標(biāo)題: Titlebook: Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury; Proceedings of the 1 Kenneth V. Honn,Lawrence J. Marnett,Thomas L. W [打印本頁(yè)] 作者: retort 時(shí)間: 2025-3-21 16:20
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury影響因子(影響力)
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury影響因子(影響力)學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury被引頻次
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury被引頻次學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury年度引用
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury年度引用學(xué)科排名
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury讀者反饋
書(shū)目名稱Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury讀者反饋學(xué)科排名
作者: 胡言亂語(yǔ) 時(shí)間: 2025-3-21 23:42
Transcellular Biosynthesis of Leukotrienes: Is Leukotriene A4 a Mediator? biochemical studies (1,2). In most cases, these studies involved the addition of radiolabeled arachidonic acid to homogenous cell suspensions with characterization of the resultant radiolabeled metabolites. Thus, most of the studies during the 1960s and 1970s were designed to establish those oxidat作者: prolate 時(shí)間: 2025-3-22 02:51 作者: Irrigate 時(shí)間: 2025-3-22 07:19
Fatty Acid Cyclooxygenase Metabolism of Arachidonic Acid in Human Tumor Cells related to tumor metastasis, cell proliferation, tumor promotion and host immunoregulation (1–23). There is substantial evidence that human tumor cells may synthesize significant quantities of prostaglandins. Elevated production of prostaglandin E2 (PGE.) has been demonstrated in lung cancer patien作者: ICLE 時(shí)間: 2025-3-22 12:09 作者: 影響帶來(lái) 時(shí)間: 2025-3-22 13:21
Localization and Expression of the Eicosanoid Metabolizing P4501VA Gene Family in Rat Tissues and He cholesterol, arachidonic acid, leukotrienes and prostaglandins (2,3). Three genes of the rat 1VA gene family have been characterized and shown to be induced by tumor-promoting hypolipidemic drugs (2,3). The physiological function of the ω-oxidized products remains largely undefined. However, the ex作者: 影響帶來(lái) 時(shí)間: 2025-3-22 20:23 作者: 圍裙 時(shí)間: 2025-3-23 00:55 作者: licence 時(shí)間: 2025-3-23 03:05
Prevention of Peroxide Produced DNA Strand Scission in Human Tumor Cells by Lipoxygenase Inhibitorseral orders of magnitude more toxic to cells at 37° C than at 0° C (1). At low doses, these agents produce mutation and transformation in various cells. The phorbol esters, transforming agents which are structurally unrelated to peroxide have also been reported to produce oxidative damage in cells. 作者: 枯燥 時(shí)間: 2025-3-23 05:45 作者: Brain-Imaging 時(shí)間: 2025-3-23 13:20 作者: 親愛(ài) 時(shí)間: 2025-3-23 16:30
Fatty Acid-Induced Modulation of Carcinogenesis in Human and Mouse Mammary Explant Culturesy 25% of women developing breast cancer present identifiable risk factors (2). Thus, in majority of women the causative factor(s), and therefore relative risk for developing breast cancer remains unknown.作者: 磨坊 時(shí)間: 2025-3-23 21:51
Radiation Protection and Cancer Therapy by Linoleatetected mouse bone marrow cells against radiation damage even when injected an hour or more after exposure of the mice to gamma rays (2). It seems likely, therefore, that combined radiation and LA therapy may be useful for the control of selected cancers. We have begun an investigation of the combine作者: Campaign 時(shí)間: 2025-3-23 23:45
Developing Christian Servant LeadershipDifferent studies have shown, that human tumors are able to synthesize prostanoids (1–3) with significant increases in production during tumor development (4,5). An influence of cyclooxygenase metabolites of arachidonic acid on processes such as cell proliferation, migration, adherence, and hemostatic mechanisms were suggested.作者: OCTO 時(shí)間: 2025-3-24 04:56
