標(biāo)題: Titlebook: Drug Discovery and Evaluation: Pharmacological Assays; Franz J. Hock Reference work 2016Latest edition Springer International Publishing S [打印本頁] 作者: 不友善 時(shí)間: 2025-3-21 18:54
書目名稱Drug Discovery and Evaluation: Pharmacological Assays影響因子(影響力)
書目名稱Drug Discovery and Evaluation: Pharmacological Assays影響因子(影響力)學(xué)科排名
書目名稱Drug Discovery and Evaluation: Pharmacological Assays網(wǎng)絡(luò)公開度
書目名稱Drug Discovery and Evaluation: Pharmacological Assays網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Drug Discovery and Evaluation: Pharmacological Assays被引頻次
書目名稱Drug Discovery and Evaluation: Pharmacological Assays被引頻次學(xué)科排名
書目名稱Drug Discovery and Evaluation: Pharmacological Assays年度引用
書目名稱Drug Discovery and Evaluation: Pharmacological Assays年度引用學(xué)科排名
書目名稱Drug Discovery and Evaluation: Pharmacological Assays讀者反饋
書目名稱Drug Discovery and Evaluation: Pharmacological Assays讀者反饋學(xué)科排名
作者: Credence 時(shí)間: 2025-3-21 21:11
Stefano Caracciolo,Matteo BalestrieriThe test is used to detect the effect of compounds on blood pressure and heart rate of anesthetized rats and to check for possible interference with adrenergic receptors. Antihypertensive agents with different mechanisms of action can be detected with this test.作者: DEMN 時(shí)間: 2025-3-22 02:16 作者: REP 時(shí)間: 2025-3-22 05:00 作者: avenge 時(shí)間: 2025-3-22 10:28 作者: 杠桿支點(diǎn) 時(shí)間: 2025-3-22 15:16
https://doi.org/10.1007/978-90-313-7661-2Eschenhagen et al. (1997) developed a method for culturing embryonic cardiomyocytes in a collagen matrix to produce a coherently contracting three-dimensional model heart tissue that allows direct measurement of isometric contractile force.作者: 杠桿支點(diǎn) 時(shí)間: 2025-3-22 19:28 作者: ligature 時(shí)間: 2025-3-22 22:32
Studies in Isolated OrgansAngus and Wright (2000) described in detail various techniques to study the pharmacodynamics of isolated large and small blood vessels.作者: 通便 時(shí)間: 2025-3-23 02:23
Cardiovascular Analysis In VivoThe test is used to detect the effect of compounds on blood pressure and heart rate of anesthetized rats and to check for possible interference with adrenergic receptors. Antihypertensive agents with different mechanisms of action can be detected with this test.作者: 即席演說 時(shí)間: 2025-3-23 08:05
Anti-Arrhythmic ActivityGuidelines for the study of arrhythmias in man and animals regarding the experimental design as well as the classification, quantification, and analysis were given as the Lambeth Conventions by Walker et al. (1988).作者: 波動(dòng) 時(shí)間: 2025-3-23 13:16 作者: HARP 時(shí)間: 2025-3-23 17:21
α- and β-Adrenoreceptor Binding.1-Adrenoceptors are widely distributed and are activated either by norepinephrine released from sympathetic nerve terminals or by epinephrine released from the adrenal medulla.作者: 悲痛 時(shí)間: 2025-3-23 22:01 作者: fiscal 時(shí)間: 2025-3-23 23:17 作者: 背書 時(shí)間: 2025-3-24 03:28 作者: DIS 時(shí)間: 2025-3-24 09:37 作者: 防水 時(shí)間: 2025-3-24 13:26 作者: SPER 時(shí)間: 2025-3-24 17:16 作者: 花爭吵 時(shí)間: 2025-3-24 18:59 作者: 熱烈的歡迎 時(shí)間: 2025-3-25 02:05 作者: TRUST 時(shí)間: 2025-3-25 04:26
Valutazione e gestione della violenzahe term calcium antagonist was introduced by Fleckenstein (1964, 1967) when two drugs, prenylamine and verapamil, originally found as coronary dilators in the Langendorff experiment, were shown to mimic the cardiac effects of simple Ca. withdrawal, diminishing Ca.-dependent high-energy phosphate uti作者: Missile 時(shí)間: 2025-3-25 09:00 作者: 口訣 時(shí)間: 2025-3-25 11:45 作者: Traumatic-Grief 時(shí)間: 2025-3-25 19:34 作者: 撫育 時(shí)間: 2025-3-25 21:50
