標(biāo)題: Titlebook: Drug Transporters in Drug Disposition, Effects and Toxicity; Xiaodong Liu,Guoyu Pan Book 2019 Springer Nature Singapore Pte Ltd. 2019 ATP [打印本頁(yè)] 作者: sprawl 時(shí)間: 2025-3-21 20:08
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity影響因子(影響力)
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity影響因子(影響力)學(xué)科排名
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity網(wǎng)絡(luò)公開度
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity被引頻次
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity被引頻次學(xué)科排名
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity年度引用
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity年度引用學(xué)科排名
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity讀者反饋
書目名稱Drug Transporters in Drug Disposition, Effects and Toxicity讀者反饋學(xué)科排名
作者: Foment 時(shí)間: 2025-3-21 23:25
Roles of Renal Drug Transporter in Drug Disposition and Renal Toxicity,s in drug pharmacokinetics and demonstrated the impact of renal transporters on the disposition of drugs, drug-drug interactions, and nephrotoxicities. Here, we focus on several important renal transporters and their roles in drug elimination and disposition, drug-induced nephrotoxicities and potential clinical solutions.作者: 迫擊炮 時(shí)間: 2025-3-22 03:57 作者: 冒煙 時(shí)間: 2025-3-22 07:32 作者: reaching 時(shí)間: 2025-3-22 12:36 作者: Pert敏捷 時(shí)間: 2025-3-22 15:44 作者: Pert敏捷 時(shí)間: 2025-3-22 19:48
Pls Record Book Bid Lot 49 Stop J Derrida,ter would be focused on the methods for the study of drug transporters in vitro, in situ/ex vivo, and in vivo. The applications, advantages, or limitations of each model and emerging technologies are also mentioned in this chapter.作者: opalescence 時(shí)間: 2025-3-22 21:59
https://doi.org/10.1007/978-1-349-20761-9resistance protein (BCRP/ABCG2) are described in more detail. The potential of ABC transporters as therapeutic targets to overcome MDR and strategies for this purpose are discussed as well as various explanations for the lack of efficacy of ABC drug transporter inhibitors to increase the efficiency of chemotherapy.作者: arbovirus 時(shí)間: 2025-3-23 02:18
Current Research Method in Transporter Study,ter would be focused on the methods for the study of drug transporters in vitro, in situ/ex vivo, and in vivo. The applications, advantages, or limitations of each model and emerging technologies are also mentioned in this chapter.作者: implore 時(shí)間: 2025-3-23 07:35 作者: 極小 時(shí)間: 2025-3-23 10:34
Xiaodong Liu,Guoyu PanFocusing on the roles of drug transporters in drug disposition, effects and toxicity.Introducing the cutting-edge developments in the study of drug transporters.Discussing the function and clinical si作者: accrete 時(shí)間: 2025-3-23 16:03 作者: Corral 時(shí)間: 2025-3-23 20:46 作者: Conflict 時(shí)間: 2025-3-23 22:26
Pls Record Book Bid Lot 49 Stop J Derrida,cific transporters. One of the largest transporter families is the ATP-binding cassette (ABC) family. More than 40 ABC transporters have been identified in human, which are divided into 7 subfamilies (ABCA to ABCG) based on their gene structure, amino acid sequence, domain organization, and phylogen作者: creatine-kinase 時(shí)間: 2025-3-24 04:31
Pls Record Book Bid Lot 49 Stop J Derrida,or transporting their substrates across biological membranes. These transporters are categorized as facilitated transporters or secondary active transporters. More than 300 . transporters have been identified. . transporters related to drug transport mainly include . gene subfamily (organic anion-tr作者: 機(jī)構(gòu) 時(shí)間: 2025-3-24 08:17 作者: Decrepit 時(shí)間: 2025-3-24 12:21
Conclusions: Changing Organisationsn of drugs. Drug transporters are generally divided into solute carrier (SLC) family and ATP binding cassette (ABC) family. Widely studied ABC family transporters include P-glycoprotein (P-GP), breast cancer resistance protein (BCRP), and multidrug resistance proteins (MRPs). SLC family transporters作者: Resection 時(shí)間: 2025-3-24 17:55
Survey,ccording to their functions, hepatic transporters can be roughly divided into influx and efflux transporters, translocating specific molecules from blood into hepatic cytosol and mediating the excretion of drugs and metabolites from hepatic cytosol to blood or bile, respectively. The function of hep作者: glucagon 時(shí)間: 2025-3-24 22:17 作者: 不舒服 時(shí)間: 2025-3-25 02:36 作者: projectile 時(shí)間: 2025-3-25 06:31 作者: 親屬 時(shí)間: 2025-3-25 08:00
The Emergence of Large-Scale Organisationsnal pigment epithelial (RPE) cells in collaboration with Bruch’s membrane and the choriocapillaris, respectively. Functions of the BRB are to regulate fluids and molecular movement between the ocular vascular beds and retinal tissues and to prevent leakage of macromolecules and other potentially har作者: delegate 時(shí)間: 2025-3-25 12:42 作者: Crohns-disease 時(shí)間: 2025-3-25 18:35 作者: 植物學(xué) 時(shí)間: 2025-3-25 22:40
