標(biāo)題: Titlebook: Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2; Part A Kenneth V. Honn,Santosh Nigam,Lawrence J. Ma [打印本頁(yè)] 作者: 遠(yuǎn)見(jiàn) 時(shí)間: 2025-3-21 17:50
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2影響因子(影響力)
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2影響因子(影響力)學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2被引頻次
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2被引頻次學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2年度引用
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2年度引用學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2讀者反饋
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2讀者反饋學(xué)科排名
作者: 現(xiàn)代 時(shí)間: 2025-3-21 22:14 作者: ARBOR 時(shí)間: 2025-3-22 01:53
https://doi.org/10.1007/978-981-15-3738-7n and distribution of 12-LOX, we therefore analyzed the distribution of both 12-LOX activity and of 12-LOX protein in murine Lewis lung carcinoma cells (3LL cells) and compared their 12-LOX activity with homologous 12-LOX activity in platelets. Further we asked whether activation of the 12-LOX enzym作者: 頌揚(yáng)本人 時(shí)間: 2025-3-22 07:02
https://doi.org/10.1007/978-3-319-94036-6(4–8). It encodes a 600 amino acid protein including a signal peptide containing ~24 amino acids. There are 3 potential N-glycosylation sites. PGHS-2 cDNA codes for a 602 amino acid protein with a molecular weight indistinguishable from that of PGHS-I on Western blots. Although several laboratories 作者: Lipoprotein(A) 時(shí)間: 2025-3-22 11:49 作者: Nebulizer 時(shí)間: 2025-3-22 16:13
Activation of 5-Lipoxygenase in Whole Polymorphonuclear Leukocytes by Arachidonic Acid: Evidence of kage of FLAP suppresses leukotriene formation in A23187 challenged cells (7), b) the expression of both 5-LO and FLAP is needed for leukotriene formation in response to A23187 (6), and c) when differentiation of HL-60 cells towards granulocytes is induced, both 5-LO and FLAP are expressed (8). Never作者: Nebulizer 時(shí)間: 2025-3-22 20:46
Intracellular Distribution, Activity, and Ca2+-Dependent Translocation of 12-Lipoxygenase in Lewis Ln and distribution of 12-LOX, we therefore analyzed the distribution of both 12-LOX activity and of 12-LOX protein in murine Lewis lung carcinoma cells (3LL cells) and compared their 12-LOX activity with homologous 12-LOX activity in platelets. Further we asked whether activation of the 12-LOX enzym作者: outer-ear 時(shí)間: 2025-3-22 23:22 作者: 有雜色 時(shí)間: 2025-3-23 04:53 作者: Stricture 時(shí)間: 2025-3-23 05:53 作者: 容易懂得 時(shí)間: 2025-3-23 12:34 作者: 有發(fā)明天才 時(shí)間: 2025-3-23 16:34 作者: figurine 時(shí)間: 2025-3-23 20:26
Eric C. K. Cheng,Joanna K. M. Chantood. Lipid peroxidation, phospholipase A. activity and myeloperoxidase activity were increased in colorectal cancers compared with macroscopically normal tissues (Otamiri et al. 1989). Varying amounts of total arachidonic acid in the phospholipids of colorectal tumors compared to normal associated 作者: SSRIS 時(shí)間: 2025-3-23 23:39
https://doi.org/10.1057/9780230299016 which contains a non-heme iron. The common characteristics of the reaction catalyzed by .-type lipoxygenases (LOX) include:. i) substrates with a .-1,4-pentadiene structure, preferably in afree fatty acid, ii) a three step reaction mechanism consisting of hydrogen abstraction at C(3) of the pentadi作者: Transfusion 時(shí)間: 2025-3-24 05:11 作者: 思想流動(dòng) 時(shí)間: 2025-3-24 06:31
https://doi.org/10.1007/978-981-15-3738-7(2–4), as well as in human (5,6) and rodent tumor cells (7,8). In tumor cells, the major metabolite, 12(S)-HETE, regulates their metastatic potential (9–11) through a protein kinase C-dependent mechanism (7). The intracellular distribution of 12-LOX activity varies between different cells ranging fr作者: Density 時(shí)間: 2025-3-24 13:33
Ying Xu,Glenn Patmore,Paul J Gollan is the first step in prostaglandin synthesis, and is also the rate limiting step in this pathway. In addition, the PHS protein is inactivated at a rapid rate during catalysis. Thus, the regulation of PHS expression has a direct and significant effect on the rate of prostaglandin synthesis.作者: 不能強(qiáng)迫我 時(shí)間: 2025-3-24 15:07 作者: seroma 時(shí)間: 2025-3-24 22:45 作者: 使乳化 時(shí)間: 2025-3-25 00:55
