標(biāo)題: Titlebook: Drug Studies in the Elderly; Methodological Conce Neal R. Cutler (Director),Prem K. Narang (Supervis Book 1986 Plenum Publishing Corporatio [打印本頁] 作者: 令人不愉快 時(shí)間: 2025-3-21 16:39
書目名稱Drug Studies in the Elderly影響因子(影響力)
書目名稱Drug Studies in the Elderly影響因子(影響力)學(xué)科排名
書目名稱Drug Studies in the Elderly網(wǎng)絡(luò)公開度
書目名稱Drug Studies in the Elderly網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Drug Studies in the Elderly被引頻次
書目名稱Drug Studies in the Elderly被引頻次學(xué)科排名
書目名稱Drug Studies in the Elderly年度引用
書目名稱Drug Studies in the Elderly年度引用學(xué)科排名
書目名稱Drug Studies in the Elderly讀者反饋
書目名稱Drug Studies in the Elderly讀者反饋學(xué)科排名
作者: 破譯 時(shí)間: 2025-3-21 23:47 作者: 賞錢 時(shí)間: 2025-3-22 04:21
G,ictated by demographic changes. As can be seen from Fig. 1, based on current projections, the present U.S. population of older people (those 65 years of age and over) will have more than doubled by the year 2030.. It is expected that over 50 million people will belong to this group and will constitu作者: 改變立場(chǎng) 時(shí)間: 2025-3-22 06:10 作者: 大方不好 時(shí)間: 2025-3-22 09:29
H, It may be reasonable to relate the increasing incidence of infection or cancer to immune senescence. The precise contribution of changing immune competence to other diseases of aging such as Alzheimer’s disease, atherosclerosis, and diabetes must be considered speculative. However, extensive basic 作者: Pander 時(shí)間: 2025-3-22 13:02
I,ears and is followed by a gradual, often linear decline.. Many physiological and biochemical changes occur with “normal” aging. In addition, concomitant pathological conditions, lifelong habits, and environmental exposure also contribute to the biological changes in the elderly. As a result, there a作者: Pander 時(shí)間: 2025-3-22 19:40 作者: 挖掘 時(shí)間: 2025-3-23 00:23 作者: cardiac-arrest 時(shí)間: 2025-3-23 03:08 作者: 獨(dú)特性 時(shí)間: 2025-3-23 09:17
L,have been correlated with therapeutic effects. It is thus important to understand the influence of various factors such as age, disease states, and concurrent therapy on the drug’s kinetics, as these factors often alter drug pharmacokinetics (and therefore therapeutic efficacy) and are present in a 作者: 咆哮 時(shí)間: 2025-3-23 11:45 作者: 磨碎 時(shí)間: 2025-3-23 17:34 作者: 一個(gè)姐姐 時(shí)間: 2025-3-23 19:27 作者: 珊瑚 時(shí)間: 2025-3-24 00:34 作者: forager 時(shí)間: 2025-3-24 02:54
O,the elderly population with different types of dementia. It is important to clarify that the dose-response relationships with these agents in the elderly population are almost nonexistent. This difficulty associated with the clinical trials in dementia patients is primarily due to problems related t作者: Callus 時(shí)間: 2025-3-24 10:24
Epidemiology and Demography of Agingh rates have followed industrialization. Between 1880 and 1920 the impact of industrialization on demographic profiles was dramatically enhanced by a public health revolution, during which acute infectious diseases and tuberculosis became minor causes of death for the first time in history.作者: 嫻熟 時(shí)間: 2025-3-24 13:24
Physiological Changes with Aginge of importance in influencing the design and conduct of drug studies. This will be done by briefly examining those physiological changes in humans that might be expected to influence disposition of and response to drugs. This approach is being taken for several reasons.作者: KEGEL 時(shí)間: 2025-3-24 17:35 作者: 消息靈通 時(shí)間: 2025-3-24 20:14
Pharmacological Treatment of Parkinson’s Diseasene agonists; (4) monoamine oxidase inhibitors; (5) anticholinergic agents; and (6) amantadine. Levodopa is the cornerstone of Parkinsonism disease treatment. The other five drug classes are useful supplements or occasional alternatives to levodopa.作者: 可憎 時(shí)間: 2025-3-25 01:37 作者: obsolete 時(shí)間: 2025-3-25 06:02
H,e of importance in influencing the design and conduct of drug studies. This will be done by briefly examining those physiological changes in humans that might be expected to influence disposition of and response to drugs. This approach is being taken for several reasons.作者: 文字 時(shí)間: 2025-3-25 10:39 作者: COLON 時(shí)間: 2025-3-25 15:25
N,ne agonists; (4) monoamine oxidase inhibitors; (5) anticholinergic agents; and (6) amantadine. Levodopa is the cornerstone of Parkinsonism disease treatment. The other five drug classes are useful supplements or occasional alternatives to levodopa.作者: RALES 時(shí)間: 2025-3-25 19:25 作者: 背帶 時(shí)間: 2025-3-25 20:59
978-1-4684-1255-0Plenum Publishing Corporation 1986作者: 詞匯表 時(shí)間: 2025-3-26 03:25 作者: 攝取 時(shí)間: 2025-3-26 05:09 作者: 非實(shí)體 時(shí)間: 2025-3-26 11:27
Cardiovascular Changes with AgingChanges in cardiovascular anatomy and function that are specifically due to aging are often difficult to distinguish because of the high prevalence of heart and blood vessel disease among the elderly in Western cultures. .作者: 剛毅 時(shí)間: 2025-3-26 13:46
