標(biāo)題: Titlebook: Drug Discovery; A Casebook and Analy Robert A. Maxwell,Shohreh B. Eckhardt Book 1990 Springer Science+Business Media New York 1990 calcium. [打印本頁(yè)] 作者: enamel 時(shí)間: 2025-3-21 17:34
書(shū)目名稱(chēng)Drug Discovery影響因子(影響力)
作者: 有抱負(fù)者 時(shí)間: 2025-3-21 21:04 作者: Infinitesimal 時(shí)間: 2025-3-22 04:24 作者: 預(yù)知 時(shí)間: 2025-3-22 07:09 作者: Abjure 時(shí)間: 2025-3-22 10:05
Furosemide The former appellation refers loosely to the site of action of these agents within the nephron—the loop of Henle—and the latter to the fact that the maximum diuresis achieved with these drugs far exceeded that obtained with the thiazide diuretics.作者: NAIVE 時(shí)間: 2025-3-22 13:01 作者: NAIVE 時(shí)間: 2025-3-22 17:58
Cyclosporineioprine in 1959 and its subsequent combination with steroids established kidney transplantation as a viable therapy for renal failure. However, although this regimen represented a major step forward, only 50% of the allografts (homografts) achieved with it were functional, and these were accompanied作者: 顛簸下上 時(shí)間: 2025-3-23 01:17
Chlorpromazineld. Until the early 1950s it was treated with electroconvulsive shock or hypoglycemie shock induced with insulin, often resulting in memory dysfunction, amnesia, and subtle impairment of cognitive function (Taylor, 1982; Squire, 1982). In addition, drugs (barbiturates, morphine, and other sedatives)作者: 金桌活畫(huà)面 時(shí)間: 2025-3-23 01:34 作者: Foment 時(shí)間: 2025-3-23 06:14
Imipramines, it was called melancholia. It comprises two major types: (1) severe depression of mood associated with psychomotor retardation or agitation, self-reproach or guilt, as well as other symptoms, all of which occur in the apparent absence of a precipitating cause; (2) severe depression of mood associ作者: obviate 時(shí)間: 2025-3-23 10:27 作者: 不再流行 時(shí)間: 2025-3-23 17:00 作者: 甜得發(fā)膩 時(shí)間: 2025-3-23 21:17
Chlordiazepoxide and DiazepamRosenbaum, 1982). A more extensive definition was given by Rickels (1981b): “Anxiety is perceived as a subjective feeling of heightened tension and diffused uneasiness, defined as the conscious and reportable experience of intense dread and foreboding, conceptualized as internally derived and unrela作者: 課程 時(shí)間: 2025-3-24 01:44
Book 1990 along the line and to design a specific drug . . . . And so we start out to understand the disease but never get around to doing much about therapy. The authors very soon realized that there was essentially no quantitive information available on just where and how innovative therapeutic agents were作者: irritation 時(shí)間: 2025-3-24 06:19
somewhere along the line and to design a specific drug . . . . And so we start out to understand the disease but never get around to doing much about therapy. The authors very soon realized that there was essentially no quantitive information available on just where and how innovative therapeutic agents were978-1-4612-6775-1978-1-4612-0469-5作者: 終止 時(shí)間: 2025-3-24 07:54
https://doi.org/10.1007/978-3-663-12945-5t” channel for the inward movement of Ca. This slow Ca influx, which was initiated by the action potential spike, acted to trigger the contractile apparatus and thereby linked contraction with membrane excitation in the my ocardium.作者: 懶鬼才會(huì)衰弱 時(shí)間: 2025-3-24 12:01 作者: linguistics 時(shí)間: 2025-3-24 15:06 作者: PATHY 時(shí)間: 2025-3-24 21:23 作者: 排斥 時(shí)間: 2025-3-24 23:49
Chlorpromazineerapy. Chlorpromazine completely removed this impasse: it calmed highly agitated patients and dramatically improved other symptoms of psychosis. It was evident that the efficacy of chlorpromazine transcended its sedative actions. Chlorpromazine could be used regardless of age or sex, in the hospital作者: 使虛弱 時(shí)間: 2025-3-25 05:59 作者: BUMP 時(shí)間: 2025-3-25 09:36
eally does not happen as a spontaneous sequel to investiga- tive research, no matter how penetrating such research may be. Rather, it seemed to us that the discovery of innovative therapeutic agents was a very active process, existing in and of itself, and demanding full attention-it was not simply 作者: 過(guò)度 時(shí)間: 2025-3-25 12:24 作者: 遺棄 時(shí)間: 2025-3-25 18:48 作者: 量被毀壞 時(shí)間: 2025-3-25 20:52 作者: 完成 時(shí)間: 2025-3-26 02:11
Azathioprinethat there was virtually no chance for success: the host’s immune system rejected and destroyed the donated organ (Medawar, 1944,1945; Dempster, 1953; Hume et al., 1955). Hume et al. (1955) concluded, “Renal homo- transplantation has no place in the therapy of human patients at this time.”作者: Feigned 時(shí)間: 2025-3-26 07:07 作者: 軍械庫(kù) 時(shí)間: 2025-3-26 12:21 作者: 美食家 時(shí)間: 2025-3-26 15:41
