標(biāo)題: Titlebook: Drug Delivery; Materials Design and Eric P. Holowka,Sujata K. Bhatia Textbook 2014 Springer Science+Business Media New York 2014 Controlled [打印本頁(yè)] 作者: 強(qiáng)烈的愿望 時(shí)間: 2025-3-21 17:33
書(shū)目名稱(chēng)Drug Delivery影響因子(影響力)
作者: CHOKE 時(shí)間: 2025-3-21 22:33 作者: dura-mater 時(shí)間: 2025-3-22 03:03 作者: 同步左右 時(shí)間: 2025-3-22 07:19
https://doi.org/10.1007/978-3-662-29503-8 with a treatment that is based on a conditional relationship with a patient and rooted in technology. We say “conditional” since for every system where drugs are delivered within the human body, compromises are made between technology and physiology. Many are well aware of the defensive hurdles tha作者: 彎曲的人 時(shí)間: 2025-3-22 11:07 作者: 赤字 時(shí)間: 2025-3-22 14:20
https://doi.org/10.1007/978-3-662-29503-8these three basic parameters led to distinct profiles that identified their potential areas of application, such as embolics [2] or gel caps [3]. We can recall from Chap. . that there are various routes we can either actively or passively enter the body. The general applications were restricted in o作者: 赤字 時(shí)間: 2025-3-22 20:01
https://doi.org/10.1007/978-3-662-29503-8the advantages of bulk and surface erosion. In Chap. ., we addressed the control over fabricated shape in the form of a thin film with the effects and applications in delivery of drug dosage forms. These approaches largely focus on the viewpoint that the drug is housed in a system that is steadily o作者: 的是兄弟 時(shí)間: 2025-3-22 21:50 作者: 正式通知 時(shí)間: 2025-3-23 01:30 作者: 顯微鏡 時(shí)間: 2025-3-23 09:17 作者: 過(guò)去分詞 時(shí)間: 2025-3-23 11:18
https://doi.org/10.1007/978-3-662-29503-8dvances in multiple fields, including polymer science, molecular biology, nanotechnology, and chemical engineering. Novel structures for drug delivery incorporate hydrogels, micelles, liposomes, and thin films with unique mechanical and biological properties. These structures can be designed for res作者: 儲(chǔ)備 時(shí)間: 2025-3-23 15:20 作者: 琺瑯 時(shí)間: 2025-3-23 19:13
978-1-4939-4604-4Springer Science+Business Media New York 2014作者: 很是迷惑 時(shí)間: 2025-3-24 00:32 作者: Mundane 時(shí)間: 2025-3-24 02:21
Self-Microemulsifying Materials, applications in delivery of drug dosage forms. These approaches largely focus on the viewpoint that the drug is housed in a system that is steadily or immediately affected by its external environment.作者: 易達(dá)到 時(shí)間: 2025-3-24 09:38
https://doi.org/10.1007/978-3-662-29503-8ur discussion in Chap. . to ., traditionally entering the bloodstream through hydrolysis in the stomach, or ., done at the site of treatment. Since drug delivery encompasses a broad spectrum of treatment methodologies, we can ask two basic questions:作者: 遵循的規(guī)范 時(shí)間: 2025-3-24 14:02
https://doi.org/10.1007/978-3-662-29503-8y for these systems is to prevent interaction between the drug and physiological environment until the drug reaches the tissue target. Upon reaching the target, the system is either consumed or degraded in order to release the drug dosage form into the cellular environment. An important question that arises at this point in the discussion is作者: 狂熱文化 時(shí)間: 2025-3-24 18:35
https://doi.org/10.1007/978-3-662-29503-8ored to achieve zero-order, first-order, diffusion-controlled, or erosion-controlled delivery, or a combination of these mechanisms. Virtually every clinical discipline can benefit from new drug delivery strategies.作者: Ascribe 時(shí)間: 2025-3-24 22:10
Conclusion,ored to achieve zero-order, first-order, diffusion-controlled, or erosion-controlled delivery, or a combination of these mechanisms. Virtually every clinical discipline can benefit from new drug delivery strategies.作者: 軟弱 時(shí)間: 2025-3-25 00:21
Textbook 2014uced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary 作者: 群島 時(shí)間: 2025-3-25 06:51 作者: 允許 時(shí)間: 2025-3-25 11:10
