標題: Titlebook: Effects of Nicotine on Biological Systems; Franz Adlkofer (Professor of Medicine, Scientific Book 1991 Springer Basel AG 1991 Alzheimer′s [打印本頁] 作者: ATE 時間: 2025-3-21 16:08
書目名稱Effects of Nicotine on Biological Systems影響因子(影響力)
書目名稱Effects of Nicotine on Biological Systems影響因子(影響力)學科排名
書目名稱Effects of Nicotine on Biological Systems網(wǎng)絡公開度
書目名稱Effects of Nicotine on Biological Systems網(wǎng)絡公開度學科排名
書目名稱Effects of Nicotine on Biological Systems被引頻次
書目名稱Effects of Nicotine on Biological Systems被引頻次學科排名
書目名稱Effects of Nicotine on Biological Systems年度引用
書目名稱Effects of Nicotine on Biological Systems年度引用學科排名
書目名稱Effects of Nicotine on Biological Systems讀者反饋
書目名稱Effects of Nicotine on Biological Systems讀者反饋學科排名
作者: badinage 時間: 2025-3-21 22:56 作者: 通情達理 時間: 2025-3-22 00:38 作者: 瘙癢 時間: 2025-3-22 06:15
loid. Furthermore, at this conference, potential therapeutic benefits of nicotine for certain disease states were discussed. Smoking and the health effects of smoking were dealt with only as far as they could not be separated from the effects of nicotine. This volume contains the lectures presented at the sym978-3-0348-7459-5978-3-0348-7457-1作者: 其他 時間: 2025-3-22 11:18 作者: DIKE 時間: 2025-3-22 16:14 作者: DIKE 時間: 2025-3-22 20:20
Franz Adlkofer (Professor of Medicine, Scientific 作者: 誘拐 時間: 2025-3-22 23:36 作者: 含水層 時間: 2025-3-23 03:35 作者: 雄辯 時間: 2025-3-23 09:07 作者: 脆弱吧 時間: 2025-3-23 11:37
Data Science and Analytics for SMEs scientific matters concerning smoking and health. Sometimes we also advise the tobacco companies. Naturally we are interested in . aspects of smoking including the biological effects of nicotine — which is the subject of this Symposium. But we are concerned with more than just learning the latest .作者: 惡意 時間: 2025-3-23 13:55
After 2017: Managers Exit and Banks Arise, functioned as an important drug for magico-religious, medicinal, and recreational purposes. Data culled from about 1,800 ethnographic sources and pertaining to nearly 300 societies reveal that the Indians employ six major and several minor means of nicotine application. A comparison of the ethnogra作者: –吃 時間: 2025-3-23 20:37
Biswa Nath Datta,Biswajit Sahoo studies indicate rapid metabolism, which explains low oral bioavailability and physiological influence such as food on the rate of nicotine metabolism. Individual variability in rate of metabolism may explain in part individual differences in tobacco consumption and/or adverse effects of tobacco us作者: 松軟 時間: 2025-3-23 22:51 作者: 心胸狹窄 時間: 2025-3-24 04:06 作者: 揭穿真相 時間: 2025-3-24 08:36 作者: headway 時間: 2025-3-24 12:03 作者: MIRTH 時間: 2025-3-24 15:54
https://doi.org/10.1007/978-3-658-19287-7In the first study nicotine was administered intranasally to rats and a pH-dependent absorption was observed. In the second, the bioavailability of nicotine at a physiological pH was examined in man after application to different anatomical regions of the nose. The absorption was rapid and a high ab作者: refraction 時間: 2025-3-24 19:16
Maximilian E. Tschuchnig,Michael Gadermayr the capsule’s wall. In a pilot study with 5 male smokers and 5 male non-smokers, nicotine absorption and responses after application of one capsule were studied. The peak nicotine concentration in plasma was reached 10 min after application of the nicotine capsule and ranged from 4 to 10 ng/ml. In 作者: 我說不重要 時間: 2025-3-25 02:52 作者: 我還要背著他 時間: 2025-3-25 06:25
Ioannis Gkioulekas,Lazaros G. Papageorgiountitated in urine. Initial experiments found that about 50% of RIA reactive material could be removed by Extralut-3 chromatography which also retained a major portion of authentic trans 3′-hydroxycotinine added to non-smokers urine. This cotinine metabolite cross-reacted with 40% efficiency in the d作者: albuminuria 時間: 2025-3-25 09:53
