標題: Titlebook: Drug Resistance in Leishmania Parasites; Consequences, Molecu Alicia Ponte-Sucre,Maritza Padrón-Nieves Book 2018Latest edition Springer Int [打印本頁] 作者: TEMPO 時間: 2025-3-21 17:22
書目名稱Drug Resistance in Leishmania Parasites影響因子(影響力)
書目名稱Drug Resistance in Leishmania Parasites影響因子(影響力)學科排名
書目名稱Drug Resistance in Leishmania Parasites網絡公開度
書目名稱Drug Resistance in Leishmania Parasites網絡公開度學科排名
書目名稱Drug Resistance in Leishmania Parasites被引頻次
書目名稱Drug Resistance in Leishmania Parasites被引頻次學科排名
書目名稱Drug Resistance in Leishmania Parasites年度引用
書目名稱Drug Resistance in Leishmania Parasites年度引用學科排名
書目名稱Drug Resistance in Leishmania Parasites讀者反饋
書目名稱Drug Resistance in Leishmania Parasites讀者反饋學科排名
作者: 落葉劑 時間: 2025-3-21 22:22
Michael Kleiber,Ralph Joh,Roland Spano-infection, which relies on the same drugs that are used in uncomplicated . Additionally, prospects for future chemotherapeutic alternatives that target . and HIV and tackle both infections simultaneously are summarized.作者: 松緊帶 時間: 2025-3-22 01:32
Co-infection with HIVo-infection, which relies on the same drugs that are used in uncomplicated . Additionally, prospects for future chemotherapeutic alternatives that target . and HIV and tackle both infections simultaneously are summarized.作者: Incumbent 時間: 2025-3-22 08:09
Book 2018Latest edition the concept of parasitic drug resistance, its molecular basis, consequences and possible treatments. A valuable resource for scientists both from academia and industry involved in biomedical research and drug design, the book provides the knowledge needed to understand leishmaniasis and to contibute to combatting this disease worldwide..作者: LINES 時間: 2025-3-22 10:18
Carlotta de Menech,Giorgio Remottiargets, and classical as well as innovative drug targeting strategies. In addition, a combination of software and web sites has been structured here with references and tools for rapid analysis to rank and examine new target structures in ..作者: 不合 時間: 2025-3-22 14:08 作者: 不合 時間: 2025-3-22 17:05 作者: 確定 時間: 2025-3-22 22:52 作者: pessimism 時間: 2025-3-23 02:22 作者: 積云 時間: 2025-3-23 07:49 作者: 土坯 時間: 2025-3-23 11:30
Wilfried Roetzel,Bernhard Spang causes of these treatment failures are still not fully comprehended, but they are most likely a consequence of the complex interplay between parasite, host and drug. In this chapter, the generally accepted underlying factors of treatment failure are discussed along with their consequences for therapy, drug design and other related challenges.作者: Outshine 時間: 2025-3-23 14:34 作者: 金絲雀 時間: 2025-3-23 18:20
Leishmaniasis: The Biology of a Parasite,emergence of leishmaniasis, as well as its death and disability-adjusted life year toll worldwide. A better understanding of the disease itself and of drug resistance, its molecular basis, its consequences, and the definition of possible paths for better treatments may help improve this depressing p作者: 平靜生活 時間: 2025-3-24 01:24
Molecular Evolution and Phylogeny of is, in which the parasites evolved from a monoxenous ancestor on Gondwana and separated into Paraleishmania and all other species around the time when Gondwana split..Many molecular markers have demonstrated substantial intraspecies diversity and the existence of geographically and genetically isola作者: Synchronism 時間: 2025-3-24 04:52
The Role of Reservoirs: Canine Leishmaniasisnce not all infected animals develop signs of disease. This fact cannot be ignored since asymptomatic (without clinical signs) dogs are infectious to phlebotomine vectors, although at a lower risk than symptomatic (with clinical signs) dogs. The fact that dogs never achieve parasitological cure toge作者: MIRTH 時間: 2025-3-24 06:30 作者: palpitate 時間: 2025-3-24 14:15 作者: 結束 時間: 2025-3-24 17:57 作者: 自負的人 時間: 2025-3-24 22:34
American Tegumentary Leishmaniasisnd for control of the disease. The present chapter offers a description of American tegumentary leishmaniasis. a fundamental piece of knowledge for the comprehension of the challenges we face for leishmaniasis in times of drug resistance. As a way to better understand the unique scenario that Americ作者: 脫落 時間: 2025-3-25 00:12