https://doi.org/10.1007/978-3-663-12941-7nce, extracellular volume maintenance, and blood-pressure regulation. Moreover, some clinicians believe that it is the most significant advance yet in the diagnosis and management of hypertension (Laragh, 1984).作者: 打擊 時(shí)間: 2025-3-26 19:43
https://doi.org/10.1007/978-3-663-12947-9 decreased rate of renal excretion of Na., the primary extracellular cation (Weiner and Mudge, 1985). Associated with this retention of Na. is the retention of extracellular anion (to maintain electroneutrality) and a volume of water adequate to maintain normal osmolality.作者: 角斗士 時(shí)間: 2025-3-26 23:39 作者: FORGO 時(shí)間: 2025-3-27 04:55
Captoprilnce, extracellular volume maintenance, and blood-pressure regulation. Moreover, some clinicians believe that it is the most significant advance yet in the diagnosis and management of hypertension (Laragh, 1984).作者: Munificent 時(shí)間: 2025-3-27 08:56
Chlorothiazide decreased rate of renal excretion of Na., the primary extracellular cation (Weiner and Mudge, 1985). Associated with this retention of Na. is the retention of extracellular anion (to maintain electroneutrality) and a volume of water adequate to maintain normal osmolality.作者: Ablation 時(shí)間: 2025-3-27 10:59
Imipramineated directly with an intensely sad external situation, which is relieved by removal of the external situation. The former is referred to as endogenous depression and the latter as reactive depression.作者: 澄清 時(shí)間: 2025-3-27 15:10 作者: definition 時(shí)間: 2025-3-27 18:17
https://doi.org/10.1007/978-3-663-13885-3ing, reasonably immune-compatible relatives, or (2) where cadaver organs were given to recipients who tested as weak immune responders. Unfortunately, in the USA, the majority of the young, vigorous population requiring transplants test as strong immune responders (Kahan, 1981).作者: stroke 時(shí)間: 2025-3-28 00:50 作者: Barter 時(shí)間: 2025-3-28 02:42
https://doi.org/10.1007/978-3-663-12941-7erminals, and those of epinephrine, the agonist secreted by the adrenal medulla. The dampening of the physiological activities subserved by these endogenous agonists, especially those involving beta agonism, has had considerable and continuing therapeutic significance.作者: hankering 時(shí)間: 2025-3-28 06:24 作者: Endometrium 時(shí)間: 2025-3-28 13:29 作者: dissent 時(shí)間: 2025-3-28 17:54 作者: 暫時(shí)過(guò)來(lái) 時(shí)間: 2025-3-28 18:52
https://doi.org/10.1007/978-3-663-12947-9 The former appellation refers loosely to the site of action of these agents within the nephron—the loop of Henle—and the latter to the fact that the maximum diuresis achieved with these drugs far exceeded that obtained with the thiazide diuretics.作者: Obituary 時(shí)間: 2025-3-29 01:38
Anwendungen der Integralrechnungut much of the history of medicine. Even in relatively recent times, experiments with homografts* of skin and other organs, such as kidney, indicated that there was virtually no chance for success: the host’s immune system rejected and destroyed the donated organ (Medawar, 1944,1945; Dempster, 1953;作者: nullify 時(shí)間: 2025-3-29 05:55
https://doi.org/10.1007/978-3-663-13885-3ioprine in 1959 and its subsequent combination with steroids established kidney transplantation as a viable therapy for renal failure. However, although this regimen represented a major step forward, only 50% of the allografts (homografts) achieved with it were functional, and these were accompanied作者: 轉(zhuǎn)換 時(shí)間: 2025-3-29 10:10 作者: FEIGN 時(shí)間: 2025-3-29 13:07 作者: acetylcholine 時(shí)間: 2025-3-29 16:23 作者: 神化怪物 時(shí)間: 2025-3-29 22:50
Verschiedene Aggregationssystemeon its effects in withdrawn patients by Loomer, Saunders, and Kline (1957). These authors noted that iproniazid was the first useful drug to “energize” rather than sedate depressed patients. They considered this an important distinction when treating diseases that were associated with deep depressio作者: Dictation 時(shí)間: 2025-3-30 03:13
https://doi.org/10.1007/978-3-663-14537-0ression. This psychosis loses its intensity after periods of days or months, but, because it is typically a chronic illness, there can be frequent relapses. The mood swings can be subtle, or explosive and disruptive, and do not respond to environmental or interpersonal factors. Exaggerated symptoms 作者: 證實(shí) 時(shí)間: 2025-3-30 06:12 作者: Allure 時(shí)間: 2025-3-30 10:13 作者: 毛細(xì)血管 時(shí)間: 2025-3-30 15:03
https://doi.org/10.1007/978-3-663-12941-7erminals, and those of epinephrine, the agonist secreted by the adrenal medulla. The dampening of the physiological activities subserved by these endogenous agonists, especially those involving beta agonism, has had considerable and continuing therapeutic significance.作者: 有幫助 時(shí)間: 2025-3-30 19:54