,-n?chste Nachbarn und Ausrei?ererkennung,nstrated by the elimination parameters of .C-cotinine in isolated lung and liver. Phenobarbital (PB) induction markedly enhances the elimination of cotinine only in liver and not in lung..In conscious rats extrahepatic sites significantly contribute to the elimination of .C-nicotine. Hepatic first-p作者: Hippocampus 時間: 2025-3-25 11:59 作者: Eeg332 時間: 2025-3-25 19:14
https://doi.org/10.1007/978-1-4302-6599-3t occur for standard cigarette types. The NNN and NNK burden of smokers is determined by the amount of the preformed nitrosamines NNN and NNK in tobacco and their transfer into the mainstream smoke. Thus the TSNA intake of smokers can be reduced by manufacturing cigarettes with low levels of preform作者: explicit 時間: 2025-3-25 21:07 作者: 鎮(zhèn)痛劑 時間: 2025-3-26 04:02 作者: cravat 時間: 2025-3-26 07:54
Hazards in the Technical Environment,The exposure to carcinogenic nicotine-derived N-nitroso compounds from smokeless tobacco products is confined to preformed N-nitroso compounds (exogenous exposure) and not from the . nitrosation of nicotine . (endogenous exposure).作者: MOTIF 時間: 2025-3-26 11:34 作者: 諷刺 時間: 2025-3-26 15:38 作者: FIN 時間: 2025-3-26 19:42 作者: Formidable 時間: 2025-3-26 23:52
Shafi Kamalbasha,Manuel J. A. Eugsterconjugated alkaloids in 24-hour urine samples from tobacco users are 1.0, 0.5 and 2.3 for nicotine, cotinine and .-3′-hydroxycotinine, respectively. Nicotine, cotinine and .-3′-hydroxycotinine and their glucuronides together with the N-oxides of nicotine and cotinine, account for more than 90% of the ingested dose of nicotine.作者: 擁擠前 時間: 2025-3-27 04:48 作者: cravat 時間: 2025-3-27 05:56 作者: REIGN 時間: 2025-3-27 12:39
978-3-0348-7459-5Springer Basel AG 1991作者: 鐵砧 時間: 2025-3-27 14:49 作者: 蟄伏 時間: 2025-3-27 20:35 作者: defibrillator 時間: 2025-3-27 23:16
Importance of Nicotine Metabolism in Understanding the Human Biology of Nicotine studies indicate rapid metabolism, which explains low oral bioavailability and physiological influence such as food on the rate of nicotine metabolism. Individual variability in rate of metabolism may explain in part individual differences in tobacco consumption and/or adverse effects of tobacco us作者: 貪婪性 時間: 2025-3-28 03:08 作者: 芳香一點 時間: 2025-3-28 06:59
Oxidative Metabolism of Nicotine ,ute of metabolism in most mammalian species involves oxidation of the 5′-carbon atom to give the γ-lactam derivative cotinine. Oxidation of the N-methyl group results in demethylation to nornicotine, which is a minor metabolite in humans. Nicotine also undergoes oxidation of the pyrrolidine nitrogen作者: Insensate 時間: 2025-3-28 13:36
Detection of Nornicotine in Human Urine after Infusion of Nicotinernicotine has been found in the urine presenting evidence for the existence of this metabolic step. But, only less than 1% of the administered dose of nicotine is excreted as nornicotine possibly indicating rapid further metabolism.作者: 剛開始 時間: 2025-3-28 17:20
Concentration of Nicotine in Serum and Saliva after Intravenous Infusion of the Alkaloid and after Sted in two experiments. In the first experiment, four healthy male cigarette smokers received three nicotine infusions. In the second experiment, four healthy male cigarette smokers received one nicotine infusion and in addition to this, they smoked eight cigarettes of their own brand within 3 hours作者: 搜尋 時間: 2025-3-28 19:12 作者: mydriatic 時間: 2025-3-29 00:39