The Aging BrainThis chapter discusses the relationship between functional alterations and brain metabolism in aging animals and humans and in the pathological conditions of Alzheimer’s disease (AD).作者: PON 時(shí)間: 2025-3-26 17:16 作者: 脊椎動(dòng)物 時(shí)間: 2025-3-26 23:08
L,on. These gaps in knowledge are the result of several factors, including slow development of analytical methodology for determination of benzodiazepine concentrations in body fluids for conduct of pharmacokinetic trials and lack of drug-sensitive measures to quantify benzodiazepine pharmacodynamics.作者: 不滿分子 時(shí)間: 2025-3-27 01:06
L,ation for which the drug is intended and these patients are typically older, few studies have been conducted in which age alone was the influencing factor. Thus, much of the information presented is based on results of studies conducted in patients with arrhythmias or impaired function of another ma作者: Metamorphosis 時(shí)間: 2025-3-27 07:44
N,gical doses needed for therapeutic benefit even for the same neuromuscular illness. Some patients can be managed with small doses of corticosteroids whereas others require much higher doses; in addition, others exhibit multiple severe complications whereas others have relatively little adverse effec作者: vitrectomy 時(shí)間: 2025-3-27 12:35 作者: 坦白 時(shí)間: 2025-3-27 13:59
Neal R. Cutler (Director),Prem K. Narang (Supervis作者: 過于光澤 時(shí)間: 2025-3-27 21:29
Methodological Concerns for Clinical Trials in Geriatricson. These gaps in knowledge are the result of several factors, including slow development of analytical methodology for determination of benzodiazepine concentrations in body fluids for conduct of pharmacokinetic trials and lack of drug-sensitive measures to quantify benzodiazepine pharmacodynamics.作者: Obligatory 時(shí)間: 2025-3-28 01:26 作者: 螢火蟲 時(shí)間: 2025-3-28 02:55 作者: 不可侵犯 時(shí)間: 2025-3-28 10:19 作者: 故意 時(shí)間: 2025-3-28 10:42
The Effects of Age on Hepatic Drug Metabolismnt pathological conditions, lifelong habits, and environmental exposure also contribute to the biological changes in the elderly. As a result, there are wide differences in the rates of deterioration of organs and enzyme systems with age. Therefore, chronological aging may not necessarily be a true reflection of physiological aging.作者: 搖晃 時(shí)間: 2025-3-28 16:44
Antiepileptic Drugs in the Elderlyeven a cerebrovascular accident, may not recur, the incidence and prevalence of chronic seizures (“epilepsy”) increase with aging. Hauser and Kurland found an overall epilepsy incidence rate for Rochester, Minnesota of 5.7/1000, but 10.2/1000 for the population over 60..作者: decode 時(shí)間: 2025-3-28 21:07
G,te 15–17% of the total population. Given achievements and improvements in health care, the figure of 17% could climb as high as 25–30%. These projections are not influenced by changes in fertility rates. The older generation in 2030 will by and large be the baby boom population of the 1940s and 1950s grown older.作者: locus-ceruleus 時(shí)間: 2025-3-29 00:01 作者: 難解 時(shí)間: 2025-3-29 07:07 作者: jettison 時(shí)間: 2025-3-29 10:05
M,even a cerebrovascular accident, may not recur, the incidence and prevalence of chronic seizures (“epilepsy”) increase with aging. Hauser and Kurland found an overall epilepsy incidence rate for Rochester, Minnesota of 5.7/1000, but 10.2/1000 for the population over 60..作者: MARS 時(shí)間: 2025-3-29 13:42 作者: Oversee 時(shí)間: 2025-3-29 16:57 作者: bile648 時(shí)間: 2025-3-29 20:32 作者: HARD 時(shí)間: 2025-3-30 01:18
Cognitive Enhancers in Alzheimer’s Diseasec studies with these drugs have been few. Therefore, rather than choosing to discuss kinetics, as expected from the contributions in this part, we have decided to address methodological issues that pertain to all agents being evaluated in the elderly with some form of dementia.作者: 谷類 時(shí)間: 2025-3-30 05:58 作者: 浮雕寶石 時(shí)間: 2025-3-30 09:10
M, efficacy of β-adrenergic blocking agents in the elderly as well as the data that quantitate the altered pharmacokinetics of beta blockers in the geriatric population. In addition, we will discuss methodology that is most appropriate to study β-blocking drugs in the elderly.作者: 一回合 時(shí)間: 2025-3-30 16:04 作者: 評(píng)論性 時(shí)間: 2025-3-30 17:01
Beta Blockers in the Elderly efficacy of β-adrenergic blocking agents in the elderly as well as the data that quantitate the altered pharmacokinetics of beta blockers in the geriatric population. In addition, we will discuss methodology that is most appropriate to study β-blocking drugs in the elderly.作者: Abrade 時(shí)間: 2025-3-30 21:23
Age: A Complex Variablete 15–17% of the total population. Given achievements and improvements in health care, the figure of 17% could climb as high as 25–30%. These projections are not influenced by changes in fertility rates. The older generation in 2030 will by and large be the baby boom population of the 1940s and 1950s grown older.
