標(biāo)題: Titlebook: Drug Target Selection and Validation; Marcus T. Scotti,Carolina L. Bellera Book 2022 The Editor(s) (if applicable) and The Author(s), unde [打印本頁] 作者: 對將來事件 時(shí)間: 2025-3-21 17:57
書目名稱Drug Target Selection and Validation影響因子(影響力)
書目名稱Drug Target Selection and Validation影響因子(影響力)學(xué)科排名
書目名稱Drug Target Selection and Validation網(wǎng)絡(luò)公開度
書目名稱Drug Target Selection and Validation網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Drug Target Selection and Validation被引頻次
書目名稱Drug Target Selection and Validation被引頻次學(xué)科排名
書目名稱Drug Target Selection and Validation年度引用
書目名稱Drug Target Selection and Validation年度引用學(xué)科排名
書目名稱Drug Target Selection and Validation讀者反饋
書目名稱Drug Target Selection and Validation讀者反饋學(xué)科排名
作者: Horizon 時(shí)間: 2025-3-21 22:53 作者: 吸引人的花招 時(shí)間: 2025-3-22 01:40
Target Identification Approaches in Drug Discovery,covered by phenotypic-based screening methods. However, identifying molecular targets for these bioactive compounds is a very laborious process. With the development and advancements in new methodologies and techniques for identification and biological analysis, various target identification methods作者: 爆炸 時(shí)間: 2025-3-22 06:53
Introduction to Target Validation,riteria of drug target candidates. The selection of molecular targets with the highest potential for developing selective, effective and safe drugs depends, to a significant extent, on the correct assessment of their structural, biochemical and biological properties. The validation of a molecular ta作者: TOXIN 時(shí)間: 2025-3-22 12:47
Structure-Based Binding Pocket Detection and Druggability Assessment,odulation will interfere with disease progression, or at least alleviate disease symptoms. In addition to verifying the association between such biomolecules and the disease, target validation often involves the assessment of some relevant properties, . among them..Druggability is often defined as t作者: expunge 時(shí)間: 2025-3-22 15:54
Network-Based Target Identification,ounds. However, identification of drug targets by experiments is usually expensive and time-consuming. Therefore, various types of computational methods have been developed for prediction of drug targets over the past decade, such as molecular docking-based, pharmacophore-based, similarity-based, ma作者: expunge 時(shí)間: 2025-3-22 19:11
The Current State of Precision Medicine and Targeted-Cancer Therapies: Where Are We?,at may occur in an individual’s tumor. The goal of precision medicine is simply to deliver the right treatment to the right patient at the right dose and the right time..Precision medicine involves the collection and validation of population-wide data, including multi-omics molecular profiling data 作者: PALMY 時(shí)間: 2025-3-22 23:07 作者: 控制 時(shí)間: 2025-3-23 02:35 作者: labyrinth 時(shí)間: 2025-3-23 06:55 作者: ALOFT 時(shí)間: 2025-3-23 12:26 作者: 高興去去 時(shí)間: 2025-3-23 16:15 作者: 瘙癢 時(shí)間: 2025-3-23 20:47
Structure-Based Binding Pocket Detection and Druggability Assessment,een implied based on evolutionary relationships (using a sort of transitivity or “guilt by association” principle), or by predicting druggable pockets from different levels of structural information, without comparison with any template. The latter approximations, which will invariably depart from t作者: 胰臟 時(shí)間: 2025-3-23 23:33 作者: AGONY 時(shí)間: 2025-3-24 05:16 作者: FRONT 時(shí)間: 2025-3-24 10:02 作者: 上腭 時(shí)間: 2025-3-24 12:52 作者: corn732 時(shí)間: 2025-3-24 18:48
Q,antages as well as disadvantages. The efficient execution of every scientific process involves significant infrastructure set up and expertise in multiple disciplines (chemistry, proteomics, genomics, and bioinformatics). The collaborative work scheme comprising integrated knowledge of all of these 作者: Indolent 時(shí)間: 2025-3-24 19:03