De opbouw van het bewegingsapparaat,es are encoded by at least 28 channel subunit genes (Clapham 2003; Moran et al. 2004; Clapham et al. 2005). Six protein families comprise the mammalian TRP superfamily: the classic TRPs (TRPCs), the vanilloid receptor TRPs (TRPVs), the melastatin or long TRPs (TRPMs), the mucolipins (TRPMLs), the po作者: Neuropeptides 時(shí)間: 2025-3-26 02:20 作者: duplicate 時(shí)間: 2025-3-26 06:27 作者: exceptional 時(shí)間: 2025-3-26 11:27
Voetdiagnostiek theorie en praktijkmethod of observing the function of individual ionic channels in a variety of normal and pathological cell types. By the use of variations of the basic recording methodology, cellular function and regulation can be studied at a molecular level by observing currents through individual ionic channels 作者: 感情脆弱 時(shí)間: 2025-3-26 14:44
Voetdiagnostiek theorie en praktijkhe amplitude and duration of responses triggered by the second messengers cAMP and cGMP. The enzyme phosphodiesterase (PDE) exists in various forms. At least 11 families of phosphodiesterases have been identified (Torphy and Page 2000; Francis et al. 2001; Maurice et al. 2003; Lugnier 2006). The pro作者: conflate 時(shí)間: 2025-3-26 19:46
T. A. Grieger,D. M. Benedek,R. J. Ursanodes. They were standardized in units of an international standard. Some of the pharmacological methods used for these purposes and adopted by many pharmacopoeias have nowadays . only. This holds true for the frog method and the pigeon method (Burn et al. 1950).作者: Systemic 時(shí)間: 2025-3-26 20:59 作者: 我悲傷 時(shí)間: 2025-3-27 01:26 作者: Biofeedback 時(shí)間: 2025-3-27 07:42
Voetdiagnostiek theorie en praktijkmethod of observing the function of individual ionic channels in a variety of normal and pathological cell types. By the use of variations of the basic recording methodology, cellular function and regulation can be studied at a molecular level by observing currents through individual ionic channels (Liem et al. 1995; Sakmann and Neher 1995).作者: CBC471 時(shí)間: 2025-3-27 13:13
Positive Inotropic Activity (Cardiac Glycosides)des. They were standardized in units of an international standard. Some of the pharmacological methods used for these purposes and adopted by many pharmacopoeias have nowadays . only. This holds true for the frog method and the pigeon method (Burn et al. 1950).作者: faction 時(shí)間: 2025-3-27 14:42 作者: 艱苦地移動(dòng) 時(shí)間: 2025-3-27 20:38 作者: 脆弱帶來 時(shí)間: 2025-3-28 00:16 作者: 拋棄的貨物 時(shí)間: 2025-3-28 05:29
Storia della laparoscopia pediatricaorebrain ischemia. This damage differs from conventionally described ischemic neuronal injury because of its slow development (Ito et al. 1975; Kirono 1982; Hossman et al. 1983). The occlusion time can be varied allowing determination of various parameters, e.g., ischemia-induced amnesia.作者: 修剪過的樹籬 時(shí)間: 2025-3-28 09:14 作者: 單挑 時(shí)間: 2025-3-28 13:01 作者: delusion 時(shí)間: 2025-3-28 15:25
Disturbi somatoformi e dissociativis induced by clamping the left renal artery for 4 h. After reopening of the vessel, accumulated renin is released into circulation. The protease renin catalyzes the first and rate-limiting step in the formation of angiotensin II leading to acute hypertension. The test is used to evaluate antihypertensive activities of drugs.作者: macular-edema 時(shí)間: 2025-3-28 22:24