https://doi.org/10.1007/978-0-387-71485-1eicosanoids. Eicosanoid formation has been shown to be elicited by a number of particulate (bacteria, viruses, zymosan, immune complexes) and soluble (phorbol ester, PAF, C3a, fluoride, calcium ionophore, LPS, cytokines) agents. The release of arachidonic acid (AA) and eicosanoids in these cells has作者: 胰臟 時(shí)間: 2025-3-25 06:49 作者: Autobiography 時(shí)間: 2025-3-25 08:30 作者: Herd-Immunity 時(shí)間: 2025-3-25 11:59
Challenges of School Leadershipalyzes the conversion of arachidonic acid into prostaglandin H. (PGH.). Two isozymes of the enzyme (PGHS-1 and PGHS-2) exist and have different modes of expression and tissue distributions (2). The first reaction catalyzed by PGHS, the cyclooxygenase step (3), inserts two molecules of oxygen into ar作者: 我不怕?tīng)奚?nbsp; 時(shí)間: 2025-3-25 16:27
Maurizio Morisio,Marco Torchianolized metal affinity, and hydroxy apatite chromatography..The homogenous protein exhibited spectral characteristics of a heme-thiolate protein (P450) like the enzyme purified earlier from porcine microsomes and had an apparent mass of 52 kDa on SDS/PAGE. Three peptides from an endoproteinase Lys-C d作者: 線 時(shí)間: 2025-3-25 20:35
https://doi.org/10.1007/978-3-319-94036-6acid (AA) to prostaglandin G. (PGG.) and then PGH. (1). PGH. is the precursor of biologically active and physiologically important prostanoids, i.e. thromboxane A. (TXA.), prostacyclin (PGI.), PGE., PGF. and PGD.. PGHS, hence, occupies a pivotal position in prostanoid biosynthesis. Two isoforms of P作者: AVANT 時(shí)間: 2025-3-26 00:59
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2978-1-4615-5325-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 售穴 時(shí)間: 2025-3-26 06:11 作者: 來(lái)自于 時(shí)間: 2025-3-26 10:12 作者: 墊子 時(shí)間: 2025-3-26 13:59 作者: 加入 時(shí)間: 2025-3-26 18:22 作者: harmony 時(shí)間: 2025-3-26 22:17 作者: 托運(yùn) 時(shí)間: 2025-3-27 04:34 作者: HAIRY 時(shí)間: 2025-3-27 06:08 作者: adhesive 時(shí)間: 2025-3-27 12:21
0065-2598 transduction. One of the most exciting developments exploredwithin this collection of articles is the expression of the novelisoform of cyclooxygenase (cox-2), which may play a large rolein the development of anti-inflammatory drugs.978-1-4613-7430-5978-1-4615-5325-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: myelography 時(shí)間: 2025-3-27 15:03
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/e/image/303153.jpg作者: HERTZ 時(shí)間: 2025-3-27 18:03 作者: labile 時(shí)間: 2025-3-28 01:21
978-1-4613-7430-5The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines作者: 彈藥 時(shí)間: 2025-3-28 03:30
Book 1997ion. One of the most exciting developments exploredwithin this collection of articles is the expression of the novelisoform of cyclooxygenase (cox-2), which may play a large rolein the development of anti-inflammatory drugs.作者: Carcinogenesis 時(shí)間: 2025-3-28 09:17 作者: 烤架 時(shí)間: 2025-3-28 11:44
Dangeni,Rui He,Natthaphon Tripornchaisaked. The increases in PGH synthase-1 were accompanied by an enhanced capacity of the cells to produce PGE.. The current findings indicate that expression of PGH synthase-1 is greatly enhanced in a promonocytic cell line by treatment with an agent that induces differentiation.作者: 間接 時(shí)間: 2025-3-28 14:47
Challenges of School Leadershiptain. While PGHS is an integral membrane protein, found mainly in the endoplasmic reticulum, its mode of insertion into biological membranes was unknown until recently. In this communication, we described the structure of ovine PGHS-1, recently determined by X-ray crystallography at 3.5 ? (4) using crystals grown in the presence of detergents (5).作者: Insul島 時(shí)間: 2025-3-28 20:06 作者: 小樣他閑聊 時(shí)間: 2025-3-29 00:45 作者: 懸掛 時(shí)間: 2025-3-29 06:50 作者: 你不公正 時(shí)間: 2025-3-29 07:25 作者: plasma-cells 時(shí)間: 2025-3-29 12:56
Julia Romanowska,Anna Nyberg,T?res Theorell associated by virtue of their Srchomology (SH2) domains. In the case of hormones, neurotransmitters and certain other agonists whose receptors contain seven membrane-spanning segments, the signal is transduced by G-proteins to β-isozymes of PI-PLC.作者: 滔滔不絕地說(shuō) 時(shí)間: 2025-3-29 18:22 作者: 大洪水 時(shí)間: 2025-3-29 22:10
Regulation of Phosphoinositide Phospholipases by G-Proteins associated by virtue of their Srchomology (SH2) domains. In the case of hormones, neurotransmitters and certain other agonists whose receptors contain seven membrane-spanning segments, the signal is transduced by G-proteins to β-isozymes of PI-PLC.作者: 調(diào)整校對(duì) 時(shí)間: 2025-3-30 03:09