R, chemical-based approaches can be used complementary to address this goal. In this chapter, we provide an overview of the diverse strategies available to (bio)chemically and biologically validate a molecular target and discuss important concepts in this area.作者: vitrectomy 時(shí)間: 2025-3-25 02:29 作者: Ruptured-Disk 時(shí)間: 2025-3-25 04:17 作者: 無孔 時(shí)間: 2025-3-25 07:33 作者: Stress 時(shí)間: 2025-3-25 13:37 作者: 構(gòu)成 時(shí)間: 2025-3-25 19:07 作者: Nomadic 時(shí)間: 2025-3-25 21:19 作者: 劇本 時(shí)間: 2025-3-26 03:17 作者: 反應(yīng) 時(shí)間: 2025-3-26 07:27
Q,ired biological effect. Beyond serendipitous discoveries and findings based on ethnopharmacology/traditional medicine, drug discovery in the modern age has been guided by two fundamental screening philosophies (implemented whether through in silico, in vitro or less often, in vivo approximations). O作者: –scent 時(shí)間: 2025-3-26 11:37
Q,covered by phenotypic-based screening methods. However, identifying molecular targets for these bioactive compounds is a very laborious process. With the development and advancements in new methodologies and techniques for identification and biological analysis, various target identification methods作者: 適宜 時(shí)間: 2025-3-26 14:16 作者: 手榴彈 時(shí)間: 2025-3-26 18:51 作者: linear 時(shí)間: 2025-3-26 23:58
S,ounds. However, identification of drug targets by experiments is usually expensive and time-consuming. Therefore, various types of computational methods have been developed for prediction of drug targets over the past decade, such as molecular docking-based, pharmacophore-based, similarity-based, ma作者: 學(xué)術(shù)討論會 時(shí)間: 2025-3-27 04:02
S,at may occur in an individual’s tumor. The goal of precision medicine is simply to deliver the right treatment to the right patient at the right dose and the right time..Precision medicine involves the collection and validation of population-wide data, including multi-omics molecular profiling data 作者: AV-node 時(shí)間: 2025-3-27 09:12 作者: Sleep-Paralysis 時(shí)間: 2025-3-27 13:21
Grundlagen der Wasserkraftnutzung,atics and chemoinformatics. It has also led to the maturation of subdisciplines such as food informatics, epi-informatics, and more recently, to the so-called natural products informatics. The extensive practice of informatics across different disciplines and subdisciplines has been boosted by the l作者: sundowning 時(shí)間: 2025-3-27 17:23 作者: HALL 時(shí)間: 2025-3-27 20:13 作者: avulsion 時(shí)間: 2025-3-27 23:35
Drug Target Selection and Validation978-3-030-95895-4Series ISSN 2730-5457 Series E-ISSN 2730-5465 作者: Bridle 時(shí)間: 2025-3-28 03:37 作者: 騎師 時(shí)間: 2025-3-28 08:25 作者: 歌曲 時(shí)間: 2025-3-28 12:02
Book 2022ery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis..作者: Corral 時(shí)間: 2025-3-28 15:26
,Wasserschl?sser und Schwallkammern,potential. In this chapter, we will review the MCA theoretical principles and experimental approaches to determine the . in a range of metabolic pathways such as central carbon and antioxidant metabolism, with potential application to other pathways of diverse human diseases.作者: Facilities 時(shí)間: 2025-3-28 21:29
Grundlagen der Wasserkraftnutzung,ferent tasks, with special focus/emphasis on drug discovery applications. Due to the current COVID-19 pandemic, we emphasize resources that have been developed and released over the past few months to support drug discovery efforts worldwide.作者: Oafishness 時(shí)間: 2025-3-28 23:06 作者: Apoptosis 時(shí)間: 2025-3-29 05:40
Progress on Open Chemoinformatic Tools for Drug Discovery,ferent tasks, with special focus/emphasis on drug discovery applications. Due to the current COVID-19 pandemic, we emphasize resources that have been developed and released over the past few months to support drug discovery efforts worldwide.作者: BOOR 時(shí)間: 2025-3-29 09:33
2730-5457 target identification, phenotype, and precision medicine.PreThe first book in the newly created book series, .Computer-Aided Drug Discovery and Design., focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in
