maintain immune tolerance. The balance of activation and tolerance is tightly controlled by diverse mechanisms, since breakdown of tolerance could result in disastrous consequences such as the development of autoimmune diseases. One of the mechanisms is by the means作者: headway 時間: 2025-3-23 16:57
https://doi.org/10.1007/978-3-319-65425-6mmation and tissue damage. A wide range of molecular determinants and cellular components work in concert to control the magnitude and duration of a given immune response. In the past decade, microRNAs (miRNAs), a major class of small non-coding RNA species, have been extensively studied as key mole作者: flourish 時間: 2025-3-23 20:24
https://doi.org/10.1007/978-3-319-68929-6Anti-tumor immune response; Tumor immune microenvironment; Regulatory T cells; PD-1; Autoimmune disease; 作者: 退出可食用 時間: 2025-3-23 23:40
978-3-319-88684-8The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: FIN 時間: 2025-3-24 02:26 作者: 使害怕 時間: 2025-3-24 06:31
Regulatory T Cells: Molecular and Cellular Basis for Immunoregulationntegrate extracellular and intracellular signals to control their survival and stability. Deeper mechanistic understanding of disease-specific Treg development, maintenance, and function could make disease-specific Treg-targeted therapy more effective, resulting in an increase of efficacy and decrea作者: Compatriot 時間: 2025-3-24 12:47
Overview of LAG-3-Expressing, IL-10-Producing Regulatory T Cellsmanner. Moreover, the combined expression of LAG-3 and CD49b identifies IL-10-producing Treg cells in mice and humans more specifically. Recently, LAG-3 has gained more attention in the context of immune checkpoints because it believed to be related to T cell tolerance and exhausted T cells that inf作者: Manifest 時間: 2025-3-24 17:49 作者: intrigue 時間: 2025-3-24 20:15 作者: corn732 時間: 2025-3-25 02:17 作者: Ceremony 時間: 2025-3-25 05:07
SOCS1: Regulator of T Cells in Autoimmunity and Cancerdriven by inflammatory cytokines. In addition, SOCS1 is critical to maintain the stability of T regulatory cells and control their plasticity to become pathogenic Th17 and Th1 cells under the harmful influence of inflammatory cytokines. SOCS1 also regulates T cell activation by dendritic cells via m作者: 后來 時間: 2025-3-25 07:54 作者: avulsion 時間: 2025-3-25 12:29 作者: 茁壯成長 時間: 2025-3-25 19:54 作者: 溺愛 時間: 2025-3-25 22:31
0070-217X mmunotherapy, and for the therapy of autoimmune diseases...Written by internationally respected scientists, this book will appeal to basic scientists, clinicians, drug development researchers, and advanced students alike..978-3-319-88684-8978-3-319-68929-6Series ISSN 0070-217X Series E-ISSN 2196-9965 作者: 瑣事 時間: 2025-3-26 00:29
Book 2017. Playing essential roles in immune homeostasis, they could offer new targets for cancer immunotherapy, and for the therapy of autoimmune diseases...Written by internationally respected scientists, this book will appeal to basic scientists, clinicians, drug development researchers, and advanced students alike..作者: 種族被根除 時間: 2025-3-26 07:18 作者: 過多 時間: 2025-3-26 09:35
Enrique Ballestero,Carlos Romeromanner. Moreover, the combined expression of LAG-3 and CD49b identifies IL-10-producing Treg cells in mice and humans more specifically. Recently, LAG-3 has gained more attention in the context of immune checkpoints because it believed to be related to T cell tolerance and exhausted T cells that inf作者: 有偏見 時間: 2025-3-26 13:53 作者: 注視 時間: 2025-3-26 18:05
Multiple Decrement Models in Insurancedences that PD-1 signal is one of the main factors of cancer immune escape in humans. The dramatic efficacy of PD-1 blockade in cancer immunotherapy, promises the control of other immune diseases by PD-1 signal modulation. In this review, we summarize the history of PD-1, subsequent basic studies, a作者: tinnitus 時間: 2025-3-27 00:08
Multiple Drug Resistance in Cancerlls can also provide cell-extrinsic regulation on other autoreactive T cells, and are considered to provide an essential regulatory mechanism for FoxP3+?regulatory T cells. Genetic deficiency of CTLA-4 leads to CD28-mediated severe autoimmunity in mice and humans, suggesting its function as a fundam作者: Vasoconstrictor 時間: 2025-3-27 01:12 作者: 詞匯記憶方法 時間: 2025-3-27 05:55 作者: 陰險 時間: 2025-3-27 12:53