Nicotine Application with an Oral Capsule the capsule’s wall. In a pilot study with 5 male smokers and 5 male non-smokers, nicotine absorption and responses after application of one capsule were studied. The peak nicotine concentration in plasma was reached 10 min after application of the nicotine capsule and ranged from 4 to 10 ng/ml. In 作者: Atmosphere 時間: 2025-3-29 06:40
Conjugation Pathways in Nicotine Metabolismconjugated alkaloids in 24-hour urine samples from tobacco users are 1.0, 0.5 and 2.3 for nicotine, cotinine and .-3′-hydroxycotinine, respectively. Nicotine, cotinine and .-3′-hydroxycotinine and their glucuronides together with the N-oxides of nicotine and cotinine, account for more than 90% of th作者: BLAND 時間: 2025-3-29 08:10 作者: 洞穴 時間: 2025-3-29 13:22 作者: 侵略 時間: 2025-3-29 17:55
Relevance of Nicotine-Derived N-Nitrosamines in Tobacco Carcino-Genesis, namely N′-nitrosonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL). In animals and in human tissues these nitrosamines are metabolically activated by α-hydroxylation to highly reactive species which form adducts with pr作者: CHOIR 時間: 2025-3-29 19:46 作者: 有害 時間: 2025-3-30 03:04 作者: FRET 時間: 2025-3-30 04:16
Intestinal First Pass Metabolism of NNK in the Mousetestinal segments of mice which was further stimulated significantly by starvation and/or acetone pretreatment. Three major metabolites were tentatively identified by cochromatography with authentical reference compounds as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, 4-oxo-4-(3-pyridyl)-1-butanol作者: NAVEN 時間: 2025-3-30 10:20
Ioannis Gkioulekas,Lazaros G. Papageorgiouin the amounts of material retained by the column. The above results account for higher cotinine values than have been observed in urine when levels are compared to gas chromatography measurements and help account for the recovery of a higher proportion of metabolized nicotine.作者: Narcissist 時間: 2025-3-30 14:51
https://doi.org/10.1007/978-0-387-21528-0liver. NNN was not genotoxic in the liver up to 100 mg /kg, and the compound was only moderately positive in doses up to 500 mg/kg. No genotoxicity was observed in testes, or thymus by either compound. First results with a single cell analysis of DNA damage by . nick translation indicate both the compounds to be genotoxic in esophageal cells.作者: organism 時間: 2025-3-30 16:57 作者: BRINK 時間: 2025-3-30 20:50
Toxicokinetics of Nicotine-Derived Nitrosamines in the Ratliver. NNN was not genotoxic in the liver up to 100 mg /kg, and the compound was only moderately positive in doses up to 500 mg/kg. No genotoxicity was observed in testes, or thymus by either compound. First results with a single cell analysis of DNA damage by . nick translation indicate both the compounds to be genotoxic in esophageal cells.作者: investigate 時間: 2025-3-31 01:55
K. Mohaideen Abdul Kadhar,G. Anandm levels. After smoking nicotine values in pooled saliva from the parotid gland were about 10 times higher than those in serum. Cotinine values in saliva are slightly higher than those in serum, but the differences are marginal. TSNA could neither be detected after nicotine infusion nor after smoking.作者: Serenity 時間: 2025-3-31 05:15 作者: 率直 時間: 2025-3-31 11:29 作者: 正面 時間: 2025-3-31 15:52
Relevance of Nicotine-Derived N-Nitrosamines in Tobacco Carcino-Genesisated cancer are discussed, as is the need for developing methods for the reduction of TSNA in tobacco and tobacco smoke. Future research should concentrate on biomarkers for the exposure of tobacco users to TSNA, the DNA binding of TSNA in humans, and on the question of endogenous formation of TSNA.作者: epicondylitis 時間: 2025-3-31 18:35 作者: FUME 時間: 2025-3-31 23:42