The Role of Proteomics in the Study of Drug Resistanceiles of . spp. reveal changes in protein expression during development, determine the subcellular localization of gene products, evaluate host-parasite interactions, and elucidate drug resistance mechanisms. The characterization of these proteins has advanced, although many fundamental questions rem作者: 致命 時間: 2025-3-25 04:27
The Role of ABC Transporters in Drug-Resistant proteins with drug resistance in leishmaniasis and its fundamental role in the pathology and pharmacology of this medically important protozoan parasite that currently infects around 12 million people in the world.作者: STING 時間: 2025-3-25 08:36
P-Glycoprotein-Like Transporters in ,: A Search for Reversal Agentslike transporters, which belong to the ATP-binding cassette (ABC) superfamily of proteins. The inhibition of the function of these proteins represents an attractive way to control drug resistance in clinical environments. New natural or synthetic sesquiterpenes, flavonoids, acridonecarboxamide deriv作者: monogamy 時間: 2025-3-25 15:14 作者: 有發(fā)明天才 時間: 2025-3-25 19:00 作者: ROOF 時間: 2025-3-25 20:54 作者: Pseudoephedrine 時間: 2025-3-26 00:09 作者: 護航艦 時間: 2025-3-26 05:22
Angiogenesis: Basics of Vascular Biologyly a few cases of DR. Then, we update information on the risk factors for (re)emergence and spreading of leishmaniasis, focusing on the link between DR and TF: among others, we discuss the role of asymptomatics and animals, the importance of co-infection (considering the usual suspect HIV but also n作者: SIT 時間: 2025-3-26 09:35 作者: ANTIC 時間: 2025-3-26 14:50 作者: 使虛弱 時間: 2025-3-26 17:08 作者: tenuous 時間: 2025-3-26 21:20 作者: Encoding 時間: 2025-3-27 04:47 作者: ablate 時間: 2025-3-27 05:59
Erste Schritte in der 2D-Konstruktion,like transporters, which belong to the ATP-binding cassette (ABC) superfamily of proteins. The inhibition of the function of these proteins represents an attractive way to control drug resistance in clinical environments. New natural or synthetic sesquiterpenes, flavonoids, acridonecarboxamide deriv作者: Palpitation 時間: 2025-3-27 13:14
https://doi.org/10.1007/978-3-658-46401-1y contrast with the usual fitness cost observed in natural drug-resistant organisms and highlights parasite fitness as an important contributor to treatment failure in visceral leishmaniasis in the Indian subcontinent. In this final chapter, we will canvass the knowns and the unknowns of . fitness a作者: 駁船 時間: 2025-3-27 13:57
Alicia Ponte-Sucre,Maritza Padrón-NievesContains new chapters on metabolism.Provides detailed information on basic principles of and new findings in Leishmania and Leishmaniasis.Multi-authored with contributions of interest for both individ作者: EXCEL 時間: 2025-3-27 19:07 作者: Interstellar 時間: 2025-3-28 01:58
Rechtfertigung des Krieges: gerechter Krieg?een therapeutic failure and drug resistance. In fact, some field parasites might be naturally resistant to classical drugs and additionally, current therapies may induce drug resistance. In fact, treatment failure in leishmaniasis has multiple causes. Some are related to drugs, such as pharmacokinet作者: auxiliary 時間: 2025-3-28 05:46
Katie Spoden,Danielle Nierenbergaxonomic schemes have increasingly used molecular or biochemical characters to assign . organisms into different species, they are still heirs of the first classifications based primarily on geographical distribution, vector species, and disease presentations. The current classification system, base作者: 物質 時間: 2025-3-28 08:23
Danielle Nierenberg,Laura Reynoldss endemic and affects millions of dogs in Asia, Europe, North Africa, and South America and is considered as an emergent disease in North America. Domestic dogs (.) are the major hosts for these parasites and the main reservoir host for human infection..Recent years have seen important advances on t作者: Hypomania 時間: 2025-3-28 12:35