https://doi.org/10.1007/978-3-662-29503-8 applications in delivery of drug dosage forms. These approaches largely focus on the viewpoint that the drug is housed in a system that is steadily or immediately affected by its external environment.作者: thyroid-hormone 時(shí)間: 2025-3-25 13:18
Thin-Film Materials,ur discussion in Chap. . to ., traditionally entering the bloodstream through hydrolysis in the stomach, or ., done at the site of treatment. Since drug delivery encompasses a broad spectrum of treatment methodologies, we can ask two basic questions:作者: Charlatan 時(shí)間: 2025-3-25 19:32 作者: 正面 時(shí)間: 2025-3-25 21:46 作者: 棲息地 時(shí)間: 2025-3-26 01:49
Controlled-Release Systems,proximately $150 million is invested over a 10-year period in the design and implementation of new drug offerings [1]. These drug offerings typically have a narrow therapeutic index (i.e., the difference between toxic and therapeutic levels). Additionally, there is patient-related physiological fati作者: 羊齒 時(shí)間: 2025-3-26 04:38 作者: 敲詐 時(shí)間: 2025-3-26 09:51
Self-Microemulsifying Materials,the advantages of bulk and surface erosion. In Chap. ., we addressed the control over fabricated shape in the form of a thin film with the effects and applications in delivery of drug dosage forms. These approaches largely focus on the viewpoint that the drug is housed in a system that is steadily o作者: excrete 時(shí)間: 2025-3-26 16:36
Targeted Materials,e drug dosage form. This can be approached from the perspective of engineering the material to be responsive to the environment either . or . the tissue. We discuss the first approach in this chapter and the second approach later in Chap. ..作者: 異教徒 時(shí)間: 2025-3-26 19:33
Hydrogel Materials,or enzymatic), erosion (i.e., surface or bulk), and swelling (i.e., crosslinks). In the case of swellable systems, we limited our focus only to the adjustment of swelling characteristics based on changing the crosslink density, polymer molecular weight between crosslinks, and hydrophilicity. These u作者: 結(jié)束 時(shí)間: 2025-3-26 21:42
Smart Drug Delivery Systems,sented a simple, idealized, gradual release response, which allowed for a predicted dosage to be delivered over a predictable time regime. As we shifted our discussion to encapsulated and targeted systems, it became apparent that the zero-order release would be less relevant since the design strateg作者: 四目在模仿 時(shí)間: 2025-3-27 04:48
Conclusion,dvances in multiple fields, including polymer science, molecular biology, nanotechnology, and chemical engineering. Novel structures for drug delivery incorporate hydrogels, micelles, liposomes, and thin films with unique mechanical and biological properties. These structures can be designed for res作者: Gorilla 時(shí)間: 2025-3-27 06:07
Textbook 2014nowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on “Engineering Concepts” r作者: Pessary 時(shí)間: 2025-3-27 13:13 作者: 致敬 時(shí)間: 2025-3-27 14:04 作者: ADJ 時(shí)間: 2025-3-27 18:59 作者: 連累 時(shí)間: 2025-3-28 01:20 作者: FLORA 時(shí)間: 2025-3-28 05:02
https://doi.org/10.1007/978-3-662-29503-8. At the root, the drug designer tries to address as many of these confounding properties as possible, searching for an effective chemical structure capable of treatment within an acceptable dosage window, but still there are compromises. With each new drug introduced into the pharmaceutical market,作者: 皺痕 時(shí)間: 2025-3-28 08:05
https://doi.org/10.1007/978-3-662-29503-8tistically likely to hit a bull’s-eye, but you are also more likely to damage the wall as well! A controlled-release profile can allow for targeting of the delivery, improve the availability of the drugs (i.e., short half-lives), and can serve multiple functions within the system (i.e., release syst
