標題: Titlebook: Drug Discovery and Development; From Targets and Mol Ramarao Poduri Book 2021 Springer Nature Singapore Pte Ltd. 2021 Drug discovery.Pharma [打印本頁] 作者: Covenant 時間: 2025-3-21 16:20
書目名稱Drug Discovery and Development影響因子(影響力)
書目名稱Drug Discovery and Development影響因子(影響力)學科排名
書目名稱Drug Discovery and Development網(wǎng)絡公開度
書目名稱Drug Discovery and Development網(wǎng)絡公開度學科排名
書目名稱Drug Discovery and Development被引頻次
書目名稱Drug Discovery and Development被引頻次學科排名
書目名稱Drug Discovery and Development年度引用
書目名稱Drug Discovery and Development年度引用學科排名
書目名稱Drug Discovery and Development讀者反饋
書目名稱Drug Discovery and Development讀者反饋學科排名
作者: intolerance 時間: 2025-3-21 21:38
Natural Products: Drug Discovery and Development,The chief sources of natural products can be broadly divided into plants, animals, marines, and microbes. The secondary metabolites produced from these living organisms have provided many useful drugs such as the anticancer drug Taxol obtained from the plant . and Halichondrin B from the marine spon作者: Hormones 時間: 2025-3-22 02:20 作者: Expostulate 時間: 2025-3-22 06:56 作者: 樹膠 時間: 2025-3-22 08:49 作者: 似少年 時間: 2025-3-22 16:54
Pharmacological Screening: Drug Discovery,. Lately, new drugs were discovered by screening extracts from natural sources on animals, subsequently on humans. The testing of agents on living beings obviously is highly expensive and often involves ethical issues. This approach of screening compounds on living systems in modern terms is called 作者: 似少年 時間: 2025-3-22 20:30 作者: Bridle 時間: 2025-3-22 23:01 作者: 幻想 時間: 2025-3-23 04:57
Discovery and Development of Stem Cells for Therapeutic Applications,ies establishing the feasibility and safety of delivering the stem cells in a clinical setting. Several applications for therapeutic use of stem cells are being explored by adopting the classical approach to drug discovery and development process with customized modifications as necessary. This chap作者: 核心 時間: 2025-3-23 08:53 作者: 不法行為 時間: 2025-3-23 12:28
Regulatory Toxicology Testing of Pharmaceuticals,trials in healthy human volunteers and patients in phased manner as per different respective regulatory agencies in which it is proposed to be marketed. Few adverse events occurred during clinical trial or post-marketing of the drugs prompted agencies and scientific community to advocate stringent n作者: 護航艦 時間: 2025-3-23 17:47 作者: 場所 時間: 2025-3-23 19:29 作者: 種屬關系 時間: 2025-3-24 01:10 作者: GROUP 時間: 2025-3-24 03:14 作者: 值得 時間: 2025-3-24 09:01 作者: 光明正大 時間: 2025-3-24 13:30
Statistics in Pharmacology and Toxicology,a presentation, and descriptive statistics, designs of an experiment, statistical inference, and regression analysis. We discussed a completely randomized design, randomized block design, Latin square design, factorial design, split plot design, and crossover design that are used in experimental and作者: 直覺沒有 時間: 2025-3-24 18:00 作者: 極深 時間: 2025-3-24 21:56 作者: sperse 時間: 2025-3-25 02:30 作者: IVORY 時間: 2025-3-25 05:06 作者: 冥想后 時間: 2025-3-25 09:03
Venous Valves in Arterialized VeinsThe basic premise of screening is that biological assays are reproducible, reliable, robust, and biologically relevant. The activities of HITs (initial actives or leads) in HTS platforms are typically confirmed in semi-manual/manual primary and secondary assays. Few selected leads further undergo it作者: Exclude 時間: 2025-3-25 14:35
Rainer Gottlob M. D.,Robert May M. D.ling approaches (e.g. physiologically based PK, empirical and population-based PK) are discussed and strategies for first-in-man dose and human PK predictions are illustrated using flow charts. Finally, applications of the aforementioned PK principles during different stages of drug discovery and de作者: 躺下殘殺 時間: 2025-3-25 18:01
Natural Products: Drug Discovery and Development,y study of the developed formulation, preclinical and clinical trial studies, and submission of New Drug Application. The developments in various chromatographic techniques like HPLC, HPTLC, and GC and spectroscopic techniques like NMR, MS, FTIR, and UV and emergence of hyphenated techniques like LC作者: 狗窩 時間: 2025-3-25 20:42