Schede aggiuntive al primo volume,4; Ono et al. 1984; Caffrey et al. 1986; Hausknecht et al. 1986; Fessler et al. 1988; Seifen et al. 1987, 1988; Naka et al. 1989). More recently, the rat model has been preferred (Dietz 1984, 1987; Onwochei et al. 1987; Onwochei and Rapp 1988; Kashimoto et al. 1987, 1990, 1994, 1995; Fukuse et al. 1995).作者: Interim 時(shí)間: 2025-3-29 00:43 作者: Engaged 時(shí)間: 2025-3-29 06:42 作者: CHASM 時(shí)間: 2025-3-29 10:37
Na+/H+ Exchangegel 1998). Six mammalian Na./H. exchangers, NHE1, NHE2, NHE3, NHE4, NHE5 (Attaphitaya et al. 1999; Szabo et al. 2000), and NHE6, have been described (Tse et al. 1994; Orlowski 1999; Counillon and Pouysségur 2000).作者: minimal 時(shí)間: 2025-3-29 15:23
Methods to Induce Experimental Hypertensions induced by clamping the left renal artery for 4 h. After reopening of the vessel, accumulated renin is released into circulation. The protease renin catalyzes the first and rate-limiting step in the formation of angiotensin II leading to acute hypertension. The test is used to evaluate antihypertensive activities of drugs.作者: jagged 時(shí)間: 2025-3-29 17:17 作者: 一罵死割除 時(shí)間: 2025-3-29 23:07
Phosphodiesterases and the Effects of Forskolint least 11 families of phosphodiesterases have been identified (Torphy and Page 2000; Francis et al. 2001; Maurice et al. 2003; Lugnier 2006). The properties and functions of GAF domains in cyclic nucleotide phosphodiesterases are reviewed by Zoraghi et al. (2004).作者: 榨取 時(shí)間: 2025-3-30 02:03 作者: Offbeat 時(shí)間: 2025-3-30 05:43 作者: ventilate 時(shí)間: 2025-3-30 09:43 作者: glucagon 時(shí)間: 2025-3-30 12:56
Methods to Induce Experimental Hypertensione by activation of the renin–angiotensin system. The principle can be used both for acute and chronic hypertension. In rats acute renal hypertension is induced by clamping the left renal artery for 4 h. After reopening of the vessel, accumulated renin is released into circulation. The protease renin作者: Oligarchy 時(shí)間: 2025-3-30 18:52
Coronary Drugspharmacological studies (Krayer 1931; Krayer and Mendez 1942; Somani and Blum 1966; Takeda et al. 1973; Ishikawa et al. 1978, 1983; Ono and O’Hara 1984; Ono et al. 1984; Caffrey et al. 1986; Hausknecht et al. 1986; Fessler et al. 1988; Seifen et al. 1987, 1988; Naka et al. 1989). More recently, the 作者: THROB 時(shí)間: 2025-3-30 21:55
Calcium Uptake Inhibition Activityhe term calcium antagonist was introduced by Fleckenstein (1964, 1967) when two drugs, prenylamine and verapamil, originally found as coronary dilators in the Langendorff experiment, were shown to mimic the cardiac effects of simple Ca. withdrawal, diminishing Ca.-dependent high-energy phosphate uti作者: 征兵 時(shí)間: 2025-3-31 03:55
Positive Inotropic Activity (Cardiac Glycosides)des. They were standardized in units of an international standard. Some of the pharmacological methods used for these purposes and adopted by many pharmacopoeias have nowadays . only. This holds true for the frog method and the pigeon method (Burn et al. 1950).作者: Generic-Drug 時(shí)間: 2025-3-31 06:22
Effects on Blood Supply and on Arterial and Venous Tonus without posterior communicating artery and a frequently rudimentary anterior communicating artery. Clamping of both carotid arteries induces a bilateral temporary brain ischemia (Levine and Sohn 1969; Bosma et al. 1981; Mr?ulja et al. 1983; Hossman et al. 1983; Chandler et al. 1985). This pathologi作者: 樂章 時(shí)間: 2025-3-31 12:30 作者: nocturnal 時(shí)間: 2025-3-31 15:12 作者: 雪上輕舟飛過 時(shí)間: 2025-3-31 21:30