標題: Titlebook: Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery; Electrically Mediate Mark J. Jaroszeski,Richard Heller,Richard Gilb [打印本頁] 作者: Constrict 時間: 2025-3-21 17:00
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery影響因子(影響力)
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery影響因子(影響力)學科排名
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery網(wǎng)絡公開度
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery網(wǎng)絡公開度學科排名
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery被引頻次
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery被引頻次學科排名
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery年度引用
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery年度引用學科排名
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery讀者反饋
書目名稱Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery讀者反饋學科排名
作者: Pseudoephedrine 時間: 2025-3-21 21:49
Instrumentation and Electrodes for In Vivo Electroporation protocols aid the researcher in selecting appropriate procedures; commercial instrumentation is readily available and discussed (.). The more recent transition to applying EP to living tissue poses a new set of requirements and few practical guidelines are available.作者: HEPA-filter 時間: 2025-3-22 02:57 作者: 要塞 時間: 2025-3-22 06:44 作者: Needlework 時間: 2025-3-22 11:45 作者: 全國性 時間: 2025-3-22 15:29 作者: 全國性 時間: 2025-3-22 20:07 作者: Orgasm 時間: 2025-3-22 23:09
In Vitro and Ex Vivo Gene Delivery to Cells by Electroporationthat the barrier function of the membrane is instantaneously compromised. During such time, genetic materials may travel across the membrane. For a successful gene transfer process, the barrier function of the cell membrane is rapidly restored, and the cell survives. The electrotransfection process 作者: Frenetic 時間: 2025-3-23 01:21
Delivery of Genes In Vivo Using Pulsed Electric Fieldsne breakdown in an in vitro environment in the 1960s and 1970s (.–.). This early research led to the current understanding that exposing cells to intense electric fields induces a transmembrane potential that is superposed on the resting potential. Induced potentials of sufficient magnitude cause a 作者: 慟哭 時間: 2025-3-23 09:27 作者: palliate 時間: 2025-3-23 13:40
Mechanistic Studies of Skin Electroporation Using Biophysical Methodsion was first observed almost three decades ago. Determining the mechanism by which such pulses permeabilize the complex, multilamellar bilayer structures in skin poses an even greater challenge. To address this issue, a range of methods have been employed to perform biophysical characterization for作者: CUB 時間: 2025-3-23 15:04 作者: MORT 時間: 2025-3-23 21:18 作者: Mindfulness 時間: 2025-3-23 23:46
Treatment of Multiple Spontaneous Breast Tumors in Mice Using Electrochemotherapyrmeabilization. Electrochemotherapy has been proven to be highly efficient as a local antitumor treatment on transplanted tumors (.). Indeed, electrochemotherapy resulted in high rates of tumor responses and even cures in preclinical trials on different experimental murine tumors (.). Treatment effi作者: Anecdote 時間: 2025-3-24 03:17 作者: FOLLY 時間: 2025-3-24 07:52 作者: Cleave 時間: 2025-3-24 14:12 作者: fertilizer 時間: 2025-3-24 16:37 作者: hysterectomy 時間: 2025-3-24 21:38 作者: Gratulate 時間: 2025-3-25 01:41
Mechanistic Studies of Skin Electroporation Using Biophysical Methodsures in skin poses an even greater challenge. To address this issue, a range of methods have been employed to perform biophysical characterization for skin electroporation studies. In this chapter, we provide an overview of these methods and highlight representative findings which biophysical characterization has yielded.作者: 走調(diào) 時間: 2025-3-25 05:32
Handbuch Essst?rungen und Adipositasthus comprises two steps. The first step is electroporation, which is governed by the electrical properties of the cell and the suspension medium. The controlling parameters are mainly electrical. The second step is recovery, which must take into account the biological characteristics of the cells. We consider these two steps in this chapter.作者: 神圣將軍 時間: 2025-3-25 10:31 作者: 羊欄 時間: 2025-3-25 14:08