The Concept of Receptor and Molecule Interaction in Drug Discovery and Development,sed on pharmacological scales such as affinity and intrinsic efficacy, and methods to quantify them are described within a theoretical concept. Based on these two drug properties, the overt action of a drug may be agonism or antagonism. Added to this gallery are allosteric modulators (positive or ne作者: Catheter 時間: 2025-3-26 01:08
Computer-Aided Drug Design,s a huge requirement in the application of these pharmacoinformatics techniques at every stage of drug discovery. This includes the efforts in druggable target identification, target validation, target 3D structure prediction, medicinal chemistry, natural product chemistry, pharmacology (in vitro as作者: 植物群 時間: 2025-3-26 04:28
Pharmacological Screening: Drug Discovery,The basic premise of screening is that biological assays are reproducible, reliable, robust, and biologically relevant. The activities of HITs (initial actives or leads) in HTS platforms are typically confirmed in semi-manual/manual primary and secondary assays. Few selected leads further undergo it作者: DOLT 時間: 2025-3-26 11:42 作者: 發(fā)酵劑 時間: 2025-3-26 14:26
connect between academia and industry.This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable作者: Abutment 時間: 2025-3-26 18:17 作者: 短程旅游 時間: 2025-3-27 00:32 作者: 靦腆 時間: 2025-3-27 01:43
https://doi.org/10.1007/978-3-7091-8827-9n research and development of stem cells, selecting the source for stem cells, various feasible applications of stem cells, pharmacological bridging with stem cells, preclinical safety evaluation of stem cells, and finally a section on potential applications of stem cells in future.作者: absorbed 時間: 2025-3-27 05:49
Negative und komplexe Zahlen, Polynome,horough knowledge of the toxicological potential of nanocarriers. Further, the harmonious integration of academia, researcher, industries and regulatory bodies is warranted to ensure the proper regulation of their use.作者: Orgasm 時間: 2025-3-27 10:29
Genetics and Drug Discovery,iew about the mechanisms involved and aim for new drug candidates. Here in this chapter, we discuss the overview of the basic principles involved in genetics, genetic mutations, and related methods engaged in drug discovery.作者: goodwill 時間: 2025-3-27 15:56
Discovery and Development of Stem Cells for Therapeutic Applications,n research and development of stem cells, selecting the source for stem cells, various feasible applications of stem cells, pharmacological bridging with stem cells, preclinical safety evaluation of stem cells, and finally a section on potential applications of stem cells in future.作者: CHASE 時間: 2025-3-27 20:16 作者: 粘 時間: 2025-3-27 21:58 作者: 沙漠 時間: 2025-3-28 04:00 作者: 貪婪地吃 時間: 2025-3-28 06:32
Clinical Research in Pharmaceutical Drug Development,g proper endpoints, selecting correct study designs, securing quality data, and statistical analyses..As clinical research encompasses a large?part of?drug development, it is difficult to cover?the subject in detail in one chapter; hence we are providing a high-level?overview.作者: alabaster 時間: 2025-3-28 12:49 作者: Carcinoma 時間: 2025-3-28 16:44
Historical Perspective of Drug Discovery and Development,iscovery and development. The regulatory processes became stringent due to some adverse events in the second half of the twentieth century. Currently the digital and disruptive technologies are changing the scenario of drug discovery and development and producing efficacious and safe drugs.作者: ATOPY 時間: 2025-3-28 20:39
Dynamic Axial Chirality in Drug Design and Discovery: Introduction to Atropisomerism, Classificatio relevant examples of drugs both from synthetic and natural origin. The chapter further extends to deal with various methodologies involved in atropselective conversions and regulatory guidelines involved in the development of atropisomers.作者: acrimony 時間: 2025-3-28 23:33