Angiogenesis: Basics of Vascular Biologyon-Nieves M, Diaz E (eds) Drug resistance in . parasites: consequences, molecular mechanism and possible treatments. Spinger, pp 65–83), we updated various aspects of leishmaniasis epidemiology, with a particular emphasis on their relation with parasite drug resistance (DR), with a focus on antimoni作者: 使饑餓 時間: 2025-3-28 16:04
Wolfgang Holnthoner,Andrea Banfi,Heinz Redltion. The outcome of infection depends on the parasite species as well as host genetic factors and immune competence. In order to develop a successful infection, . must evade both the innate and adaptive immune responses. Whilst protective immunity has been driven by Th1-type T cell responses, the r作者: 松馳 時間: 2025-3-28 18:52 作者: 亞當心理陰影 時間: 2025-3-29 01:35
Reference work 2010Latest editionicant subset of patients with visceral leishmaniasis were not responding to Sb. in the state of Bihar, India. Revised recommendation using ten times more drug provided a transient reprieve; however, a large proportion of patients in India and to some extent in Nepal remained unresponsive to Sb.. Div作者: liaison 時間: 2025-3-29 05:13
C1 Thermal Design of Heat Exchangerspecies and thus there are intraspecific parasitological dissimilarities that may generate different pathologies. Furthermore, in America . spp. has diverse reservoirs (that may change continuously) and can use various vectors to infect humans and mammals. Antimonials are the drugs of choice for the 作者: 除草劑 時間: 2025-3-29 10:55
Wilfried Roetzel,Bernhard Spang which had been used as mainstay of treatment for over 70?years. Even though cutaneous leishmaniasis cannot be linked to development of drug resistance, the huge species- and strain-specific variations in drug susceptibilities severely complicate effective treatment as well. A new challenge in leish作者: BOLUS 時間: 2025-3-29 13:38
C1 Berechnung von W?rmeübertragernis. However, since in . the control of gene expression relies on the stability or processing of the mature mRNA, as well as on the posttranslational modifications of proteins, the genomic sequences alone are insufficient to predict protein expression within the parasites. In this scenario, proteomic作者: ALIBI 時間: 2025-3-29 18:32 作者: 里程碑 時間: 2025-3-29 21:19 作者: finite 時間: 2025-3-30 03:20
Carlotta de Menech,Giorgio Remottirotein expression, potential targets for drug design and vaccine development are identified. Therefore, to implement successful intervention strategies against . infection, specific features of the process are critical; herein they are described, including specific genome information, good vaccine t作者: 粉筆 時間: 2025-3-30 04:39 作者: VICT 時間: 2025-3-30 09:49
https://doi.org/10.1007/978-3-658-46401-1include the presence of drugs, forcing pathogens to adapt and develop drug resistance in order to survive. The acquisition of a drug-resistant trait usually comes at a cost, making drug-resistant parasites less fit than their wild-type counterparts. This has important implications on the development作者: Ejaculate 時間: 2025-3-30 13:25 作者: 過于光澤 時間: 2025-3-30 18:51 作者: eczema 時間: 2025-3-30 21:17 作者: refine 時間: 2025-3-31 04:19 作者: anus928 時間: 2025-3-31 08:08 作者: Perineum 時間: 2025-3-31 12:46 作者: 減少 時間: 2025-3-31 14:55
The Role of the Immune System in Resistance to Infectiontion. The outcome of infection depends on the parasite species as well as host genetic factors and immune competence. In order to develop a successful infection, . must evade both the innate and adaptive immune responses. Whilst protective immunity has been driven by Th1-type T cell responses, the r作者: 休息 時間: 2025-3-31 20:50
Co-infection with HIV WHO on their management. It discusses the development of resistant . strains for existing anti-. drugs and the complexity of chemotherapy for ./HIV co-infection, which relies on the same drugs that are used in uncomplicated . Additionally, prospects for future chemotherapeutic alternatives that tar