Bob Lumley,Michael O’ShaughnesseyRecently, we reported formation of lipoxins from endogenous substrate, via platelet-dependent lipoxygenation of granulocyte-derived leukotriene (LT)A. (1). Furthermore, human platelet suspensions transformed synthetic LTA. to lipoxins. The platelets also efficiently converted LTA. to cysteinyl-containing leukotrienes (2).作者: 易于交談 時(shí)間: 2025-3-24 09:21 作者: institute 時(shí)間: 2025-3-24 11:43
The Occurence of Thromboxane Synthase in Tumor CellsDifferent studies have shown, that human tumors are able to synthesize prostanoids (1–3) with significant increases in production during tumor development (4,5). An influence of cyclooxygenase metabolites of arachidonic acid on processes such as cell proliferation, migration, adherence, and hemostatic mechanisms were suggested.作者: Offbeat 時(shí)間: 2025-3-24 16:42
Deficient Lipoxin Formation in Chronic Myelogenous LeukemiaRecently, we reported formation of lipoxins from endogenous substrate, via platelet-dependent lipoxygenation of granulocyte-derived leukotriene (LT)A. (1). Furthermore, human platelet suspensions transformed synthetic LTA. to lipoxins. The platelets also efficiently converted LTA. to cysteinyl-containing leukotrienes (2).作者: 匍匐前進(jìn) 時(shí)間: 2025-3-24 21:29 作者: 清真寺 時(shí)間: 2025-3-25 00:32
https://doi.org/10.1007/978-1-4615-3874-5Tumor; carcinogenesis; cell; cellular differentiation; leukemia; melanoma; mutagen; ovarian cancer; preventi作者: Airtight 時(shí)間: 2025-3-25 04:52 作者: averse 時(shí)間: 2025-3-25 08:41 作者: cochlea 時(shí)間: 2025-3-25 12:49 作者: 性冷淡 時(shí)間: 2025-3-25 19:40
https://doi.org/10.1057/9781137341570, and produces 12S-hydroperoxy-5,8,10,14-eicosatetraenoic acid (Figure 1). Since the enzyme was found in platelets as the first mammalian lipoxygenase (1,2), the 12-lipoxygenase has been found in a variety of tissues of a number of animal species (3,4). In addition to 12-lipoxygenase, several more l作者: NIL 時(shí)間: 2025-3-25 22:29 作者: reception 時(shí)間: 2025-3-26 02:26
Sunn Hemp: A Climate-Smart Crop,esumed radical scavengers exhibit radical generating activity under certain conditions. For example, vitamin C (L-(+)-ascorbic acid) is well known to act as an antioxidant and a prooxidant (5–10). Its antioxidant activity derives from its ability to reduce peroxyl radicals that propagate lipid perox作者: 踉蹌 時(shí)間: 2025-3-26 05:23 作者: BILIO 時(shí)間: 2025-3-26 10:36 作者: Fermentation 時(shí)間: 2025-3-26 15:41 作者: 冒失 時(shí)間: 2025-3-26 19:39 作者: Recessive 時(shí)間: 2025-3-26 23:27
Developing Countries in British Fictionlular genes into oncogenes (1) the ultimate course and frequency of the neoplastic process are largely determined by an interplay of exogenous and endogenous factors (1,2). Permissive factors such as hormones act as co-transforming agents and potentiate carcinogenesis (1). These are balanced under n作者: myelography 時(shí)間: 2025-3-27 03:57 作者: 一夫一妻制 時(shí)間: 2025-3-27 07:52
Trade and Development in GATT and the WTO,gens/carcinogens in the environment, but are also formed during various kinds of cellular metabolism. We previously observed that the C-8 position of deoxyguanosine residues in DNA is hydroxylated to produce 8-hydroxydeoxyguanosine (8-OH-dG) in DNA . by various oxygen radical-producing agents (3). T作者: 場(chǎng)所 時(shí)間: 2025-3-27 12:59 作者: Mediocre 時(shí)間: 2025-3-27 17:07 作者: uncertain 時(shí)間: 2025-3-27 19:56