Drug Transporters in Drug Disposition, Effects and Toxicity978-981-13-7647-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 拱形大橋 時(shí)間: 2025-3-26 02:43
https://doi.org/10.1007/978-981-13-7647-4ATP binding cassette transporters; Solute carrier transporters; Drug-drug interaction; Blood-tissue bar作者: 為現(xiàn)場(chǎng) 時(shí)間: 2025-3-26 05:48 作者: 休息 時(shí)間: 2025-3-26 10:54 作者: 按時(shí)間順序 時(shí)間: 2025-3-26 13:06 作者: 明確 時(shí)間: 2025-3-26 17:50 作者: PANEL 時(shí)間: 2025-3-26 23:24
Current Research Method in Transporter Study,situ/ex vivo, and in vivo methods have been established for studying transporter function and drug-transporter interaction. In this chapter, the major types of in vitro models for drug transport studies comprise membrane-based assays, cell-based assays (such as primary cell cultures, immortalized ce作者: 言行自由 時(shí)間: 2025-3-27 02:59
Transporter-Mediated Drug-Drug Interactions and Their Significance,n of drugs. Drug transporters are generally divided into solute carrier (SLC) family and ATP binding cassette (ABC) family. Widely studied ABC family transporters include P-glycoprotein (P-GP), breast cancer resistance protein (BCRP), and multidrug resistance proteins (MRPs). SLC family transporters作者: 陳腐思想 時(shí)間: 2025-3-27 05:21 作者: 考得 時(shí)間: 2025-3-27 13:23 作者: SIT 時(shí)間: 2025-3-27 16:53
Intestinal Transporter-Associated Drug Absorption and Toxicity,nt role in the rate and extent of drug absorption of some, but not all, drug molecules. Due to the heterogeneous expression of multiple transporters along the intestine, the preferential absorption sites for drugs may vary significantly. In this chapter, we aim to summarize the current research on t作者: hair-bulb 時(shí)間: 2025-3-27 20:40
Contributions of Drug Transporters to Blood-Brain Barriers,forming the blood-cerebrospinal fluid barrier (BCSFB). Their main functions are to impede free diffusion between brain fluids and blood; to provide transport processes for essential nutrients, ions, and metabolic waste products; and to regulate the homeostasis of central nervous system (CNS), all of作者: 先行 時(shí)間: 2025-3-28 01:51 作者: VERT 時(shí)間: 2025-3-28 03:32
Contributions of Drug Transporters to Blood-Placental Barrier,ental barrier are to regulate material transfer between the maternal and fetal circulation. The main functional units are the chorionic villi within which fetal blood is separated by only three or four cell layers (placental membrane) from maternal blood in the surrounding intervillous space. A seri作者: 協(xié)迫 時(shí)間: 2025-3-28 10:12
ABC Transporter-Mediated Multidrug-Resistant Cancer,d by these proteins modulates the pharmacokinetics of many drugs and xenobiotics. These transporters are involved in the pathogenesis of several human diseases. The overexpression of certain transporters by cancer cells has been identified as a key factor in the development of resistance to chemothe作者: 通情達(dá)理 時(shí)間: 2025-3-28 12:41 作者: STELL 時(shí)間: 2025-3-28 15:37 作者: 侵害 時(shí)間: 2025-3-28 19:12 作者: headway 時(shí)間: 2025-3-29 02:35
Pls Record Book Bid Lot 49 Stop J Derrida,d PEPTs are responsible for the uptake of di-/tripeptides and peptide-like drugs. MATEs are responsible for efflux of organic cations. These transporters also transport some endogenous substances, indicating that the dysfunction of SLCs not only disrupts homeostasis but also largely impacts on the d作者: LURE 時(shí)間: 2025-3-29 06:04 作者: receptors 時(shí)間: 2025-3-29 08:44 作者: Generosity 時(shí)間: 2025-3-29 14:03
Conclusions: Changing Organisationsssification system (BDDCS) put forward by Wu and Benet may help us better predict the effect of transporters on drug absorption. The drug-induced toxicity in the intestine, which may result from drug-drug interaction, gut microbiota, and bile salt toxicity, is also discussed.作者: 凝視 時(shí)間: 2025-3-29 17:18
The Emergence of Large-Scale Organisationsng tight junction proteins or altering expression and function of these transporters. This chapter will illustrate function of BBB, expression of transporters, as well as their alterations under disease status.作者: invade 時(shí)間: 2025-3-29 20:57
The Emergence of Large-Scale Organisationsmia-reperfusion) impair BRB function via altering tight junctions, RCEC death, and transporter expression. This chapter will illustrate function of BRB, expressions and functions of these transporters, and their clinical significances.作者: 冥想后 時(shí)間: 2025-3-30 01:09 作者: 咒語 時(shí)間: 2025-3-30 06:56 作者: Hallowed 時(shí)間: 2025-3-30 08:19 作者: expire 時(shí)間: 2025-3-30 16:07