Regulatory Toxicology Testing of Pharmaceuticals,onclinical toxicology testing. To harmonize and avoid duplication of toxicological testing on animals to get approval for marketing across the globe, ICH issued unified guidelines. The different toxicological tests which are required for the new drug approval are briefly reviewed.作者: 阻擋 時間: 2025-3-29 03:41
Pharmacovigilance,tudents to begin understanding the subject. It covers the drug safety frameworks and definitions of terms most commonly used in pharmacovigilance. Emphasis is laid on the methods used for characterization of adverse drug reactions.作者: 遺留之物 時間: 2025-3-29 10:36 作者: Popcorn 時間: 2025-3-29 13:46
Book 2021ncept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery.?The final chapters introduce readers to stem therap作者: tolerance 時間: 2025-3-29 15:59
Regulatory Process for New Drug Approval in India,ective to treat the human diseases. Prior to clinical trials in humans, the drug must have desired pharmacological activity and no toxic effects in animals. The experimental protocols to be followed need to be approved by the Ethics Committee for trial to be registered. Clinical studies are generally carried out in four stages/Phases.作者: 設施 時間: 2025-3-29 21:32
Richard Satherley,Mark W. Jonesiscovery and development. The regulatory processes became stringent due to some adverse events in the second half of the twentieth century. Currently the digital and disruptive technologies are changing the scenario of drug discovery and development and producing efficacious and safe drugs.作者: extinguish 時間: 2025-3-30 02:35 作者: COKE 時間: 2025-3-30 06:22 作者: 獸皮 時間: 2025-3-30 10:31
https://doi.org/10.1007/978-3-7643-8779-2tudents to begin understanding the subject. It covers the drug safety frameworks and definitions of terms most commonly used in pharmacovigilance. Emphasis is laid on the methods used for characterization of adverse drug reactions.作者: 事情 時間: 2025-3-30 12:49
Richard Satherley,Mark W. Jonested the natural products on self to understand the effects. Serendipity played a great role in the evolution of drug discovery. Isolation of active ingredients from plants started in the early nineteenth century. The advances in the field of chemical and biological sciences started the modern drug d作者: 蔑視 時間: 2025-3-30 16:41
Tomas Axling,Seif Haridi,Lennart FahlenThe chief sources of natural products can be broadly divided into plants, animals, marines, and microbes. The secondary metabolites produced from these living organisms have provided many useful drugs such as the anticancer drug Taxol obtained from the plant . and Halichondrin B from the marine spon作者: aphasia 時間: 2025-3-30 22:46 作者: instulate 時間: 2025-3-31 04:03
Helwig L?ffelmann,Eduard Gr?ller atropisomers behave similarly as the chiral compounds and impact the drug discovery process. The chapter deals importantly with the brief introduction to this class, nomenclature descriptors, methods to measure atropisomers racemization, and the impact of atropisomers on drug discovery and includes作者: 脆弱么 時間: 2025-3-31 08:13
Particle Tracing on Sparse GridsSAR methods help in evaluating the data emerging from pharmacology laboratories. The molecular docking methods provide atomic-level information regarding the interaction between drugs and macromolecules. The quantum medicinal chemistry methods help in evaluating the electronic structure, and provide作者: 拱墻 時間: 2025-3-31 09:28 作者: 有權 時間: 2025-3-31 13:45
Reconstruction of Venous Valves a promising drug target. It also gives an overview of various drug target classes, importance of drug target from the various aspects of drug discovery and various techniques involved in drug target identification &?validation methods.作者: packet 時間: 2025-3-31 18:35 作者: Anticlimax 時間: 2025-4-1 00:43
https://doi.org/10.1007/978-3-7091-8827-9ies establishing the feasibility and safety of delivering the stem cells in a clinical setting. Several applications for therapeutic use of stem cells are being explored by adopting the classical approach to drug discovery and development process with customized modifications as necessary. This chap