Properties of Prostacyclin Synthasesomes from cultured endothelial cells. After treatment with IL-1 the activity of the cells in producing 6-keto-PGF. increased about threefold over 27 h which was accompanied by an increase in PGIS mass. A monoclonal antibody was used to set up an ELISA which served for the quantitation of PGIS in bovine tissues.作者: APEX 時(shí)間: 2025-3-30 06:51 作者: dapper 時(shí)間: 2025-3-30 09:59
Non-Enzymatic Rearrangement of Leukotriene A4 to 5-Keto-(7E,9E,11Z,14Z)-Eicosatetraenoic Acid in Aqud non-enzymatic hydrolysis in aqueous solution at neutral pH with a half-time of few seconds. The hydrolysis products have been identified fifteen years ago and shown to correspond mainly to an equimolar mixture of 6-trans-LTB. and 6-trans-12-epi-LTB. with smaller amounts of 5,6-dihydroxyeicosatetraenoic acids (5,6-diHETE) (1,2).作者: 過(guò)渡時(shí)期 時(shí)間: 2025-3-30 15:55
Regulation of Eicosanoid Synthesis in Liver Macrophages(phorbol ester, PAF, C3a, fluoride, calcium ionophore, LPS, cytokines) agents. The release of arachidonic acid (AA) and eicosanoids in these cells has been shown to be controlled by glucocorticoids (1), intracellular pH (2), calcium ions (3,4), protein kinase (PK) C (5–7) and albumin in the cell media (8).作者: cipher 時(shí)間: 2025-3-30 20:33
Comparison of Arachidonic Acid Metabolism by Normal, Pre-Cancerous and Neoplastic Epithelial Cell Lilites on tumor growth and/or host immune function, and 3) the effects of inhibitors of AA metabolism on tumor growth . and .. Much attention has been focused on prostaglandin E. (PGE.) due to its multiple immunosuppressive effects. The importance of other cyclooxygenase and lipoxgenase metabolites has not been adequately addressed.作者: 清醒 時(shí)間: 2025-3-31 00:46 作者: Occupation 時(shí)間: 2025-3-31 00:57
0065-2598 transduction. One of the most exciting developments exploredwithin this collection of articles is the expression of the novelisoform of cyclooxygenase (cox-2), which may play a large rolein the development of anti-inflammatory drugs.978-1-4613-7430-5978-1-4615-5325-0Series ISSN 0065-2598 Series E-I作者: 充氣球 時(shí)間: 2025-3-31 06:16
Eric C. K. Cheng,Joanna K. M. Chanrmal tissues (Otamiri et al. 1989). Varying amounts of total arachidonic acid in the phospholipids of colorectal tumors compared to normal associated mucosa have been reported (Yazici et al. 1991; Neoptolemos et al. 1991).作者: Lice692 時(shí)間: 2025-3-31 12:33 作者: 束縛 時(shí)間: 2025-3-31 16:50
https://doi.org/10.1007/978-0-387-71485-1(phorbol ester, PAF, C3a, fluoride, calcium ionophore, LPS, cytokines) agents. The release of arachidonic acid (AA) and eicosanoids in these cells has been shown to be controlled by glucocorticoids (1), intracellular pH (2), calcium ions (3,4), protein kinase (PK) C (5–7) and albumin in the cell media (8).作者: 發(fā)酵劑 時(shí)間: 2025-3-31 18:51
The Future of Public Sector Leadership,lites on tumor growth and/or host immune function, and 3) the effects of inhibitors of AA metabolism on tumor growth . and .. Much attention has been focused on prostaglandin E. (PGE.) due to its multiple immunosuppressive effects. The importance of other cyclooxygenase and lipoxgenase metabolites has not been adequately addressed.作者: OATH 時(shí)間: 2025-3-31 23:12 作者: RLS898 時(shí)間: 2025-4-1 04:55
The Effects of Group II Phospholipase A, on ,-Induced Metastasisy and metastasis in animal model systems (1–3). Therefore, the specific .-induced alterations which facilitate primary tumor growth and metastasis are clearly of interest. The introduction of a . gene product (p21) in eucaryotic cells causes transformation .. This transformation has also been associ作者: tangle 時(shí)間: 2025-4-1 06:02 作者: 受人支配 時(shí)間: 2025-4-1 13:12
High Molecular Weight Phospholipase A2: Its Occurrence and Quantification in Human Colon Cancer and tood. Lipid peroxidation, phospholipase A. activity and myeloperoxidase activity were increased in colorectal cancers compared with macroscopically normal tissues (Otamiri et al. 1989). Varying amounts of total arachidonic acid in the phospholipids of colorectal tumors compared to normal associated 作者: 神圣在玷污 時(shí)間: 2025-4-1 17:30
-Type Lipoxygenase and Cyclooxygenase Reaction Box Models Characterizing the Stereochemistry of the which contains a non-heme iron. The common characteristics of the reaction catalyzed by .-type lipoxygenases (LOX) include:. i) substrates with a .-1,4-pentadiene structure, preferably in afree fatty acid, ii) a three step reaction mechanism consisting of hydrogen abstraction at C(3) of the pentadi