Book 2000 that the primary effect that electrical treatment has on cells is an induced increase in the permeability of membranes to exogenous molecules. This state of increased permeability was noted to be temporary and could be induced with little or no effect on cell viability. This physical phenomenon was作者: mendacity 時間: 2025-3-25 19:41 作者: 招惹 時間: 2025-3-25 23:09 作者: observatory 時間: 2025-3-26 00:51 作者: mastopexy 時間: 2025-3-26 05:00
Handbuch Erwachsenenbildung/Weiterbildungy reseal. Its molecular definition remains unknown. This phenomenon is now commonly known as .. The former term implies that physical pores are created in the lipid matrix. However their existence has never been clearly demonstrated. The term electroporation is therefore rather misleading.作者: 魯莽 時間: 2025-3-26 11:06 作者: Banister 時間: 2025-3-26 15:48
,Ethische Theorien im überblick,ures in skin poses an even greater challenge. To address this issue, a range of methods have been employed to perform biophysical characterization for skin electroporation studies. In this chapter, we provide an overview of these methods and highlight representative findings which biophysical characterization has yielded.作者: 乞丐 時間: 2025-3-26 18:01 作者: Microaneurysm 時間: 2025-3-27 00:38 作者: GONG 時間: 2025-3-27 02:33 作者: Electrolysis 時間: 2025-3-27 08:13 作者: Aqueous-Humor 時間: 2025-3-27 09:56
Electrochemotherapytating the delivery of a chemotherapeutic drug into tumor cells at concentrations that are sufficient for effective cell killing and, at the same time, to minimize the drug concentration in normal tissue.作者: adhesive 時間: 2025-3-27 15:25 作者: 用手捏 時間: 2025-3-27 19:46
Electroporation of Muscle Tissue In Vivo localized cancers, the question of normal tissue sensitivity to electroporation needs to be investigated. Finally, efficient in vivo gene transfection to muscle tissue by electroporation has recently been reported (.,.), warranting increased knowledge on in vivo electroporation of muscle tissue.作者: Engaged 時間: 2025-3-27 23:52
Treatment of Rat Bladder Cancer With Electrochemotherapy In Vivoase in the concentration of Bleomycin, in bladder cancer cells in vitro and in normal bladder tissue of rats in vivo (.). Here we introduce our method to assess the effectiveness of this therapy for rat’s bladder cancer.作者: 是貪求 時間: 2025-3-28 05:15
In Vitro and Ex Vivo Gene Delivery to Cells by Electroporationthus comprises two steps. The first step is electroporation, which is governed by the electrical properties of the cell and the suspension medium. The controlling parameters are mainly electrical. The second step is recovery, which must take into account the biological characteristics of the cells. We consider these two steps in this chapter.作者: 粗魯?shù)娜?nbsp; 時間: 2025-3-28 09:21
Delivery of Genes In Vivo Using Pulsed Electric Fieldsdielectric breakdown of the membrane. This physical phenomenon was termed electroporation, or electropermeabilization, because it was observed that molecules that do not normally pass through the membrane gain intracellular access after the cells were treated with electric fields.作者: Panther 時間: 2025-3-28 14:26
Book 2000iated delivery have tremendous potential for the treatment of human disease. For example, the ef- cient delivery of drugs and plasmid DNA has strong implications for improving standard therapies, as well as gene therapies. This potential was realized about 12 years ago when electric pulses were used作者: 贊成你 時間: 2025-3-28 16:45 作者: invulnerable 時間: 2025-3-28 22:45
Electrochemotherapy, Electrogenetherapy, and Transdermal Drug DeliveryElectrically Mediate作者: HEDGE 時間: 2025-3-29 00:09 作者: 連接 時間: 2025-3-29 06:33 作者: Fortify 時間: 2025-3-29 09:59 作者: BOON 時間: 2025-3-29 13:52 作者: 歡騰 時間: 2025-3-29 16:13