A Case Study in a Chinese High School,tected mouse bone marrow cells against radiation damage even when injected an hour or more after exposure of the mice to gamma rays (2). It seems likely, therefore, that combined radiation and LA therapy may be useful for the control of selected cancers. We have begun an investigation of the combine作者: 百科全書(shū) 時(shí)間: 2025-3-28 00:39
Developments in Oncologyhttp://image.papertrans.cn/e/image/303151.jpg作者: Disk199 時(shí)間: 2025-3-28 04:44
Identification of Linoleic Acid Metabolism as a Component of the Epidermal Growth Factor Signal Trannthesis and cell division. The mitogenic signal is activated via binding of the growth factor to specific high affinity cell surface receptors and elicits a variety of biochemical changes in the cell including activation of arachidonic acid metabolism (1–7).作者: Genetics 時(shí)間: 2025-3-28 10:09
Fatty Acid-Induced Modulation of Carcinogenesis in Human and Mouse Mammary Explant Culturesy 25% of women developing breast cancer present identifiable risk factors (2). Thus, in majority of women the causative factor(s), and therefore relative risk for developing breast cancer remains unknown.作者: Scleroderma 時(shí)間: 2025-3-28 13:41 作者: 抓住他投降 時(shí)間: 2025-3-28 16:40 作者: 傻瓜 時(shí)間: 2025-3-28 19:58
Prevention of Peroxide Produced DNA Strand Scission in Human Tumor Cells by Lipoxygenase Inhibitorsor peroxides cannot be exclusively attributed to chemical interactions. That is, the “indirect” action of radiation may be mediated through rapidly initiated cellular mechanisms which lead to DNA scission rather than by hydroxyl radical reactions on the DNA molecule itself. The following experiments作者: frugal 時(shí)間: 2025-3-29 00:38
Conference proceedings 1991participation of lipid oxidation in conversion of procarcinogens, positive and negative modulation of tumor growth, immunomodulation, tissue injury, and yet protection and enhancement of cancer therapy, necessitated scientific interaction to sort out and understand these complex and sometimes contra作者: 吝嗇性 時(shí)間: 2025-3-29 04:36 作者: Suppository 時(shí)間: 2025-3-29 09:29
Liming Deng,Qiujin Chen,Yanyan Zhanglls which do not participate in the oxidative conversion of arachidonic acid into reactive intermediates. Table 1 indicates that the red blood cell and the lymphocyte (3) cannot metabolize arachidonic acid by either the cyclooxygenase or lipoxygenase pathways. Normally, one considers most cells in t作者: 龍蝦 時(shí)間: 2025-3-29 13:03 作者: 持久 時(shí)間: 2025-3-29 16:40 作者: Ophthalmoscope 時(shí)間: 2025-3-29 22:20
Eicosanoids and Other Bioactive Lipids in Cancer and Radiation InjuryProceedings of the 1作者: 得罪人 時(shí)間: 2025-3-30 02:31
Kenneth V. Honn,Lawrence J. Marnett,Thomas L. Wald作者: ineluctable 時(shí)間: 2025-3-30 05:56 作者: 飲料 時(shí)間: 2025-3-30 10:38 作者: Adulate 時(shí)間: 2025-3-30 13:25
8-Hydroxydeoxyguanosine, a DNA Adduct Formed by Oxygen Radicals: Its Implications on the Mutagenic adeoxyguanosine residues in DNA is hydroxylated to produce 8-hydroxydeoxyguanosine (8-OH-dG) in DNA . by various oxygen radical-producing agents (3). The formation of 8-OH-dG was also observed in cellular DNA when mice or rats were irradiated by ionizing radiation or administrated oxygen radical-forming carcinogens (4–6).作者: Watemelon 時(shí)間: 2025-3-30 19:32
Radiation Protection and Cancer Therapy by Linoleately, therefore, that combined radiation and LA therapy may be useful for the control of selected cancers. We have begun an investigation of the combined therapy both by clinical studies of the safety and efficacy of LA therapy in 41 dogs and 12 cats with advanced cancer and by laboratory studies.作者: GNAT 時(shí)間: 2025-3-30 21:19