https://doi.org/10.1007/978-3-319-47759-6une response. Notably, we review PTP regulatory properties in macrophages, antigen-presenting dendritic cells, and T cells. Overall, we present the PTP gene family as a remarkable source of novel checkpoint inhibitors wherein lies a great number of new targets for immunotherapies.作者: Offbeat 時間: 2025-3-27 16:02 作者: 機制 時間: 2025-3-27 21:33
Book 2017ints: T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death-1 (PD-1). It shows that antagonistic antibodies against these two molecules are highly effective in the treatment of various cancers and that PD-1 and CTLA-4 have been linked to the suppression of T-cell receptor signaling an作者: Medley 時間: 2025-3-27 22:20
Tim-3, Lag-3, and TIGITTim-3, Lag-3, and TIGIT and how they regulate T cell function, maintenance of self-tolerance, their role in regulating ongoing T cell responses at peripheral tissues, and their synergistic effects in regulating autoimmunity and antitumor responses.作者: Microaneurysm 時間: 2025-3-28 04:05
0070-217X erstanding and application of extended immune checkpoint reg.This volume reviews the current state of research on immune checkpoints and offers novel concepts. It discusses the two most important immune checkpoints: T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death-1 (PD-1). It sh作者: myalgia 時間: 2025-3-28 09:47
https://doi.org/10.1007/978-3-319-65425-6 responses. Moreover, we will review the current reports regarding miRNAs in human immunological diseases. Finally, we will also address the emerging roles of other non-coding RNAs, long non-coding RNAs (lncRNAs) in particular, in the regulation of the immune system.作者: 失望昨天 時間: 2025-3-28 12:32
MicroRNA in Immune Regulation responses. Moreover, we will review the current reports regarding miRNAs in human immunological diseases. Finally, we will also address the emerging roles of other non-coding RNAs, long non-coding RNAs (lncRNAs) in particular, in the regulation of the immune system.作者: 嫻熟 時間: 2025-3-28 15:33 作者: 繁忙 時間: 2025-3-28 18:50
Regulatory T Cells: Molecular and Cellular Basis for Immunoregulationtion factor FOXP3. Tregs are proven to play central roles in the maintenance of self-tolerance in healthy individuals. Tregs are involved in maintaining immune homeostasis: they protect hosts from developing autoimmune diseases and allergy, whereas in malignancies, they promote tumor progression by 作者: fabricate 時間: 2025-3-29 00:46 作者: CORD 時間: 2025-3-29 03:17
Regulatory Dendritic Cellsered to be essential antigen (Ag)-presenting cells (APCs) that play crucial roles in activation and fine-tuning of innate and adaptive immunity under inflammatory conditions, as well as induction of immune tolerance to maintain immune homeostasis under steady-state conditions. Furthermore, DC functi作者: bizarre 時間: 2025-3-29 10:12
Role of PD-1 in Immunity and Diseasesity, mainly T cells, and B cells, are able to distinguish self from non-self, they sometimes attack the body’s tissues because of imperfect central tolerance. Several immune check points developed to limit overactivation of these cells. One of the most important immune checkpoints is programmed cell作者: GEN 時間: 2025-3-29 11:33
CTLA-4, an Essential Immune-Checkpoint for T-Cell Activationg costimulatory receptors, CD28 and CTLA-4, on T cells bind to the same ligands (CD80 and CD86) on antigen-presenting cells (APCs), and provide positive and negative feedback for T-cell activation, respectively. Early studies suggested that CTLA-4 is induced on activated T cells and binds to CD80/CD作者: 手工藝品 時間: 2025-3-29 19:02 作者: Frequency-Range 時間: 2025-3-29 19:47 作者: 反叛者 時間: 2025-3-30 01:07
Mining the Complex Family of Protein Tyrosine Phosphatases for Checkpoint Regulators in Immunityrity are present in immune cells and play various roles in either inhibiting or promoting the duration and amplitude of signaling cascades. Several PTPs, including TC-PTP (PTPN2) and SHP-1 (PTPN6), have been recognized as being crucial for maintaining proper immune response and self-tolerance, and h作者: 新陳代謝 時間: 2025-3-30 08:01
Immune Regulation by Ubiquitin Tagging as Checkpoint Codefrom attacking its own tissues to maintain immune tolerance. The balance of activation and tolerance is tightly controlled by diverse mechanisms, since breakdown of tolerance could result in disastrous consequences such as the development of autoimmune diseases. One of the mechanisms is by the means作者: 半圓鑿 時間: 2025-3-30 09:01