Numerical Modeling for In Vivo Electroporationisolated cells (.). Selected electric field intensity, appropriate for electroporation, should at the same time not exceed the value which will cause irreversible permeabilization or even death of the cell (.). This is particularly important for electro-gene transfection.作者: GIBE 時間: 2025-3-29 22:33
The Basis of Electrochemotherapy drugs for which the plasma membrane is a barrier that limits their access inside the cell [termed nonpermeant drugs] (.). As illustrated in the various protocols reported in this volume, electrochemotherapy using bleomycin is efficient to eradicate subcutaneously transplanted and spontaneous small 作者: FLAG 時間: 2025-3-30 02:35 作者: 恭維 時間: 2025-3-30 04:35
Treatment of Human Pancreatic Tumors Xenografted in Nude Mice by Chemotherapy Combined with Pulsed Ecan inhibit tumor growth in vivo in human pancreatic cancer xenografts. This was demonstrated in nude mice with BxPC-3 xenografts using fluorouracil, cisplatin, and doxorubicin with a consequent size reduction of the tumors between 72% and 79%, compared to the controls at day 28 after the first trea作者: 你敢命令 時間: 2025-3-30 11:46
Sozialisationstheorie und Erwachsenenbildungd permeable, transiently and reversibly, by electric voltage pulses. It is of great practical importance that the . structural changes induced by ME, condition the electroporated membrane for a variety of . processes, such as, for instance, the permeation of otherwise impermeable substances.作者: Ligament 時間: 2025-3-30 16:18 作者: ESPY 時間: 2025-3-30 19:12 作者: 貪婪的人 時間: 2025-3-31 00:32 作者: Pericarditis 時間: 2025-3-31 04:07
Erwachsenenbildung im Nationalsozialismusabilizing electric pulses (.–.). More generally, a new form of vectorization is achieved by the combination of nonpermeant molecules with intracellular targets and of a physical perturbation that locally permeabilizes the cells. This vectorization does not require chemical, biochemical or biological作者: 真 時間: 2025-3-31 05:26 作者: 陶醉 時間: 2025-3-31 09:52 作者: voluble 時間: 2025-3-31 15:13
Handbuch Essst?rungen und Adipositasthat the barrier function of the membrane is instantaneously compromised. During such time, genetic materials may travel across the membrane. For a successful gene transfer process, the barrier function of the cell membrane is rapidly restored, and the cell survives. The electrotransfection process 作者: nuclear-tests 時間: 2025-3-31 18:41
Psychodynamische Modellvorstellungenne breakdown in an in vitro environment in the 1960s and 1970s (.–.). This early research led to the current understanding that exposing cells to intense electric fields induces a transmembrane potential that is superposed on the resting potential. Induced potentials of sufficient magnitude cause a 作者: 官僚統(tǒng)治 時間: 2025-4-1 00:26
https://doi.org/10.1007/978-3-476-05192-9er to transdermal drug delivery. The stratum corneum is made up of corneocytes, which are flattened remnants of cells, surrounded by lipid bilayer membranes (.,.). Because lipid-based structures tend to exclude charged species, the multilamellar arrangement acts as a “brick wall” (.) to prevent ioni作者: nocturnal 時間: 2025-4-1 04:50
,Ethische Theorien im überblick,ion was first observed almost three decades ago. Determining the mechanism by which such pulses permeabilize the complex, multilamellar bilayer structures in skin poses an even greater challenge. To address this issue, a range of methods have been employed to perform biophysical characterization for作者: Acupressure 時間: 2025-4-1 06:54
,Ethische Theorien im überblick,.). Preclinical experiments were required to demonstrate the in vivo applicability of these observations. Obviously, the most convenient laboratory animal model to test new antitumor treatments is the mouse. Indeed, there exist many tumors of different histological types which can be transplanted in作者: arthroscopy 時間: 2025-4-1 13:30 作者: 彈藥 時間: 2025-4-1 18:11 作者: BLANK 時間: 2025-4-1 20:18